scholarly journals Effectiveness of a Novel Dentifrice Containing Stabilized Chlorine Dioxide, Sarkosyl, and Sodium Fluoride

2020 ◽  
Vol 8 (4) ◽  
pp. 122
Author(s):  
Srinivas Rao Mynenivenkatasatya ◽  
Howard Wang ◽  
William Cooley ◽  
Esmeralda Garcia-Smith ◽  
Jaiprakash Shewale ◽  
...  
Keyword(s):  
Sodium Fluoride ◽  
Chlorine Dioxide ◽  
In Vitro Study ◽  
Superior Performance ◽  
United States Pharmacopoeia ◽  
Fluoride Uptake ◽  
Assessment Tests ◽  
The Mean ◽  
Lauroyl Sarcosinate

This in vitro study evaluated the effectiveness of a novel dentifrice containing stabilized chlorine dioxide, sodium lauroyl sarcosinate (sarkosyl), and sodium fluoride in enhancing enamel fluoride uptake, remineralization, pellicle cleaning and inhibiting biofilm regrowth. Remineralization was measured by fluoride uptake and surface microhardness assessment tests. Artificial stains were removed and scored based on pellicle cleaning ratio. Biofilm regrowth was measured by counting colonies on the agar plates. All studies were conducted using bovine teeth specimens. The efficacy of Toothpaste C (CloSYS anticavity toothpaste) was compared with United States Pharmacopoeia Reference Dentifrice, Toothpaste B (discontinued CloSYS anticavity toothpaste formulation) and leading commercial toothpastes. The enamel fluoride uptake and remineralization by Toothpaste C was 96.1% to 303.3% and 38.0% to 102.4% higher than the tested toothpastes, respectively. The mean pellicle cleaning ratio of Toothpaste C was similar to American Dental Association Reference Material. Toothpaste C had a significant reduction in regrowth of the oral polymicrobial biofilm compared to the control. All tested toothpastes contained 0.24% sodium fluoride. Toothpaste C exhibited significantly superior performance towards fluoride uptake and remineralization compared to the tested toothpastes. Therefore, toothpaste ingredients other than sodium fluoride accounted for the enhanced fluoride uptake and remineralization.

scholarly journals Shear bond strength evaluation of bonded molar tubes on fluorotic molars

2012 ◽  
Vol 83 (1) ◽  
pp. 152-157 ◽  
Author(s):  
Erika L. Silva-Benítez ◽  
Veronica Zavala-Alonso ◽  
Gabriel A. Martinez-Castanon ◽  
Juan P. Loyola-Rodriguez ◽  
Nuria Patiño-Marin ◽  
...  
Keyword(s):  
Bond Strength ◽  
Shear Bond Strength ◽  
Dental Fluorosis ◽  
In Vitro Study ◽  
Mean Value ◽  
Fixed Appliance ◽  
Adhesive Remnant Index ◽  
The Mean ◽  
Electronic Microscope

Abstract Objective: To study the shear bond strength (SBS), sites of failure, and micromorphology of bonded molar tubes used on teeth affected by dental fluorosis. Materials and Methods: This in vitro study included 140 first molars classified according to Dean's index for dental fluorosis. Samples were divided into seven groups: (1) healthy teeth etched for 15 seconds, (2) teeth with moderate fluorosis (MOF) etched for 15 seconds, (3) teeth with MOF etched for 150 seconds, (4) teeth with MOF microabrasion etched for 15 seconds, (5) teeth with severe fluorosis (SEF) etched for 15 seconds, (6) teeth with SEF etched for 150 seconds, and (7) teeth with SEF microabrasion etched for 15 seconds. All samples were incubated and were then submitted to the SBS test and evaluated with the modified adhesive remnant index (ARI) and analyzed by using a scanning electronic microscope. Results: The SBS mean value for healthy enamel was 20 ± 10.2 MPa. For the group with MOF, the etched 150-second mean value was the highest (19 ± 7.6 MPa); for the group with SEF treated with microabrasion and etched for 15 seconds, the mean value was (13 ± 4.1 MPa). Significant differences (P ≤ .05) were found in the ARI between healthy and fluorosed groups. Conclusions: Fluorotic enamel affects the adhesion of bonded molar tubes. The use of overetching in cases of MOF and the combination of microabrasion and etching in SEF provides a suitable adhesion for fixed appliance therapy.

scholarly journals An in vitro comparison of the force decay generated by different commercially available elastomeric chains and NiTi closed coil springs

