scholarly journals Electrochemiluminescence Biosensors Using Screen-Printed Electrodes

Biosensors ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 118
Author(s):  
Emiliano Martínez-Periñán ◽  
Cristina Gutiérrez-Sánchez ◽  
Tania García-Mendiola ◽  
Encarnación Lorenzo
Keyword(s):  
Dna Analysis ◽  
Dynamic Range ◽  
Chemical Properties ◽  
High Sensitivity ◽  
Portable Devices ◽  
Research Fields ◽  
Sensing Applications ◽  
Screen Printed Electrodes ◽  
Wide Range ◽  
Screen Printed

Electrogenerated chemiluminescence (also called electrochemiluminescence (ECL)) has become a great focus of attention in different fields of analysis, mainly as a consequence of the potential remarkably high sensitivity and wide dynamic range. In the particular case of sensing applications, ECL biosensor unites the benefits of the high selectivity of biological recognition elements and the high sensitivity of ECL analysis methods. Hence, it is a powerful analytical device for sensitive detection of different analytes of interest in medical prognosis and diagnosis, food control and environment. These wide range of applications are increased by the introduction of screen-printed electrodes (SPEs). Disposable SPE-based biosensors cover the need to perform in-situ measurements with portable devices quickly and accurately. In this review, we sum up the latest biosensing applications and current progress on ECL bioanalysis combined with disposable SPEs in the field of bio affinity ECL sensors including immunosensors, DNA analysis and catalytic ECL sensors. Furthermore, the integration of nanomaterials with particular physical and chemical properties in the ECL biosensing systems has improved tremendously their sensitivity and overall performance, being one of the most appropriates research fields for the development of highly sensitive ECL biosensor devices.

scholarly journals Airborne fine-resolution UHF radar: an approach to the study of englacial reflections, firn compaction and ice attenuation rates

2015 ◽  
Vol 61 (225) ◽  
pp. 89-100 ◽  
Author(s):  
Cameron Lewis ◽  
Sivaprasad Gogineni ◽  
Fernando Rodriguez-Morales ◽  
Ben Panzer ◽  
Theresa Stumpf ◽  
...  
Keyword(s):  
Dynamic Range ◽  
High Sensitivity ◽  
Ultra Wideband ◽  
West Antarctica ◽  
Ice Shelves ◽  
Ross Ice Shelf ◽  
Transmission Coefficients ◽  
Ice Surface ◽  
Wide Range ◽  
Fine Resolution

AbstractWe have built and operated an ultra-wideband UHF pulsed-chirp radar for measuring firn stratigraphy from airborne platforms over the ice sheets of Greenland and West Antarctica. Our analysis found a wide range of capabilities, including imaging of post firn–ice transition horizons and sounding of shallow glaciers and ice shelves. Imaging of horizons to depths exceeding 600 m was possible in the colder interior regions of the ice sheet, where scattering from the ice surface and inclusions was minimal. The radar’s high sensitivity and large dynamic range point to loss tangent variations as the dominant mechanism for these englacial reflective horizons. The radar is capable of mapping interfaces with reflection coefficients as low as −80 dB near the firn–ice transition and as low as −64 dB at depths of 600 m. We found that firn horizon reflectivity strongly mirrored density variance, a result of the near-unity interfacial transmission coefficients. Zones with differing compaction mechanisms were also apparent in the data. We were able to sound many ice shelves and areas of shallow ice. We estimated ice attenuation rates for a few locations, and our attenuation estimates for the Ross Ice Shelf, West Antarctica, appear to agree well with earlier reported results.

scholarly journals A dual electro-optical biosensor based on Chlamydomonas reinhardtii immobilised on paper-based nanomodified screen-printed electrodes for herbicide monitoring

2021 ◽  
Author(s):  
Amina Antonacci ◽  
Raouia Attaallah ◽  
Fabiana Arduini ◽  
Aziz Amine ◽  
Maria Teresa Giardi ◽  
...  
Keyword(s):  
Chlamydomonas Reinhardtii ◽  
High Sensitivity ◽  
Optical Biosensor ◽  
Whole Cells ◽  
Screen Printed Electrodes ◽  
And Storage ◽  
High Repeatability ◽  
High Sensitivity Detection ◽  
Screen Printed

