scholarly journals Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/β-Catenin Pathway

2017 ◽  
Vol 18 (1) ◽  
pp. 133 ◽  
Author(s):  
Sara Cheleschi ◽  
Anna De Palma ◽  
Alessandra Pecorelli ◽  
Nicola Pascarelli ◽  
Giuseppe Valacchi ◽  
...  
2018 ◽  
Vol 66 ◽  
pp. 165-169 ◽  
Author(s):  
Anna De Palma ◽  
Sara Cheleschi ◽  
Nicola Antonio Pascarelli ◽  
Stefano Giannotti ◽  
Mauro Galeazzi ◽  
...  

2013 ◽  
Vol 18 (4) ◽  
pp. 273-287 ◽  
Author(s):  
Loris De Cecco ◽  
Matteo Dugo ◽  
Silvana Canevari ◽  
Maria Grazia Daidone ◽  
Maurizio Callari

Oncotarget ◽  
2017 ◽  
Vol 8 (42) ◽  
pp. 73345-73361 ◽  
Author(s):  
Patrick Wald ◽  
X. Shawn Liu ◽  
Cory Pettit ◽  
Mary Dillhoff ◽  
Andrei Manilchuk ◽  
...  

2013 ◽  
Vol 112 (3) ◽  
pp. 347-354 ◽  
Author(s):  
Aysegül Ilhan-Mutlu ◽  
Adelheid Wöhrer ◽  
Anna Sophie Berghoff ◽  
Georg Widhalm ◽  
Christine Marosi ◽  
...  

2017 ◽  
Vol 61 (12) ◽  
pp. 2153-2158 ◽  
Author(s):  
C. Giannitti ◽  
A. De Palma ◽  
N. A. Pascarelli ◽  
S. Cheleschi ◽  
N. Giordano ◽  
...  

2010 ◽  
Vol 21 (1) ◽  
pp. 68-73 ◽  
Author(s):  
C. Borel ◽  
S. Deutsch ◽  
A. Letourneau ◽  
E. Migliavacca ◽  
S. B. Montgomery ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261076
Author(s):  
Jeanne Cosandey ◽  
Eman Hamza ◽  
Vinzenz Gerber ◽  
Alessandra Ramseyer ◽  
Tosso Leeb ◽  
...  

MicroRNAs have been proposed as biomarkers for equine sarcoids, the most prevalent equine skin tumors globally. This study served to validate the diagnostic and prognostic potential of whole blood microRNAs identified in a previous study for long-term equine sarcoid diagnosis and outcome prediction. Based on findings of a clinical examination at the age of 3 years and a follow-up following a further 5–12 years, 32 Franches-Montagnes and 45 Swiss Warmblood horses were assigned to four groups: horses with regression (n = 19), progression (n = 9), new occurrences of sarcoid lesions (n = 19) and tumor-free control horses (n = 30). The expression levels for eight microRNAs (eca-miR-127, eca-miR-432, eca-miR-24, eca-miR-125a-5p, eca-miR-134, eca-miR-379, eca-miR-381, eca-miR-382) were analyzed through reverse transcription quantitative polymerase chain reaction in whole blood samples collected on initial examination. Associations of sex, breed, diagnosis, and prognosis with microRNA expression levels were examined using multivariable analysis of variance. Sex and breed influenced the expression level of five and two microRNAs, respectively. Eca-miR-127 allowed discrimination between sarcoid-affected and tumor-free horses. No variation in microRNA expression was found when comparing horses with sarcoid regression and progression. Expression levels of eca-miR-125a-5p and eca-miR-432 varied in male horses that developed sarcoids throughout the study period in comparison to male control horses. While none of the investigated miRNAs was validated for predicting the prognosis of sarcoid regression / progression within young horses with this condition, two miRNAs demonstrated potential to predict if young male (though not female) tumor-free horse can develop sarcoids within the following years. Sex- and breed- biased miRNAs exist within the equine species and have an impact on biomarker discovery.


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Daina Pamedytyte ◽  
Vaida Simanaviciene ◽  
Dalia Dauksiene ◽  
Enrika Leipute ◽  
Aurelija Zvirbliene ◽  
...  

2018 ◽  
Vol 50 (2) ◽  
pp. 276-284 ◽  
Author(s):  
Sahar Sarmasti Emami ◽  
Abolfazl Akbari ◽  
Ali-Akbar Zare ◽  
Shahram Agah ◽  
Mohsen Masoodi ◽  
...  

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