scholarly journals Did the Brain and Oral Microbiota Talk to Each Other? A Review of the Literature

2020 ◽  
Vol 9 (12) ◽  
pp. 3876
Author(s):  
Yoann Maitre ◽  
Pierre Micheneau ◽  
Alexis Delpierre ◽  
Rachid Mahalli ◽  
Marie Guerin ◽  
...  
Keyword(s):  
Mental Health ◽  
Mental Disorders ◽  
Bipolar Disorders ◽  
Down’S Syndrome ◽  
Mental Health Disorders ◽  
Autism Spectrum ◽  
Oral Microbiome ◽  
Oral Microbiota ◽  
Health Disorders

This systematic review aims to investigate the role of the oral microbiome in the pathophysiology of mental health disorders and to appraise the methodological quality of research of the oral–brain axis which is a growing interest area. The PRISMA guideline was adopted, to carry out an electronic search through the MEDLINE database, to identify studies that have explored the role of the oral microbiome in the pathophysiology of mental health disorders published from 2000 up to June 2020. The search resulted in 140 records; after exclusions, a total of 22 papers were included in the present review. In accordance with the role of the oral microbiome in the pathophysiology of mental disorders, four mental disorders were identified: Alzheimer’s disease, dementia, and cognitive disorders; autism spectrum disorder; Down’s syndrome and mental retardation; and Bipolar disorders. Studies argue for correlations between oral microbiota and Alzheimer’s disease, autism spectrum disorders, Down’s syndrome, and bipolar disorders. This field is still under-studied, and studies are needed to clarify the biological links and interconnections between the oral microbiota and the pathophysiology of all mental health disorders. Researchers should focus their efforts to develop research on the oral–brain axis in the future.

scholarly journals PERSON-ENVIRONMENT MISFIT AND MENTAL DISORDER AMONG PHD STUDENTS: THE MEDIATING ROLE OF MEANINGFUL WORK

2021 ◽  
Author(s):  
Francesco Tommasi ◽  
◽  
Andrea Ceschi ◽  
Riccardo Sartori
Keyword(s):  
Mental Health ◽  
Mental Disorders ◽  
Working Conditions ◽  
Environmental Conditions ◽  
Meaningful Work ◽  
Mental Health Disorders ◽  
Intention To Quit ◽  
Mediating Role ◽  
Health Disorders

"In organizational psychology, the authors’ awareness of the concerns about the current academic working conditions and their potential impacts on PhD students’ mental health is increasing. Accordingly, authors have witnessed increased the attention to PhD students’ perception of their fit with the environmental conditions, i.e., organizational policies, co-workers’ and supervisors’ relations and supports, as an antecedent of their PhD experience. In particular, such environmental conditions seem to be related to the high diffusion of state anxiety and depression among PhD students that perceive a certain level of misfit between them and the environment. However, studies suggested that, despite the working conditions, in the presence of positive experience at work, such as meaningful work, individuals are less at risk of developing mental disorders as well as of quitting their job. Indeed, meaningful work construct regards a positive individual phenomenon of experience and perception of meaningfulness at work. Then, it might be a potential experience that might mitigate the experience of negative states at work. The present paper aims to address the current need for knowledge by involving a literature review of the role played by meaningful work in the PhD experience. Then, the paper explores the potential mediational role of meaningful work between the path from P-E misfit and mental disorders’ symptoms and students’ intention to quit. A cross-sectional study has been devised via the use of an online questionnaire with self-report measures on P-E misfit, meaningful work, mental health disorders symptoms, and intention to quit. In a sample of N = 251 Italian PhD students, the results showed a prevalence of three mental health disorders symptoms, i.e., depression, anxiety and hostility, among doctorate students, which resulted to be positively related to the levels of P-E misfit. Then, the results showed a negative mediating role of meaningful work on the paths from P-E misfit to (a) mental disorders and (b) intention to quit. Finally, the paper advances further steps for research as well as for practical implications for supporting PhD students."

