scholarly journals Influence of Impeller Speed Patterns on Hemodynamic Characteristics and Hemolysis of the Blood Pump

2019 ◽  
Vol 9 (21) ◽  
pp. 4689 ◽  
Author(s):  
Yiwen Wang ◽  
Peng Shen ◽  
Minli Zheng ◽  
Pengqiang Fu ◽  
Lijia Liu ◽  
...  
Keyword(s):  
Pulsating Flow ◽  
Constant Speed ◽  
Lumped Parameter Model ◽  
Blood Pump ◽  
Impeller Speed ◽  
Hydrodynamic Characteristics ◽  
Rotary Blood Pump ◽  
Arterial Blood ◽  
Speed Modulation ◽  
Hemodynamic Characteristics

A continuous-flow output mode of a rotary blood pump reduces the fluctuation range of arterial blood pressure and easily causes complications. For a centrifugal rotary blood pump, sinusoidal and pulsatile speed patterns are designed using the impeller speed modulation. This study aimed to analyze the hemodynamic characteristics and hemolysis of different speed patterns of a blood pump in patients with heart failure using computational fluid dynamics (CFD) and the lumped parameter model (LPM). The results showed that the impeller with three speed patterns (including the constant speed pattern) met the normal blood demand of the human body. The pulsating flow generated by the impeller speed modulation effectively increased the maximum pulse pressure (PP) to 12.7 mm Hg, but the hemolysis index (HI) in the sinusoidal and pulsatile speed patterns was higher than that in the constant speed pattern, which was about 2.1 × 10−5. The flow path of the pulsating flow field in the spiral groove of the hydrodynamic suspension bearing was uniform, but the alternating high shear stress (0~157 Pa) was caused by the impeller speed modulation, causing blood damage. Therefore, the rational modulation of the impeller speed and the structural optimization of a blood pump are important for improving hydrodynamic characteristics and hemolysis.

Speed Modulation of the HeartWare HVAD to Assess In Vitro Hemocompatibility of Pulsatile and Continuous Flow Regimes in a Rotary Blood Pump

2018 ◽  
Vol 42 (9) ◽  
pp. 879-890 ◽  
Author(s):  
Jarod T. Horobin ◽  
Michael J. Simmonds ◽  
Deepika Nandakumar ◽  
Shaun D. Gregory ◽  
Geoff Tansley ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Flow Regimes ◽  
Blood Pump ◽  
Rotary Blood Pump ◽  
Speed Modulation

Noninvasive assessment of blood pressure in rotary blood pump recipients using a novel ultrasonic Doppler method

2019 ◽  
Vol 42 (5) ◽  
pp. 226-232
Author(s):  
Marcus Granegger ◽  
Bente Thamsen ◽  
Francesco Moscato ◽  
Thomas Schlöglhofer ◽  
Christoph Gross ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Radial Artery ◽  
Blood Pump ◽  
Arterial Line ◽  
Rotary Blood Pump ◽  
Flow Measurements ◽  
Velocity Signal ◽  
Doppler Method ◽  
Arterial Blood ◽  
The Mean

In rotary blood pump recipients with low blood pressure pulsatility, current oscillometric methods to measure blood pressure are not applicable. The aim of this study was to use ultrasonic Doppler flow measurements to determine blood pressure in this patient population noninvasively. In 28 rotary blood pump recipients, blood pressure was measured three times with the developed Doppler method and compared to the invasive arterial line (n = 15) or to the oscillometric Terumo Elemano BP monitor (n = 13). Blood velocities in the radial artery were recorded by the new Doppler sensor during cuff deflation. A sigmoid curve was fitted to a preprocessed velocity signal and the systolic and mean arterial pressures were determined. A total of 84 measurements were performed, and 17 recordings were visually excluded from further analysis due to obvious artifacts. Both the systolic and mean pressures derived by the Doppler method were in good accordance with the invasively measured pressure (3.7 ± 6.6 mmHg for the systolic and −2.1 ± 7.3 mmHg for the mean pressure). A good agreement between the oscillometric monitor and the Doppler method for the systolic (0.0 ± 6.0 mmHg) and mean (1.0 ± 5.9 mmHg) pressures was observed. In this study, a new Doppler blood pressure measurement system was developed and clinically validated. The novel sensor allows easier placement above the radial artery compared to commercial probes. An algorithm was developed which processes the Doppler signal robustly and is able to determine the systolic as well as the mean arterial blood pressure.

