scholarly journals A Rare Natural Benzo[k,l]xanthene as a Turn-Off Fluorescent Sensor for Cu2+ Ion

2020 ◽  
Vol 21 (18) ◽  
pp. 6933
Author(s):  
Giuseppe Floresta ◽  
Nunzio Cardullo ◽  
Carmela Spatafora ◽  
Antonio Rescifina ◽  
Corrado Tringali
Keyword(s):  
Fluorescent Probe ◽  
Fluorescence Intensity ◽  
Limit Of Detection ◽  
Copper Ions ◽  
Fluorescent Sensor ◽  
Copper Ion ◽  
Living Cells ◽  
A Value ◽  
Wide Range ◽  
Catechol Group

Rapid and efficient analyses of copper ions are crucial to providing key information for Cu2+ in living cells because of their biological importance. In this study, we reported one new turn-off fluorescent sensor for Cu2+ with a benzo[k,l]xanthene core, which served as an efficient cation sensor for copper ion over a wide range of other cations (Na+, K+, Ag+, Hg2+, Cd2+, Co2+, Ni2+, Zn2+, Mg2+, and Fe3+) owing to the catechol group in the aromatic core. The sensor showed selectivity for Cu2+ over other ions; the logKβ for Cu2+ binding to compound 1 had a value of 13.265. In the presence of Cu2+, sensor 1 provided significant fluorescence decrement; Co2+, and Ni2+ caused a fluorescence decrement when employed at a higher concentration than Cu2+, while Na+, K+, Hg2+, Cd2+, Zn2+, and Mg2+ metal ions produced only minor changes in fluorescence intensity. Fluorescence experiments demonstrate that compound 1 may have an application as a fluorescent probe for detecting Cu2+ with a limit of detection of 0.574 µM.

High selectivity and reversibility/reusability red emitting fluorescent probe for copper ions detection and imaging in living cells

2019 ◽  
Vol 206 ◽  
pp. 125-131 ◽  
Author(s):  
Hanzhi Ni ◽  
Qingming Wang ◽  
Lei Jin ◽  
Wenling Wang ◽  
Lihui Dai ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
Copper Ions ◽  
Living Cells

A highly selective turn-on fluorescent sensor for fluoride and its application in imaging of living cells

2014 ◽  
Vol 38 (12) ◽  
pp. 6198-6204 ◽  
Author(s):  
Jiun-Ting Yeh ◽  
Parthiban Venkatesan ◽  
Shu-Pao Wu
Keyword(s):  
Fluorescent Probe ◽  
Fluorescence Enhancement ◽  
Fluorescent Sensor ◽  
Living Cells ◽  
Green Fluorescence ◽  
Turn On ◽  
Highly Sensitive

A highly sensitive and selective fluorescent probe (FS) is based on a fluoride-specific desilylation reaction to yield a significant green fluorescence enhancement.

scholarly journals A “weak acid and weak base” type fluorescent probe for sensing pH: mechanism and application in living cells

RSC Advances ◽  
2019 ◽  
Vol 9 (36) ◽  
pp. 20982-20988 ◽  
Author(s):  
Chunpeng Jiao ◽  
Jingxiang Pang ◽  
Li Shen ◽  
Wenjuan Lu ◽  
Pingping Zhang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescence Intensity ◽  
Living Cells ◽  
Weak Acid ◽  
Weak Base

When the probe was in the protonation process, the fluorescence intensity gradually decreased, whereas when the probe was in the deprotonation process, the fluorescence intensity gradually increased.

A new “on–off” fluorescent probe for the selective detection of copper ions in living cells

2017 ◽  
Vol 9 (26) ◽  
pp. 3956-3961 ◽  
Author(s):  
Mingjie Wei ◽  
Youyu Zhang ◽  
Haitao Li ◽  
Shouzhuo Yao
Keyword(s):  
Fluorescent Probe ◽  
Copper Ions ◽  
Living Cells ◽  
Selective Detection

A new “on–off” fluorescent probe 4′,5′-bis((bis(thiophen-2-ylmethyl)amino)methyl)-2′,7′-dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (probe F) for the selective detection of copper ions was synthesized and characterized.

Single fluorescent probe for reversibly detecting copper ions and cysteine in a pure water system

RSC Advances ◽  
2016 ◽  
Vol 6 (37) ◽  
pp. 30951-30955 ◽  
Author(s):  
Yong Liu ◽  
Fangfang Meng ◽  
Weiying Lin
Keyword(s):  
Fluorescent Probe ◽  
Copper Ions ◽  
Pure Water ◽  
Copper Ion ◽  
Water System ◽  
System P ◽  
First Time

In this work, we have engineered a novel fluorescent probe PI, which remarkably can reversible detect copper ion and cysteine in pure water system for the first time.

