scholarly journals The role of hesperetin on osteogenesis of human mesenchymal stem cells and its function in bone regeneration

Oncotarget ◽  
2017 ◽  
Vol 8 (13) ◽  
pp. 21031-21043 ◽  
Author(s):  
Deting Xue ◽  
Erman Chen ◽  
Wei Zhang ◽  
Xiang Gao ◽  
Shengdong Wang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Bone Regeneration ◽  
Human Mesenchymal Stem Cells

scholarly journals A comparison of bone regeneration with human mesenchymal stem cells and muscle-derived stem cells and the critical role of BMP

Biomaterials ◽  
2014 ◽  
Vol 35 (25) ◽  
pp. 6859-6870 ◽  
Author(s):  
Xueqin Gao ◽  
Arvydas Usas ◽  
Ying Tang ◽  
Aiping Lu ◽  
Jian Tan ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Bone Regeneration ◽  
Critical Role ◽  
Human Mesenchymal Stem Cells

Magnetic field assisted stem cell differentiation – role of substrate magnetization in osteogenesis

2015 ◽  
Vol 3 (16) ◽  
pp. 3150-3168 ◽  
Author(s):  
Sunil Kumar Boda ◽  
Greeshma Thrivikraman ◽  
Bikramjit Basu
Keyword(s):  
Magnetic Field ◽  
Tissue Engineering ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Bone Tissue Engineering ◽  
Human Mesenchymal Stem Cells ◽  
Stem Cell Differentiation

Substrate magnetization as a tool for modulating the osteogenesis of human mesenchymal stem cells for bone tissue engineering applications.

Su1793 The Protective Role of Human Mesenchymal Stem Cells in Acute Pancreatitis in Mice

2013 ◽  
Vol 144 (5) ◽  
pp. S-478
Author(s):  
Michael Gonzales ◽  
Xuxia Gao ◽  
Yanna Cao ◽  
Hasen Xue ◽  
Judith Aronson ◽  
...  
Keyword(s):  
Stem Cells ◽  
Acute Pancreatitis ◽  
Mesenchymal Stem Cells ◽  
Human Mesenchymal Stem Cells ◽  
Protective Role

scholarly journals Role of Wnt-5a in the Determination of Human Mesenchymal Stem Cells into Preadipocytes

2009 ◽  
Vol 285 (9) ◽  
pp. 6170-6178 ◽  
Author(s):  
Roman Bilkovski ◽  
Dominik M. Schulte ◽  
Frank Oberhauser ◽  
Matthias Gomolka ◽  
Michael Udelhoven ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Human Mesenchymal Stem Cells

Synergistic Material-Topography Combinations to Achieve Immunomodulatory Osteogenic Biomaterials

2020 ◽  
Author(s):  
Laurence Burroughs ◽  
Mahetab H. Amer ◽  
Matthew Vassey ◽  
Britta Koch ◽  
Grazziela P Figueredo ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Bone Regeneration ◽  
Human Mesenchymal Stem Cells ◽  
Cell Phenotype ◽  
Macrophage Phenotype ◽  
Immunomodulatory Effects ◽  
Material Chemistry ◽  
Basal Media ◽  
Screening Platform

AbstractHuman mesenchymal stem cells (hMSCs) are widely represented in ongoing regenerative medicine clinical trials due to their ease of autologous implantation. In bone regeneration, crosstalk between macrophages and hMSCs is critical with macrophages playing a key role in the recruitment and differentiation of hMSCs. However, engineered biomaterials able to both direct hMSC fate and modulate macrophage phenotype have not yet been identified. A novel combinatorial chemistry-microtopography screening platform, the ChemoTopoChip, is used to identify materials suitable for bone regeneration by screening with human immortalized mesenchymal stem cells (hiMSCs) and human macrophages. The osteoinduction achieved in hiMSCs cultured on the “hit” materials in basal media is comparable to that seen when cells are cultured in osteogenic media, illustrating that these materials offer a materials-induced alternative in bone-regenerative applications. These also exhibit immunomodulatory effects, concurrently polarizing macrophages towards a pro-healing phenotype. Control of cell response is achieved when both chemistry and topography are recruited to instruct the required cell phenotype, combining synergistically. The large library of materials reveals that the relative roles of microtopography and material chemistry are similar, and machine learning identifies key material and topographical features for cell-instruction.

The association of human mesenchymal stem cells with BMP-7 improves bone regeneration of critical-size segmental bone defects in athymic rats

Bone ◽  
2010 ◽  
Vol 47 (1) ◽  
pp. 117-126 ◽  
Author(s):  
Giorgio Burastero ◽  
Sonia Scarfì ◽  
Chiara Ferraris ◽  
Chiara Fresia ◽  
Nadia Sessarego ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Bone Regeneration ◽  
Critical Size ◽  
Human Mesenchymal Stem Cells ◽  
Bone Defects ◽  
Segmental Bone ◽  
Segmental Bone Defects

Critical role of phosphoinositide 3-kinase cascade in adipogenesis of human mesenchymal stem cells

2007 ◽  
Vol 310 (1-2) ◽  
pp. 11-18 ◽  
Author(s):  
Weihua Yu ◽  
Zhenguang Chen ◽  
Jinli Zhang ◽  
Lirong Zhang ◽  
Hui Ke ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Critical Role ◽  
Human Mesenchymal Stem Cells ◽  
Kinase Cascade ◽  
Phosphoinositide 3 Kinase
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