scholarly journals Comparison of the Visibility of Fetal Tooth Buds on 1.5 and 3 Tesla MRI

2020 ◽  
Vol 9 (11) ◽  
pp. 3424
Author(s):  
Burkhard Kunzendorf ◽  
Mariana C. Diogo ◽  
Delfina I. Covini ◽  
Michael Weber ◽  
Gerlinde M. Gruber ◽  
...  

Dental anomalies coincide with genetic disorders, and prenatal identification may contribute to a more accurate diagnosis. The aim of this study was to assess whether fetal Magnet Resonance Imaging (MRI) is suitable to visualize and investigate intrauterine dental development in the upper jaw, and to compare the quality of visibility of tooth buds between 1.5 Tesla (T) and 3T images. MR images of fetuses Gestational Week (GW) 26.71 ± 4.97 from 286 pregnant women with diagnoses unrelated to dental anomalies were assessed by three raters. We compared the visibility between groups and field strengths in five gestational age groups, using chi square and Fisher’s exact tests. All ten primary tooth buds were identifiable in 5.4% at GW 18–21, in 75.5% at GW 26–29, and in 90.6% at GW 34+. Before GW 30, more tooth buds were identifiable on 3T images than on 1.5T images. Statistical significance was only reached for identification of incisors (p = 0.047). Therefore, 1.5T and 3T images are viable to visualize tooth buds, particularly after GW 25, and their analysis may serve as diagnostic criterion. MRI tooth bud data might have an impact on various fields of research, such as the maldevelopment of teeth and their causes. Analyzing tooth buds as an additional diagnostic criterion is not time consuming, and could lead to an improvement of syndrome diagnosis.

Author(s):  
Patrícia Paixão Fayer ◽  
Maria Marta Conrado ◽  
Luciano Miranda ◽  
Renato Melo Ferreira ◽  
Everton Rocha Soares ◽  
...  

Introdução: Nas últimas décadas aumentou o número de pessoas acima do peso, incluindo crianças e adolescentes, fato que é considerado preocupante, pois pode acarretar diversas doenças crônicas, em longo prazo.Objetivo: Avaliar a prevalência de sobrepeso e obesidade em escolares de um colégio militar, investigando possíveis diferenças entre os sexos e as faixas etárias.Métodos: Estudo quantitativo, transversal, do qual participaram 381 escolares de um colégio militar de Minas Gerais, de 11 a 17 anos, sendo 213 meninos e 168 meninas. Calculou-se o índice de massa corporal (IMC) que foi classificado segundo o PROESP-BR. Para testar diferenças entre os sexos, utilizou-se o teste do Qui-Quadrado (X2) e para testar a relação entre idade e IMC, utilizou-se a correlação de Pearson. Significância estatística: p < 0,05.Resultados: Foi observado sobrepeso em 17,8% (n = 68) e de obesidade em 5,8% (n = 22) dos escolares. Houve correlação positiva entre a idade cronológica e o IMC (r = 0,32; p < 0,0001). Não houve correlação entre estado nutricional e faixa etária. Não foram observadas diferenças significativas entre os sexos, em relação ao sobrepeso e à obesidade (16,9% e 6,6% nos meninos vs. 19,0% e 4,8% nas meninas, respectivamente).Conclusão: A prevalência sobrepeso e obesidade nos escolares do colégio militar, em conjunto, foi de 23,6%, tanto nos meninos quanto nas meninas, sem diferença significativa entre as faixas etárias. Essa prevalência foi similar à média de escolares brasileiros.Prevalence of Overweight and Obesity in Students of a Military SchoolIntroduction: Over the past few decades, the number of overweight people, including children and adolescents has increased significantly, a fact that is considered worrying, as it can lead to several chronic diseases in the long term.Objective: To evaluate the prevalence of overweight and obesity in schoolchildren of a military college, investigating possible differences between sexes and age groups.Methods: A quantitative, cross-sectional study was carried out in which 381 students from a military school in Minas Gerais, aged 11 to 17 years, were 213 boys and 168 girls. The body mass index (BMI) was calculated according to the PROESP-BR. To test for gender differences, the Chi-square test (X2) was used and Pearson's correlation was used to test the relationship between age and BMI. Statistical significance: p <0.05.Results: Overweight was observed in 17.8% (n = 68) and obesity in 5.8% (n = 22) of the students. There was a positive correlation between chronological age and BMI (r = 0.32; p <0.0001). There was no correlation between nutritional status and age range. No significant differences were observed between genders regarding overweight and obesity (16.9% and 6.6% in boys vs. 19.0% and 4.8% in girls, respectively).Conclusion: The prevalence of overweight and obesity in the students of the military college, together, was 23.6% in both boys and girls, with no significant difference between age groups. This prevalence was similar to the average of Brazilian schoolchildren.


