scholarly journals The Acute Effect of Exercise on Arterial Stiffness in Healthy Subjects: A Meta-Analysis

2021 ◽  
Vol 10 (2) ◽  
pp. 291
Author(s):  
Alicia Saz-Lara ◽  
Iván Cavero-Redondo ◽  
Celia Álvarez-Bueno ◽  
Blanca Notario-Pacheco ◽  
Marta Carolina Ruiz-Grao ◽  
...  

Arterial stiffness has been shown to be a subclinical marker associated with cardiovascular disease. Meanwhile, long-term exercise has been demonstrated to reduce arterial stiffness, providing a decrease in cardiovascular risk. However, the acute effect of exercise on arterial stiffness is unclear. This systematic review and meta-analysis aimed to assess the acute effect of exercise interventions on arterial stiffness in healthy adults. We searched the Cochrane Central Register of Controlled Trials, MEDLINE (via Pubmed), Scopus, and Web of Science databases, from their inception to 30 June 2020. A meta-analysis was performed to evaluate the acute effect of exercise on arterial stiffness using random-effects models to calculate pooled effect size estimates and their corresponding 95% CI. Pulse wave velocity was measured as an arterial stiffness index. The 30 studies included in the meta-analysis showed that pulse wave velocity was not modified immediately after exercise (0 min post) (ES: 0.02; 95% CI: −0.22, 0.26), but subsequently decreased 30 min after exercise (ES: −0.27; 95% CI: −0.43, −0.12). Thereafter, pulse wave velocity increased to its initial value 24 h after exercise (ES: −0.07; 95% CI: −0.21, 0.07). Our results show that, although there is a significant reduction in pulse wave velocity 30 min after exercise, the levels of arterial stiffness return to their basal levels after 24 h. These findings could imply that, in order to achieve improvements in pulse wave velocity, exercise should be performed on a daily basis.

2019 ◽  
Vol 15 (6) ◽  
pp. 1365-1374 ◽  
Author(s):  
Željko Reiner ◽  
Luis Simental-Mendía ◽  
Massimiliano Ruscica ◽  
Niki Katsiki ◽  
Maciej Banach ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Juan Torrado ◽  
Daniel Bia ◽  
Yanina Zócalo ◽  
Ignacio Farro ◽  
Federico Farro ◽  
...  

Carotid-to-radial pulse wave velocity (PWVcr) has been proposed to evaluate endothelial function. However, the measurement ofPWVcris not without limitations. A new simple approach could have wide application.Stiffness index(SI) is obtained by analysis of the peripheral pulse wave and gives reproducible information about stiffness of large arteries. This study assessed the effects of hyperemia on SI and compared it withPWVcrin 14 healthy subjects. Both were measured at rest and during 8 minutes after ischemia. SI temporal course was determined. At 1 minute, SI andPWVcrdecreased (5.58±0.24to5.34±0.23 m/s,P<0.05;7.8±1.0to7.2±0.9 m/s;P<0.05, resp.). SI was positively related toPWVcrin baseline (r=0.62,P<0.05), at 1 minute (r=0.79,P<0.05), and during the whole experimental session (r=0.52,P<0.05).Conclusion. Hyperemia significantly decreases SI in healthy subjects. SI was related toPWVcrand could be used to facilitate the evaluation of hyperemia-related changes in arterial stiffness.


2020 ◽  
Vol 9 (7) ◽  
pp. 2080
Author(s):  
Irene Sequí-Domínguez ◽  
Iván Cavero-Redondo ◽  
Celia Álvarez-Bueno ◽  
Diana P Pozuelo-Carrascosa ◽  
Sergio Nuñez de Arenas-Arroyo ◽  
...  

Increased arterial stiffness has been associated with an increased risk of developing cardiovascular diseases and all-cause mortality. Pulse wave velocity (PWV) is an innovative and affordable measurement of arterial stiffness which may be an accessible tool to estimate mortality risk; however, no meta-analysis has estimated its predictive performance for cardiovascular and all-cause mortality. Moreover, reference values for PWV have only been established by consensus for healthy populations. The aim of this review was to estimate PWV and especially carotid femoral PWV performance predicting cardiovascular and all-cause mortality as well as comparing the resulting cfPWV thresholds with already established values in order to increase its validity. Original studies measuring PWV thresholds and its association with cardiovascular and all-cause mortality were systematically searched. The DerSimonian and Laird method was used to compute pooled estimates of diagnostic odds ratio (dOR), and overall test performances were summarized in hierarchical summary receiver operating characteristic curves (HSROC). Six studies were included in the meta-analysis. The pooled dOR values for the predictive performance of cfPWV were 11.23 (95 % CI, 7.29–1.29) for cardiovascular mortality and 6.52 (95% CI, 4.03–10.55) for all-cause mortality. The area under the HSROC curve for cfPWV was 0.75 (95% CI, 0.69–0.81) for cardiovascular mortality and 0.78 (95% CI, 0.74–0.83) for all-cause mortality, where the closest cut-off point to the summary point was 10.7 and 11.5, respectively. This systematic review and meta-analysis demonstrates that cfPWV is a useful and accurate cardiovascular mortality predictor and that its previously estimated reference values for estimating risk may be used in high-risk populations.


2021 ◽  
Author(s):  
Tannaz Jamialahmadi ◽  
Željko Reiner ◽  
Mona Alidadi ◽  
Matthew Kroh ◽  
Luis E. Simental-Mendia ◽  
...  

Hypertension ◽  
2016 ◽  
Vol 68 (suppl_1) ◽  
Author(s):  
Sikarin Upala ◽  
Anawin Sanguankeo

Background: Previous studies have shown inconclusive effects of target organ damage from white-coat hypertension (WCHT). Arterial stiffness is involved in the atherosclerotic processes in the setting of sustained hypertension. This meta-analysis aimed to compare arterial stiffness in subjects with diagnosis of WCHT to subjects with normotension (NT) and SHT. Methods: A comprehensive search of the databases of the MEDLINE and EMBASE was performed from inception through May 2016. The inclusion criterion was the observational studies’ assessment of the association between WCHT and NT or SHT in adult subjects. European Society of Hypertension practice guidelines for ambulatory blood pressure (BP) monitoring was used to define WCHT (office BP≥140/90mmHg and daytime BP <135/85mmHg), and SHT (office BP≥140/90mmHg and daytime BP≥135/85mmHg). Aortic stiffness was assessed using Carotid-femoral pulse wave velocity (PWV) measurements. Pooled mean difference (MD) of PWV and 95% confidence interval (CI) were calculated using a random-effect, generic inverse variance method. Results: Data were extracted from 4 observational studies involving 2,413 subjects. PWV is not different in patients with WCHT compared with SHT (pooled MD= -0.25 m/sec; 95% CI, -0.81 to 0.30; P-value=0.37, I 2 =74%). PWV in WCHT is also not different when compared with PWV in NT (MD= 0.86 m/sec; 95% CI, -0.30 to 2.03; P-value=0.15, I 2 =97%). Conclusion: In a meta-analysis, we observe that arterial stiffness measured by pulse wave velocity is not different in patients with white-coat hypertension when compared with sustained hypertension or normotension.


2010 ◽  
Vol 33 (12) ◽  
pp. 1272-1277 ◽  
Author(s):  
George S Stergiou ◽  
Anastasios Kollias ◽  
Periklis P Giovas ◽  
John Papagiannis ◽  
Leonidas G Roussias

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