Abstract The indiscriminate use of herbicides in agriculture contributes to soil and water pollution, with important endangering consequences on the ecosystems. Among the available analytical systems, algal biosensors have demonstrated to be valid tools thanks to their high sensitivity, cost-effectiveness, and eco-design. Herein, we report the development of a dual electro-optical biosensor for herbicide monitoring, based on Chlamydomonas reinhardtii whole cells immobilised on paper-based screen-printed electrodes modified with carbon black nanomaterials. To this aim, a systematic study was performed for the selection and characterisation of a collection among 28 different genetic variants of the alga with difference response behaviour towards diverse herbicide classes. Thus, CC125 strain was exploited as case study for the study of the analytical parameters. The biosensor was tested in standard solutions and real samples, providing high sensitivity (detection limit in the pico/nanomolar), high repeatability (RSD of 5% with n = 100), long lasting working (10 h) and storage stability (3 weeks), any interference in the presence of heavy metals and insecticides, and low matrix effect in drinking water and moderate effect in surface one.

Potentiometric Taste Sensing Using Reduced Graphene Oxide Screen Printed Electrodes

2020 ◽  
Vol 18 (12) ◽  
pp. 881-888
Author(s):  
Anil B. Patil ◽  
Umesh. J. Tupe ◽  
Vikas V. Deshmane ◽  
Arun V. Patil
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Principal Component ◽  
Experimental Results ◽  
Statistical Tool ◽  
Sensing Applications ◽  
Screen Printed Electrodes ◽  
Reduced Graphene ◽  
Pharmaceutical Industries ◽  
Screen Printed

This paper reports the development of simple and economical reduced graphene oxide (rGO) based screen-printed electrodes (SPE) for five basic taste sensing applications. Twenty different test solutions for the five tastes of salty, sour, sweet, umami, and bitter at 1 ppm, 10 ppm, 100 ppm, 1000 ppm concentration levels were tested with the fabricated SPEs. From experimental results, electrical signals generated between the electrode and test solution interface were measured using the potentiometric method. Satisfactory potentiometric responses of SPEs to different ppm concentrations for each sample were used to analyze the sample data. Histogram using the statistical tool was used to analyze the changes in the conductivity response. A multivariate Principal Component Analysis (PCA) statistical tool correlated using loading plots between variables and factors of all the five basic tastes. The plot showed the interrelation between variables and test samples. The obtained experimental results from these rGO based SPEs make them suitable for their use in taste sensing applications such as for any taste disorder disability, food-producing industry, pharmaceutical industries, etc.

scholarly journals Programmable Paper-Based Microfluidic Devices for Biomarker Detections

Micromachines ◽  
2019 ◽  
Vol 10 (8) ◽  
pp. 516 ◽  
Author(s):  
Veasna Soum ◽  
Sooyong Park ◽  
Albertus Ivan Brilian ◽  
Oh-Sun Kwon ◽  
Kwanwoo Shin
Keyword(s):  
Point Of Care ◽  
High Sensitivity ◽  
Microfluidic Devices ◽  
Portable Devices ◽  
Biomarker Detection ◽  
Fluid Delivery ◽  
Wide Range ◽  
Paper Based Microfluidics ◽  
Digital Microfluidic ◽  
Detection Of Biomarkers

Recent advanced paper-based microfluidic devices provide an alternative technology for the detection of biomarkers by using affordable and portable devices for point-of-care testing (POCT). Programmable paper-based microfluidic devices enable a wide range of biomarker detection with high sensitivity and automation for single- and multi-step assays because they provide better control for manipulating fluid samples. In this review, we examine the advances in programmable microfluidics, i.e., paper-based continuous-flow microfluidic (p-CMF) devices and paper-based digital microfluidic (p-DMF) devices, for biomarker detection. First, we discuss the methods used to fabricate these two types of paper-based microfluidic devices and the strategies for programming fluid delivery and for droplet manipulation. Next, we discuss the use of these programmable paper-based devices for the single- and multi-step detection of biomarkers. Finally, we present the current limitations of paper-based microfluidics for biomarker detection and the outlook for their development.