scholarly journals The Influence of Rotary Blood Pump Speed Modulation on the Risk of Intraventricular Thrombosis

2018 ◽  
Vol 42 (10) ◽  
pp. 943-953 ◽  
Author(s):  
Sam Liao ◽  
Eric L. Wu ◽  
Michael Neidlin ◽  
Zhiyong Li ◽  
Benjamin Simpson ◽  
...  
Keyword(s):  
Blood Pump ◽  
Rotary Blood Pump ◽  
Pump Speed ◽  
Speed Modulation

scholarly journals Asymmetric speed modulation of a rotary blood pump affects ventricular unloading

2012 ◽  
Vol 43 (2) ◽  
pp. 383-388 ◽  
Author(s):  
Tohid Pirbodaghi ◽  
Alberto Weber ◽  
Shannon Axiak ◽  
Thierry Carrel ◽  
Stijn Vandenberghe
Keyword(s):  
Blood Pump ◽  
Rotary Blood Pump ◽  
Speed Modulation

Effects of the Design of a Rotary Blood Pump on Hemocompatibility

2021 ◽  
Author(s):  
M. V. Denisov ◽  
M. Walter ◽  
S. Leonhard ◽  
D. V. Telyshev
Keyword(s):  
Blood Pump ◽  
Rotary Blood Pump

Development of Rotary Blood Pump Technology: Past, Present, and Future

2000 ◽  
Vol 24 (6) ◽  
pp. 412-420 ◽  
Author(s):  
Yukihiko Nosé ◽  
M. Yoshikawa ◽  
S. Murabayashi ◽  
T. Takano
Keyword(s):  
Blood Pump ◽  
Rotary Blood Pump

scholarly journals 3D Printing of Functional Assemblies with Integrated Polymer-Bonded Magnets Demonstrated with a Prototype of a Rotary Blood Pump

2018 ◽  
Vol 8 (8) ◽  
pp. 1275 ◽  
Author(s):  
Kai von Petersdorff-Campen ◽  
Yannick Hauswirth ◽  
Julia Carpenter ◽  
Andreas Hagmann ◽  
Stefan Boës ◽  
...  
Keyword(s):  
Fused Deposition Modeling ◽  
Permanent Magnets ◽  
Low Cost ◽  
Magnetic Bearing ◽  
Blood Pump ◽  
Rotary Blood Pump ◽  
Pump Impeller ◽  
Fused Deposition ◽  
Magnetic Components ◽  
Deposition Modeling

Conventional magnet manufacturing is a significant bottleneck in the development processes of products that use magnets, because every design adaption requires production steps with long lead times. Additive manufacturing of magnetic components delivers the opportunity to shift to agile and test-driven development in early prototyping stages, as well as new possibilities for complex designs. In an effort to simplify integration of magnetic components, the current work presents a method to directly print polymer-bonded hard magnets of arbitrary shape into thermoplastic parts by fused deposition modeling. This method was applied to an early prototype design of a rotary blood pump with magnetic bearing and magnetic drive coupling. Thermoplastics were compounded with 56 vol.% isotropic NdFeB powder to manufacture printable filament. With a powder loading of 56 vol.%, remanences of 350 mT and adequate mechanical flexibility for robust processability were achieved. This compound allowed us to print a prototype of a turbodynamic pump with integrated magnets in the impeller and housing in one piece on a low-cost, end-user 3D printer. Then, the magnetic components in the printed pump were fully magnetized in a pulsed Bitter coil. The pump impeller is driven by magnetic coupling to non-printed permanent magnets rotated by a brushless DC motor, resulting in a flow rate of 3 L/min at 1000 rpm. For the first time, an application of combined multi-material and magnet printing by fused deposition modeling was shown. The presented process significantly simplifies the prototyping of products that use magnets, such as rotary blood pumps, and opens the door for more complex and innovative designs. It will also help postpone the shift to conventional manufacturing methods to later phases of the development process.

Effect of Tubing Length Pump on Flow Derived Index During Rotary Blood Pump Support

2017 ◽  
Author(s):  
Thananya Khienwad ◽  
Ronnachit Deepankaew ◽  
Praemai Wannawat ◽  
Phornphop Naiyanetr
Keyword(s):  
Blood Pump ◽  
Rotary Blood Pump
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