scholarly journals Total Body Water Distribution in Breast Cancer Survivors Following Cancer Rehabilitation

2017 ◽  
Vol 2 (2) ◽  
pp. 12 ◽  
Author(s):  
Laura Stefani ◽  
Davide Palmerini ◽  
Michele Corezzi ◽  
Gabriele Mascherini ◽  
Cristian Petri ◽  
...  
Breast Care ◽  
2016 ◽  
Vol 11 (6) ◽  
pp. 428-431 ◽  
Author(s):  
Andrea Di Blasio ◽  
Teresa Morano ◽  
Giorgio Napolitano ◽  
Ines Bucci ◽  
Serena Di Santo ◽  
...  

Background: The negative side effects of breast cancer treatments can include upper limb lymphoedema. The growing literature indicates that Nordic walking is an effective discipline against several disease symptoms. The aim of this study was to determine whether introduction to Nordic walking alone is effective against total body extracellular water and upper limb circumferences in breast cancer survivors compared to its combination with a series of specifically created exercises (i.e. the Isa method). Methods: 16 breast cancer survivors (49.09 ± 2.24 years) were recruited and randomly assigned to 1 of 2 different training groups. Results: 10 lessons on Nordic walking technique plus the Isa method significantly reduced both extracellular body water and the extracellular-to-total body water ratio (p = 0.01 for both), and also the circumference of the upper limb, (both relaxed arm and forearm circumferences) (p = 0.01 for all), whereas Nordic walking alone did not. Conclusions: Introduction to Nordic walking does not seem to affect lymphoedema in breast cancer survivors. This might be because novice Nordic Walkers do not adequately generate an effective muscular pump through coordination of the alternated bimanual open-close cycle. The Isa method appears to close this gap.


1997 ◽  
Vol 82 (10) ◽  
pp. 3349-3355 ◽  
Author(s):  
Y. J. H. Janssen ◽  
P. Deurenberg ◽  
F. Roelfsema

Abstract Due to the use of various, and mostly indirect, methods to estimate total body water (TBW) and extracellular water (ECW), there is no agreement about whether body water distribution, i.e. the ECW to TBW ratio, is normal in GH-deficient (GHD) subjects at baseline and during recombinant human GH (rhGH) treatment. We studied body water distribution in 14 patients with adult-onset GHD and in 28 healthy controls. We also investigated the effect of GH replacement therapy for 4 and 52 weeks on body water distribution. All patients started with a dose of 0.6 IU rhGH/day for the first 4 weeks. After 52 weeks, the dose varied between 0.6–1.8 IU/day. TBW and ECW were measured by dilution of deuterium and bromide, respectively. Both parameters were also estimated using multifrequency bioelectrical impedance (BIA). Patients with GHD had significantly lower ECW and TBW than healthy controls. In addition, the ECW to TBW ratio was significantly lower in GHD patients than in healthy controls. Four weeks of GH treatment significantly increased body weight, TBW, ECW, and ECW/TBW. A further increase in TBW, but not ECW, was found after 52 weeks of treatment. The mean increases in TBW and ECW from the baselines were 2.5 ± 0.3 and 2.0 ± 0.3 L, respectively. The correlation coefficient and the estimated reliability between measured and estimated TBW and ECW at any time point were all high (>0.91 and >0.95, respectively). In general, both ECW and TBW were overestimated by multifrequency BIA in GHD adults. During treatment, the overestimation of both ECW and TBW diminished. The estimation error was correlated with the level of the body water compartment and the ratio of ECW to TBW. The estimated change in ECW with rhGH treatment was underestimated by multifrequency BIA. We conclude that GHD adults have lower ECW and TBW and a lower ECW to TBW ratio, as measured by dilution techniques. The ECW to TBW ratio can be normalized within 4 weeks of rhGH treatment at a dose of 0.6 IU/day. Finally, we conclude that multifrequency impedance measurements do not give valid estimates of body water compartments in the follow-up of patients with GHD.


PEDIATRICS ◽  
1951 ◽  
Vol 7 (4) ◽  
pp. 516-523
Author(s):  
ROBERT SCHWARTZ ◽  
EDWARD J. TOMSOVIC ◽  
IRVING L. SCHWARTZ

A patient with anuria in whom a rising plasma potassium concentration was associated with progressive signs of potassium intoxication exhibited a decrease in the intracellular compartment and increase of the extracellular compartment without significant change in plasma volume, while total body water remained essentially normal.


2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Jakub Kukliński ◽  
Karol P. Steckiewicz ◽  
Bartosz Sekuła ◽  
Aleksander Aszkiełowicz ◽  
Radosław Owczuk

Abstract Background Fasting prior to anesthesia is considered aspiration prophylaxis. However, prolonged food and drink restrictions may increase the risk of other complications. The aim of this study was to assess whether a carbohydrate-enriched drink (Nutricia™ preOp®), recommended by the enhanced recovery after surgery (ERAS) protocol, can improve body hydration in fasting healthy individuals. Methods Measurements were done with the bioelectric impedance analysis with a Fresenius body composition monitor. Body composition, total body water, water distribution, and hemodynamic parameters were measured at the beginning of the study and after 10 h and 12 h of fasting. Patients fasted for 10 h and then were divided into two groups: the control (n = 40) and the pre-op group (n = 41). The pre-op group received 400 mL of Nutricia™ preOp®, as suggested in the ERAS guidance. The two-tailed Student’s t test was used to compare two groups with normally distributed data and homogenous variances; if variances were heterogeneous, Welch’s test was used. The Mann-Whitney U test was used to compare two groups with non-normal data distribution. p < 0.05 was considered statistically significant. Results We found no significant differences between the control and pre-op groups regarding body water distribution and body composition. We did not observe significant losses in the total body water after fasting. Also, blood pressure was not affected by fasting. Conclusion We have proven that pre-op did not impact either body composition or body water. Trial registration ClinicalTrials.gov, NCT04665349. Registered on 11 December 2020—retrospectively registered.