2021 ◽  
Vol 10 (24) ◽  
pp. 1830-1834
Author(s):  
Amith Adyanthaya ◽  
Risana K ◽  
Aparna Sivaraman ◽  
Gopika Gopan A ◽  
Nazreen Ayub K. ◽  
...  

BACKGROUND We wanted to clinically evaluate the efficacy of lidocaine bioadhesive patches for extraction in paediatric dentistry and assess the comfort and pain response by sound eye motor (SEM) scale and intensity of pain using the visual analogue scale (VAS). METHODS A total of thirty-five co-operative children of age group 8 - 12 years without systemic diseases who needed dental extraction participated in the study. Extraction was carried out using customized lidocaine bioadhesive patches as anaesthetic agent. Evaluation of comfort and pain response was done by sound eye motor scale and intensity of pain using the visual analogue scale. Statistical analysis was done with SPSS version 2.0. Comparison of SEM scale and VAS scores between different subgroups was done using a chi-square test. P value less than 0.001 was considered statistically significant. RESULTS Children of higher age groups belonging to both the genders demonstrated less perception to pain during extractions using lidocaine patch. During extraction of firm teeth and teeth with Grade I mobility, perception of pain was more in girls. Maxillary arch extraction in children with various grades of mobility perceived less pain. Irrespective of age, gender and arches,teeth with Grade II and Grade III mobility were extracted with minimal VAS and SEM score. CONCLUSIONS Bioadhesive patches serve as a potential non-invasive alternative to traditional modes of local anaesthetic delivery with the advantage of eliminating needle phobia and possible negative influence on the behaviour. KEY WORDS Bioadhesive Patches, Lidocaine, Extraction, Paediatric Dentistry


2019 ◽  
pp. 44-49

Introduction: Trans-rectal palpation (TRP) is the examination of the internal genitalia of female large animals which is carried out via the rectum and taught mostly during the clinical years of veterinary training. This study was conducted to evaluate the essence of TRP to veterinary medicine programme in Nigerian veterinary schools in Southern Nigeria. Methods: One hundred final year students were randomly selected from two veterinary schools to fill prepared questionnaire. The first part was on bio-data of respondents. The second part tested knowledge of students on anatomy and physiology of reproductive organ/system in cow. The last section dealt with extent of their involvement in TRP, frequency of palpation with live animal, impact of the training on skill development and their confidence on using this technique post-graduation. The data were presented with descriptive statistics (frequent and percentage). Association between frequency of palpation and confidence to employ TRP during clinical service post-graduation was tested with Chi square and statistical significance was established at p < 0.05. Results: More male students (65%) than female (35%) responded to the survey. Most respondents (43%) were within age group 25-30 years compared to <25 and >30 years age groups. The students demonstrated good knowledge of anatomy and physiology of the reproductive tract of cow with 72% having high scores (? 75%). The majority of the students (90%) were able to use live animals for TRP exercise, out of which only 25 (28%) had performed palpation on a live cow (?3×). There was a strong (p > 0.05) association between frequency of palpation and the confidence displayed by respondents to use the method post-graduation. Significance: It is recommended that students should be taught TRP with live animals possibly by being involved in ante mortem inspection of cattle meant for slaughter at the abattoir.


