scholarly journals Polymorph Selection of ROY by Flow-Driven Crystallization

Crystals ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 351 ◽  
Author(s):  
Ziemecka ◽  
Gokalp ◽  
Stroobants ◽  
Brau ◽  
Maes ◽  
...  

The selection of polymorphs of the organic compound 5-methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile, ROY, is studied experimentally in the confined space between two horizontal glass plates when an acetone solution of ROY of variable concentration is injected at a variable flow rate into water. Depending on the local concentration within the radial flow, a polymorph selection is observed such that red prisms are favored close to the injection center while yellow needles are the preferred polymorph close to the edge of the injected ROY domain. At larger flow rates, a buoyancy-driven instability induces stripes at the outer edge of the displacement pattern, in which specific polymorphs are seen to crystallize. Our results evidence the possibility of a selection of ROY polymorph structures in out-of-equilibrium flow conditions.

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Tobias Blanke ◽  
Markus Hagenkamp ◽  
Bernd Döring ◽  
Joachim Göttsche ◽  
Vitali Reger ◽  
...  

AbstractPrevious studies optimized the dimensions of coaxial heat exchangers using constant mass flow rates as a boundary condition. They show a thermal optimal circular ring width of nearly zero. Hydraulically optimal is an inner to outer pipe radius ratio of 0.65 for turbulent and 0.68 for laminar flow types. In contrast, in this study, flow conditions in the circular ring are kept constant (a set of fixed Reynolds numbers) during optimization. This approach ensures fixed flow conditions and prevents inappropriately high or low mass flow rates. The optimization is carried out for three objectives: Maximum energy gain, minimum hydraulic effort and eventually optimum net-exergy balance. The optimization changes the inner pipe radius and mass flow rate but not the Reynolds number of the circular ring. The thermal calculations base on Hellström’s borehole resistance and the hydraulic optimization on individually calculated linear loss of head coefficients. Increasing the inner pipe radius results in decreased hydraulic losses in the inner pipe but increased losses in the circular ring. The net-exergy difference is a key performance indicator and combines thermal and hydraulic calculations. It is the difference between thermal exergy flux and hydraulic effort. The Reynolds number in the circular ring is instead of the mass flow rate constant during all optimizations. The result from a thermal perspective is an optimal width of the circular ring of nearly zero. The hydraulically optimal inner pipe radius is 54% of the outer pipe radius for laminar flow and 60% for turbulent flow scenarios. Net-exergetic optimization shows a predominant influence of hydraulic losses, especially for small temperature gains. The exact result depends on the earth’s thermal properties and the flow type. Conclusively, coaxial geothermal probes’ design should focus on the hydraulic optimum and take the thermal optimum as a secondary criterion due to the dominating hydraulics.


2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Jia Wang ◽  
Fabian Nitschke ◽  
Maziar Gholami Korzani ◽  
Thomas Kohl

Abstract Temperature logs have important applications in the geothermal industry such as the estimation of the static formation temperature (SFT) and the characterization of fluid loss from a borehole. However, the temperature distribution of the wellbore relies on various factors such as wellbore flow conditions, fluid losses, well layout, heat transfer mechanics within the fluid as well as between the wellbore and the surrounding rock formation, etc. In this context, the numerical approach presented in this paper is applied to investigate the influencing parameters/uncertainties in the interpretation of borehole logging data. To this end, synthetic temperature logs representing different well operation conditions were numerically generated using our newly developed wellbore simulator. Our models account for several complex operation scenarios resulting from the requirements of high-enthalpy wells where different flow conditions, such as mud injection with- and without fluid loss and shut-in, occur in the drill string and the annulus. The simulation results reveal that free convective heat transfer plays an important role in the earlier evolution of the shut-in-time temperature; high accuracy SFT estimation is only possible when long-term shut-in measurements are used. Two other simulation scenarios for a well under injection conditions show that applying simple temperature correction methods on the non-shut-in temperature data could lead to large errors for SFT estimation even at very low injection flow rates. Furthermore, the magnitude of the temperature gradient increase depends on the flow rate, the percentage of fluid loss and the lateral heat transfer between the fluid and the rock formation. As indicated by this study, under low fluid losses (< 30%) or relatively higher flow rates (> 20 L/s), the impact of flow rate and the lateral heat transfer on the temperature gradient increase can be ignored. These results provide insights on the key factors influencing the well temperature distribution, which are important for the choice of the drilling data to estimate SFT and the design of the inverse modeling scheme in future studies to determine an accurate SFT profile for the high-enthalpy geothermal environment.


