scholarly journals One Pot Synthesis of Large Gold Nanoparticles with Triple Functional Ferrocene Ligands

2021 ◽  
Vol 22 (5) ◽  
pp. 2328
Author(s):  
Shenqing Wang ◽  
Fang Liu ◽  
Yin Liu ◽  
Hongyu Zhou ◽  
Bing Yan
Keyword(s):  
Gold Nanoparticles ◽  
Sodium Borohydride ◽  
Sodium Citrate ◽  
Reducing Agent ◽  
Lower Yield ◽  
One Pot ◽  
Surface Ligands ◽  
Synthesis Of Nanoparticles ◽  
Irregular Shapes

In biomedical, toxicological, and optoelectronic applications, the size of nanoparticles is one of the decisive factors. Therefore, synthesis of nanoparticles with controlled sizes is required. The current methods for synthesis of larger gold nanoparticles (GNPs, ~200 nm) are complex and tedious, producing nanoparticles with a lower yield and more irregular shapes. Using ferrocene as a primary reducing agent and stabilizer, sodium citrate as a dispersant, and sodium borohydride as an accessory reducing agent, GNPs of 200 nm were synthesized in a one pot reaction. Besides the roles of reducing agent and GNP stabilizer, ferrocene also served a role of quantitative marker for ligand loading, allowing an accurate determinate of surface ligands.

scholarly journals Facile and One Pot Synthesis of Gold Nanoparticles Using Tetraphenylborate and Polyvinylpyrrolidone for Selective Colorimetric Detection of Mercury Ions in Aqueous Medium

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Sidhureddy Boopathi ◽  
Shanmugam Senthilkumar ◽  
Kanala Lakshminarasimha Phani
Keyword(s):  
Gold Nanoparticles ◽  
Alkaline Medium ◽  
Color Change ◽  
Colorimetric Detection ◽  
Spherical Shape ◽  
Reducing Agent ◽  
Nanoparticle Dispersion ◽  
Mercury Ions ◽  
One Pot ◽  
Resonance Band

In this work, we reported for the first time, a facile and one step synthesis of gold nanoparticles from HAuCl4, employing tetraphenylborate as the reducing agent. The synthesis is not only facile but also yields “dumb-bell-shaped”particles. This shape appears to arise from a possible emulsion of the products of oxidation/decomposition of tetraphenylborate by HAuCl4, surrounding the particle. The size and shape of the AuNPs were characterized by Transmission electron microscopy (TEM) and UV-visible Spectroscopy. Interestingly, the addition of polyvinylpyrrolidone (PVP) during the synthesis was found to enhance the stability of the nanoparticle dispersion. The particles synthesized under these conditions assume “spherical” shape with the appearance of only transverse surface plasmon resonance band. The highlight of the observations is that the gold nanoparticles synthesized using tetraphenylborate as reducing agent and PVP as stabilizer are highly stable in alkaline medium, in contrast to the synthesis wherein borohydride is used as reducing agent. The AuNPs synthesized using tetraphenylborate and PVP show their mercury sensing behavior only in the alkaline medium. The color of the nanoparticle dispersion undergoes distinct color change from pink to blue with the addition of mercury ions. They also show dramatic selectivity to mercury ions in presence of other interfering ions, Pb2+, Zn2+and Ca2+.

scholarly journals From a precursor to an etchant: spontaneous inversion of the role of Au(iii) chloride for one-pot synthesis of smooth and spherical gold nanoparticles

2019 ◽  
Vol 1 (6) ◽  
pp. 2157-2161 ◽  
Author(s):  
Seokyoung Yoon ◽  
Chansong Kim ◽  
Byoungsang Lee ◽  
Jung Heon Lee
Keyword(s):  
Gold Nanoparticles ◽  
Facile Synthesis ◽  
One Pot ◽  
One Pot Synthesis ◽  
Spherical Gold Nanoparticles

Inversion of the role of Au(iii) chloride allows facile synthesis of smooth and spherical AuNPs with nanoscale size tunability.