Addressing Pediatric Developmental and Mental Health in Primary Care Using Tele-Education

2021 ◽  
pp. 000992282110596
Author(s):  
Joyce N. Harrison ◽  
Janna Steinberg ◽  
Anna Maria Louise Wilms Floet ◽  
Nancy Grace ◽  
Deepa Menon ◽  
...  
Keyword(s):  
Mental Health ◽  
Early Childhood ◽  
Mental Health Disorders ◽  
Knowledge Gain ◽  
Atlantic Region ◽  
School Based ◽  
Health Disorders ◽  
Management Changes ◽  
Provision Of Care

This study evaluates the effectiveness of an early childhood tele-education program in preparing community pediatric clinicians to manage developmental and mental health disorders in young children. Community pediatric clinicians from rural, underserved, or school-based health center practices in the mid-Atlantic region participated in a weekly tele-education videoconference. There was a significant knowledge gain evidenced by the percentage of questions answered correctly from pre- to post- didactic exposure ( P < .001). Participants reported an increase in knowledge from pre- ( P < .001) and in confidence from pre- to post- participation ( P < .001). Practice management changes demonstrated an encouraging trend toward managing patients in the Medical Home, as compared with immediately deferring to specialists following participation. This early childhood tele-education videoconferencing program is a promising response to the urgent need to confidently increase the role of pediatricians in the provision of care for childhood developmental and mental health disorders.

The Role of Symptoms in the Recognition of Mental Health Disorders in Primary Care

2003 ◽  
Vol 44 (5) ◽  
pp. 402-406 ◽  
Author(s):  
János Füredi ◽  
Sándor Rózsa ◽  
János Zámbori ◽  
Erika Szádóczky
Keyword(s):  
Mental Health ◽  
Primary Care ◽  
Mental Health Disorders ◽  
Health Disorders

Anticancer, Anxiolytic, Nootropic Effects of Convolvulus Pluricaulis

2021 ◽  
pp. 1-1
Author(s):  
Rashmi Sharma ◽  
Keyword(s):  
Mental Health ◽  
Mental Disorders ◽  
Mental Health Disorders ◽  
Low Energy ◽  
Suicidal Thinking ◽  
Health Disorders ◽  
Convolvulus Pluricaulis

Mental health disorders effect thinking, behave, mood etc. these can be schizophrenia, eating beh. Addictive beh, Depression, anxiety, feeling sad, down, fear, worry, guilt, anger, violence & suicidal thinking. Convolvulus is traditionally used to treat mental disorders insomnia, fatigue, low Energy

The Use of Mobile and Wearable Artificial Intelligence in Child and Adolescent Psychiatry – A Scoping Review (Preprint)

2021 ◽  
Author(s):  
Victoria Welch ◽  
Tom Joshua Wy ◽  
Anna Ligezka ◽  
Leslie C. Hassett ◽  
Paul E. Croarkin ◽  
...  
Keyword(s):  
Mental Health ◽  
Artificial Intelligence ◽  
Scoping Review ◽  
Adolescent Psychiatry ◽  
Child And Adolescent ◽  
Mental Health Disorders ◽  
Wearable Devices ◽  
Autism Spectrum ◽  
Child And Adolescent Psychiatry ◽  
Health Disorders

BACKGROUND Mental health disorders across the life span are a leading cause of medical disabilities. This burden is particularly significant in children and adolescents due to challenges in diagnoses and lack of precision medicine approaches. The advent and widespread adoption of wearable devices (e.g., smartwatches) that generate large volumes of passively collected data that are conducive for artificial intelligence applications to remotely diagnose and manage child and adolescent mental health disorders is promising. OBJECTIVE This study conducted a scoping review to study, characterize and identify areas of innovations with wearable devices that can augment current in-person physician assessments to individualize diagnosis and management of mental health disorders in child and adolescent psychiatry. METHODS This scoping review used PRISMA’s information as a guide. A comprehensive search of several databases from 2011 to June 25, 2021, limited to English language and excluding animal studies, was conducted. The databases included Ovid MEDLINE (R) and Epub Ahead of Print, In-Process & Other Non-Indexed Citations and Daily, Ovid Embase, Ovid Cochrane Central Register of Controlled Trials, Ovid Cochrane Database of Systematic Reviews, Web of Science, and Scopus. RESULTS The initial search yielded 344 articles. 19 articles were left on the final source list for this scoping review. Articles were divided into three main groups: Studies with the main focus on Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorders (ADHD) and Internalizing disorders such as anxiety disorders. Majority of the studies used either ECG strap or wrist worn biosensor. CONCLUSIONS Our scoping review found large heterogeneity of methods and findings in artificial intelligence studies in child psychiatry. Overall, the largest gaps identified in this scoping review are the lack of randomized control trials, most available studies are pilot feasibility trials.

