scholarly journals Effects of Amorphous Calcium Phosphate Administration on Dental Sensitivity during In-Office and At-Home Interventions

2018 ◽  
Vol 6 (4) ◽  
pp. 52 ◽  
Author(s):  
Giacomo Oldoini ◽  
Antonino Bruno ◽  
Anna Genovesi ◽  
Luca Parisi

Background. Tooth bleaching is the most frequently employed whitening procedure in clinics. The major side effect of tooth bleaching is dental sensitivity during and after the treatment. Here, we evaluated whether the administration of amorphous calcium phosphate (ACP), during in-office and at-home procedures may impact on dental sensitivity. Methods. Eighty patients, responding to the study requirements were enrolled according to the following criteria. Group 1 (n = 40), received in-office, 10% ACP prior to 30% professional hydrogen peroxide application. The whitening procedure continued at home using 10% carbamide peroxide with 15% ACP for 15 days. Group 2 (n = 40) received only 30% hydrogen peroxide application and continued the whitening procedures at home, using 10% carbamide hydroxide, without ACP- Casein phosphopeptides (CPP), for 15 days. Dental sensitivity was recorded with a visual analogue scale (VAS) at baseline, immediately after, and at 15 days after treatment in the two groups. Results. We observed that patients receiving ACP in the bleaching mixture experienced decreased dental sensitivity (* p ≤ 0.05), as detected by VAS scale analysis immediately following the procedures. Patients receiving ACP-CPP during at-home procedures showed a statistically significant (*** p ≤ 0.0001) reduction of dental sensitivity. Conclusions. We demonstrated that ACP-CPP administration, while exerting the same whitening effects as in control subjects receiving potassium fluoride (PF), had an impact on the reduction of dental sensitivity, improving patient compliance.

2009 ◽  
Vol 79 (1) ◽  
pp. 122-126 ◽  
Author(s):  
Virna Cavalcante Patusco ◽  
Gil Montenegro ◽  
Marcos Augusto Lenza ◽  
Adilson Alves de Carvalho

Abstract Objective: To test the hypothesis that there is no difference between the action of at-home and in-office vital bleaching on the shear bond strength of metallic brackets bonded with composite resin 24 hours after bleaching. Materials and Methods: Forty-five human upper premolars were randomly divided into three groups: (1) control, (2) 10% carbamide peroxide at-home bleached, and (3) 35% hydrogen peroxide in-office bleached. Twenty-four hours after bleaching the teeth were pumiced, bonded with metallic brackets, and stored in distilled water. One day after bonding the shear bond strength of the brackets was determined. Results: The mean shear bond strength of Group 1 (control) and Group 2 (carbamide peroxide bleached) were not statistically different. Group 3 (hydrogen peroxide bleached) had a significantly lower mean shear bond strength than Group 1 and Group 2. Conclusions: The hypothesis is rejected. Use of 10% carbamide peroxide bleaching does not significantly alter shear bond strength values. On the other hand, use of 35% hydrogen peroxide bleaching significantly reduces these values and diminishes the amount of resin remnant on the tooth surface after bracket debonding.


2021 ◽  
pp. 1-10
Author(s):  
Ahmed Sleibi ◽  
Anwar R. Tappuni ◽  
Aylin Baysan

