scholarly journals Management of Dyspepsia and Gastroparesis in Patients with Diabetes. A Clinical Point of View in the Year 2021

2021 ◽  
Vol 10 (6) ◽  
pp. 1313
Author(s):  
Silvia Bonetto ◽  
Gabriella Gruden ◽  
Guglielmo Beccuti ◽  
Arianna Ferro ◽  
Giorgio Maria Saracco ◽  
...  
Keyword(s):  
Gastrointestinal Symptoms ◽  
Neurological Complications ◽  
Pharmacological Therapy ◽  
Point Of View ◽  
Public Health Burden ◽  
Wide Range ◽  
Patients With Diabetes ◽  
Upper Gastrointestinal Symptoms ◽  
Cells Of Cajal ◽  
Diabetic Enteropathy

Diabetes mellitus is a widespread disease, and represents an important public health burden worldwide. Together with cardiovascular, renal and neurological complications, many patients with diabetes present with gastrointestinal symptoms, which configure the so-called diabetic enteropathy. In this review, we will focus on upper gastrointestinal symptoms in patients with diabetes, with particular attention to dyspepsia and diabetic gastroparesis (DG). These two clinical entities share similar pathogenetic mechanisms, which include autonomic neuropathy, alterations in enteric nervous system and histological abnormalities, such as interstitial cells of Cajal depletion. Moreover, the differential diagnosis may be challenging because of overlapping clinical features. Delayed gastric emptying should be documented to differentiate between DG and dyspepsia and it can be assessed through radioactive or non-radioactive methods. The clinical management of dyspepsia includes a wide range of different approaches, above all Helicobacter pylori test and treat. As regards DG treatment, a central role is played by dietary modification and glucose control and the first-line pharmacological therapy is represented by the use of prokinetics. A minority of patients with DG refractory to medical treatment may require more invasive therapeutic approaches, including supplemental nutrition, gastric electric stimulation, pyloromyotomy and gastrectomy.

scholarly journals Gastroparesis: Prevalence, Clinical Significance and Treatment

2001 ◽  
Vol 15 (12) ◽  
pp. 805-813 ◽  
Author(s):  
Michael Horowitz ◽  
Yu-Chung Su ◽  
Christopher K Rayner ◽  
Karen L Jones
Keyword(s):  
Diabetes Mellitus ◽  
Gastric Emptying ◽  
Blood Glucose Control ◽  
Gastrointestinal Symptoms ◽  
Oral Drug ◽  
Patients With Diabetes ◽  
Upper Gastrointestinal Symptoms ◽  
Potential Impact ◽  
Direct Outcome

The application of novel techniques to quantify gastric motor function and gastric emptying has yielded important insights into the prevalence, pathogenesis and clinical sequelae of gastroparesis. Both acute and chronic gastroparesis occur frequently; gastric emptying of solids is delayed in 30% to 50% of patients with diabetes mellitus, functional dyspepsia and gastroesophageal reflux disease. While many patients with gastroparesis experience upper gastrointestinal symptoms that adversely affect quality of life, the concept that symptoms are inevitably the direct outcome of delay in gastric emptying is now recognized to be overly simplistic. In contrast, the potential impact of gastroparesis on oral drug absorption and blood glucose control in patients with diabetes mellitus has probably been underestimated. While the use of prokinetic drugs (cisapride, domperidone, metoclopramide and erythromycin) forms the mainstay of therapy in symptomatic patients with gastroparesis, a number of novel pharmacological therapies are being evaluated, and preliminary studies using gastric pacing show promise.

A longitudinal study of gastric emptying and upper gastrointestinal symptoms in patients with diabetes mellitus

2002 ◽  
Vol 113 (6) ◽  
pp. 449-455 ◽  
Author(s):  
Karen L Jones ◽  
Antonietta Russo ◽  
Melanie K Berry ◽  
Julie E Stevens ◽  
Judith M Wishart ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Longitudinal Study ◽  
Gastric Emptying ◽  
Gastrointestinal Symptoms ◽  
Patients With Diabetes ◽  
Upper Gastrointestinal Symptoms ◽  
Upper Gastrointestinal

Colorimetric research of self-luminous objects in software and hardware environments by the method of multidimensional scales implementation