2015 ◽  
Vol 3 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Mario Rodrigues Melo Filho ◽  
Verônica Oliveira Dias ◽  
Daniella Reis Martelli ◽  
Lívia Ribeiro Paranaíba ◽  
Mário Sérgio Oliveira Swerts ◽  
...  

The purpose of the present study was to evaluate the prevalence of teeth malposition (rotated) in Brazilian patients with oral clefts and to contribute to the definition of subphenotypes. This study included 317 patients with nonsyndromic cleft lip with or without cleft palate. Tooth malposition was assessed clinically, through radiographs, and medical history records for each individual. Only teeth malpositions outside the area of the clefts were included. Comparisons were assessed by cross-tabulation and standard chi-square test, and statistical significance was set at p≤0.05. Cleft lip and palate was more prevalent in males, while cleft palate was more common in females. Regarding the presence of tooth malposition, of the 317 patients, 92 (29.02%) had at least one tooth with the dental anomaly. Tooth malposition was more common in patients with cleft lip and palate (16.1%), followed by, respectively, cleft palate (6.9%) and cleft lip (6%) (p=0.112). The highest occurrence of tooth malposition was in the mandible and involved the canines (p<0.01). Few studies have investigated the prevalence of tooth malposition in individuals with nonsyndromic cleft lip with or without cleft palate. Our results confirmed the highest occurrence of dental anomalies, particularly tooth malposition, in patients with oral clefts. Our findings also highlight that there was a higher occurrence of this condition in the mandible and not the maxilla.


2019 ◽  
Vol 3 (2) ◽  

Radiographic Mandibular Indices serve as easy and relatively cheap tools for evaluating bone mineralization. Objectives: To examine the effect of age and gender on three mandibular indices: the panoramic mandibular index (PMI), the mandibular ratio (MR) and the mandibular cortical index (MCI), among Libyan population. Methods: The three indices were measured on 317 digital (OPGs) of adult humans (155 males, 162 females). The sample was divided into six age groups (from 18-25 years through 56-65 years). The measurements were analyzed for interactions with age and sex, using SPSS (Statistical Package for Social Studies) software version no. 22. The tests employed were two way ANOVA, the unpaired T-test and chi-square test. Results: The mean PMI fluctuated between 0.37 s.d. 0.012 and 0.38 s.d. 0.012. among the sixth age groups. One-way ANOVA statistical test revealed no significant of age on PMI. On the other hand gender variation has effect on PMI, since independent sample t-test disclosed that the difference between the male and female PMI means statistically significant. ANOVA test showed that the means of MR among age groups showed a negative correlation i.e. MR mean declined from 3.01 in 18-25 age groups to 2.7 in 55-65 age groups. In contrary, the gender showed no effect on MR according two sample t-test at p> 0.05. In regards with MCI, statistical analysis showed that it affected by age that is C1 was decreasing by age while C2 and C3 were increased by age. Using chi square test the result indicated that there is a significant difference among the different age group and the two genders in MCI readings. Conclusion: PMI was influenced significantly by age but minimally by the gender. MR is not affected by gender but has a negative correlation with age. MCI is affected by both age and gender


