scholarly journals Knockout of Murine Mamld1 Impairs Testicular Growth and Daily Sperm Production but Permits Normal Postnatal Androgen Production and Fertility

2017 ◽  
Vol 18 (6) ◽  
pp. 1300 ◽  
Author(s):  
Mami Miyado ◽  
Kaoru Yoshida ◽  
Kenji Miyado ◽  
Momori Katsumi ◽  
Kazuki Saito ◽  
...  
Keyword(s):  
Sperm Production ◽  
Testicular Growth ◽  
Daily Sperm Production

scholarly journals Number and function of Sertoli cells, number and yield of spermatogonia, and daily sperm production in three breeds of boar

Reproduction ◽  
1996 ◽  
Vol 107 (1) ◽  
pp. 137-149 ◽  
Author(s):  
O. E. Okwun ◽  
G. Igboeli ◽  
J. J. Ford ◽  
D. D. Lunstra ◽  
L. Johnson
Keyword(s):  
Sertoli Cells ◽  
Sperm Production ◽  
And Function ◽  
Daily Sperm Production

scholarly journals Determination of Daily Sperm Production (DSP) in Rabbit (Oryctolagus cuniculus) Bucks using Testicular Parameters

2015 ◽  
Vol 5 (4) ◽  
pp. 141-148
Author(s):  
Olumuyiwa Joseph Olarotimi ◽  
◽  
Olujide Adedamola Sokunbi ◽  
Abdur-Rahman Abdullah ◽  
◽  
...  
Keyword(s):  
Oryctolagus Cuniculus ◽  
Sperm Production ◽  
Daily Sperm Production

Effect of mouse epidermal growth factor on fertility in rams

1990 ◽  
Vol 41 (6) ◽  
pp. 1147 ◽  
Author(s):  
BW Brown ◽  
PE Mattner ◽  
BA Panaretto ◽  
GH Brown ◽  
BD Gream ◽  
...  
Keyword(s):  
Body Weight ◽  
Survival Rate ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Post Treatment ◽  
Sperm Production ◽  
Teratogenic Effects ◽  
Progressive Motility ◽  
Epidermal Growth ◽  
Daily Sperm Production

Seminal characteristics and flock fertility were studied in Merino rams treated with mouse epidermal growth factor (EGF). Intravenous infusions of 105 8g EGF/kg body weight over 24 h in five rams had no statistically significant effect on daily sperm production measured from 6-10 weeks after dosing or on the percentages of spermatozoa that were unstained (nigrosinleosin stain) or morphologically normal. At 7-8 weeks post treatment, the percentage of spermatozoa exhibiting progressive motility was significantly reduced (P<0.05). By 9-10 weeks after treatment, the seminal characteristics were normal in all rams. In 1987, eight rams and in 1988, six ofthe same rams, were joined with ewes for 6 weeks (at a rate of 2%) 12 weeks after s.c. injection of 150 8g/kg body weight. Compared with the performance of control rams, EGF had no significant effect on ram fertility, nor did it produce any teratogenic effects in their progeny or effect their survival rate.

Prolonged deleterious effects of neonatal handling on reproductive parameters of pubertal male rats

2006 ◽  
Vol 18 (4) ◽  
pp. 497 ◽  
Author(s):  
Renata Mazaro ◽  
Teresa Lúcia Lamano-Carvalho
Keyword(s):  
Sertoli Cells ◽  
Seminiferous Tubule ◽  
Male Rats ◽  
Germinal Epithelium ◽  
Reproductive Parameters ◽  
Sperm Production ◽  
Neonatal Handling ◽  
Epithelium Thickness ◽  
Cauda Epididymidis ◽  
Daily Sperm Production