2007 ◽  
Vol 21 (1) ◽  
pp. 51-57 ◽  
Author(s):  
Ana Cristina Soares Santos ◽  
André Tortamano ◽  
Sandra Regina Frazatto Naccarato ◽  
Gladys Cristina Dominguez-Rodriguez ◽  
Julio Wilson Vigorito
Keyword(s):  
Artificial Saliva ◽  
Testing Machine ◽  
In Vitro Study ◽  
Original Length ◽  
Force Decay ◽  
Decay Pattern ◽  
The Mean ◽  
Initial Force ◽  
Elastomeric Chains

This in vitro study was designed to compare the forces generated by commercially available elastomeric chains and NiTi closed coil springs, and to determine their force decay pattern. Forty elastomeric chains and forty NiTi closed coil springs were divided into 4 groups according to the following manufacturers: (1) Morelli®, (2) Abzil®, (3) TP Orthodontics® and (4) American Orthodontics®. The specimens were extended to twice their original length and stored in artificial saliva at 37°C. Initial force was measured by means of an Instron universal testing machine and then at 1, 4, 7, 14, 21, and 28 days. The results revealed that the elastomeric chains delivered a mean initial force of 347 g for Morelli®, 351 g for American Orthodontics®, 402 g for Abzil®, and 404 g for TP Orthodontics®. The NiTi closed coil springs generated a mean initial force of 196 g for American Orthodontics®, 208 g for TP Orthodontics®, 216 g for Abzil®, and 223 g for Morelli®. The mean percentage of force decay observed after 28 days for the elastomeric chains was 37.4% for TP Orthodontics®, 48.1% for American Orthodontics®, 65.4% for Morelli®, and 71.6% for Abzil®. After 28 days, the NiTi closed coil springs presented a mean percentage of force decay of 22.6% for American Orthodontics®, 29.8% for Abzil®, 30.6% for Morelli®, and 45.8% for TP Orthodontics®. At the end of the study, significant differences were observed between the elastomeric chains and the NiTi closed coil springs. The results indicated that the studied NiTi closed coil springs are more adequate for dental movement than the elastomeric chains.

scholarly journals Evaluation of Gaps or Voids Occurring in Roots Filled with Three Different Sealers

2010 ◽  
Vol 04 (02) ◽  
pp. 101-109 ◽  
Author(s):  
Melek Akman ◽  
Serhan Akman ◽  
Oznur Derinbay ◽  
Sema Belli
Keyword(s):  
In Vitro Study ◽  
Gutta Percha ◽  
Rotary Instruments ◽  
Single Cone ◽  
Ah Plus ◽  
Root Dentin ◽  
The Mean ◽  
Free Interfaces ◽  
Niti Rotary Instruments

Objectives: The purpose of this in vitro study was to evaluate gaps or voids occurring in roots filled with three different sealers.Methods: Thirty extracted human single-rooted teeth were decoronated, instrumented using NiTi rotary instruments, divided into three groups (n=10 per group) and obturated with one of the following: Epiphany with Resilon, MetaSEAL with gutta-percha or AH Plus with gutta-percha using the match-taper single-cone technique. After storage for one week in 100% humidity at 37°C, the teeth were horizontally sectioned (n=10). Photographs were taken from the coronal, median and apical parts of the roots using a stereomicroscope at 10X magnification, and the images were then transferred to a computer. The mathematical method known as the ‘Affine Transformation’ was used for the transformation of pixel coordinates to ground coordinates in the Netcad Software program. The mean areas (μm2) of the gaps between the sealer and root dentin or gutta percha/resilon and the gaps between the sealer and/or voids inside the sealer mass were measured, scored on a 0-3 scale and statistically analyzed with the Kruskal-Wallis test.Results: The mean total area of gaps or voids for each sealer was 4631.80 μm2 for the Epiphany- Resilon, 3826.80 μm2 for the MetaSEAL-gutta-percha and 31334 μm2 for the AH Plus-gutta-percha. The MetaSEAL-gutta-percha group showed more gap or void-free interfaces. No significant differences were found among the sealers in the scores for the gap areas (P<.05), and the MetaSEAL showed similar interfaces with Epiphany.Conclusions: No significant differences in the mean areas of gaps or voids were found among the tested resin-based sealers. (Eur J Dent 2010;4:101-109)

scholarly journals Inhibition of Demineralization at Restoration Margins of Z100 and Tetric EvoCeram Bulk Fill in Dentin and Enamel