2010 ◽  
Vol 132 (7) ◽  
Author(s):  
Yiemeng Hoi ◽  
Bruce A. Wasserman ◽  
Edward G. Lakatta ◽  
David A. Steinman

Recent work has illuminated differences in carotid artery blood flow rate dynamics of older versus young adults. To what degree flow waveform shape, and indeed the use of measured versus assumed flow rates, affects the simulated hemodynamics of older adult carotid bifurcations has not been elucidated. Image-based computational fluid dynamics models of N=9 normal, older adult carotid bifurcations were reconstructed from magnetic resonance angiography. Subject-specific hemodynamics were computed by imposing each individual’s inlet and outlet flow rates measured by cine phase-contrast magnetic resonance imaging or by imposing characteristic young and older adult flow waveform shapes adjusted to cycle-averaged flow rates measured or allometrically scaled to the inlet and outlet areas. Despite appreciable differences in the measured versus assumed flow conditions, the locations and extents of low wall shear stress and elevated relative residence time were broadly consistent; however, the extent of elevated oscillatory shear index was substantially underestimated, more by the use of assumed cycle-averaged flow rates than the assumed flow waveform shape. For studies of individual vessels, use of a characteristic flow waveform shape is likely sufficient, with some benefit offered by scaling to measured cycle-averaged flow rates. For larger-scale studies of many vessels, ranking of cases according to presumed hemodynamic or geometric risk is robust to the assumed flow conditions.


1980 ◽  
Vol 47 (4) ◽  
pp. 736-740 ◽  
Author(s):  
D. Durban

The process of the tube drawing between two rough conical walls is analyzed within the framework of continuum plasticity. Material behavior is modeled as rigid/linear-hardening along with the von-Mises flow rule. Assuming a radial flow pattern and steady state flow conditions it becomes possible to obtain an exact solution for the stresses and velocity. Useful relations are derived for practical cases where the nonuniformity induced by wall friction is small. A few restrictions on the validity of the results are discussed.


Author(s):  
Ganesh Marotrao KAKANDIKAR ◽  
Vilas M. NANDEDKAR

Forming is a compression-tension process involving wide spectrum of operations and flow conditions. The result of the process depends on the large number of parameters and their interdependence. The selection of various parameters is still based on trial and error methods. In this paper the authors presents a new approach to optimize the geometry parameters of circular components, process parameters such as blank holder pressure and coefficient of friction etc. The optimization problem has been formulated with the objective of optimizing the maximum forming load required in Forming. Genetic algorithm is used for the optimization purpose to minimize the drawing load and to optimize the process parameters. A finite element analysis simulation software Fast Form Advanced is used for the validations of the results after optimization.


2018 ◽  
pp. 221-231
Author(s):  
John R. B. Lighton

This chapter discusses several often-neglected areas of respirometry infrastructure. These include the correct selection of scrubber chemicals for removing water vapor and/or carbon dioxide from air streams, without undesirable interactions; chemical-free scrubbing techniques such as selective membranes, thermal condensing systems, and mathematical correction for water vapor dilution; selecting tubing for metabolic measurement; evaluating the different tubing chemistries in light of the intended application; selecting appropriate tubing diameters for the flow rates that will be used; selecting tubing connectors; maintaining connector gender conventions to minimize plumbing confusion; and other related topics.