Different formulas of topical fluoride have been used to manage root carious lesions. This clinical trial aimed to investigate the efficacy of a dental varnish containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride compared with fluoride alone in reversing/arresting root caries in xerostomic patients over 1 year. A total of 80 patients (age range 45–92 years) with primary root caries (<i>n</i> = 184 root carious lesions) and unstimulated salivary flow rate of &#x3c;0.2 mL/min were randomly allocated to receive either dental varnish containing CPP-ACP and 5% fluoride (group 1: MI varnish; GC, Japan) (<i>n</i> = 41, 83 lesions), or dental varnish with 5% fluoride alone (group 2: NUPRO White; Dentsply, USA) (<i>n</i> = 39, 101 lesions). Clinical assessments with Severity Index (SI) for root caries, DIAGNOdent measurements, and varnish application were carried out at baseline, 3, 6, and 12 months. Standard oral hygiene instructions with 1,450 ppm fluoride toothpastes were provided for both groups. After 3 months, 63.9% (<i>n</i> = 46) of root caries in group 1 became hard (SI: 0) compared with 39.3% (<i>n</i> = 35) in group 2 (<i>p</i> &#x3c; 0.01). After 6 and 12 months, the differences in SI were insignificant (group 1, <i>n</i> = 60, 83.3%) (group 2, <i>n</i> = 66, 74.2%) (<i>p</i> = 0.36), and (group 1, <i>n</i> = 60, 89.6%) (group 2, <i>n</i> = 67, 81.7%, <i>n</i> = 1 soft, 1.2%) (<i>p</i> = 0.29), respectively. In both groups, noncavitated leathery lesions were more likely to become hard when compared to the cavitated root caries. A significant decrease in plaque index, surface roughness, lesion dimension, and DIAGNOdent readings with a significant increase in lesion distance from the gingival margin was reported in both groups (<i>p</i> &#x3c; 0.05). This study has provided evidence that fluoride dental varnish either with or without calcium and phosphate has the potential to arrest/reverse root caries, especially noncavitated lesions for patients with xerostomia.


Author(s):  
Marcela Alvarez FERRETTI ◽  
Matheus KURY ◽  
Beatriz Curvello de MENDONÇA ◽  
Marcelo GIANNINI ◽  
Vanessa CAVALLI ◽  
...  

ABSTRACT Tooth bleaching is one of the most conservative aesthetic techniques. At-home and in-office bleaching may be performed, as well as the combination of both techniques. As this combination may be done in different manners, distinct orders of combinations were proposed in this report. A 24 years-old man, whose upper central incisor and canine shades were A2 and A3 respectively, was initially treated by chair-side with 40-min application of 40% hydrogen peroxide (HP) for two sessions. Afterwards, an two-week overnight at-home bleaching was performed with 10% carbamide peroxide (CP). The shade of upper central incisors changed to 1M1 and canine was B1. Conversely, a 30 years-old woman was firstly conducted with at-home bleaching (overnight 4-weeks 10% CP) and, subsequently, with a single appointment of in-office bleaching for 45 minutes (35% HP). The shade of her upper central incisor changed from A1 to 0.5M1 and the upper canine from A3 to B1. The VITA classical (A1-D4) shade guide and VITA Bleached guide 3D-MASTER were used to determine the tooth color during the treatments. In both bleaching treatments, patients reported no significant tooth sensitivity and the final outcomes met their expectation.


2020 ◽  
Vol 27 (2) ◽  
Author(s):  
Nazila Ameli ◽  
◽  
Niloofar Kianvash Rad ◽  
Farzane Nikpour ◽  
Raheb Ghorbani ◽  
...  

Bleaching is a well-known esthetic dental treatment performed to lighten the tooth shade. Among different cosmetic dental procedures, including direct and indirect tooth-colored restorations, bleaching is likely the most conservative approach. Bleaching has been accepted well by patients and proven as a safe and effective approach. Objective: Tooth bleaching can be conducted at home or in offices. This study was performed to compare the enamel microhardness before bleaching and one and eight weeks after the application of different bleaching agents. Methods: Forty human premolars were randomly divided into four groups, and their buccal surface underwent a Vickers microhardness test before and after bleaching. Bleaching was performed with 40% hydrogen peroxide (HP) in-office bleaching agent (n = 10), 15% HP at-home bleaching agent (n = 10), and 15% carbamide peroxide (CP) at-home bleaching agent (n = 10) for two weeks. Ten samples were stored in artificial saliva and set as the control group. The microhardness of the samples was measured again one and eight weeks after bleaching. Results: The microhardness significantly decreased in the four groups one week after bleaching. Conclusion: The enamel microhardness was temporarily decreased by in-office bleaching. However, the microhardness increased with time and returned to the baseline value. Although the enamel microhardness initially reduced, it increased eight weeks after 15% CP at-home bleaching agent was applied.