A new turn-on fluorescent probe towards hypochlorite in living cells

2017 ◽  
Vol 9 (5) ◽  
pp. 864-870 ◽  
Author(s):  
Jing Guo ◽  
Zhixiang Zhang ◽  
Ziyu Kuai ◽  
Rui Wang ◽  
Qingbiao Yang ◽  
...  
Keyword(s):  
Excited State ◽  
Fluorescent Probe ◽  
Fluorescent Sensor ◽  
Living Cells ◽  
Turn On ◽  
First Excited State

A novel turn-on fluorescent sensor PIPH based on changes in the internal conformation between the ground and first excited state.

scholarly journals A Novel Fluorescent Probe for Hydrogen Peroxide and Its Application in Bio-Imaging

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3352
Author(s):  
Yingying Zuo ◽  
Yang Jiao ◽  
Chunming Ma ◽  
Chunying Duan
Keyword(s):  
Hydrogen Peroxide ◽  
Fluorescent Probe ◽  
Human Body ◽  
Fluorescence Enhancement ◽  
Fluorescent Sensor ◽  
Living Cells ◽  
Promising Tool ◽  
Bio Imaging ◽  
Good Biocompatibility ◽  
The Relationship

Hydrogen peroxide (H2O2) plays an important role in the human body and monitoring its level is meaningful due to the relationship between its level and diseases. A fluorescent sensor (CMB) based on coumarin was designed and its ability for detecting hydrogen peroxide by fluorescence signals was also studied. The CMB showed an approximate 25-fold fluorescence enhancement after adding H2O2 due to the interaction between the CMB and H2O2 and had the potential for detecting physiological H2O2. It also showed good biocompatibility and permeability, allowing it to penetrate cell membranes and zebrafish tissues, thus it can perform fluorescence imaging of H2O2 in living cells and zebrafish. This probe is a promising tool for monitoring the level of H2O2 in related physiological and pathological research.

scholarly journals Ion-Imprinted Polymer Modified with Carbon Quantum Dots as a Highly Sensitive Copper(II) Ion Probe

Polymers ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 1376
Author(s):  
Zhiming Wang ◽  
Cuo Zhou ◽  
Shunwei Wu ◽  
Chunyan Sun
Keyword(s):  
Quantum Dots ◽  
Copper Ions ◽  
Fluorescent Sensor ◽  
Hydrothermal Process ◽  
Copper Ion ◽  
Fluorescence Analysis ◽  
Carbon Quantum Dots ◽  
General Strategy ◽  
Surface Imprinting Technique ◽  
Ion Imprinted

Fluorescence analysis technology and ion imprinting technology are combined to prepare a copper ion fluorescence sensor. Carbon quantum dots (CQDs), with a quantum yield of 79%, were synthesized by a hydrothermal process using citric acid as the carbon source. The prepared CQDs, acting as the fluorophore, were grafted onto the surface of an SBA-15 mesoporous molecular sieve by an amidation reaction. Then, the fluorescent sensor CQDs@Cu-IIP was prepared using a surface imprinting technique with the modified SBA-15 as the substrate, copper ions as a template, tetraethoxysilane as the crosslinker, and 3-aminopropyl-3-ethoxysilane as the functional monomers. The sensor showed strong fluorescence from CQDs and high selectivity due to the presence of Cu(II)-IIP. After the detection conditions were optimized, the fluorescence intensity of the sensor had good linearity with Cu(II) concentration in a linear range of 0.25–2 mg/L and 3–10 mg/L. This CQDs@Cu-IIP was applied to the determination of traces Cu(II) in real water samples and good recoveries of 99.29–105.42% were obtained. The present study provides a general strategy for fabricating materials based on CQDs for selective fluorescence detection of heavy metals.

scholarly journals Design and Synthesis of New Acridone-Based Nitric Oxide Fluorescent Probe

Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4340
Author(s):  
Mikhail Panfilov ◽  
Darya Chernova ◽  
Irina Khalfina ◽  
Alexander Moskalensky ◽  
Aleksey Vorob’ev
Keyword(s):  
Nitric Oxide ◽  
Fluorescent Probe ◽  
Fluorescence Intensity ◽  
Aqueous Media ◽  
Fluorescent Imaging ◽  
Jurkat Cells ◽  
Triazole Derivative ◽  
Design And Synthesis ◽  
Wide Range ◽  
Biochemical Studies

Nitric oxide (NO) is an important signaling molecule involved in a wide range of physiological and pathological processes. Fluorescent imaging is a useful tool for monitoring NO concentration, which could be essential in various biological and biochemical studies. Here, we report the design of a novel small-molecule fluorescent probe based on 9(10H)acridone moiety for nitric oxide sensing. 7,8-Diamino-4-carboxy-10-methyl-9(10H)acridone reacts with NO in aqueous media in the presence of O2, yielding a corresponding triazole derivative with fivefold increased fluorescence intensity. The probe was shown to be capable of nitric oxide sensing in living Jurkat cells.

Near-infrared fluorogenic switches for the detection of Hg(ii) ions: applications in real samples and living cells

2019 ◽  
Vol 11 (21) ◽  
pp. 2769-2777 ◽  
Author(s):  
Asaithambi Gomathi ◽  
Periasamy Viswanathamurthi
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Cell Imaging ◽  
Limit Of Detection ◽  
Stokes Shift ◽  
Living Cells ◽  
Imaging Studies ◽  
Real Samples ◽  
Large Stokes Shift

A novel near-infrared fluorescent probe NIRM was designed and synthesized. The probe exhibited a low limit of detection for Hg2+ (3.2 nM) as well as a large Stokes shift (115 nm), which is very favorable for cell imaging studies.

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