scholarly journals Vaccines against COVID-19: Priority to mRNA-Based Formulations

Cells ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2716
Author(s):  
Steve Pascolo

As of September 2021, twenty-one anti-COVID-19 vaccines have been approved in the world. Their utilization will expedite an end to the current pandemic. Besides the usual vaccine formats that include inactivated viruses (eight approved vaccines) and protein-based vaccines (four approved vaccines), three new formats have been validated: recombinant adenovirus (six approved vaccines), DNA (one approved vaccine), and messenger RNA (mRNA, two approved vaccines). The latter was the fastest (authorized in 2020 in the EU, the USA, and Switzerland). Most Western countries have reserved or use the protein vaccines, the adenovirus vaccines, and mRNA vaccines. I describe here the different vaccine formats in the context of COVID-19, detail the three formats that are chiefly reserved or used in Europe, Canada, and the USA, and discuss why the mRNA vaccines appear to be the superior format.

Author(s):  
K. Voronov

Despite the crisis, the economy of the European Union remains to be the largest in the world. The economic mechanism of the EU is rather differentiated. It has a great historical experience and possesses sufficient evolutionary robustness. Currently, the former relationships between the EU and the USA undergo substantial changes and new forms emerge. For both of them the greatest challenge is presented by China which in recent decades shows the solid rates of GDP growth. Supposedly, Chines economy will become the world largest on in the new future. Under such conditions the Old World has to conduct a persistent search for new sources of its successful macroeconomic growth.


BMJ Open ◽  
2017 ◽  
Vol 7 (11) ◽  
pp. e018705 ◽  
Author(s):  
Gonzalo Casino ◽  
Roser Rius ◽  
Erik Cobo

ObjectivesTo analyse the total number of newspaper articles citing the four leading general medical journals and to describe national citation patterns.DesignQuantitative content analysis.Setting/sampleFull text of 22 general newspapers in 14 countries over the period 2008–2015, collected from LexisNexis. The 14 countries have been categorised into four regions: the USA, the UK, Western World (European countries other than the UK, and Australia, New Zealand and Canada) and Rest of the World (other countries).Main outcome measurePress citations of four medical journals (two American:NEJMandJAMA; and two British:The LancetandThe BMJ) in 22 newspapers.ResultsBritish and American newspapers cited some of the four analysed medical journals about three times a week in 2008–2015 (weekly mean 3.2 and 2.7 citations, respectively); the newspapers from other Western countries did so about once a week (weekly mean 1.1), and those from the Rest of the World cited them about once a month (monthly mean 1.1). The New York Times cited above all other newspapers (weekly mean 4.7). The analysis showed the existence of three national citation patterns in the daily press: American newspapers cited mostly American journals (70.0% of citations), British newspapers cited mostly British journals (86.5%) and the rest of the analysed press cited more British journals than American ones.The Lancetwas the most cited journal in the press of almost all Western countries outside the USA and the UK. Multivariate correspondence analysis confirmed the national patterns and showed that over 85% of the citation data variability is retained in just one single new variable: the national dimension.ConclusionBritish and American newspapers are the ones that cite the four analysed medical journals more often, showing a domestic preference for their respective national journals; non-British and non-American newspapers show a common international citation pattern.


2020 ◽  
Vol 72 ◽  
pp. 107-109
Author(s):  
Purvish M. Parikh ◽  
Ajay Bapna ◽  
M. Vamshi Krishna ◽  
Prashant Mehta ◽  
Shyam Aggarwal ◽  
...  

In terms of the absolute number of COVID-19 positive cases, India is among the top four countries in the world. There is a lot of unwarranted criticism about the alleged inadequacy of COVID-19 testing in India. The facts available from international and publicly available online non-government source covering the entire world show otherwise. While India is fourth in terms of an absolute number of cases, its rank is 132nd in terms of cases per million population and 107th for deaths per million population. These are indications that India is doing much better in the battle against COVID-19 than it is getting credit for. The correct benchmark for the adequacy of testing is the percentage of COVID-19 positive results as compared to the total number of tests performed. India ranks 5th (out of 215) in this respect – being better than some western countries such as the USA, Spain, and France. Thus, the Indian strategy for COVID-19 testing is better and more appropriate than the majority of other countries with the large absolute number of positive cases.


2021 ◽  
pp. 35-50
Author(s):  
André Sapir

After two prosperous decades, the European Union suffered a serious setback in the late 1970s and early 1980s, with sluggish growth and weak competitiveness in high-tech sectors compared to the USA and Japan. The creation of the single European market in 1993 was a major boost to growth and competitiveness in Europe. Yet, today, even abstracting from the coronavirus crisis, the European Union again faces some economic troubles. Growth has been subdued for a while and the EU is suffering yet again from weak competitiveness in high-tech sectors compared to the USA and to China, which has replaced Japan as the main Asian powerhouse. At the same time, however, the geopolitical situation has changed dramatically. In the earlier days, the world was divided between East and West, and all three main economic powers, the EU, Japan, and the USA, were in the same political camp. Their rivalry was therefore purely economic. Today, there are political dividing lines between the three main economic powers. The EU’s competitiveness problem vis-à-vis China and the USA in some key technologies is therefore not just economic but also geopolitical. Yet, the European Union remains largely an economic entity, though it has started to think and even to act geopolitically. The obvious question is whether Europe will be able to repeat its achievement of nearly 30 years ago and come up with a new design that will boost its growth and competitiveness in this new geopolitical era, or whether this quest will prove elusory.