The Role of Rural and Urban Geography and Gender in Community Stigma Around Mental Illness

2020 ◽  
pp. 109019812097496
Author(s):  
Shawnda Schroeder ◽  
Chih Ming Tan ◽  
Brian Urlacher ◽  
Thomasine Heitkamp
Keyword(s):  
Mental Health ◽  
Mental Illness ◽  
Rural Areas ◽  
Mental Health Disorders ◽  
Mental Illness Stigma ◽  
Stigma Scale ◽  
Rural And Urban ◽  
Health Disorders ◽  
And Gender

Empirical evidence describes the negative outcomes people with mental health disorders experience due to societal stigma. The aim of this study was to examine the role of gender and rural-urban living in perceptions about mental illness. Participants completed the Day’s Mental Illness Stigma Scale, a nationally validated instrument for measuring stigma. Directors of Chambers of Commerce in North Dakota distributed the electronic survey to their members. Additionally, distribution occurred through use of social media and other snowball sampling approaches. Analysis of data gathered from 749 participants occurred through examination of the difference in perceptions based on geography and gender. The zip codes of residence were sorted to distinguish between rural and urban participants. Application of weighting measures ensured closer alignment with the general population characteristics. Findings indicate that for the majority of the seven stigma measures the Day’s Mental Illness Stigma Scale examines, the coefficient of rural–gender interactions was positive and highly significant with higher levels of stigma in rural areas. Females exhibited lower stigma perceptions than males. However, women living in rural areas held higher degrees of stigma compared to urban residing females. Implications of the study include the need to advance mental health literacy campaigns for males and people residing in rural communities. Additional empirical studies that examine the role of geography and gender in understanding stigma toward people with mental health disorders will result in improved treatment outcomes due to increased and focused educational efforts.

scholarly journals The Microbiota-Gut-Brain Axis in Mental Health and Medication Response: Parsing Directionality and Causality

2021 ◽  
Vol 24 (3) ◽  
pp. 216-220
Author(s):  
Thomaz F S Bastiaanssen ◽  
John F Cryan
Keyword(s):  
Mental Health ◽  
Side Effects ◽  
Anxiety Disorders ◽  
Psychotropic Drugs ◽  
Gut Microbiome ◽  
Alpha Diversity ◽  
Mental Health Disorders ◽  
Longitudinal Cohort ◽  
Health Disorders

Abstract There is increasing evidence for the role of the microbiome in various mental health disorders. Moreover, there has been a growing understanding of the importance of the microbiome in mediating both the efficacy and side effects of various medications, including psychotropics. In this issue, Tomizawa and colleagues report on the effect of psychotropic drugs on the gut microbiome of 40 patients with depression and/or anxiety disorders. In their longitudinal cohort, the authors find that antipsychotics, but not anxiolytics, decrease microbiome alpha diversity. They further find that antipsychotics dosage was negatively correlated with alpha diversity in these patients. The health consequences of these microbiome alterations remain to be fully understood. In this commentary, we will discuss such findings through the lens of several recent studies on the microbiota-gut-brain axis. We also use the paper as a backdrop to discuss directionality and, by extension, causality in relation to microbiota-gut-brain-brain signaling.

scholarly journals The aetiology of social deficits within mental health disorders: The role of the immune system and endogenous opioids

2019 ◽  
Author(s):  
Sarah Jane Charles ◽  
Miguel Farias ◽  
R. I. M. Dunbar
Keyword(s):  
Mental Health ◽  
Immune System ◽  
Mental Health Disorders ◽  
Social Bonding ◽  
Endogenous Opioids ◽  
Future Research ◽  
Endogenous Opioid System ◽  
Endogenous Opioid ◽  
Health Disorders

The American National Institute for Mental Health (NIMH) has put out a set of research goals that include a long-term plan to identify more reliable endogenous explanations for a wide variety of mental health disorders (Insel, 2013). In response to this, we have identified a major symptom that underlies multiple mental health disorders – social bonding dysfunction. We suggest that endogenous opioid abnormalities can lead to altered social bonding, which is a symptom of various mental health disorders, including depression, schizophrenia and ASD. This article first outlines how endogenous opioids play a role in social bonding. Then we show their association with the body’s inflammation immune function, and review recent literature linking inflammation to mental health ‘immunophenotypes’. We finish by explaining how these immunophenotypes may be caused by alterations in the endogenous opioid system. This is the first overview of the role of inflammation across multiple disorders where we provide a biochemical explanation for why immunophenotypes might exist across diagnoses. We propose a novel mechanism of how the immune system may be causing ‘sickness-type’ behaviours (fatigue, appetite change, social withdrawal and inhibited motivation) in those who have these immunophenotypes. We hope that this novel aetiology can be used as a basis for future research in mental health.

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