Sensing Uric Acid with Bimetallic Nano Ag-Pt Particles

2013 ◽  
Vol 543 ◽  
pp. 72-75
Author(s):  
Balakrishnan Karthikeyan ◽  
Marimuthu Murugavelu
Keyword(s):  
Uric Acid ◽  
High Surface ◽  
Chemical Properties ◽  
Major Product ◽  
Physical And Chemical Properties ◽  
Sensing Applications ◽  
Wide Range ◽  
Good Biocompatibility ◽  
Physical And Chemical ◽  
And Chemical Properties

The emergence of nanoparticles (NPs) has opened new opportunities in analytical chemistry [. These NPs exhibit different properties and functionalities when compared to monometallic particles. In particular, they show enhanced selectivity and reactivity when used as catalysts and sensors [2-. The NPs have large surface area, high surface free energy, good biocompatibility and suitability, and it has been used in constructing electrochemical biosensors [7, . The fascinating physical and chemical properties of NPs offer excellent prospects for a wide range of bio sensing applications [ . Uric acid (UA) is the principal final product of purine metabolism in the human body [1. It has been shown that extreme abnormalities of UA levels are symptoms of several diseases (e.g. gout, hyper uricaemia and LeschNyhan syndrome)[11,1.In general, electro active UA can be irreversibly oxidized in aqueous solution and the major product is allantoin [1. In continuation of our interest with the bimetal nanoparticle (BNP) sensing here in this study, we employed Ag/Pt BNPs for detecting of UA.

Nanocomposite based on restacked crystallites of β-NiS and Ppy for the determination of theophylline and uric acid on screen-printed electrodes

2019 ◽  
Vol 43 (48) ◽  
pp. 19397-19407
Author(s):  
P. Muthukumaran ◽  
R. Ramya ◽  
P. Thivya ◽  
J. Wilson ◽  
G. Ravi
Keyword(s):  
Uric Acid ◽  
Electrocatalytic Activity ◽  
High Sensitivity ◽  
Screen Printed Electrodes ◽  
Screen Printed

We synthesized calcinated β-NiS with a highly crystalline porous nature and mixed it with Ppy to prepare a nanocomposite, which exhibited high electrocatalytic activity and this was then used to detect theophylline and uric acid with high sensitivity and stability.

High Sensitivity Polymer Photosensors for Image Sensing Applications

1998 ◽  
Vol 508 ◽  
Author(s):  
Gang Yu ◽  
Jian Wang ◽  
Jon McElvain ◽  
Alan J. Heeger
Keyword(s):  
Dynamic Range ◽  
Spectral Response ◽  
Polymeric Materials ◽  
High Sensitivity ◽  
Large Area ◽  
Image Sensing ◽  
Sensing Applications ◽  
Large Size ◽  
Photodiode Arrays ◽  
High Photosensitivity

AbstractConjugated polymers and polymer blends were developed for photosensing applications. Large size photosensors fabricated in ITO/polymer/metal configuration show high photosensitivity, 0.1-0.4 A/Watt in visible and near UV, as good as that made with inorganic semiconductors. The processability of the polymeric materials allows these photosensors be made in large size, onto substrates in desire shape, or even in flexible form, hybridized or integrated with optical devices or electronic devices. Large area, full-color, digital image sensing is demonstrated using photodiode arrays made from semiconducting polymers. The photodiode arrays, fabricated by casting the semiconducting polymer from solution at room temperature, have high photosensitivity, low dark current and large dynamic range. Photo-detection with desired spectral response or multi-band selection are also demonstrated.

scholarly journals Simulation and Optimization of SNAP-Taper Coupling System in Displacement Sensing

Sensors ◽  
2021 ◽  
Vol 21 (9) ◽  
pp. 2947
Author(s):  
Jian Chen ◽  
Yongchao Dong ◽  
Han Wang ◽  
Penghui Sun ◽  
Xueliang Zeng
Keyword(s):  
High Sensitivity ◽  
Resonance Wavelength ◽  
Displacement Sensor ◽  
Sensitivity Threshold ◽  
Simulation And Optimization ◽  
Sensing Applications ◽  
Coupling System ◽  
Surface Plot ◽  
Wide Range ◽  
Coupling Parameters