2019 ◽  
Vol 22 (2) ◽  
pp. 388-399 ◽  
Author(s):  
Stefan Cassella

Purpose The purpose of this paper is to review recent examples of sophisticated money laundering operations involving financial institutions in Eurasia, including Russia and Moldova, and the resulting flow of licit and illicit capital from that part of the world to the UK, the USA, and other Western countries. Design/methodology/approach Relying on materials from publicly available sources, the study uses several case studies to illustrate various money laundering methods with a view toward identifying common elements and aspects of the schemes that might be considered new or innovative. Findings In particular, the study examines the roles that lax anti-money laundering compliance by financial institutions and the use of shell corporations designed to conceal the beneficial ownership of the companies and their assets have played in virtually all of the money laundering schemes. Originality/value The paper discusses the risks that these emerging money laundering methods pose to Western countries and their financial institutions and the approaches that governments might take to minimize those risks and raise the barriers for the laundering of illicit funds within their jurisdictions.


2008 ◽  
Vol 8 (1) ◽  
pp. 33-52 ◽  
Author(s):  
Sarah Lieberman ◽  
Tim Gray

The World Trade Organization (WTO) recently ruled on the case brought by the US, Canada and Argentina against the moratorium imposed by the European Union (EU) on imports of genetically-modified (GM) food and crops. Although the WTO's ruling has been greeted by the complainant countries as a victory, it found in their favor on only one narrow technical procedural issue, and it rejected more substantive challenges to the EU moratorium. In this article, we analyze the WTO report and explain the issues at stake, focusing particularly on the question of why the USA chose the WTO as the forum for its challenge to the EU moratorium, and whether it was wise to do so. Has the USA achieved its aims through the trade-specific WTO, or should it have taken its challenge to the more hostile, but environment-specific forum of the Cartagena Protocol on Biosafety? Alternatively, should the USA have refrained from mounting an official international challenge at all?


Author(s):  
Stanisław Stańko ◽  
Aneta Mikuła

The study presents changes in the world pork market and in Poland in the years 2000-2016. Changes in the main producers and consumers, as well as exporters and importers were presented. The major global producers of pork are China, the EU, USA, Brazil, Russia and Vietnam, which in 2016 produced 88.2% of total world production. In the world’s major pork producers (except China), consumption growth was slower than production growth, which increased their export capacity. In the years 2000-2016, the growth rate of international trade was higher than production, what led to an increase in the share of exports in production. Global pork exports is characterized by a large and growing concentration rate. In 2016, 37.6% of exports came from the EU, 28.5% from the USA, 15.9% from Canada and 10% from Brazil (total 92% of exports). World pork imports were characterized by a much greater dispersion than exports. Pork prices have shown an upward trend. In Poland there was a downward trend in pork production and growth in consumption, which caused that since 2008 Poland is a net importer of pork. Poland will remain a net importer of pork in the medium term.


2006 ◽  
Vol 78 (8) ◽  
pp. 1477-1491 ◽  
Author(s):  
Alan Mortensen

Food colorants may be classified into synthetic, nature-identical, inorganic, and natural colorants. Natural colorants for food are made from renewable sources. Most often, the colorants are extracted from plant material, but other sources such as insects, algae, cyanobacteria, and fungi are used as well. Natural colorants are usually extracted and concentrated using either water or lower alcohols for water-soluble pigments and organic solvents for lipophilic pigments. Legislation restricts which colorants are allowed, what sources may be used for that particular colorant, what solvents may be used to extract it, and the purity of the pigment. Colorants are formulated to make them more suitable for a variety of foods and drinks (e.g., lipophilic pigments for use in beverages) and to increase their stability. The natural colorants allowed in the EU and the USA are presented. Many of these colorants are also allowed in most parts of the world. A few colorants that are not allowed in the EU and the USA, but are important food colorants in other parts of the world, are also presented.


2018 ◽  
Vol 18(33) (4) ◽  
pp. 437-450
Author(s):  
Stanisław Stańko ◽  
Aneta Mikuła

Changes in production and trends in shortages / market surpluses of butter and cheese in the world and in Poland in 2001-2017 were presented. Market surplus of butter increased in New Zealand, EU and Belarus, and decreased in Australia and Ukraine. Shortages grew in China, Mexico, Iran and Turkey, and decreased in Russia and Canada. Relatively balanced production and consumption occurred in India, Pakistan, the USA and Brazil. On the cheese market, surplus grew in: EU, USA, New Zealand, Argentina and Belarus, and decreased in Australia and Ukraine. The shortages grew in: Russia, Brazil, Mexico. In Poland, there were surpluses in butter and cheese production, which resulted in growing exports, directed mainly to EU countries. Prices of butter and cheese in EU countries and on the world market were characterized by convergence. At the beginning of the analyzed period, butter prices in the EU were 134% higher than on the world market, and cheese prices were higher by 92.6%, and in 2017 these differences were respectively 6% and 0.6%.


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