scholarly journals Comparative Study between an Immediate Loading Protocol Using the Digital Workflow and a Conventional Protocol for Dental Implant Treatment: A Randomized Clinical Trial

2019 ◽  
Vol 8 (5) ◽  
pp. 622 ◽  
Author(s):  
Piyanut Rattanapanich ◽  
Weerapan Aunmeungtong ◽  
Pisaisit Chaijareenont ◽  
Pathawee Khongkhunthian
Keyword(s):  
Clinical Trial ◽  
Patient Satisfaction ◽  
Success Rate ◽  
Randomized Clinical Trial ◽  
Immediate Loading ◽  
Digital Workflow ◽  
Significant Difference ◽  
Bone Level ◽  
Marginal Bone Level ◽  
Implant Treatment

Background: The purposes of this randomized clinical trial study was to compare the immediate loading of dental implants while employing digital workflow and conventional implants in terms of the success rate, marginal bone level, and patient satisfaction. Methods: Fifty patients who had edentulous area on the mandibular premolar or molar area were included in the study. Twenty-five patients were assigned to immediate loading implant treatment using the digital technique and 25 patients were assigned to conventional loading implant treatment. In the first group, the patients were received digital impression (Cerec Omnicam, Dentsply Sirona®, York, PA, USA), designed, producing zirconia crown, and inserted on the same surgery day. The second group, after a healing period of three months, was received analog impression following conventional impression for the zirconia crown. Clinical outcome and radiographic bone level were evaluated after three, six, and 12 months. Patient satisfaction was measured at 12 months after inserting the implant. Results: There was no implants and protheses failure in both groups. The mean resonance frequency analysis values at the day of surgery were 78.26 ± 4.09 in immediate loading using the digital group (ILD) and 73.74 ± 5.14 in the conventional loading group (CL), respectively. Insertion torque values at the day of surgery were 36.60 ± 12.64 in ILD and 38.8 ± 12.19 CL, respectively. The marginal bone level in CL at three, six, and 12 months were 0.14 ± 0.28 mm, 0.18 ± 0.30 mm, and 0.17 ± 0.29 mm, respectively, while in ILD at three, six, and 12 months were 0.18 ± 0.33 mm and 0.16 ± 0.27 mm and 0.15 ± 0.31, respectively. There was no statistically significant difference between the two groups. Only one question in patient satisfaction’s questionnaire was “Now, can your dental implant and crown be used well?” had been significantly different in favor to the conventional group. Conclusion: Within the limitation of this study, it may be concluded that, after one-year follow up, there were no statistically significant differences between the immediate loading of dental implants employed from the digital workflow and conventional implant treatment technique in the success rate and marginal bone level. In patient satisfaction, there was only statistic significant difference in question related to implant prosthetic function in favor of the CL group, whereas the question concerning speaking, cleansing, price, and expectation displayed no difference.

scholarly journals The Effect of Eutectic Mixture of Local Anesthesia Cream (EMLA) on Satisfaction, Pain, and Nausea/Vomiting of Patients Undergoing Gastro-intestinal Endoscopy-A Randomized Clinical Trial Comparing EMLA Cream and Gel, Lidocaine Gel and Spray, and Placebo

2016 ◽  
Vol 9 (1) ◽  
pp. 273
Author(s):  
Jafar Nasiri ◽  
Amin Ahmadi ◽  
Forouzan Ganji
Keyword(s):  
Clinical Trial ◽  
Patient Satisfaction ◽  
Randomized Clinical Trial ◽  
Local Anesthesia ◽  
Eutectic Mixture ◽  
Double Blind ◽  
Patient Satisfaction Score ◽  
Emla Cream ◽  
Significant Difference ◽  
Lidocaine Gel

BACKGROUND & OBJECTIVES: Esophagogastroduodenoscopy is a valuable diagnostic method for the treatment of various diseases that has found a wonderful application in recent years. Yet, controlling patients’ pain and nausea is a fundamental factor to increase patient satisfaction, reduce patients’ discomfort, and increase the patient’s cooperation. Therefore, this study aimed to assess the efficacy of Eutectic Mixture of Local Anesthesia (EMLA) cream and gel, as a topical pharyngeal anesthetic on patients’ pharyngeal pain, nausea/vomiting, and satisfaction, in comparison with lidocaine gel and spray and placebo.METHODS: This double-blind randomized clinical trial was conducted to assess patient satisfaction, nausea/vomiting, throat and pharyngeal pain during and after endoscopy by different methods of local anesthesia. Thus, 150 patients were randomly divided into 5 groups of 30 receiving placebo, lidocaine gel, lidocaine spray, EMLA gel and cream 5 to 10 minutes before endoscopy. Then patient satisfaction (measured by GHAA-9 questionnaire), pain or discomfort in the throat, and nausea/vomiting were evaluated half an hour after endoscopy.RESULTS: Patient satisfaction score was not statistically different between the test groups (P>0.05), but the throat pain and discomfort and nausea/vomiting during and after endoscopy was statistically different between groups (P<0.05) and the lowest nausea/vomiting was in the group using EMLA cream.CONCLUSION: Different methods of throat anesthesia had no significant difference on patient satisfaction but EMLA cream and gel caused less nausea/vomiting than lidocaine gel or spray during and after endoscopy.