A Highly Sensitive Resonance Rayleigh Scattering Method for Platelet-Derived Growth Factor Using Aptamer-Nanogold Probe as Catalyst of the Cu2O Particle Reaction

2013 ◽  
Vol 680 ◽  
pp. 137-140
Author(s):  
Dong Mei Yao ◽  
Gui Qing Wen ◽  
Jian Niao Tian ◽  
Zhi Liang Jiang ◽  
Ai Hui Liang
Keyword(s):  
Gold Nanoparticles ◽  
Growth Factor ◽  
Rayleigh Scattering ◽  
Sodium Citrate ◽  
Reducing Agent ◽  
Platelet Derived Growth Factor ◽  
Resonance Rayleigh Scattering ◽  
Scattering Method ◽  
Highly Sensitive

Using sodium citrate as reducing agent, different sizes of gold nanoparticles(GN) were prepared, and were modified by platelet-derived growth factor (PDGF) aptamer to obtain stable aptamer-nanogold probes (Apt-GN). The probe specifically combined with PDGF-AA to form Apt-GN-PDGF-AA clusters that exhibited a resonance Rayleigh scattering (RRS) peak at 550 nm. The RRS intensity ΔI550nmwas linear to the PDGF-AA concentration in the range of 0.33-40 ng/ml. The probe has strong catalysis of the Fehling reagent-glucose Cu2O particle reaction that can be monitored by RRS technique at 610 nm, but the cluster is very weak. When PDGF-AA concentration increased, the Apt-GN decreased, and the RRS intensity at 610 nm decreased. The decreased RRS intensity ΔI610nmwas linear to PDGF-AA concentration in the range of 0.03-26.67 ng/mL. Accordingly, two new aptamer-nanogold RRS methods were established.

scholarly journals Shape-Controlled Generation of Gold Nanoparticles Assisted by Dual-Molecules: The Development of Hydrogen Peroxide and Oxidase-Based Biosensors

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Chifang Peng ◽  
Xiaohui Duan ◽  
Zhengjun Xie ◽  
Chunli Liu
Keyword(s):  
Gold Nanoparticles ◽  
Sodium Citrate ◽  
Chloroauric Acid ◽  
One Pot ◽  
Naked Eye ◽  
Different Shapes ◽  
Shape Controlled ◽  
Ethanesulfonic Acid ◽  
Mediated Reduction ◽  
Anisotropic Metal

With the assist of dual-molecules, 2-(N-morpholino)ethanesulfonic acid (MES) and sodium citrate, gold nanoparticles (GNPs) with different shapes can be generated in the H2O2-mediated reduction of chloroauric acid. This one-pot reaction can be employed to sensitively detect H2O2, probe substrates or enzymes in oxidase-based reactions as well as prepare branched GNPs controllably. By the “naked eye,” 20 μM H2O2, 0.1 μM glucose, and 0.26 U/mL catalase could be differentiated, respectively. By spectrophotometer, the detected limits of H2O2, glucose, and catalase were 1.0 μM, 0.01 μM, and 0.03 U/mL, respectively, and the detection linear ranges for them were 5.0–400 μM, 0.01–0.3 mM, and 0.03–0.78 U/mL, respectively. The proposed “dual-molecules assist” strategy probably paves a new way for the fabrication of nanosensors based on the growth of anisotropic metal nanoparticles, and the developed catalase sensor can probably be utilized to fabricate ultrasensitive ELISA methods for various analytes.

CONTROLLING THE SIZE AND SIZE DISTRIBUTION OF GOLD NANOPARTICLES: A DESIGN OF EXPERIMENT STUDY

2012 ◽  
Vol 11 (02) ◽  
pp. 1250023 ◽  
Author(s):  
DHIRAJ KUMAR ◽  
BRIAN J MEENAN ◽  
ISHA MUTREJA ◽  
RAECHELLE D'SA ◽  
DORIAN DIXON
Keyword(s):  
Gold Nanoparticles ◽  
Size Distribution ◽  
Design Of Experiment ◽  
Metallic Nanoparticles ◽  
Sodium Citrate ◽  
Chloroauric Acid ◽  
Production Volume ◽  
Synthesis Of Nanoparticles ◽  
Potential Applications ◽  
Poly Ethylene