2020 ◽  
Vol 103 (6) ◽  
pp. 548-552

Objective: To predict the quality of anticoagulation control in patients with atrial fibrillation (AF) receiving warfarin in Thailand. Materials and Methods: The present study retrospectively recruited Thai AF patients receiving warfarin for three months or longer between June 2012 and December 2017 in Central Chest Institute of Thailand. The patients were classified into those with SAMe-TT₂R₂ of 2 or less, and 3 or more. The Chi-square test or Fisher’s exact test was used to compare the proportion of the patients with poor time in therapeutic range (TTR) between the two groups of SAMe-TT₂R₂ score. The discrimination performance of SAMe-TT₂R₂ score was demonstrated with c-statistics. Results: Ninety AF patients were enrolled. An average age was 69.89±10.04 years. Most patients were persistent AF. An average CHA₂DS₂-VASc, SAMe-TT₂R₂, and HAS-BLED score were 3.68±1.51, 3.26±0.88, and 1.98±0.85, respectively. The present study showed the increased proportion of AF patients with poor TTR with higher SAMe-TT₂R₂ score. The AF patients with SAMe-TT₂R₂ score of 3 or more had a larger proportion of patients with poor TTR than those with SAMe-TT₂R₂ score of 2 or less with statistical significance when TTR was below 70% (p=0.03) and 65% (p=0.04), respectively. The discrimination performance of SAMe-TT₂R₂ score was demonstrated with c-statistics of 0.60, 0.59, and 0.55 when TTR was below 70%, 65% and 60%, respectively. Conclusion: Thai AF patients receiving warfarin had a larger proportion of patients with poor TTR when the SAMe-TT₂R₂ score was higher. The score of 3 or more could predict poor quality of anticoagulation control in those patients. Keywords: Time in therapeutic range, Poor quality of anticoagulation control, Warfarin, SAMe-TT₂R₂, Labile INR


2008 ◽  
Vol 28 (3_suppl) ◽  
pp. 191-195 ◽  
Author(s):  
Chia-Te Liao ◽  
Chih-Chung Shiao ◽  
Jenq-Wen Huang ◽  
Kuan-Yu Hung ◽  
Hsueh-Fang Chuang ◽  
...  

⋄ Objective Loss of residual renal function (RRF) in peritoneal dialysis (PD) patients is a powerful predictor of mortality. The present study was conducted to determine the predictors of faster decline of RRF in PD patients in Taiwan. ⋄ Methods The study enrolled 270 patients starting PD between January 1996 and December 2005 in a single hospital in Taiwan. We calculated RRF as the mean of the sum of 24-hour urea and creatinine clearance. The slope of the decline of residual glomerular filtration rate (GFR) was the main outcome measure. Data on demographic, clinical, laboratory, and treatment parameters; episodes of peritonitis; and hypotensive events were analyzed by Student t-test, Mann–Whitney U-test, and chi-square, as appropriate. All variables with statistical significance were included in a multivariate linear regression model to select the best predictors ( p < 0.05) for faster decline of residual GFR. ⋄ Results All patients commencing PD during the study period were followed for 39.4 ± 24.0 months (median: 35.5 months). The average annual rate of decline of residual GFR was 1.377 ± 1.47 mL/min/m2. On multivariate analysis, presence of diabetes mellitus ( p < 0.001), higher baseline residual GFR ( p < 0.001), hypotensive events ( p = 0.001), use of diuretics ( p = 0.002), and episodes of peritonitis ( p = 0.043) independently predicted faster decline of residual GFR. Male sex, old age, larger body mass index, and presence of coronary artery disease or congestive heart failure were also risk factors on univariate analysis. ⋄ Conclusions Our results suggested that diabetes mellitus, higher baseline residual GFR, hypotensive events, and use of diuretics are independently associated with faster decline of residual GFR in PD patients in Taiwan.


2021 ◽  
pp. 194187442110070
Author(s):  
Felix Ejike Chukwudelunzu ◽  
Bart M Demaerschalk ◽  
Leonardo Fugoso ◽  
Emeka Amadi ◽  
Donn Dexter ◽  
...  

Background and purpose: In-hospital stroke-onset assessment and management present numerous challenges, especially in community hospitals. Comprehensive analysis of key stroke care metrics in community-based primary stroke centers is under-studied. Methods: Medical records were reviewed for patients admitted to a community hospital for non-cerebrovascular indications and for whom a stroke alert was activated between 2013 and 2019. Demographic, clinical, radiologic and laboratory information were collected for each incident stroke. Descriptive statistical analysis was employed. When applicable, Kruskal-Wallis and Chi-Square tests were used to compare median values and categorical data between pre-specified groups. Statistical significance was set at alpha = 0.05. Results: There were 192 patients with in-hospital stroke-alert activation; mean age (SD) was 71.0 years (15.0), 49.5% female. 51.6% (99/192) had in-hospital ischemic and hemorrhagic stroke. The most frequent mechanism of stroke was cardioembolism. Upon stroke activation, 45.8% had ischemic stroke while 40.1% had stroke mimics. Stroke team response time from activation was 26 minutes for all in-hospital activations. Intravenous thrombolysis was utilized in 8% of those with ischemic stroke; 3.4% were transferred for consideration of endovascular thrombectomy. In-hospital mortality was 17.7%, and the proportion of patients discharged to home was 34.4% for all activations. Conclusion: The in-hospital stroke mortality was high, and the proportions of patients who either received or were considered for acute intervention were low. Quality improvement targeting increased use of acute stroke intervention in eligible patients and reducing hospital mortality in this patient cohort is needed.


