scholarly journals Clustering of Iron Oxide Nanoparticles into Poly(ethylene oxide)-block-poly(ε-caprolactone) Nanoassemblies as Ultrasensitive MRI Probes

2016 ◽  
Author(s):  
Adeline Hannecart ◽  
Dimitri Stanicki ◽  
Luce Vander Elst ◽  
Laetitia Mespouille ◽  
Robert N. Muller ◽  
...  
2019 ◽  
Vol 7 (30) ◽  
pp. 4692-4705 ◽  
Author(s):  
Adeline Hannecart ◽  
Dimitri Stanicki ◽  
Luce Vander Elst ◽  
Robert N. Muller ◽  
Annie Brûlet ◽  
...  

The present study reports the preparation of PEO-b-PCL polymer vesicles via a nanoprecipitation method and the loading of hydrophobically coated USPIO into the membrane of these nanovesicles, whose thickness was measured precisely by SANS.


RSC Advances ◽  
2016 ◽  
Vol 6 (33) ◽  
pp. 27798-27806 ◽  
Author(s):  
Ming Zhang ◽  
Turker Yilmaz ◽  
Ali Ozgur Boztas ◽  
Ozgur Karakuzu ◽  
Woo Young Bang ◽  
...  

Herein, a single-step, scalable approach for preparing a multifunctional, theranostic drug delivery system made out of paclitaxel, iron oxide nanoparticles, gold nanoparticles, and poly(ethylene oxide)-b-poly(ε-caprolactone) is reported.


2018 ◽  
Vol 9 (3) ◽  
pp. 362-371 ◽  
Author(s):  
L. Pichavant ◽  
M. J. López-González ◽  
A. Favereaux ◽  
V. Héroguez

DNA oligonucleotides (oligoDNAs) have been recently identified as a novel class of therapeutic tools for acting on the cancer-associated pain.


Nanomaterials ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1823
Author(s):  
Ivan Marić ◽  
Nataša Šijaković Vujičić ◽  
Anđela Pustak ◽  
Marijan Gotić ◽  
Goran Štefanić ◽  
...  

Magnetic polymer gels are a new promising class of nanocomposite gels. In this work, magnetic PEO/iron oxide nanocomposite hydrogels were synthesized using the one-step γ-irradiation method starting from poly(ethylene oxide) (PEO) and iron(III) precursor alkaline aqueous suspensions followed by simultaneous crosslinking of PEO chains and reduction of Fe(III) precursor. γ-irradiation dose and concentrations of Fe3+, 2-propanol and PEO in the initial suspensions were varied and optimized. With 2-propanol and at high doses magnetic gels with embedded magnetite nanoparticles were obtained, as confirmed by XRD, SEM and Mössbauer spectrometry. The quantitative determination of γ-irradiation generated Fe2+ was performed using the 1,10-phenanthroline method. The maximal Fe2+ molar fraction of 0.55 was achieved at 300 kGy, pH = 12 and initial 5% of Fe3+. The DSC and rheological measurements confirmed the formation of a well-structured network. The thermal and rheological properties of gels depended on the dose, PEO concentration and initial Fe3+ content (amount of nanoparticles synthesized inside gels). More amorphous and stronger gels were formed at higher dose and higher nanoparticle content. The properties of synthesized gels were determined by the presence of magnetic iron oxide nanoparticles, which acted as reinforcing agents and additional crosslinkers of PEO chains thus facilitating the one-step gel formation.


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