1991 ◽  
Vol 71 (2) ◽  
pp. 509-513 ◽  
Author(s):  
R. W. Hoyt ◽  
M. J. Durkot ◽  
V. A. Forte ◽  
L. J. Hubbard ◽  
L. A. Trad ◽  
...  

The effects of prolonged hypoxia on body water distribution was studied in four unanesthetized adult goats (Capra lircus) at sea level and after 16 days in a hypobaric chamber [(380 Torr, 5,500 m, 24 +/- 1 degrees C); arterial PO2 = 27 +/- 2 (SE) Torr]. Total body water (TBW), extracellular fluid volume (ECF), and plasma volume (PV) were determined with 3H2O, [14C]inulin, and indocyanine green dye, respectively. Blood volume (BV) [BV = 100PV/(100 - hematocrit)], erythrocyte volume (RCV) (RCV = BV - PV), and intracellular fluid (ICF) (ICF = TBW - ECF) and interstitial fluid (ISF) (ISF = ECF - PV) volumes were calculated. Hypoxia resulted in increased pulmonary ventilation and arterial pH and decreased arterial PCO2 and PO2 (P less than 0.05). In addition, body mass (-7.1%), TBW (-9.1%), and ICF volume (-14.4%) all decreased, whereas ECF (+11.7%) and ISF (+27.7%) volumes increased (P less than 0.05). The decrease in TBW accounted for 89% of the loss of body mass. Although PV decreased significantly (-15.3%), BV was unchanged because of an offsetting increase in RCV (+39.5%; P less than 0.05). We conclude that, in adult goats, prolonged hypobaric hypoxia results in decreases in TBW volume, ICF volume, and PV, with concomitant increases in ECF and ISF volumes.


1995 ◽  
Vol 73 (3) ◽  
pp. 349-358 ◽  
Author(s):  
Paul Deurenberg ◽  
Anna Tagliabue ◽  
Frans J. M. Schouten

The relationship between total body water (TBW) and extracellular water (ECW), measured by deuterium oxide dilution and bromide dilution respectively, and impedance and impedance index (height2/impedance) at 1, 5, 50 and 100 kHz was studied. After correction for TBW, ECW was correlated only with the impedance index at 1 and 5 kHz. After correction for ECW, TBW was best correlated with the impedance index at 100 kHz. The correlation of body-water compartments with impedance values obtained with modelling programs was lower than with measured impedance values. Prediction formulas for ECW (at 1 and 5 kHz) and TBW (at 50 and 100 kHz) were developed. The prediction errors for ECW and TBW were 1·0 and 1·7 kg respectively (coefficient of variation 5%). The residuals of both ECW and TBW were related to the ECW/TBW value. Application of the prediction formulas in a population, independently measured, revealed a slight overestimation of TBW and ECW, which could be largely explained by differences in the validation group in body-water distribution and in body builds. The ratio of impedance at 1 kHz to impedance at 100 kHz was correlated with body-water distribution (ECW/TBW). The relation is however not strong enough to be useful as a predictor. It is concluded that an independent prediction of ECW and TBW, using impedance at low and high frequency respectively, is possible, but that the bias depends on the body-water distribution and body build of the measured subject.


1960 ◽  
Vol 199 (4) ◽  
pp. 661-665 ◽  
Author(s):  
Paul R. Schloerb

It was the purpose of this study to measure and to compare the volumes of distribution of creatinine, urea and tritiated water in nephrectomized dogs. After bilateral nephrectomy a solution containing known amounts of these was infused intravenously and at a constant rate in some studies. Frequent arterial blood samples were taken during and following infusion for periods up to 20 hours and were analyzed for water and the infused substances. The respective volumes of distribution and rates of dilution were calculated. Isotopic water and urea were distributed in 95% and creatinine in 61% of their final volumes of distribution at the end of a 30-minute infusion. Final equilibrium occurred in about 90 minutes with water and urea and in about 4 hours with creatinine. Creatinine became distributed in 99 ± 3% of the tritiated water volume and in 101 ± 5% of the urea volume. Urea distributed in 98 ± 4% of the tritiated water volume. It is concluded that administered creatinine is distributed in total body water of nephrectomized dogs with an equilibrium time of about 4 hours and that urea is similarly distributed within 1 1/2 hours.


2016 ◽  
Vol 29 (sup2) ◽  
pp. 26-26
Author(s):  
I. Pisani ◽  
D. Lo Presti ◽  
G. M. Tiralongo ◽  
G. Gagliardi ◽  
D. Farsetti ◽  
...  

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