scholarly journals Special Issue “Recent Developments in Annexin Biology”

Cells ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 2477
Author(s):  
Ursula Rescher ◽  
Volker Gerke ◽  
Lina Hsiu Kim Lim ◽  
Jyoti K. Jaiswal
Keyword(s):  
Biomedical Research ◽  
Basic Science ◽  
Global Network ◽  
Cellular Organization ◽  
Special Issue ◽  
Recent Developments ◽  
Health And Disease ◽  
Over 40 Years ◽  
Initial Research

Discovered over 40 years ago, the annexin proteins were found to be a structurally conserved subgroup of Ca2+-binding proteins. While the initial research on annexins focused on their signature feature of Ca2+-dependent binding to membranes, over the years the biennial Annexin conference series has highlighted additional diversity in the functions attributed to the annexin family of proteins. The roles of these proteins now extend from basic science to biomedical research, and are being translated into the clinic. The research on annexins involves a global network of researchers, and the 10th biennial Annexin conference brought together over 80 researchers from ten European countries, USA, Brazil, Singapore, Japan and Australia for 3 days in September 2019. In this conference, the discussions focused on two distinct themes—the role of annexins in cellular organization and in health and disease. The articles published in this Special Issue cover these two main themes discussed at this conference, offering a glimpse into some of the notable findings in the field of annexin biology.

scholarly journals Inflammation and Atherosclerosis

Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1197
Author(s):  
Klaus Ley
Keyword(s):  
Clinical Trials ◽  
Animal Models ◽  
Basic Science ◽  
Translational Science ◽  
Special Issue

This 11-chapter Special Issue of Cells spans the gamut from basic science in mechanistic animal models to translational science to outcomes of clinical trials, all focused on the role of inflammation in atherosclerosis [...]

The Salivary miRNome: A Promising Biomarker of Disease

MicroRNA ◽  
2021 ◽  
Vol 10 ◽  
Author(s):  
Sara Tomei ◽  
Harshitha Shobha Manjunath ◽  
Selvasankar Murugesan ◽  
Souhaila Al Khodor
Keyword(s):  
Current Knowledge ◽  
Transcriptional Level ◽  
Biological Processes ◽  
Circulating Mirnas ◽  
Disease Pathogenesis ◽  
Technical Aspects ◽  
Recent Developments ◽  
Health And Disease ◽  
Non Coding Rnas

: MicroRNAs (miRNAs) are non-coding RNAs ranging from 18-24 nucleotides also known to regulate the human genome mainly at the post-transcriptional level. MiRNAs were shown to play an important role in most biological processes such as apoptosis and in the pathogenesis of many diseases such as cardiovascular diseases and cancer. Recent developments of advanced molecular high-throughput technologies have enhanced our knowledge of miRNAs. MiRNAs can now be discovered, interrogated, and quantified in various body fluids, and hence can serve as diagnostic and therapeutic markers for many diseases. While most studies use blood as a sample source to measure circulating miRNAs as possible biomarkers for disease pathogenesis, fewer studies have assessed the role of salivary miRNAs in health and disease. This review aims at providing an overview of the current knowledge of the salivary miRNome, addressing the technical aspects of saliva sampling and highlighting the applicability of miRNA screening to clinical practice.

scholarly journals Local Antimicrobial Treatment in Orthopaedic Surgery

2017 ◽  
Vol 2 (1) ◽  
pp. 1-2
Author(s):  
Antonia F. Chen ◽  
Heinz Winkler
Keyword(s):  
Basic Science ◽  
Orthopaedic Surgery ◽  
Clinical Evidence ◽  
Joint Infection ◽  
Antimicrobial Treatment ◽  
Special Issue ◽  
Orthopaedic Surgeons ◽  
Bone And Joint Infection

Abstract. The purpose of this special issue of Journal of Bone and Joint Infection is to provide orthopaedic surgeons with basic science explanations as to how these local antimicrobials work, clinical evidence that supports these local treatments, and the role of these local treatments against biofilm.

scholarly journals Bulk Collection

2017 ◽  
Keyword(s):  
Large Scale ◽  
Phone Call ◽  
Personal Privacy ◽  
Us Government ◽  
Recent Developments ◽  
Access To Data ◽  
The Uk ◽  
Systematic Collection ◽  
Initial Research

In June 2013, Edward Snowden revealed a secret US government program that collected records on every phone call made in the country. Further disclosures followed, detailing mass surveillance by the UK as well. Journalists and policymakers soon began discussing large-scale programs in other countries. Over two years before the Snowden leaks began, Cate and Dempsey had started researching systematic collection. Leading an initiative sponsored by The Privacy Projects, they commissioned a series of country reports, asking national experts to uncover what they could about government demands that telecommunications providers and other private-sector companies disclose information about their customers in bulk. Their initial research found disturbing indications of systematic access in countries around the world. These programs, often undertaken in the name of national security, were cloaked in secrecy and largely immune from oversight, posing serious threats to personal privacy. After the Snowden leaks, the project morphed into something more ambitious: an effort to explore what should be the rules for government access to data and how companies should respond to those demands within the framework of corporate responsibility. This volume concludes the nearly six-year project. It assembles 12 country reports, updated to reflect recent developments. One chapter presents both descriptive and normative frameworks for analyzing national surveillance laws. Others examine international law, human rights law, and oversight mechanisms. Still others explore the concept of accountability and the role of encryption in shaping the surveillance debate. In their conclusion, Cate and Dempsey offer recommendations for both government and industry.