The Turkevich method is the oldest and most widely employed protocol for the production of colloidal gold. Gold nanoparticles are nontoxic in nature and have potential applications in various biomedical fields including drug delivery and bioimaging. These metallic nanoparticles can be functionalized with drugs, targeting ligands such as tumor necrosis factor and groups (e.g., Poly ethylene glycol) to provide shielding from undesired immune responses. In this study we investigate the influence of process variables on the synthesis of nanoparticles by the reduction of chloroauric acid ( HAuCl4 ) solution with sodium citrate. A design of experiment (DoE) approach was used to investigate the influence of production volume, temperature, stirring rate and sodium citrate concentration on the physical properties of the nanoparticles namely size, size distribution, zeta potential and UV-Vis characteristics. The study showed that the relative amount of sodium citrate added ( Au /citrate mole ratio) had a significant effect on the size, poly dispersity index (PDI), the number of peaks in the size distribution and the position of Lambda max in the UV-Vis spectra. By varying the Au /Citrate ratio it is possible to synthesize particles with average diameters from 20 to 80 nm. However, the use of low amounts of sodium citrate in order to produce particles larger than ~35 nm tends to result in a wide bimodal size distribution.

scholarly journals SÍNTESE E CARACTERIZAÇÃO DE NANOPARTÍCULAS DE OURO COLOIDAL COM O LÁTEX COMO UM AGENTE REDUTOR

Nativa ◽  
2019 ◽  
Vol 7 (3) ◽  
pp. 268
Author(s):  
Pedro Henrique da Conceição Silva ◽  
Anselmo Fortunato Ruiz Rodriguez
Keyword(s):  
Gold Nanoparticles ◽  
Green Synthesis ◽  
Low Cost ◽  
Colloidal Suspension ◽  
Reducing Agent ◽  
Synthesis Of Nanoparticles ◽  
Chemical Reagents ◽  
The North ◽  
Toxic Agents ◽  
Croton Lechleri

Tradicionalmente as técnicas de síntese de nanopartículas utilizam solventes tóxicos, o que gera resíduos potencialmente nocivos tanto à saúde quanto ao meio ambiente. Buscando metodologias mais sustentáveis na síntese de nanopartículas várias pesquisas têm proposto a utilização de agentes biológicos ou parte deles, em substituição aos reagentes químicos tóxicos. Assim, este trabalho propôs sintetizar nanopartículas de ouro, utilizando síntese verde, ou seja, o látex da planta Sangue de Dragão (Croton lechleri Müll. Arg.) como agente redutor. A planta Sangue de Dragão é nativa dos países Peru e Bolívia, no Brasil ela é encontrada na região Norte, nos estados Rondônia, Acre e Amazonas. Para realizar a síntese de nanopartículas, em busca de condições de síntese e de aperfeiçoamento de parâmetros, utilizou-se a técnica de visão de nanopartículas em suspensão coloidal e estabilidade, com monodispersividade. Obtendo-se monodispersidade das nanopartículas de ouro, sendo formadas nanopartículas que se encontram no diâmetro entre 10 nm e 40 nm. O potencial zeta esteve na faixa de da região de +/- 30 mV, também foi observado que as partículas se agregam com uma dispersão instável, no decorrer do tempo. A síntese verde utilizando o látex da planta Sangue de Dragão apresentou-se resultados compatíveis com as técnicas que utilizam os agentes tóxicos, porem sustentável e com baixo custo para a realização.Palavras-chave: Croton lechleri, nanopartículas de ouro, ressonância plasmônica superficial. SYNTHESIS AND CHARACTERIZATION OF COLOIDAL GOLD NANOPARTICLES WITH LATEX AS A REDUCING AGENT ABSTRACT: Traditionally the techniques of synthesis of nanoparticles use toxic solvents, which generate residues potentially harmful to health and the environment. Looking for more sustainable methodologies in the synthesis of nanoparticles several researches has proposed the use of biological agents or part of them, replacing the toxic chemical reagents. Thus, this work proposed to synthesize gold nanoparticles, using green synthesis, that is, the latex of the Dragon Blood plant (Croton lechleri Müll. Arg.) As a reducing agent. The Dragon Blood plant is native to Peru and Bolivia, in Brazil it is found in the North region, in the states of Rondônia, Acre and Amazonas. To perform the synthesis of nanoparticles, searching for conditions of synthesis and improvement of parameters, the technique of nanoparticle vision in colloidal suspension and stability, with monodispersivity, was used. Obtaining monodispersity of the gold nanoparticles, being formed nanoparticles that are in the diameter between 10 nm and 40 nm. The zeta potential was within the range of +/- 30 mV, it was also observed that the particles aggregate with an unstable dispersion over time. The green synthesis using the latex of the Dragon Blood plant presented results compatible with the techniques that use the toxic agents, but sustainable and with low cost to the realization.Keywords: Croton lechleri, gold nanoparticles, superficial plasmon resonance.

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