2019 ◽  
Vol 6 (2) ◽  
pp. 36
Author(s):  
Cristina Leon-Pineda ◽  
Kevin Donly
Keyword(s):  
Light Microscopy ◽  
Polarized Light ◽  
In Vitro Study ◽  
The Other ◽  
Solution Ph ◽  
Class V ◽  
The Mean ◽  
Student’S T ◽  
Student’S T Test

Recurrent caries is still considered the main reason restorations need to be replaced. There are different materials available now that promise to reduce the possibility of recurrent caries by releasing fluoride and inhibiting restoration marginal caries. The purpose of this in vitro study was to evaluate the demineralization inhibition potential of a non-fluoride-releasing resin (Z100TM 3M, St. Paul, MN, USA) and a glass containing resin-based composite (Tetric EvoCeram Bulk Fill, Ivoclar/Vivadent AG, Schaan, Liechtenstein), which contains fluoride. Class V preparations were placed on 22 premolars; the gingival margin was below the cementoenamel junction and the occlusal margin was placed above the cemento-enamel junction. Ten teeth were randomly selected to be restored with Z100 while the other 10 were restored with Tetric EvoCeram Bulk Fill. Both groups were restored following manufacturer’s instructions. All teeth had an acid resistant varnish placed within one millimeter of the preparation margins. Both groups were placed in artificial caries challenge solution (pH 4.4). At the end of the 4 days; 100 µm buccolingual sections were obtained for each tooth; these were photographed under polarized light microscopy and the demineralized areas adjacent to the restorations were measured and quantified. The mean (±S.D.) area (µm2) of demineralization from the occlusal margin (enamel) and dentin margin were: Z100 2781.889 ± 1045.213; 3960.455 ± 705.964 and for Tetric EvoCeram Bulk Fill 1541.545 ± 1167.027; 3027.600 ± 512.078. Student’s t-test indicated that there was significantly less enamel and dentin demineralization adjacent to Tetric EvoCeram Bulk Fill compared to Z100; there was significantly less demineralization in enamel compared to dentin in both Tetric EvoCeral Bulk Fill and Z100. Tetric EvoCeram Bulk Fill performed better inhibiting demineralization at restoration margins when compared to Z100 and provided better demineralization inhibition in enamel than cementum/dentin.

Effect of Different Intermediary Bases on Microleakage of a Restorative Material in Class II Box Cavities of Primary Teeth

2017 ◽  
Vol 40 (2) ◽  
pp. 82-87 ◽  
Author(s):  
Faika Y. Abdelmegid ◽  
Fouad S. Salama ◽  
Waleed M. Al-Mutairi ◽  
Saud K. Al-Mutairi ◽  
Sultan O. Baghazal
Keyword(s):  
Primary Teeth ◽  
In Vitro Study ◽  
Class Ii ◽  
Positive Control ◽  
Negative Control ◽  
The Other ◽  
Control Groups ◽  
Significant Difference ◽  
The Mean

Introduction The aim of this in vitro study was to assess and compare the effect of different intermediary bases on microleakage between tooth and a nanocomposite interface in Class II box cavities in primary teeth. Methods Standard Class II box cavities were prepared in 52 primary molars and randomly divided into 9 groups according to the intermediary base used (Multicore Flow, Fuji II LC, SDR, Smart Dentin Replacement, and Biodentine). All specimens were subjected to thermocycling and prepared for microleakage testing and evaluation. Results There was significant difference in the mean ranks of microleakage between the 9 groups, which was observed in the gingival side (p<0.0001) and the occlusal side (p<0.0001). The mean ranks microleakage was significantly higher with experimental SDR, experimental Multicore Flow, and positive control materials when compared with the other 6 groups. The microleakage mean ranks were statistically significantly lower in experimental Fuji II LC, experimental Biodentine, and all negative control groups when compared with the other 3 groups. Conclusions Microleakage is affected by the application of intermediate material. Experimental Biodentine and Fuji II LC showed the lowest microleakage while experimental SDR and experimental Multicore Flow showed the highest microleakage.

scholarly journals Evaluation of marginal fit of two allceramic copings with two finish lines

2012 ◽  
Vol 06 (02) ◽  
pp. 163-168 ◽  
Author(s):  
Gulce Subasi ◽  
Nilgun Ozturk ◽  
Inan Ozgur ◽  
Nalan Bozogullari
Keyword(s):  
Stainless Steel ◽  
Analysis Of Variance ◽  
In Vitro Study ◽  
Finish Line ◽  
Marginal Fit ◽  
Luting Agent ◽  
All Ceramic ◽  
The Mean ◽  
Line Design

