scholarly journals A Heterozygous ZMPSTE24 Mutation Associated with Severe Metabolic Syndrome, Ectopic Fat Accumulation, and Dilated Cardiomyopathy

Cells ◽  
2016 ◽  
Vol 5 (2) ◽  
pp. 21 ◽  
Author(s):  
Damien Galant ◽  
Bénédicte Gaborit ◽  
Camille Desgrouas ◽  
Ines Abdesselam ◽  
Monique Bernard ◽  
...  
2007 ◽  
Vol 9 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Neda Rasouli ◽  
Behzad Molavi ◽  
Steven C. Elbein ◽  
Philip A. Kern

2008 ◽  
Vol 116 (2) ◽  
pp. 113-123 ◽  
Author(s):  
Margaret J. Hill ◽  
David Metcalfe ◽  
Philip G. McTernan

Although specific pathogenic entities contributing to diabetic risk, such as central adiposity, ectopic fat accumulation, hyperlipidaemia and inflammation, are well-characterized, the response of cellular systems to such insults are less well understood. This short review highlights the effect of increasing fat mass on ectopic fat accumulation, the role of triacylglycerols (triglycerides) in Type 2 diabetes mellitus and cardiovascular disease pathogenesis, and selected current therapeutic strategies used to ameliorate these risk factors.


2021 ◽  
Author(s):  
Marina Leer ◽  
George Soultoukis ◽  
Francisco J. Garcia-Carrizo ◽  
Tim J. Schulz

Medicine ◽  
2020 ◽  
Vol 99 (37) ◽  
pp. e22202
Author(s):  
Masakazu Kobayashi ◽  
Sayaka Ogawa ◽  
Jun Tayama ◽  
Ikuko Sagara ◽  
Atsushi Takeoka ◽  
...  

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1430 ◽  
Author(s):  
Hitoshi Nishizawa ◽  
Iichiro Shimomura

The clinical importance of assessment of metabolic syndrome lies in the selection of individuals with multiple risk factors based on visceral fat accumulation, and helping them to reduce visceral fat. Behavioral modification by population approach is important, which adds support to the personal approach. The complexity of visceral fat accumulation requires multicomponent and multilevel intervention. Preparation of food and physical environments could be useful strategies for city planners. Furthermore, actions on various frameworks, including organizational, community, and policy levels, have been recently reported. There are universal public health screening programs and post-screening health educational systems in Japan, and diseases management programs in Germany. Understanding one’s own health status is important for motivation for lifestyle modification. The U.S. Preventive Services Task Force recommends that primary care practitioners screen all adults for obesity and offer behavioral interventions and intensive counseling. Established evidence-based guidelines for behavioral counseling are needed within the primary care setting.


Sign in / Sign up

Export Citation Format

Share Document