scholarly journals Efficacy of Biophysical Energies on Healing of Diabetic Skin Wounds in Cell Studies and Animal Experimental Models: A Systematic Review

2019 ◽  
Vol 20 (2) ◽  
pp. 368 ◽  
Author(s):  
Rachel Kwan ◽  
Song Lu ◽  
Harry Choi ◽  
Luther Kloth ◽  
Gladys Cheing

We have systematically assessed published cell studies and animal experimental reports on the efficacy of selected biophysical energies (BPEs) in the treatment of diabetic foot ulcers. These BPEs include electrical stimulation (ES), pulsed electromagnetic field (PEMF), extracorporeal shockwave (ECSW), photo energies and ultrasound (US). Databases searched included CINAHL, MEDLINE and PubMed from 1966 to 2018. Studies reviewed include animal and cell studies on treatment with BPEs compared with sham, control or other BPEs. Information regarding the objective measures of tissue healing and data was extracted. Eighty-two studies were eventually selected for the critical appraisal: five on PEMF, four each on ES and ECSW, sixty-six for photo energies, and three about US. Based on the percentage of original wound size affected by the BPEs, both PEMF and low-level laser therapy (LLL) demonstrated a significant clinical benefit compared to the control or sham treatment, whereas the effect of US did not reveal a significance. Our results indicate potential benefits of selected BPEs in diabetic wound management. However, due to the heterogeneity of the current clinical trials, comprehensive studies using well-designed trials are warranted to confirm the results.

2012 ◽  
Vol 28 (3) ◽  
pp. 901-909 ◽  
Author(s):  
Yusuf Emes ◽  
Kivanç Akça ◽  
Buket Aybar ◽  
Serhat Yalçın ◽  
Yeliz Çavuşoğlu ◽  
...  

2015 ◽  
Vol 33 (3) ◽  
pp. 123-128 ◽  
Author(s):  
Fabrício Poletto Massotti ◽  
Fernando Vacilotto Gomes ◽  
Luciano Mayer ◽  
Marília Gerhardt de Oliveira ◽  
Carlos Eduardo Baraldi ◽  
...  

2017 ◽  
Vol 8 (2) ◽  
pp. 151-153
Author(s):  
Sudhanva H.K. ◽  
◽  
Chittoria R.K. ◽  
Pandey S. ◽  
Mohapatra D.P. ◽  
...  

2014 ◽  
Vol 7 (1) ◽  
pp. 14 ◽  
Author(s):  
HamedGhoddusi Johari ◽  
Babak Sabet ◽  
Sam Zeraatian ◽  
Bita Geramizedeh ◽  
Hossein Hodjati ◽  
...  

2021 ◽  
Vol 10 (4) ◽  
pp. 772
Author(s):  
Hahn Jin Jung ◽  
Young-Jun Chung ◽  
Young-Seok Choi ◽  
Phil Sang Chung ◽  
Ji-Hun Mo

Allergic rhinitis (AR) is a common disease that interferes with the daily activities and reduces the quality of life. Conventional treatments often do not provide complete resolution of the symptoms, and many new treatment modalities have been tried. This study aimed to evaluate the efficacy and safety of low-level laser therapy (LLLT) for AR in a randomized, double-blind, placebo-controlled trial. Patients diagnosed with AR were randomly allocated to receive LLLT or sham treatment. The primary outcome was a change in the reflective total nasal symptom score (TNSS). The secondary outcome was quality of life scores assessed using the Rhinoconjunctivitis Quality of Life Questionnaire. Incidences of adverse events were also recorded. Among 67 randomized subjects, 41 subjects (22 in LLLT group and 19 in sham treatment group) were included for efficacy analysis. The LLLT group showed a significantly improved TNSS score compared to the sham treatment group for decreasing AR symptom severity (p = 0.011) and improving quality of life regarding nasal symptoms (p = 0.036) at the end of treatment. Throughout the treatment period, no severe adverse events occurred. This clinical trial showed that LLLT is an effective and safe option for the management of AR regarding symptom relief and quality of life improvement.


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