The role of sex in cardiac function and diseaseThis paper is one of a selection of papers published in this Special Issue, entitled Young Investigator's Forum.

2006 ◽  
Vol 84 (1) ◽  
pp. 93-109 ◽  
Author(s):  
Michael P. Czubryt ◽  
Leon Espira ◽  
Lise Lamoureux ◽  
Bernard Abrenica
Keyword(s):  
Disease Susceptibility ◽  
Heart Function ◽  
Cardiac Diseases ◽  
Special Issue ◽  
Isolated Cardiomyocytes ◽  
The Past ◽  
Health And Disease ◽  
Shed Light ◽  
Selection Of

In the past decade, increasing attention has been paid to the importance of sex in the etiology of cardiac dysfunction. While focus has been primarily on how sex modulates atherogenesis, it is becoming clear that sex is both a predictor of outcome and an independent risk factor for a number of other cardiac diseases. Animal models and human studies have begun to shed light on the mechanisms by which sex influences the function of cardiomyocytes in health and disease. This review will survey the current literature on cardiac diseases that are influenced by sex and discuss the intracellular mechanisms by which steroid sex hormones affect heart function. A theory on how sex may regulate myocardial energy metabolism to affect disease susceptibility and progression will be presented, as well as a discussion of how sex may influence outcomes of experiments on isolated cardiomyocytes by epigenetic marking.

scholarly journals Editorial of Special Issue “Magnesium in Human Health and Disease”

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2490
Author(s):  
Sara Castiglioni
Keyword(s):  
Human Health ◽  
Special Issue ◽  
Health And Disease

The fundamental role of magnesium in human health is extensively discussed in the review by Fiorentini and colleagues [...]

scholarly journals Editorial for the Special Issue: The Role of the Virome in Health and Disease

2021 ◽  
Vol 10 (1) ◽  
pp. 20
Author(s):  
Felix Broecker
Keyword(s):  
Special Issue ◽  
Health And Disease ◽  
Biological Entities

Viruses are the most abundant biological entities on Earth, with an estimated total of 1031 virions [...]

scholarly journals Editorial of Special Issue “Rare Kidney Diseases: New Translational Research Approach to Improve Diagnosis and Therapy”

2020 ◽  
Vol 21 (12) ◽  
pp. 4244
Author(s):  
Gianluigi Zaza ◽  
Giovanni Gambaro
Keyword(s):  
Translational Research ◽  
Biomedical Research ◽  
Kidney Diseases ◽  
Research Approach ◽  
Special Issue ◽  
Diagnosis And Therapy

In this Special Issue entitled “Rare Kidney Diseases: New Translational Research Approach to Improve Diagnosis and Therapy”, of the International Journal of Molecular Sciences, that includes original articles and reviews, authors have underlined the role of biomedical research in providing new insights into the pathologies of complex kidney diseases [...]

scholarly journals Arctic entomology in the 21st century

2013 ◽  
Vol 145 (2) ◽  
pp. 125-130 ◽  
Author(s):  
Toke T. Høye ◽  
Derek S. Sikes
Keyword(s):  
21St Century ◽  
The Arctic ◽  
Model Organisms ◽  
Special Issue ◽  
Ideal Model ◽  
Research Activity ◽  
Abiotic Environment ◽  
Research Fields ◽  
Recent Developments

AbstractResearch interest in the Arctic is accelerating because of observed and anticipated dramatic climate change and its impacts on societies and ecosystems. Arthropods form a major part of the terrestrial species diversity in the Arctic, and are particularly sensitive to changes in the abiotic environment. Hence, increased research activity on Arctic arthropods would help towards conservation of Arctic biodiversity as well as in understanding the role of Arctic arthropods in ecosystem functioning. In this introduction to the special issue on Arctic entomology in the 21st century, we identify trophic interactions, biodiversity assessments, and taxonomic revisions as three important research fields in Arctic entomology. We also point to ways in which Arctic entomology could take advantage of recent developments in other research fields and we place the contributions to the special issue in a broader context. Arthropods form ideal model organisms in global change studies and there is a particular need for entomological studies from the dramatically changing Arctic. It is our hope that the papers within this special issue will be a valuable source of inspiration and may stimulate novel insights and achievements in Arctic entomology during the 21st century.

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