scholarly journals Areas of Interest and Attitudes towards the Pharmacological Treatment of Attention Deficit Hyperactivity Disorder: Thematic and Quantitative Analysis Using Twitter

2021 ◽  
Vol 10 (12) ◽  
pp. 2668
Author(s):  
Miguel Angel Alvarez-Mon ◽  
Laura de Anta ◽  
Maria Llavero-Valero ◽  
Guillermo Lahera ◽  
Miguel A. Ortega ◽  
...  

We focused on tweets containing hashtags related to ADHD pharmacotherapy between 20 September and 31 October 2019. Tweets were classified as to whether they described medical issues or not. Tweets with medical content were classified according to the topic they referred to: side effects, efficacy, or adherence. Furthermore, we classified any links included within a tweet as either scientific or non-scientific. We created a dataset of 6568 tweets: 4949 (75.4%) related to stimulants, 605 (9.2%) to non-stimulants and 1014 (15.4%) to alpha-2 agonists. Next, we manually analyzed 1810 tweets. In the end, 481 (48%) of the tweets in the stimulant group, 218 (71.9%) in the non-stimulant group and 162 (31.9%) in the alpha agonist group were considered classifiable. Stimulants accumulated the majority of tweets. Notably, the content that generated the highest frequency of tweets was that related to treatment efficacy, with alpha-2 agonist-related tweets accumulating the highest proportion of positive consideration. We found the highest percentages of tweets with scientific links in those posts related to alpha-2 agonists. Stimulant-related tweets obtained the highest proportion of likes and were the most disseminated within the Twitter community. Understanding the public view of these medications is necessary to design promotional strategies aimed at the appropriate population.

2021 ◽  
Author(s):  
Miguel Angel Alvarez-Mon ◽  
Laura de Anta ◽  
Maria Llavero-Valero ◽  
Miguel Angel Ortega ◽  
Guillermo Lahera ◽  
...  

BACKGROUND The treatment of ADHD is complex and may involve behavioral, psychological and educational interventions, as well as medication. Different pharmacological treatments have shown efficacy in reducing ADHD symptoms and improving daily functioning. Analysis of tweets has become a tool for understanding perceptions by the general population on health issues. OBJECTIVE Investigate the gap existing between its extensive scientific support and the lack of widespread prescription and adherence. We hypothesize that such a discrepancy may be influenced by a lack of knowledge of the positive effects among the population. Thus, we find it interesting and worthwhile to assess opinions and social interest on ADHD pharmacotherapy in Twitter. METHODS In this observational quantitative and qualitative study we focused on tweets containing hashtags related to ADHD pharmacotherapy between September 20th and October 31st 2019. Tweets were first classified as to whether they described medical issues or not. Tweets with medical content were classified according to the topic they referred to: side effects, efficacy, or adherence. Furthermore, we classified any links included within a tweet as either scientific or non-scientific. RESULTS We collected a total of 118,388 tweets, 111,820 of which were excluded according to the criteria of the study. This process led to the creation of a more concise dataset of 6,568 tweets: 4,949 (75.4%) related to stimulants, 605 (9.2%) to non-stimulants and 1,014 (15.4%) to alpha-2-agonists. Next, we manually analyzed 1,810 tweets: 1,000 tweets related to stimulants, 303 to non-stimulants and 507 to alpha-agonists. In the end, 481 (48%) of the tweets in the stimulant group, 218 (71.9%) in the non-stimulant group and 162 (31.9%) in the alpha-agonist group were considered classifiable according to the codebook. Stimulants accumulated the majority of tweets. Notably, the content that generated the highest frequency of tweets was that related to treatment efficacy, with alpha-2-agonists related tweets accumulating the highest proportion of positive consideration. We found the highest percentages of tweets with scientific links in those posts related alpha-2-agonists. CONCLUSIONS Stimulants related tweets obtained the highest probability of likes and were the most disseminated within the Twitter community. Understanding the public view of these medications is necessary to design promotional strategies aimed at the appropriate population.


2020 ◽  
Author(s):  
Miguel Alvarez de Mon ◽  
Maria Llavero-Valero ◽  
Angel Asunsolo del Barco ◽  
Cristina Zaragozá ◽  
Miguel Angel Ortega ◽  
...  