scholarly journals Overdentures Supported by Mini or Conventional Implants-effect on Patient Satisfaction and Bone Resorption Rates. A Randomized Clinical Trial

2021 ◽  
Vol 9 (D) ◽  
pp. 300-313
Author(s):  
Osama Ahmed Gaballa ◽  
Hamdy Abo El Fotouh Hamed ◽  
Ahmed Emad Fayyad ◽  
Mohamed Marwan Rahhal
Keyword(s):  
Clinical Trial ◽  
Patient Satisfaction ◽  
Randomized Clinical Trial ◽  
Base Line ◽  
Mini Implants ◽  
Significant Difference ◽  
Bone Expansion ◽  
The Difference ◽  
High Level ◽  
Bone Height

AIM: The aim of the study was to assess the difference between patient satisfaction and bone height changes of mini-implant supported overdentures in comparison with conventional implant after bone expansion technique. METHODS: This randomized clinical trial contains 36 edentulous participants with thin mandibular ridges randomly divided to receive 2 mini-implants, or 2 conventional implants after ridge splitting, both treatments were done in the inter-forminal area of the anterior mandible. Then, the patients received mandibular overdentures with ball and socket attachments. At base line, after 6 and 12 months of loading the implants, patients’ satisfaction was evaluated using visual analog scale, in addition to bone height changes using Soredex DIGORA Optime Classic software. RESULTS: There was statistically significant difference in the overall satisfaction between the mini-implants and the conventional implants group; the amount of bone height changes in the mini-implant group was statistically significant less than the conventional implant group at base line, 6 and 12 months. CONCLUSION: Treatment with two mini-implants provides high level of satisfaction and less bone height changes in a follow-up period of 12 months in comparison to conventional implants after ridge expansion.

Prospective Randomized Clinical Trial on the Survival of Lithium Disilicate Posterior Partial Crowns Bonded Using Immediate or Delayed Dentin Sealing: Short-term Results on Tooth Sensitivity and Patient Satisfaction

2019 ◽  
Vol 44 (5) ◽  
pp. E212-E222 ◽  
Author(s):  
C van den Breemer ◽  
MMM Gresnigt ◽  
M Özcan ◽  
W Kerdijk ◽  
MS Cune
Keyword(s):  
Clinical Trial ◽  
Patient Satisfaction ◽  
Randomized Clinical Trial ◽  
Lithium Disilicate ◽  
Tooth Sensitivity ◽  
Prospective Randomized Clinical Trial ◽  
Time Points ◽  
Significant Difference ◽  
Molar Teeth ◽  
Ceramic Restorations

SUMMARY This prospective randomized clinical trial evaluated tooth sensitivity and patient satisfaction after the provision of partial ceramic restorations bonded using immediate (IDS) or delayed dentin sealing (DDS) on vital molar teeth through a within-subject comparison study. Between December 2013 and May 2016, a total of 30 patients (13 women, 17 men; mean age, 54 years old) received two lithium disilicate ceramic (IPS-e.max press, Ivoclar Vivadent) partial restorations on vital first or second molar teeth (N=60). The two teeth randomly received either IDS (test group, n=30) or DDS (control group, n=30). Partial preparations were performed on all teeth and directly after tooth preparation. IDS was achieved using self-etch adhesive (Clearfil SE Primer and Adhesive, Kuraray) followed by the application of flowable resin (Clearfil Majesty Flow, Kuraray). Partial ceramic restorations were bonded (Variolink Ultra, Ivoclar Vivadent) two weeks after preparation. The teeth were evaluated preoperatively and at one week, three months, and 12 months postoperatively using a cold test and a questionnaire for perceived tooth sensitivity. Patient satisfaction was evaluated using a visual analog scale (VAS). Data were analyzed using McNemar, chi-squared, and Wilcoxon signed rank tests (α=0.01). There was no significant difference in patient-reported tooth sensitivity between the preoperative phase and all other time points (p&gt;0.01). There was also no significant difference between IDS and DDS (p&gt;0.01) for all items on the questionnaire. VAS scores did not differ significantly between the IDS and DDS groups for all items in the questionnaire at all time points (p&gt;0.01). No tooth sensitivity change was noticed with the application of partial ceramic indirect restorations. This clinical study could not confirm that IDS is more advantageous than DDS in terms of tooth sensitivity and patient satisfaction at 1 year of clinical service of partial ceramic restorations.

