scholarly journals Surveillance and Correlation of Antibiotic Consumption and Resistance of Acinetobacter baumannii complex in a Tertiary Care Hospital in Northeast China, 2003–2011

2013 ◽  
Vol 10 (4) ◽  
pp. 1462-1473 ◽  
Author(s):  
Jiancheng Xu ◽  
Zhihui Sun ◽  
Yanyan Li ◽  
Qi Zhou
2019 ◽  
Vol 41 (3) ◽  
pp. 59-62
Author(s):  
Jyotshna Sapkota ◽  
Manisha Sharma ◽  
Deepti Shrestha ◽  
Beena Jha

Introduction Acinetobacter calcoaceticus-Acinetobacter baumanni (ACB) complex is one of the commonest cause of hospital acquired and ventilator associated pneumonia. Multidrug resistant Acinetobacter species have become a matter of huge concern. This study was done to find out the antibiotic susceptibility pattern of Acinetobacter calcoaceticus-Acinetobacter baumanii complex from sputum samples. MethodsThis descriptive cross-sectional study was carried out in Clinical Microbiology laboratory from July 2018 to Jan 2019 after ethical approval. Acinetobacter calcoaceticus-Acinetobacter baumannii complex was identified on the basis of its microscopy and morphological characteristics followed by biochemical tests. Antibiotic sensitivity test of isolated pathogens was done using Muller Hinton Agar by Kirby-Bauer method. ResultsOf the 384 culture positive sputum specimen, 76 (19.80%) were Acinetobacter calcoaceticus-Acinetobacter baumannii complex. Most of the isolates were resistant to commonly used antibiotics, 72.36% of the isolates were multidrug resistance and 3.95% isolates were resistant to tigecycline. ConclusionThis study provides valuable information regarding prevalence of Acinetobacter calcoaceticus-Acinetobacter baumannii complex from sputum specimen. The alarming number of Multidrug resistance isolates is worrisome finding. Antibiotics like Tigecycline and Colistin which is still sensitive to isolates should be cautiously used only in MDR cases.


2018 ◽  
Vol 10 (02) ◽  
pp. 208-213 ◽  
Author(s):  
Jayanthi Siva Subramaniyan ◽  
Jeya Meenakshi Sundaram

Abstract CONTEXT: ICU shows increasing incidence of infection associated with the use of invasive procedures for the diagnostic purpose as well as the indiscriminate use of antibiotics. Pseudomonas aeruginosa and Acinetobacter species are "very successful" pathogen and the emergence of the Metallo-β-Lactamases (MBL) is becoming a therapeutic challenge. AIMS: To isolate the Nonfermenting Gram negative bacilli from the ICU samples. To identify the metallo betalactamase producers and to detect the bla gene presence among the Pseudomonas aeruginosa and Acinetobacter baumannii. SETTINGS AND DESIGN: The Nonfermenting Gram negative bacilli isolates from the ICU samples were taken over for 5 years (2009-2014) in a tertiary care hospital. METHODS AND MATERIALS: The isolates of Pseudomonas species and Acinetobacter species were confirmed by API analyser and processed according to standard procedures. Detection of the MBL producers were done by E strip method and subjected for bla gene detection by PCR method. RESULTS: In our study a total of 195 isolates of NFGNB were obtained from various ICU. Of these MBL producers, 26 % were Pseudomonas aeruginosa and 25 % were Acinetobacter baumannii. The subtypes of bla VIMMBL producing P.aeruginosa were 26%.The predominant gene coding for MBL activity in A.baumannii were found to be bla OXA gene 11.9%. The gene accession numbers were KF975367, KF975372. CONCLUSIONS: We have to control the development and dissemination of these superbugs among the ICU's.


2020 ◽  
Vol 26 (6) ◽  
pp. 681-684 ◽  
Author(s):  
Mehreen Gilani ◽  
Mahwish Latif ◽  
Mehwish Gilani ◽  
Nadia Saad ◽  
Maliha Ansari ◽  
...  

2015 ◽  
Vol 48 (2) ◽  
pp. S66
Author(s):  
Ong Yue Ling Rina ◽  
Seah Xue Fen Valerie ◽  
Chong Chia Yin ◽  
Tan Woon Hui Natalie ◽  
Thoon Koh Cheng

2016 ◽  
Vol 5 (3) ◽  
pp. 379-387 ◽  
Author(s):  
Saranya Vijayakumar ◽  
Radha Gopi ◽  
Priya Gunasekaran ◽  
Manjurekar Bharathy ◽  
Kamini Walia ◽  
...  

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