2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Mohammad E. Rokaya ◽  
Khaled Beshr ◽  
Abeer Hashem Mahram ◽  
Samah Samir Pedir ◽  
Kusai Baroudi

Objectives. Extra radicular diffusion of hydrogen peroxide associated with intracoronal teeth bleaching was evaluated.Methods. 108 intact single rooted extracted mandibular first premolars teeth were selected. The teeth were instrumented with WaveOne system and obturated with gutta percha and divided into four groups (n=27) according to the bleaching materials used. Each main group was divided into three subgroups (n=9) according to the time of extra radicular hydrogen peroxide diffusion measurements at 1, 7, and 14 days: group 1 (35% hydrogen peroxide), group 2 (35% carbamide peroxide), group 3 (sodium perborate-30% hydrogen peroxide mixture), and group 4 (sodium perborate-water mixture). Four cemental dentinal defects were prepared just below the CEJ on each root surface. The amount of hydrogen peroxide that leached out was evaluated after 1, 7, and 14 days by spectrophotometer analysis. The results were analyzed using the ANOVA and Tukey’s test.Results. Group 1 showed highest extra radicular diffusion, followed by group 3 and group 2, while group 4 showed the lowest mean extra radicular diffusion.Conclusion. Carbamide peroxide and sodium perborate-water mixture are the most suitable bleaching materials used for internal bleaching due to their low extra radicular diffusion of hydrogen peroxide.


2009 ◽  
Vol 79 (1) ◽  
pp. 117-121 ◽  
Author(s):  
Tancan Uysal ◽  
Mustafa Ulker ◽  
Gulsen Akdogan ◽  
Sabri Ilhan Ramoglu ◽  
Esra Yilmaz

Abstract Objective: To evaluate the shear bond strength and fracture mode difference between amorphous calcium phosphate (ACP)–containing adhesive and conventional resin-based composite material used as an orthodontic lingual retainer adhesive. Materials and Methods: Forty crowns of extracted lower human incisors were mounted in acrylic resin, leaving the buccal surface of the crowns parallel to the base of the molds. The teeth were randomly divided into two groups: experimental and control, containing 20 teeth each. Conventional lingual retainer composite (Transbond-LR, 3M-Unitek) and ACP-containing orthodontic adhesive (Aegis-Ortho) were applied to the teeth surface by packing the material into the cylindrical plastic matrices with a 2.34-mm internal diameter and a 3-mm height (Ultradent) to simulate the lingual retainer bonding. For shear bond testing, the specimens were mounted in a universal testing machine, and an apparatus (Ultradent) attached to a compression load cell was applied to each specimen until failure occurred. The shear bond data were analyzed using Student's t-test. Fracture modes were analyzed by χ2 test. Results: The statistical test showed that the bond strengths of group 1 (control Transbond-LR, mean: 24.77 ± 9.25 MPa) and group 2 (ACP-containing adhesive, mean: 8.49 ± 2.53 MPa) were significantly different from each other. In general, a greater percentage of the fractures were adhesive at the tooth-composite interface (60% in group 1 and 55% in group 2), and no statistically significant difference was found between groups. Conclusion: The ACP-containing Aegis-Ortho adhesive resulted in a significant decrease in bond strength to the etched enamel surface.


2013 ◽  
Vol 07 (01) ◽  
pp. 055-060 ◽  
Author(s):  
Mehmet Akin ◽  
Sertac Aksakalli ◽  
Faruk Ayhan Basciftci ◽  
Abdullah Demir

ABSTRACTObjective: The purpose of this study was to determine the effect of 10% carbamide peroxide and 38% hydrogen peroxide bleaching agents on the shear bond strength of orthodontic brackets using self-etching primer systems.Methods: Forty five freshly extracted human premolar teeth were randomly divided into 3 groups of 15 teeth each: control (group 1), 10% carbamide peroxide at-home bleached (group 2), and 38% hydrogen peroxide in-office bleached (group 3). Three weeks later, all brackets were bonded using a self-etching primer system. The shear bond strength of these brackets was measured and recorded in MPa. Adhesive remnant index (ARI) scores were determined after the brackets failed. Data were analyzed using Kruskal- Wallis test, pairwise comparisons were made using the Mann-Whitney U test and ARI scores were analyzed using a chi-square test at a significance level of P<.05.Results: The shear bond strengths of group 1 (mean: 17.7 ± 9.7 MPa) were significantly higher (P<.05) than those of group 3 (mean: 9.9 ± 5.4 MPa). No significant differences were found between group 2 (mean: 12.3 ± 4.7) and either group 1 or group 3 (P>.05). ARI scores did not differ significantly among the 3 groups.Conclusions: The use of 10% carbamide peroxide bleaching does not significantly reduce shear bond strength values. In contrast, use of 38% hydrogen peroxide bleaching significantly reduces these values. (Eur J Dent 2013;7:55-60)


2018 ◽  
Vol 21 (2) ◽  
pp. 157
Author(s):  
André Luiz Fraga Briso ◽  
Marjorie Oliveira Gallinari ◽  
Francine Benetti ◽  
Diego Valentim ◽  
Carlos Roberto Emerenciano Bueno ◽  
...  