scholarly journals Oral Versus Intramuscular Ondansetron for Reducing Vomiting in Children with Acute Gastroenteritis: A Single-Blind Randomized Clinical Trial

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Kambiz Eftekhari ◽  
Sahar Mohammadpour ◽  
Elham Shahgholi ◽  
Hosein Shabani Mirzaee ◽  
Mohsen Vigeh ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Success Rate ◽  
Randomized Clinical Trial ◽  
Drug Administration ◽  
Acute Gastroenteritis ◽  
Intramuscular Injection ◽  
High Rate ◽  
Significant Difference ◽  
Single Blind ◽  
Oral Ondansetron

Background: Acute gastroenteritis is one of the most common diseases in children with a high rate of nausea and vomiting. Drugs such as ondansetron are used to treat vomiting. Objectives: The aim of the study was to compare the success rate of oral vs intramuscular ondansetron to reduce vomiting in children with acute gastroenteritis. Methods: A single-blind randomized clinical trial study was conducted on 100 children with acute gastroenteritis. Two groups of patients were created; one group received an intramuscular injection of ondansetron and the other received oral ondansetron. The vomiting rate, hospitalization, and side effects were evaluated 30 minutes, 4, and 48 hours after drug administration. Results: Fifty-nine (59%) boys with a mean age between 3.07 ± 2.20 years were included. There were no significant differences between the groups in terms of age, weight, and rate of vomiting before the treatment was launched. No significant difference between the drug administration route and the outcome of vomiting during the first half, 4, and 48 hours after receiving the drug was found either. Conclusions: The study showed that the success rate of oral ondansetron did not vary significantly compared to intramuscular injection in terms of reducing the vomiting rate in children with acute gastroenteritis.

A 7-year prospective radiographic evaluation of marginal bone level around two different implant systems: a randomized clinical trial

2014 ◽  
Vol 26 (11) ◽  
pp. 1244-1249 ◽  
Author(s):  
Doris Burtscher ◽  
Burkhard Norer ◽  
Daniel Dalla Torre ◽  
Ulrike Beier ◽  
Katharina Schubert ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Radiographic Evaluation ◽  
Bone Level ◽  
Marginal Bone Level

scholarly journals Comparing the efficacy and side-effects of PDLASTA® (Pegfilgrastim) with PDGRASTIM® (Filgrastim) in breast cancer patients: a non-inferiority randomized clinical trial

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Safa Najafi ◽  
Maryam Ansari ◽  
Vahid Kaveh ◽  
Shahpar Haghighat
Keyword(s):  
Breast Cancer ◽  
Clinical Trial ◽  
Single Dose ◽  
Side Effects ◽  
Randomized Clinical Trial ◽  
Cancer Patients ◽  
Injection Site Reaction ◽  
Study Groups ◽  
Breast Cancer Patients ◽  
Significant Difference

Abstract Background The objective of this study was to compare the efficacy and side effects of a single dose (Pegfilgrastim or PDL) or repeated six daily injections (Filgrastim or PDG) during chemotherapy courses in breast cancer patients in a non-inferiority clinical trial. Methods In this randomized clinical trial, 80 patients were recruited and allocated randomly to two equal arms. In one group, a single subcutaneous dose of PDL was injected the day after receiving the chemotherapy regimen in each cycle. The second arm received a subcutaneous injection of PDG for six consecutive days in each cycle of treatment. The side effects of GCF treatment and its effect on blood parameters were compared in each cycle and during eight cycles of chemotherapy. Results Hematologic parameters showed no significant differences in any of the treatment courses between the two study groups. The comparison of WBC (p = 0.527), Hgb (p = 0.075), Platelet (p = 0.819), Neutrophil (p = 0.575), Lymphocyte (p = 705) and ANC (p = 0.675) changes during the eight courses of treatment also revealed no statistically significant difference between the two study groups. Side effects including headache, injection site reaction and muscle pain had a lower frequency in patients receiving PDL drugs. Conclusion It seems that PDL is non-inferior in efficacy and also less toxic than PDG. Since PDL can be administered in a single dose and is also less costly, it can be regarded as a cost-effective drug for the treatment of chemotherapy-induced neutropenia. Trial registration IRCT20190504043465N1, May 2019.

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