ABSTRACTObjectives: This in-vitro study investigated the marginal fit of two all-ceramic copings with 2 finish line designsMethods: Forty machined stainless steel molar die models with two different margin designs (chamfer and rounded shoulder) were prepared. A total of 40 standardized copings were fabricated and divided into 4 groups (n=10 for each finish line-coping material). Coping materials tested were IPS e.max Press and Zirkonzahn; luting agent was Variolink II. Marginal fit was evaluated after cementation with a stereomicroscope (Leica MZ16). Two-way analysis of variance and Tukey-HSD test were performed to assess the influence of each finish line design and ceramic type on the marginal fit of 2 all-ceramic copings (α =.05) Results: Two-way analysis of variance revealed no statistically significant differences for marginal fit relative to finish lines (P=.362) and ceramic types (P=.065)Conclusion: Within the limitations of this study, both types of all-ceramic copings demonstrated that the mean marginal fit was considered acceptable for clinical application (≤120 μm). (Eur J Dent 2012;6:163-168)

scholarly journals Influence of Orthodontic Anchor Screw Anchorage Method on the Stability of Artificial Bone: An In Vitro Study

Materials ◽  
2020 ◽  
Vol 13 (14) ◽  
pp. 3205 ◽  
Author(s):  
Seen-Young Kang ◽  
Ji-Min Yu ◽  
Hyoung-Sik Kim ◽  
Jun-Seok Lee ◽  
Chan-Mi Yeon ◽  
...  
Keyword(s):  
In Vitro Study ◽  
Automatic Device ◽  
Insertion Torque ◽  
Artificial Bone ◽  
Artificial Bones ◽  
Significant Difference ◽  
The Mean ◽  
The Stability ◽  
Torque Values

This study aims to compare the torque values for various lengths of the titanium-based orthodontic anchor screw (OAS), different anchorage methods and varying artificial bone densities after predrilling. Furthermore, the effects of these parameters on bone stability are evaluated. A total of 144 OASs were prepared with a diameter of 1.6 mm and heights of 6, 8 and 10 mm. Artificial bones were selected according to their density, corresponding to Grades 50, 40 and 30. Torque values for the automatic device and manual anchorage methods exhibited a statistically significant difference for the same-sized OAS, according to the bone density of the artificial bones (p < 0.05). However, when insertion torque was at the maximum rotations, there was no significant difference in the torque values for the Grade 30 artificial bone (p > 0.05). When the torque values of both anchorage methods were statistically compared with the mean difference for each group, the results of the manual anchorage method were significantly higher than those of the automatic device anchorage method (p < 0.05). A statistically significant difference was observed in the bone stability resulting from different OAS anchorage methods and artificial bone lengths. These findings suggest that the automatic anchorage method should be used when fixing the OAS.

scholarly journals Opposite Effects of Single-Dose and Multidose Administration of the Ethanol Extract of Danshen on CYP3A in Healthy Volunteers

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Furong Qiu ◽  
Jian Jiang ◽  
Yueming Ma ◽  
Guangji Wang ◽  
Chenglu Gao ◽  
...  
Keyword(s):  
Single Dose ◽  
Healthy Volunteers ◽  
Plasma Concentrations ◽  
In Vitro Study ◽  
Ethanol Extract ◽  
Tanshinone Iia ◽  
Open Label ◽  
The Mean

The aim of this study was to investigate the effect of single- and multidose administration of the ethanol extract of danshen on in vivo CYP3A activity in healthy volunteers. A sequential, open-label, and three-period pharmacokinetic interaction study design was used based on 12 healthy male individuals. The plasma concentrations of midazolam and its metabolite 1-hydroxymidazolam were measured. Treatment with single dose of the extract caused the meanCmaxof midazolam to increase by 87% compared with control. After 10 days of the danshen extract intake, the mean AUC0–12,Cmax, andt1/2of midazolam were decreased by 79.9%, 66.6%, and 43.8%, respectively. The mean clearance of midazolam was increased by 501.6% compared with control. The in vitro study showed that dihydrotanshinone I in the extract could inhibit CYP3A, while tanshinone IIA and cryptotanshinone could induce CYP3A. In conclusion, a single-dose administration of the danshen extract can inhibit intestinal CYP3A, but multidose administration can induce intestinal and hepatic CYP3A.

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