scholarly journals Leptin Receptor Gene Polymorphism and the Risk of Cardiovascular Disease: A Systemic Review and Meta-Analysis

2017 ◽  
Vol 14 (4) ◽  
pp. 375 ◽  
Author(s):  
Lei Wu ◽  
Dali Sun
Keyword(s):  
Cardiovascular Disease ◽  
Gene Polymorphism ◽  
Leptin Receptor ◽  
Meta Analysis ◽  
Receptor Gene ◽  
Systemic Review ◽  
Receptor Gene Polymorphism

scholarly journals Association of insulin resistance and leptin receptor gene polymorphism in type 2 diabetes mellitus

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Usha Adiga ◽  
Nandit Banawalikar ◽  
Sriprajna Mayur ◽  
Radhika Bansal ◽  
Nafeesath Ameera ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Gene Polymorphism ◽  
Leptin Receptor ◽  
Receptor Gene ◽  
Receptor Gene Polymorphism

Vitamin D (FokI) Receptor Gene Polymorphism is associated with Vitamin D Deficiency and Chronic Musculoskeletal Pain. A meta-analysis

2017 ◽  
Vol 87 (3-4) ◽  
pp. 219-232
Author(s):  
Ahmed Abdulahi Abdurahman ◽  
Leila Khorrami-nezhad ◽  
Khadijeh Mirzaei
Keyword(s):  
Vitamin D ◽  
Gene Polymorphism ◽  
Musculoskeletal Pain ◽  
Significant Interaction ◽  
Meta Analysis ◽  
Receptor Gene ◽  
Chronic Musculoskeletal Pain ◽  
Significant Interaction Effect ◽  
Heat Map ◽  
Receptor Gene Polymorphism

Abstract. Background: Musculoskeletal pain is the most common chronic pain experienced by older adults. The aim of this study is to explore the associations between vitamin D (FOKI) receptor gene polymorphism (VDR) and vitamin D deficiency (VDD) and chronic musculoskeletal pain. Methods: Cross-sectional studies published in English from January 2000 to January 2015which reported prevalence of chronic pain (CP) and chronic musculoskeletal pain (CMP) were included in this systematic review and meta-analysis. A heat map was used to visualize and observe the correlation between VDR and CMP, CP and VDD. Results: 20 studies (N = 216,365) were included in the analysis, which showed an overall pooled prevalence estimate of CMP and CP as 30.6 per 100 (95 % CI: 30.59, 30.69) and 27.9 per 100 (95 % CI: 27.68, 28.24) respectively. The heat map clustering analysis visualizes the similarity between CP and CMP. Moreover, a direct correlation was observed between the three disease conditions (namely CMP, CP, and VDD) and FokI VDR polymorphism (FF). Spearman’s correlation analyses with adjusted r2 revealed that there is a statistically significant interaction effect of the FF genotype and VDD on CMP (r2 = 0.19, p = 0.03), a marginally significant interaction effect of the ff genotype and VDD on CMP (r2 = 0.11, p = 0.08). VDD was also associated with increased CMP (r2 = 0.19, p = 0.028). The pooled estimates of the prevalence of CMP in this review were found to be high. Conclusion: FokI VDR gene polymorphism (FF) plays an important role in the relationship between VDD and CMP.

Association of the progesterone receptor gene polymorphism (PROGINS) with endometriosis: a meta-analysis

2014 ◽  
Vol 290 (5) ◽  
pp. 1015-1022 ◽  
Author(s):  
Noel Pabalan ◽  
Alice Salvador ◽  
Hamdi Jarjanazi ◽  
Denise Maria Christofolini ◽  
Caio Parente Barbosa ◽  
...  
Keyword(s):  
Progesterone Receptor ◽  
Gene Polymorphism ◽  
Meta Analysis ◽  
Receptor Gene ◽  
Receptor Gene Polymorphism ◽  
Progesterone Receptor Gene
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