Author(s):  
Zhenzhen Rao ◽  
Junjie Hua ◽  
Ruotong Li ◽  
Yanhong Fu ◽  
Jie Li ◽  
...  

Recent changes in population-based prevalence for circulatory system diseases (CSDs) remain unreported either nationally or locally for China. Data were from the two-round health service household interview survey of Hunan Province, China, in 2013 and 2018. A Rao–Scott chi-square test was performed to examine prevalence differences across socio-demographic variables. The overall age-standardized prevalence of CSDs increased substantially between 2013 and 2018 for inhabitants aged 20 years and older (14.25% vs. 21.25%; adjusted odds ratio (OR) = 1.59, 95% CI: 1.24–2.04). Hypertensive disease was the most prevalent type of CSD, accounting for 87.24% and 83.83% of all CSDs in 2013 and in 2018, respectively. After controlling for other socio-demographic factors, the prevalence of CSDs was significantly higher in 2018 (adjusted OR = 1.40), urban residents (adjusted OR = 1.43), females (adjusted OR = 1.12) and older age groups (adjusted OR = 5.36 for 50–59 years, 9.51 for 60–69 years, 15.19 for 70–79 years, and 12.90 for 80 years and older) than in 2013, rural residents, males and the youngest age group (20–49 years). The recent increase in the overall age-standardized CSD prevalence and the large prevalence disparities across urban/rural residents, sex and age groups merit the attention of policymakers and researchers. Further prevention efforts are needed to curb the increasing tendency and to reduce the prevalence of disparities across socio-demographic groups.


Author(s):  
Kemar J Brown ◽  
Njambi Mathenge ◽  
Daniela Crousillat ◽  
Jaclyn Pagliaro ◽  
Connor Grady ◽  
...  

Abstract Background The coronavirus disease 2019 (COVID-19) pandemic has resulted in the rapid uptake of telemedicine (TM) for routine cardiovascular care. Objectives To examine the predictors of TM utilization among ambulatory cardiology patients during the COVID-19 pandemic. Methods In this single centre retrospective study, all ambulatory cardiovascular encounters occurring between March 16th - June 19th, 2020 were assessed. Baseline characteristics by visit type (in-person, TM-phone, TM-video) were compared using Chi-square and student t-tests, with statistical significance defined by p value &lt; 0.05. Multivariate logistic regression was used to explore the predictors of TM versus in-person care. Results 8446 patients (86% Non-Hispanic White, 42% female, median age 66.8 +/- 15.2 years) completed an ambulatory cardiovascular visit during the study period. TM-phone (n = 4,981, 61.5%) was the primary mode of ambulatory care followed by TM-video (n = 2693, 33.2%). Non-Hispanic Black race (OR 0.56; 95% CI: 0.35 - 0.94, p-value=0.02), Hispanic ethnicity (OR 0.53; 95% CI: 0.29 - 0.98, p = 0.04), public insurance (Medicaid OR 0.50; 95% CI:0.32 – 0.79, p = 0.003, Medicare OR 0.65; 95% CI: 0.47– 0.89, p = 0.009), zip-code linked median household income (MHI) of &lt;$75,000, age &gt;85 years, and patients with a diagnosis of heart failure were associated with reduced access to TM-video encounters and a higher likelihood of in-person care. Conclusions Significant disparities in TM-video access for ambulatory cardiovascular care exist among the elderly, lower income, as well as Black and Hispanic racial/ethnic groups.


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