The purpose of the present study was to investigate the long-lasting effects of neonatal handling on reproductive parameters of male rats. Neonatal handling (pups separated from their mothers, kept isolated at environmental temperature for 20 min and submitted to 1 min of tactile stimulation) was applied from post partum Days 1 to 14 (a stress-hyporesponsive period, SHRP) and the animals were killed at puberty (61 days of age). The number of mature spermatids and the daily sperm production were estimated in homogenates from the right testes and cauda epididymidis. Histometric parameters (diameter of seminiferous tubule, germinal epithelium thickness and number of Sertoli cells) were evaluated in paraplast sections of the left testes. The association of the slightly aversive stimuli applied during the SHRP proved to have lasting deleterious effects on male reproduction, causing lower testicular weight and reduced values of seminiferous tubule diameter and germinal epithelium thickness at puberty, which resulted in a 25% reduction in the daily sperm production and in the number of mature spermatids. Similarly, the number of Sertoli cells per tubular cross section was 20% smaller and the weight and number of spermatozoa were reduced more than 40% in the cauda epididymidis of animals handled.

INHIBIN BIOACTIVITY IN HUMAN TESTICULAR EXTRACTS

1987 ◽  
Vol 115 (2) ◽  
pp. R9-R12 ◽  
Author(s):  
B.J.B. Simpson ◽  
C.G. Tsonis ◽  
F.C.W. Wu
Keyword(s):  
Plasma Concentrations ◽  
Pituitary Cell ◽  
Untreated Group ◽  
Testicular Function ◽  
Sperm Production ◽  
The Mean ◽  
The Relationship ◽  
Daily Sperm Production

ABSTRACT Inhibin bioactivity was measured in human testicular extracts by a sensitive sheep pituitary cell bioassay. The relationship between testicular inhibin bioactivity, daily sperm production (DSP) and plasma concentrations of FSH, LH, testosterone and oestradiol were examined. The mean level of testicular inhibin bioactivity was 4.4 ±1.3 U/g (mean ± SD) with a significantly lower value in those who received radiotherapy (3.2 ± 1.4 U/g) than in the untreated group (4.8 ± 1.1 U/g). In contrast to the rat, human testicular inhibin bioactivity was not significantly correlated to FSH or DSP. These findings suggest that inhibin may have a complex role in normal and/or pathological testicular function.

Studies of zinc nutrition in sheep. I. The relation of zinc to growth, testicular development, and spermatogenesis in young rams

1969 ◽  
Vol 20 (5) ◽  
pp. 889 ◽  
Author(s):  
EJ Underwood ◽  
M Somers
Keyword(s):  
Zinc Deficiency ◽  
Size Structure ◽  
Clinical Signs ◽  
Feed Consumption ◽  
Testicular Development ◽  
Sperm Production ◽  
Poor Growth ◽  
Testicular Growth ◽  
Ram Lambs ◽  
And Function

Ram lambs fed on a diet containing 2.4 p.p.m. zinc made poor growth, developed clinical signs of severe zinc deficiency, showed impaired testicular growth, and showed a complete cessation of spermatogenesis within a period of 20–24 weeks. Lambs fed on the same diet supplemented with zinc sulphate to provide total zinc levels of 17.4 and 32.4 p.p.m. had a higher feed intake, made significantly greater liveweight gains, and showed no signs of zinc deficiency. Testicular growth and sperm production were markedly improved by both the zinc supplements. No differences in liveweight gains or feed consumption between the two supplemented groups were observed but testicular growth and sperm production were highly significantly greater in the lambs receiving the larger zinc supplement. It was concluded that a dietary zinc intake of 17.4 p.p.m. is adequate for growth of ram lambs but is inadequate for normal testicular development and function. Lambs in which consumption of the diet containing 32.4 p.p.m. zinc was restricted to that of the zinc-deficient group showed no significant improvement in liveweight gains, but testicular development and sperm production were significantly greater than in the zinc-deficient lambs. Complete remission of all signs of zinc deficiency and full recovery of testicular size, structure, and function were achieved in a zinc repletion period lasting 20 weeks.

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