<p><strong>Objective</strong>: The at-home bleaching technique leads to the intimate contact of the bleaching gel with gingival tissues, so this study evaluated the immediate inflammatory response, through the edemogenic test, induced by at-home bleaching gels of 10% carbamide peroxide with different desensitizing agents, the quantification of hydrogen peroxide released and bleaching gels pH. <strong>Material</strong> <strong>and</strong> <strong>Methods</strong>: Forty-eight rats were divided into groups (n=12): CTRL-control group, WP-Whiteness Perfect 10% (FGM Produtos Odontológicos, Joinville, SC, Brazil), OPA-Opalescence 10% (Ultradent Products Inc., South Jordan, IT, USA), and PB-Power Bleaching (BM4, Palhoça, SC, Brazil). For the edemogenic test, all rats received an intravenous injection of Evan's Blue; after 30 min, 0.2 mL of each bleaching gels was injected into the subcutaneous tissue of the rats, and the results of the vascular permeability were assessed after 3 and 6h. The amount of HP released and pH of each product was also determined. Data were submitted to statistical test (<em>p</em>&lt;0.05). <strong>Results</strong>: At 3h, the PB showed higher vascular permeability than the other groups. At 6h, the PB produced similar vascular permeability than WHI, and higher than OPA and CTRL groups. The OPA group had a higher vascular permeability at 6h compared to 3h; there is no difference in other groups. The PB group had higher HP concentrations than the other groups. <strong>Conclusion</strong>: In general, the PB caused a more considerable amount of inflammatory edema and higher amount of HP released. This results suggesting that these bleaching gels cause greater aggression in soft gingival tissues that eventually ends up in contact with bleaching products</p><p> </p><p class="CorpoA"><strong>Keywords</strong><strong></strong></p><p class="CorpoA">Tooth bleaching; Carbamide peroxide; Hydrogen peroxide; Capillary permeability.</p>


2021 ◽  
Vol 11 (19) ◽  
pp. 9291
Author(s):  
Hafiz Muhammad Adil ◽  
Rizwan Jouhar ◽  
Muhammad Adeel Ahmed ◽  
Sakeenabi Basha ◽  
Naseer Ahmed ◽  
...  

Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), potassium nitrate, and sodium monofluorophosphate are desensitizing agents that help in reducing teeth sensitivity. However, indecisive evidence exists regarding their efficacy. Therefore, this study was conducted to compare the desensitizing efficacy of casein phosphopeptide-amorphous calcium phosphate and potassium nitrate with sodium monofluorophosphate agents after in-office vital bleaching. A randomized controlled trial was conducted on 2011 patients. The patients were randomly and equally divided into the CPP-ACP group (group 1), potassium nitrate with sodium monofluorophosphate group (group 2), and placebo gel (group 3). The upper and lower anterior teeth including the first premolar were isolated with a rubber dam, then the bleaching agents were applied on the labial surface of all the teeth, followed by light activation for 15 min. The procedure was repeated 3 times with an interval of 5 min in-between. After carrying out the bleaching procedure, patients were given a desensitizing gel or placebo gel in unmarked syringes with an instruction to apply it every 12 h for up to 3 days. The intensity of pain was recorded using a discomfort interval scale (DIS). A decrease in pain was observed 24 h after the application of the desensitizing gel in groups 1 and 2. However, in group 3, the pain persisted, with 46 (69.69%) patients having moderate pain and 14 (21.21%) developing severe pain over time. A significant difference in discomfort level with time was noted in group 1 (p = 0.015) and group 2 (p = 0.036). However, no significant difference was found in group 3 (p = 0.085). It was concluded that both desensitizing agents performed exceptionally well in reducing teeth sensitivity.


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