scholarly journals Grafting of Diazonium Salts on Surfaces: Application to Biosensors

Biosensors ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 4 ◽  
Author(s):  
Dardan Hetemi ◽  
Vincent Noël ◽  
Jean Pinson
Keyword(s):  
Surface Modification ◽  
Nucleic Acids ◽  
Small Molecules ◽  
Diazonium Salts ◽  
Recent Advances ◽  
Biological Interest

This review is divided into two parts; the first one summarizes the main features of surface modification by diazonium salts with a focus on most recent advances, while the second part deals with diazonium-based biosensors including small molecules of biological interest, proteins, and nucleic acids.

scholarly journals Prebiotic Reaction Networks in Water

Life ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 352
Author(s):  
Quoc Phuong Tran ◽  
Zachary R. Adam ◽  
Albert C. Fahrenbach
Keyword(s):  
Nucleic Acids ◽  
Small Molecules ◽  
Prebiotic Chemistry ◽  
Origins Of Life ◽  
Network Evolution ◽  
System Level ◽  
Reaction Networks ◽  
Polymeric Networks ◽  
Recent Advances ◽  
The Future

A prevailing strategy in origins of life studies is to explore how chemistry constrained by hypothetical prebiotic conditions could have led to molecules and system level processes proposed to be important for life’s beginnings. This strategy has yielded model prebiotic reaction networks that elucidate pathways by which relevant compounds can be generated, in some cases, autocatalytically. These prebiotic reaction networks provide a rich platform for further understanding and development of emergent “life-like” behaviours. In this review, recent advances in experimental and analytical procedures associated with classical prebiotic reaction networks, like formose and Miller-Urey, as well as more recent ones are highlighted. Instead of polymeric networks, i.e., those based on nucleic acids or peptides, the focus is on small molecules. The future of prebiotic chemistry lies in better understanding the genuine complexity that can result from reaction networks and the construction of a centralised database of reactions useful for predicting potential network evolution is emphasised.

Structural Insights into the Recognition of DNA Defects by Small Molecules

2021 ◽  
Author(s):  
David Dayanidhi Paul Elisa Sundar ◽  
Vaidyanathan Ganesan
Keyword(s):  
Nucleic Acids ◽  
Metal Complexes ◽  
Small Molecules ◽  
Chemical Properties ◽  
Biological Applications ◽  
Binding Interaction ◽  
Structural Insights

Studies on the binding interaction of small molecules and nucleic acids have been explored for their biological applications. With excellent photophysical/chemical properties, numerous metal complexes have been studied as structural...

Recent advances in the analysis of fetal nucleic acids in maternal plasma

2012 ◽  
Vol 19 (6) ◽  
pp. 462-468 ◽  
Author(s):  
Nancy Bo Yin Tsui ◽  
Yuk Ming Dennis Lo
Keyword(s):  
Nucleic Acids ◽  
Maternal Plasma ◽  
Recent Advances

scholarly journals A Mini Review: Recent Advances in Surface Modification of Porous Silicon

Materials ◽  
2018 ◽  
Vol 11 (12) ◽  
pp. 2557 ◽  
Author(s):  
Seo Lee ◽  
Jae Kang ◽  
Dokyoung Kim
Keyword(s):  
Surface Modification ◽  
Porous Silicon ◽  
Wide Spectrum ◽  
Basic Research ◽  
Recent Advances ◽  
Developed Surface ◽  
The Many ◽  
Insight Into ◽  
Biomedical Fields

Porous silicon has been utilized within a wide spectrum of industries, as well as being used in basic research for engineering and biomedical fields. Recently, surface modification methods have been constantly coming under the spotlight, mostly in regard to maximizing its purpose of use. Within this review, we will introduce porous silicon, the experimentation preparatory methods, the properties of the surface of porous silicon, and both more conventional as well as newly developed surface modification methods that have assisted in attempting to overcome the many drawbacks we see in the existing methods. The main aim of this review is to highlight and give useful insight into improving the properties of porous silicon, and create a focused description of the surface modification methods.

scholarly journals Fluorinated molecular beacons as functional DNA nanomolecules for cellular imaging

2017 ◽  
Vol 8 (10) ◽  
pp. 7082-7086 ◽  
Author(s):  
Cheng Jin ◽  
Ting Fu ◽  
Ruowen Wang ◽  
Hui Liu ◽  
Jianmei Zou ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Small Molecules ◽  
Cellular Imaging ◽  
Molecular Beacons ◽  
Functional Dna

Molecular beacons (MBs) are simple, but practical, fluorescent nanoprobes widely used to detect small molecules, nucleic acids and proteins.

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