Association between the leptin receptor gene polymorphism and lipoprotein profile in Chinese type 2 diabetes

2007 ◽  
Vol 1 (4) ◽  
pp. 259-265 ◽  
Author(s):  
Hongyun Lu ◽  
Jiazhong Sun ◽  
Yancheng Xu ◽  
Danhong Xie ◽  
Liao Sun ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Gene Polymorphism ◽  
Leptin Receptor ◽  
Receptor Gene ◽  
Lipoprotein Profile ◽  
Receptor Gene Polymorphism

scholarly journals Association of insulin resistance and leptin receptor gene polymorphism in type 2 diabetes mellitus

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Usha Adiga ◽  
Nandit Banawalikar ◽  
Sriprajna Mayur ◽  
Radhika Bansal ◽  
Nafeesath Ameera ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Gene Polymorphism ◽  
Leptin Receptor ◽  
Receptor Gene ◽  
Receptor Gene Polymorphism

β3 -Adrenergic receptor gene polymorphism and type 2 diabetes in a Caucasian population

2001 ◽  
Vol 3 (1) ◽  
pp. 47-51 ◽  
Author(s):  
A. M Oeveren van-Dybicz ◽  
H. E Vonkeman ◽  
M. A. M Bon ◽  
F. A. J. T. M Van Den Bergh ◽  
I Vermes
Keyword(s):  
Type 2 Diabetes ◽  
Gene Polymorphism ◽  
Adrenergic Receptor ◽  
Receptor Gene ◽  
Caucasian Population ◽  
Receptor Gene Polymorphism ◽  
Adrenergic Receptor Gene

scholarly journals The Role of Apa-I Vitamin D Receptor Gene Polymorphism in Type 2 Diabetes Mellitus

2021 ◽  
Vol 9 (A) ◽  
pp. 129-133
Author(s):  
Mutiara Indah Sari ◽  
Rusdiana Rusdiana ◽  
Milahayati Daulay
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Gene Polymorphism ◽  
Vitamin D Receptor ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Receptor Gene Polymorphism

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic metabolic syndrome caused by insulin secretion abnormalities, insulin action, or both. Gene polymorphism is a risk factor of T2DM. AIM: This study aims to see the role of Apa-I Vitamin D receptor gene polymorphism on T2DM. METHODS: This study was an analytic observational with a case–control approach, consisting of 70 T2DM patients and 70 healthy subjects as a control. Genotyping of the Apa-I Vitamin D receptor gene polymorphism was performed using the polymerase chain reactions-restriction fragment length polymorphisms method. The role of the Apa-I Vitamin D receptor gene polymorphism and the risk of T2DM were analyzed using the Chi-square test. RESULTS: The results showed that there was a significant association between codominant (TT genotype); dominant; recessive models of the Apa-I Vitamin D receptor gene polymorphism with the risk of T2DM (p < 0.05; odds ratio [OR] = 0.204, 95% confidence interval [CI] = 0.063–0.662; OR = 0.337, 95% CI = 0.113–1.004; OR = 0.367, 95% CI = 0.180–0.747, respectively), but not in codominant (GT genotype) and over-dominant models (p > 0.05). CONCLUSION: This study shows a role of the codominant (TT genotype); dominant; recessive models of the Apa-I Vitamin D receptor gene polymorphism on T2DM, but not in codominant (GT genotype) and over-dominant models.

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