Fluids ◽  
2018 ◽  
Vol 3 (4) ◽  
pp. 73 ◽  
Author(s):  
Galih Bangga

The present studies deliver the computational investigations of a 10 MW turbine with a diameter of 205.8 m developed within the framework of the AVATAR (Advanced Aerodynamic Tools for Large Rotors) project. The simulations were carried out using two methods with different fidelity levels, namely the computational fluid dynamics (CFD) and blade element and momentum (BEM) approaches. For this purpose, a new BEM code namely B-GO was developed employing several correction terms and three different polar and spatial interpolation options. Several flow conditions were considered in the simulations, ranging from the design condition to the off-design condition where massive flow separation takes place, challenging the validity of the BEM approach. An excellent agreement is obtained between the BEM computations and the 3D CFD results for all blade regions, even when massive flow separation occurs on the blade inboard area. The results demonstrate that the selection of the polar data can influence the accuracy of the BEM results significantly, where the 3D polar datasets extracted from the CFD simulations are considered the best. The BEM prediction depends on the interpolation order and the blade segment discretization.


Micromachines ◽  
2019 ◽  
Vol 10 (12) ◽  
pp. 812 ◽  
Author(s):  
Wen Zeng ◽  
Dong Xiang ◽  
Hai Fu

In a flow-focusing microdroplet generator, by changing the flow rates of the two immiscible fluids, production speed can be increased from tens to thousands of droplets per second. However, because of the nonlinearity of the flow-focusing microdroplet generator, the production speed of droplets is difficult to quantitatively study for the typical flow-focusing geometry. In this paper, we demonstrate an efficient method that can precisely predict the droplet production speed for a wide range of fluid flow rates. While monodisperse droplets are formed in the flow-focusing microchannel, droplet spacing as a function of time was measured experimentally. We discovered that droplet spacing changes periodically with time during each process of droplet generation. By comparing the frequency of droplet spacing fluctuations with the droplet production speed, precise predictions of droplet production speed can be obtained for different flow conditions in the flow-focusing microdroplet generator.


Sensors ◽  
2019 ◽  
Vol 19 (20) ◽  
pp. 4560 ◽  
Author(s):  
Park ◽  
Kim ◽  
Kim ◽  
Pyun ◽  
Sung

A portable urea sensor for use in fast flow conditions was fabricated using porous polytetrafluoroethylene (PTFE) membranes coated with amine-functionalized parylene, parylene-A, by vapor deposition. The urea-hydrolyzing enzyme urease was immobilized on the parylene-A-coated PTFE membranes using glutaraldehyde. The urease-immobilized membranes were assembled in a polydimethylsiloxane (PDMS) fluidic chamber, and a screen-printed carbon three-electrode system was used for electrochemical measurements. The success of urease immobilization was confirmed using scanning electron microscopy, and fourier-transform infrared spectroscopy. The optimum concentration of urease for immobilization on the parylene-A-coated PTFE membranes was determined to be 48 mg/mL, and the optimum number of membranes in the PDMS chamber was found to be eight. Using these optimized conditions, we fabricated the urea biosensor and monitored urea samples under various flow rates ranging from 0.5 to 10 mL/min in the flow condition using chronoamperometry. To test the applicability of the sensor for physiological samples, we used it for monitoring urea concentration in the waste peritoneal dialysate of a patient with chronic renal failure, at a flow rate of 0.5 mL/min. This developed urea biosensor is considered applicable for (portable) applications, such as artificial kidney systems and portable dialysis systems.


2015 ◽  
Vol 71 (10) ◽  
pp. 1485-1491 ◽  
Author(s):  
Mingfu Guan ◽  
Nora Sillanpää ◽  
Harri Koivusalo

This study quantifies the effects of common stormwater management techniques on urban runoff generation. Simulated flow rates for different low impact development (LID) scenarios were compared with observed flow rates during different urban construction phases in a catchment (12.3 ha) that was developed from natural forest to a residential area over a monitoring period of 5 years. The Storm Water Management Model (SWMM) was calibrated and validated against the observed flow rates in the fully developed catchment conditions, and it was then applied to parameterize the LID measures and produce scenarios of their hydrological impacts. The results from the LID scenarios were compared with the observed flow rates in the pre-development and the partially developed catchment conditions. The results show that LID controls reduce urban runoff towards the flow conditions in the partially developed catchment, but the reduction effect diminishes during large rainfall events. The hydrographs with LID are still clearly different from the observed pre-development levels. Although the full restoration of pre-development flow conditions was not feasible, a combination of several measures controlling both volumes and retention times of storm runoff appeared to be effective for managing the stormwater runoff and mitigating the negative impacts of urban development.


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