scholarly journals Automated Curved and Multiplanar Reformation for Screening of the Proximal Coronary Arteries in MR Angiography

2018 ◽  
Vol 4 (11) ◽  
pp. 124
Author(s):  
Bernhard Stimpel ◽  
Jens Wetzl ◽  
Christoph Forman ◽  
Michaela Schmidt ◽  
Andreas Maier ◽  
...  

Congenital anomalies of the coronary ostia can lead to sudden death. A screening solution would be useful to prevent adverse outcomes for the affected individuals. To be considered for integration into clinical routine, such a procedure must meet strict constraints in terms of invasiveness, time and user interaction. Imaging must be fast and seamlessly integrable into the clinical process. Non-contrast enhanced coronary magnetic resonance angiography (MRA) is well suited for this. Furthermore, planar reformations proved effective to reduce the acquired volumetric datasets to 2D images. These usually require time consuming user interaction, though. To fulfill the aforementioned challenges, we present a fully automated solution for imaging and reformatting of the proximal coronary arteries which enables rapid screening of these. The proposed pipeline consists of: (I) highly accelerated single breath-hold MRA data acquisition, (II) coronary ostia detection and vessel centerline extraction, and (III) curved planar reformation of the proximal coronary arteries, as well as multiplanar reformation of the coronary ostia. The procedure proved robust and effective in ten volunteer data sets. Imaging of the proximal coronary arteries took 24 ± 5 s and was successful within one breath-hold for all patients. The extracted centerlines achieve an overlap of 0.76 ± 0.18 compared to the reference standard and the average distance of the centerline points from the spherical surface for reformation was 1.1 ± 0.51 mm. The promising results encourage further experiments on patient data, particularly in coronary ostia anomaly screening.

Author(s):  
Parkhomenko O.M. ◽  
Lozhkina N.G.

Вackground. Progressive atherosclerosis is accompanied by unfavorable clinical outcomes; study and understanding of this process is necessary to identify the appropriate risk groups. Purpose of the study to study the dynamics of atherosclerotic lesions of the coronary arteries in patients with several ischemic events in history. Patient Characterization and Research Methods. The present subanalysis included 51 patients with recurrent nonfatal myocardial infarction (MI) out of the initially included 100 patients with index MI. All 100 patients had a history of two or more ischemic coronary or cerebral events, which corresponds to the clinical signs of progressive atherosclerosis. The dynamics of the degree of coronary stenosis from the moment of index MI to repeated MI was assessed according to the data of selective coronary angiography. The statistical program Microsoft Office Excel 2019 was used. Results. All patients with recurrent myocardial infarction (51 people) had signs of progression of coronary artery stenosis: "mild" progression - 82.3%, "moderate" and "severe" - 15.6% and 2.1%, respectively. SYNTAX Score> 22.5 points was a predictor of one-year adverse outcomes: OR 6.349, CI (2.548-15.823). The results obtained make it possible to distinguish a group of patients with accelerated atherosclerosis syndrome in order to stratify the risk and optimally manage this complex category of patients.


ESC CardioMed ◽  
2018 ◽  
pp. 537-541
Author(s):  
Stephan Achenbach

Cardiac imaging by computed tomography (CT) has the unique advantage of providing a fully isotropic data set with high spatial resolution. However, the rapid motion of the heart poses substantial challenges to CT imaging. For this reason, specific techniques have been developed to increase the temporal resolution of CT imaging and to permit either image acquisition or data reconstruction in synchronization with the patient’s electrocardiogram. Next to the use of advanced scanner technology, careful patient preparation is important to avoid artefacts. This includes careful coaching and practising of the breath-hold sequence to lower the heart rate, especially when CT is used to visualize the coronary arteries. With modern scanners, radiation exposure is reasonably low and falls approximately in the range of an invasive coronary angiogram.


2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
D Siry ◽  
J Salatzki ◽  
F Andre ◽  
K Hirschberg ◽  
M Friedrich ◽  
...  

Abstract Background In acute situations such as non-ST-elevation infarction (NSTEMI) or relevant coronary artery disease (CAD) CMR does not yet play a key role due to its lengthy protocols. fSENC is a new CMR technique which may detect subclinical signs of myocardial damage by measuring myocardial strain (change in length/ unit length). A whole-heart coverage is generated in 6 heart-beats and the information obtained is converted into a colour-coded map. fSENC does not require major post-processing, long breath-holds and the administration of contrast agents/medication. Purpose In this observational study fSENC is assessed in patients with chest pain and its capability to differentiate between an ischemic cause (NSTEMI, significant CAD), an underlying non-ischemic cardiac disease and non-cardiac chest pain. Additionally, we aim to identify the affected coronary arteries in the ischemic cohort. With fSENC it could be possible to successfully diagnose patients with suspected AMI in <1h after admission and also gain diagnostic information regarding the underlying pathology. Methods Patients with chest pain and an initial hscTnT level between 5pg/ml and 52 pg/ml are recruited. These patients then undergo an fSENC-CMR before 2nd hscTnT measurement. Additionally, a stress-induced fSENC-image is acquired (1-minute hyperventilation, followed by a single breath-hold). This breathing manoeuvre leads to an increase in oxygenation through vasodilation, therefore identifying ischemic areas. The fSENC analysis is later compared to the patient's final diagnosis and therapy. Results So far 50 patients have been analysed by fSENC in this observational study (26 female, aged 57±18). fSENC correctly identified 7 patients suffering from NSTEMI or significant CAD and their affected coronary arteries. 42 other patients were safely ruled-out by fSENC which was consistent with the serial hscTnT results. In 11 patients fSENC was able to detect generalized impaired myocardial deformation, implying an underlying cardiac disease (hypertrophic cardiomyopathy, myocarditis). fSENC currently exhibits a sensitivity of 100% and specificity of 97,7% for correct rule-in/-out of an ischemic cause. Conclusions At this stage fSENC allows correct identification of patients suffering from myocardial infarction and their affected coronary arteries. Additionally, fSENC can safely rule-out patients with chest pain but no underlying ischemic cause. This novel technique is a rapid additional diagnostic tool which assesses myocardial function non-invasively without radiation exposure.


Radiology ◽  
1999 ◽  
Vol 210 (2) ◽  
pp. 566-572 ◽  
Author(s):  
Winfried Kessler ◽  
Gerhard Laub ◽  
Stephan Achenbach ◽  
Dieter Ropers ◽  
Werner Moshage ◽  
...  

2002 ◽  
Vol 15 (4) ◽  
pp. 473-478 ◽  
Author(s):  
Vibhas S. Deshpande ◽  
Steven M. Shea ◽  
Yiu Cho Chung ◽  
Richard M. McCarthy ◽  
J. Paul Finn ◽  
...  

2015 ◽  
Vol 115 ◽  
pp. S332-S333
Author(s):  
M. Mast ◽  
M. Heijenbrok ◽  
L. Van Kempen - Harteveld ◽  
A. Petoukhova ◽  
A. Scholten ◽  
...  

1994 ◽  
Vol 163 (3) ◽  
pp. 533-537 ◽  
Author(s):  
H Sakuma ◽  
G R Caputo ◽  
J C Steffens ◽  
M O'Sullivan ◽  
M W Bourne ◽  
...  

This chapter describes the anatomy of the coronary arteries and cardiac veins. It covers the coronary ostia and left coronary artery, the right coronary artery, the cardiac venous system, and the coronary sinus and its tributaries.


Sign in / Sign up

Export Citation Format

Share Document