BACKGROUND Twitter is an appropriate arena to assess the social consideration and attitudes towards anti-obesity drugs. OBJECTIVE To investigate the content and key metrics of tweets referring to anti-obesity drugs. METHODS In this observational quantitative and qualitative study, we focused on tweets containing hashtags related to anti-obesity drugs between September 20th and October 31st 2019. Tweets were first classified as to whether they described medical issues or not. Tweets with medical content were classified according to the topic they referred to: side effects, efficacy, or adherence. We additionally rated it as positive or negative. Furthermore, we classified any links included within a tweet as either scientific or non-scientific. Finally, the number of retweets generated as well as the dissemination and sentiment score obtained by the anti-obesity drugs analyzed were also measured. RESULTS We analyzed a total of 2,045 tweets, 945 of which were excluded according to the criteria of the study. Finally, 320 out of the 1,100 remaining tweets were also excluded because their content, although related to drugs for obesity treatment, did not address the efficacy and side effects of said medication, nor to adherence. Liraglutide and semaglutide accumulated the majority of tweets (87.4%). Notably, the content that generated the highest frequency of tweets was that related to treatment efficacy, with liraglutide, semaglutide and lorcaserin related tweets accumulating the highest proportion of positive consideration. We found the highest percentages of tweets with scientific links in those posts related to liraglutide and semaglutide. Semaglutide related tweets obtained the highest probability of likes and were the most disseminated within the Twitter community. CONCLUSIONS Understanding the public view of these medications is necessary to design promotional strategies aimed at the appropriate population. Participation of researchers and health providers in related conversations and debates might create a collective opinion based on scientific data.


2007 ◽  
Vol 4 (3) ◽  
pp. 71-73
Author(s):  
Sahbal Aras ◽  
Semih Semin

Recently, the use of psychostimulant medication in children with symptoms of attention-deficit hyperactivity disorder (ADHD) has been subject to extensive debate. The problems faced while assessing and diagnosing ADHD, unnecessary prescribing of psychostimulants, the possible side-effects of psychostimulants on the developing brain, the risk of drug dependency, and the risk of stigmatising children through medicalisation of normal life events are considered among the principal objections to the use of psychostimulant medications. On the other hand, what also need to be taken into account are the increasing evidence on the genetic, biochemical and diagnostic validity of the disorder, the data showing the therapeutic effects of psychostimulants and the rarity of the above-mentioned side-effects, as well as the ethical problems created by insufficient treatment of children because of the concerns of parents. A critical evaluation of these conflicting opinions by mental health professionals might contribute to the application of ethical principles. While making this kind of evaluation, it is important to pay regard to the specific sociocultural features of the country, as well as the prevailing worldwide discussion.


2018 ◽  
pp. 11-15
Author(s):  
Tamoghna Bandyopadhyay ◽  
Aratrika Sen

Attention - Deficit Hyperactivity Disorder (ADHD) is one of the most common childhood behavioral disorders diagnosed in the psychiatry outdoor setting, affecting 5-7% of school - aged children[1]. It is a neuro - developmental disorder that runs a chronic course and causes significant impairments across various domains of day to day functioning. The symptoms of ADHD are divided into two predominant categories: inattention and hyperactivity/impulsivity. Inattention is divided intwo subtypes i.e. focused and sustained/ Executive dysfunction.


2011 ◽  
Vol 3 ◽  
pp. CMT.S6615
Author(s):  
Caroline Bodey

Attention deficit hyperactivity disorder (ADHD) is a common condition and important for the affected individual, their family and society. It manifests with pervasive symptoms of hyperactivity, impulsivity and inattention. In many children with ADHD these symptoms persist into adolescence and adulthood. Drug treatment with psychostimulants, including methylphenidate, is an important part of a comprehensive treatment plan for children with severe ADHD that includes psychosocial, behavioural and educational advice and interventions. Methylphenidate is a central nervous system stimulant, whose mechanism of action is thought to be due to an increase in catecholamines in areas of the brain concerned with motivation and reward. Methylphendiate is available in short acting (immediate release) and longer acting (modified release) forms. Pharmacotherapy for ADHD is in three stages: initiation, maintenance and termination. The efficacy of methylphenidate in terms of reducing core symptoms is 70% as compared to placebo. This efficacy is maintained for at least 24 months. Methylphenidate generally has a favourable side effect profile. The most significant side effects include appetite suppression with an initial deceleration in height velocity, cardiovascular side effects that are not clinically significant in children with no adverse cardiac history, and tics. Methylphenidate is generally well tolerated and liked by children and adolescents with ADHD, who appreciate the benefits that medication has on their behaviour.


2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Juan Carlos Corona

Parkinson’s disease (PD) is the second most common neurodegenerative disorder with an unknown aetiology. The pathogenic mechanisms include oxidative stress, mitochondrial dysfunction, protein dysfunction, inflammation, autophagy, apoptosis, and abnormal deposition of α-synuclein. Currently, the existing pharmacological treatments for PD cannot improve fundamentally the degenerative process of dopaminergic neurons and have numerous side effects. On the other hand, attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood and is characterised by hyperactivity, impulsivity, and inattention. The aetiology of ADHD remains unknown, although it has been suggested that its pathophysiology involves abnormalities in several brain regions, disturbances of the catecholaminergic pathway, and oxidative stress. Psychostimulants and nonpsychostimulants are the drugs prescribed for the treatment of ADHD; however, they have been associated with increased risk of substance use and have several side effects. Today, there are very few tools available to prevent or to counteract the progression of such neurological disorders. Thus, therapeutic approaches with high efficiency and fewer side effects are needed. This review presents a brief overview of the two neurological disorders and their current treatments, followed by a discussion of the natural compounds which have been studied as therapeutic agents and the mechanisms underlying the beneficial effects, in particular, the decrease in oxidative stress.


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