Sensing applications based on whispering gallery mode (WGM) microcavities have attracted extensive attention recently, especially in displacement sensing applications. However, the traditional displacement sensing scheme based on shift in a single resonance wavelength, has a lot of drawbacks. Herein, a novel displacement sensing scheme based on the surface nanoscale axial photonics (SNAP) is proposed to achieve a wide range and high-resolution displacement sensor through analyzing the transmittance of multiple axial modes. By analyzing the surface plot of the resonance spectrum with different coupling positions, the ideal coupling parameters and ERV for displacement sensing are obtained. In the following, displacement sensing with high sensitivity and a wide range is theoretically realized through adjusting the sensitivity threshold and the number of modes. Finally, we present our views on the current challenges and the future development of the displacement sensing based on an SNAP resonator. We believe that a comprehensive understanding on this sensing scheme would significantly contribute to the advancement of the SNAP resonator for a broad range of applications.

scholarly journals Graphene and its Derivatives-Based Optical Sensors

2021 ◽  
Vol 9 ◽  
Author(s):  
Xiao-Guang Gao ◽  
Ling-Xiao Cheng ◽  
Wen-Shuai Jiang ◽  
Xiao-Kuan Li ◽  
Fei Xing
Keyword(s):  
Optical Sensors ◽  
Low Cost ◽  
High Sensitivity ◽  
Fast Response ◽  
Cell Detection ◽  
Single Cell Detection ◽  
Sensing Applications ◽  
Wide Range ◽  
Surface Enhanced Raman ◽  
Recent Developments

Being the first successfully prepared two-dimensional material, graphene has attracted extensive attention from researchers due to its excellent properties and extremely wide range of applications. In particular, graphene and its derivatives have displayed several ideal properties, including broadband light absorption, ability to quench fluorescence, excellent biocompatibility, and strong polarization-dependent effects, thus emerging as one of the most popular platforms for optical sensors. Graphene and its derivatives-based optical sensors have numerous advantages, such as high sensitivity, low-cost, fast response time, and small dimensions. In this review, recent developments in graphene and its derivatives-based optical sensors are summarized, covering aspects related to fluorescence, graphene-based substrates for surface-enhanced Raman scattering (SERS), optical fiber biological sensors, and other kinds of graphene-based optical sensors. Various sensing applications, such as single-cell detection, cancer diagnosis, protein, and DNA sensing, are introduced and discussed systematically. Finally, a summary and roadmap of current and future trends are presented in order to provide a prospect for the development of graphene and its derivatives-based optical sensors.

A Comparative Analysis of Iridium Oxide Nanowires in Electrical Detection of Biochemical Reactions

2008 ◽  
Vol 1095 ◽  
Author(s):  
Vinu Venkatraman ◽  
Ravikiran Reddy ◽  
Fengyan Zhang ◽  
David Evans ◽  
Sheng-Teng Hsu ◽  
...  
Keyword(s):  
Performance Metrics ◽  
Physical Adsorption ◽  
Chemical Properties ◽  
Precious Metals ◽  
High Sensitivity ◽  
Iridium Oxide ◽  
Biomolecular Sensing ◽  
Reactive Protein ◽  
Sensing Applications ◽  
Inflammatory Protein

AbstractPt, Ir, Au and few other precious metals have highly conducive electrical and chemical properties; hence have been widely used in pH sensors and bimolecular sensing applications. The chief objective of this research is to highlight and demonstrate the advantages that Iridium Oxide (IrOx) nanowires offer over these competing metals in improving the performance metrics of biomolecular sensing. Iridium oxide has very good conductivity and very high charge storing capacity, and hence has an ability to detect very small changes in the surface charge. Nanowires have an ideal morphology to crowd protein molecules and highly increase the surface area of interaction. Higher area of interaction along with iridium oxide's high intrinsic physical adsorption rate, strongly enhance the rate of immobilization of biomolecules and hence enabling high sensitivity detection. Inflammatory protein, C-Reactive protein (CRP) that is a biomarker for cardiovascular disease was used as the model biomolecule for this study.

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