scholarly journals Role of RHEB in Regulating Differentiation Fate of Mesenchymal Stem Cells for Cartilage and Bone Regeneration

2017 ◽  
Vol 18 (4) ◽  
pp. 880 ◽  
Author(s):  
Sajjad Ashraf ◽  
In-Bo Han ◽  
Hansoo Park ◽  
Soo-Hong Lee
Oncotarget ◽  
2017 ◽  
Vol 8 (13) ◽  
pp. 21031-21043 ◽  
Author(s):  
Deting Xue ◽  
Erman Chen ◽  
Wei Zhang ◽  
Xiang Gao ◽  
Shengdong Wang ◽  
...  

2017 ◽  
Vol 3 (1) ◽  
pp. 4 ◽  
Author(s):  
Reggie Hamdy ◽  
Yasir Alabdulkarim ◽  
Bayan Ghalimah ◽  
Mohammad Al-Otaibi ◽  
HadilF Al-Jallad ◽  
...  

2007 ◽  
Vol 342-343 ◽  
pp. 193-196
Author(s):  
Ho Yun Chung ◽  
Eun Jung Oh ◽  
Jin Hyun Choi ◽  
Byung Chae Cho

Mesenchymal stem cells (MSCs) from bone marrow seem to be the one of best candidates to regenerate injured tissue. However, recent advances in application of MSCs toward large tissue regeneration are faced with lack of vascularity. In this study, endothelial cells differentiated from MSCs were applied for constructing tissue-engineered bone and cartilage. It was found that endothelial cells from MSCs play an important role of providing vasculature.


2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Yuetian Li ◽  
Xinyue Wang ◽  
Yu Pang ◽  
Shuangcheng Wang ◽  
Meng Luo ◽  
...  

As one of the most serious complications of radiotherapy, osteoradionecrosis (ORN) seriously affects the quality of life of patients and even leads to death. Vascular injury and immune disorders are the main causes of bone lesions. The traditional conservative treatment of ORN has a low cure rate and high recurrent. Exosomes are a type of extracellular bilayer lipid vesicles secreted by almost all cell types. It contains cytokines, proteins, mRNA, miRNA, and other bioactive cargos, which contribute to several distinct processes. The favorable biological functions of mesenchymal stem cells-derived exosomes (MSC exosomes) include angiogenesis, immunomodulation, bone regeneration, and ferroptosis regulation. Exploring the characteristic of ORN and MSC exosomes can promote bone regeneration therapies. In this review, we summarized the current knowledge of ORN and MSC exosomes and highlighted the potential application of MSC exosomes in ORN treatment.


Author(s):  
Ruggero Rodriguez y Baena ◽  
Silvana Rizzo ◽  
Antonio Graziano ◽  
Saturnino Marco Lupi

2013 ◽  
Vol 37 (12) ◽  
pp. 2491-2498 ◽  
Author(s):  
Xin Wang ◽  
Yu Wang ◽  
Wenlong Gou ◽  
Qiang Lu ◽  
Jiang Peng ◽  
...  

Biomaterials ◽  
2014 ◽  
Vol 35 (25) ◽  
pp. 6859-6870 ◽  
Author(s):  
Xueqin Gao ◽  
Arvydas Usas ◽  
Ying Tang ◽  
Aiping Lu ◽  
Jian Tan ◽  
...  

Biomaterials ◽  
2016 ◽  
Vol 75 ◽  
pp. 279-294 ◽  
Author(s):  
Qing Xie ◽  
Zi Wang ◽  
Huifang Zhou ◽  
Zhang Yu ◽  
Yazhuo Huang ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document