2020 ◽  
pp. 43-50
Author(s):  
Yauheniya N. Saukova
Keyword(s):  
Metrological Traceability ◽  
Point Of View ◽  
Intermediate Precision ◽  
Technical Vision ◽  
Wide Range ◽  
Chromaticity Coordinates ◽  
Unity Of Measurements ◽  
Software And Hardware ◽  
Luminous Objects ◽  
Reference Samples

It is shown that the issues of metrological traceability for extended self-luminous objects with a wide range of brightness have not yet been resolved, since the rank scales of embedded systems are used for processing digital images. For such scales, there is no “fixed” unit, which does not allow you to get reliable results and ensure the unity of measurements. An experiment is described to evaluate the accuracy of determining the intensity (coordinates) of the color of self-luminous objects. In terms of repeatability and intermediate precision compared to the reference measurement method, the color and chromaticity coordinates of self-luminous objects (reference samples) were determined by their multiple digital registration using technical vision systems. The possibilities of the developed methodology for colorimetric studies in hardware and software environments from the point of view of constructing a multidimensional conditional scale are determined.

COMBINATORIAL POLYNOMIALLY COMPUTABLE CHARACTERISTICS OF SUBSTITUTIONS AND THEIR PROPERTIES

2020 ◽  
Vol 7 (2) ◽  
pp. 34-41
Author(s):  
VLADIMIR NIKONOV ◽  
◽  
ANTON ZOBOV ◽  
Keyword(s):  
Mathematical Expectation ◽  
Point Of View ◽  
Small Range ◽  
Computational Point ◽  
Wide Range ◽  
Bijective Function ◽  
The Difference ◽  
Element Base ◽  
Selection Of

The construction and selection of a suitable bijective function, that is, substitution, is now becoming an important applied task, particularly for building block encryption systems. Many articles have suggested using different approaches to determining the quality of substitution, but most of them are highly computationally complex. The solution of this problem will significantly expand the range of methods for constructing and analyzing scheme in information protection systems. The purpose of research is to find easily measurable characteristics of substitutions, allowing to evaluate their quality, and also measures of the proximity of a particular substitutions to a random one, or its distance from it. For this purpose, several characteristics were proposed in this work: difference and polynomial, and their mathematical expectation was found, as well as variance for the difference characteristic. This allows us to make a conclusion about its quality by comparing the result of calculating the characteristic for a particular substitution with the calculated mathematical expectation. From a computational point of view, the thesises of the article are of exceptional interest due to the simplicity of the algorithm for quantifying the quality of bijective function substitutions. By its nature, the operation of calculating the difference characteristic carries out a simple summation of integer terms in a fixed and small range. Such an operation, both in the modern and in the prospective element base, is embedded in the logic of a wide range of functional elements, especially when implementing computational actions in the optical range, or on other carriers related to the field of nanotechnology.

Academy Journal No.3(15), 2019/ Chief Editors Susan Belih & Jaak Järv /OEAPS Inc.(Open European Academy of Public Sciences) & Estonian Academy of Sciences. Tallinn, Estonia. 09.03.2019: OEAPS Inc., 2019. - 88 P. ISBN: 9781797440507 ISSN 1736-7530 (electronic)

2019 ◽  
Author(s):  
Inc. OEAPS
Keyword(s):  
Service Sector ◽  
Point Of View ◽  
Scientific Quality ◽  
Final Decision ◽  
Research Subjects ◽  
Wide Range ◽  
Peer Reviewers ◽  
Verification Process ◽  
Scientific Research Articles ◽  
Monthly Journal

"Academy Journal" is an international, peer-reviewed monthly journal. It is devoted to the publication of original scientific research articles dealing with various academic disciplines.Articles that may be of interest to a wide range of researchers are welcome, and not limited to those who work on specific research subjects."Academy Journal" has an open archive, according to which published articles are available immediately after publication, excluding embargoes.Expert reviewThere is one blind verification process in the journal. All articles will be initially evaluated by the editor for compliance with the journal. Manuscripts that are considered appropriate are then usually sent to at least two independent peer reviewers to assess the scientific quality of the article. The editor is responsible for the final decision on whether to accept or reject the article. The editor's decision is final.The main criterion used in assessing the manuscript submitted to the journal is: uniqueness or innovation in the work from the point of view of the methodology being developed and / or its application to a problem of particular importance in the public sector or service sector and / or the setting in which the efforts, for example, in the developing region of the world. That is, the very model / methodology, application and context of problems, at least one of them must be unique and important.Additional criteria considered in the consideration of the submitted document are its accuracy, organization / presentation (ie logical flow) and recording quality.

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