scholarly journals Antibacterial Additives in Epoxy Resin-Based Root Canal Sealers: A Focused Review

2019 ◽  
Vol 7 (3) ◽  
pp. 72 ◽  
Author(s):  
Alexander Brezhnev ◽  
Prasanna Neelakantan ◽  
Ray Tanaka ◽  
Sergey Brezhnev ◽  
George Fokas ◽  
...  

Dental materials used in root canal treatment have undergone substantial improvements over the past decade. However, one area that still remains to be addressed is the ability of root canal fillings to effectively entomb, kill bacteria, and prevent the formation of a biofilm, all of which will prevent reinfection of the root canal system. Thus far, no published review has analysed the literature on antimicrobial additives to root canal sealers and their influence on physicochemical properties. The aim of this paper was to systematically review the current literature on antimicrobial additives in root canal sealers, their anti-fouling effects, and influence on physicochemical properties. A systematic search was performed in two databases (PubMed and Scopus) to identify studies that investigated the effect of antimicrobial additives in epoxy resin-based root canal sealers. The nature of additives, their antimicrobial effects, methods of antimicrobial testing are critically discussed. The effects on sealer properties have also been reviewed. A total of 31 research papers were reviewed in this work. A variety of antimicrobial agents have been evaluated as additives to epoxy resin-based sealers, including quaternary ammonium compounds, chlorhexidine, calcium hydroxide, iodoform, natural extracts, antibiotics, antifungal drugs, and antimicrobial agent-functionalised nanoparticles. Antimicrobial additives generally improved the antimicrobial effect of epoxy resin-based sealers mainly without deteriorating the physicochemical properties, which mostly remained in accordance with ISO and ANSI/ADA specifications.

Author(s):  
Gabriela Cardoso Ferreira ◽  
Lucas Siqueira Pinheiro ◽  
Júlia Silveira Nunes ◽  
Roberta Almeida Mendes ◽  
Cláudia Daniela Schuster ◽  
...  

2017 ◽  
Vol 31 (0) ◽  
Author(s):  
Rafael Verardino de CAMARGO ◽  
Yara Terezinha Corrêa SILVA-SOUSA ◽  
Rodrigo Presotto Ferreira da ROSA ◽  
Jardel Francisco MAZZI-CHAVES ◽  
Fabiane Carneiro LOPES ◽  
...  

2021 ◽  
Vol 2 (1) ◽  
pp. 14-25
Author(s):  
Musliana Mustaffa

The use of bioceramic root canal sealers in endodontics is a promising approach because of the advantages such as improved flow properties, biocompatible and could promote the formation of hard tissue. Due to the recent technology and limited scientific evidence, the effectiveness of bioceramic root canal sealers remains unclear. This article focuses on the physicochemical properties, biocompatibility, biomineralisation, retreatability, 3D obturation and current practice of using bioceramic root canal sealers. The relevant articles for this review were searched manually from Google Scholar and PubMed using keywords ‘bioceramic root filling material AND endodontics’, ‘bioceramic root canal sealers AND endodontics’, ‘cytotoxicity AND bioceramic root canal sealers’, ‘bioceramic root canal sealers AND physicochemical properties’, ‘biomineralisation AND bioceramic root canal sealers’ and ‘retreatment efficacy AND bioceramic root filling materials’. Since the clinical data concerning the obturation with bioceramic root canal sealers is lacking, the selection of materials should be made based on the available scientific evidence, individual cases, material availability and operator’s preference.


2014 ◽  
Vol 30 ◽  
pp. e61-e62
Author(s):  
G.B. Leoni ◽  
J.F.M. Chaves ◽  
B.M. Crozeta ◽  
V.L.C. Araújo ◽  
R.P.F. Rosa ◽  
...  

2006 ◽  
Vol 53 (2) ◽  
pp. 104-112 ◽  
Author(s):  
Mirjana Vujaskovic ◽  
Branka Radosavljevic

All root canal sealers should have antimicrobial activity so that they could act against any remaining bacteria after root canal obturation. The aim of this study was to evaluate the antimicrobial activity of five root canal sealers: AH26, a resin based paste; Apexit, calcium hydroxide based paste; Endomethasone and Tubliseal, zinc oxide eugenol based materials and Ketac Endo Aplicap, glass ionomer based sealer. Matherials And Methods: Antimicrobial activity was tested against S. mutans 70C and L.casei ATCC 27773 using ADT (agar diffusion inhibitory test) on TYC SB, blood and MRS agars. Freshly prepared paste or cement was placed in grooves of 4 mm in diameter in agar plates. Prepared agar plates were incubated at 37?C in GAS PAC system for 24hours. The antimicrobial effect was determined according to the diameter of growth inhibition zone around tested materials. Three measurements were done for each material and values were recorded in millimeters. Statistical analysis was done using Mann Whitney test. The results confirmed that epoxy resin and zinc oxide eugenol based sealers had the greatest antimicrobial effect. Calcium hydroxide and glass ionomer based sealers showed significantly lower antimicrobial activity compared to AH26, Endomethasone and Tubliseal. Conclusion: The greatest antimicrobial activity was found for epoxy resin based sealer (AH26) for both tested microorganisms.


2017 ◽  
Vol 3 (2) ◽  
pp. 7-12 ◽  
Author(s):  
Ali Monajemzadeh ◽  
Sina Ahmadi ◽  
Sajad Aslani ◽  
Batool Sadeghi-Nejad ◽  
◽  
...  

Materials ◽  
2021 ◽  
Vol 14 (24) ◽  
pp. 7594
Author(s):  
Zhejun Wang ◽  
Ya Shen ◽  
Markus Haapasalo

Microbes are prevalent in the root canals of necrotic teeth, and they are the cause of primary and post-treatment apical periodontitis. Bacteria can dwell within the infected root canal system as surface-adherent biofilm structures, which exhibit high resistance to antimicrobial agents. Bioceramic materials, with their biocompatible nature and excellent physico-chemical properties, have been widely used in dental applications, including endodontics. This review focuses on the application of bioceramic technology in endodontic disinfection and the antibiofilm effects of endodontic bioceramic materials. Different bioceramic materials have shown different levels of antibiofilm effects. New supplements have emerged to potentially enhance the antibiofilm properties of bioceramics aiming to achieve the goal of microbial elimination in the root canal system.


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