scholarly journals The Influence of Rotary Blood Pump Speed Modulation on the Risk of Intraventricular Thrombosis

2018 ◽  
Vol 42 (10) ◽  
pp. 943-953 ◽  
Author(s):  
Sam Liao ◽  
Eric L. Wu ◽  
Michael Neidlin ◽  
Zhiyong Li ◽  
Benjamin Simpson ◽  
...  
2018 ◽  
Vol 42 (9) ◽  
pp. 879-890 ◽  
Author(s):  
Jarod T. Horobin ◽  
Michael J. Simmonds ◽  
Deepika Nandakumar ◽  
Shaun D. Gregory ◽  
Geoff Tansley ◽  
...  

2004 ◽  
Vol 28 (7) ◽  
pp. 660-667 ◽  
Author(s):  
Stijn Vandenberghe ◽  
Takahiro Nishida ◽  
Patrick Segers ◽  
Bart Meyns ◽  
Pascal Verdonck

1999 ◽  
Vol 23 (8) ◽  
pp. 797-801 ◽  
Author(s):  
Takehide Akimoto ◽  
Kenji Yamazaki ◽  
Philip Litwak ◽  
Kenneth N. Litwak ◽  
Osamu Tagusari ◽  
...  

2019 ◽  
Vol 9 (21) ◽  
pp. 4689 ◽  
Author(s):  
Yiwen Wang ◽  
Peng Shen ◽  
Minli Zheng ◽  
Pengqiang Fu ◽  
Lijia Liu ◽  
...  

A continuous-flow output mode of a rotary blood pump reduces the fluctuation range of arterial blood pressure and easily causes complications. For a centrifugal rotary blood pump, sinusoidal and pulsatile speed patterns are designed using the impeller speed modulation. This study aimed to analyze the hemodynamic characteristics and hemolysis of different speed patterns of a blood pump in patients with heart failure using computational fluid dynamics (CFD) and the lumped parameter model (LPM). The results showed that the impeller with three speed patterns (including the constant speed pattern) met the normal blood demand of the human body. The pulsating flow generated by the impeller speed modulation effectively increased the maximum pulse pressure (PP) to 12.7 mm Hg, but the hemolysis index (HI) in the sinusoidal and pulsatile speed patterns was higher than that in the constant speed pattern, which was about 2.1 × 10−5. The flow path of the pulsating flow field in the spiral groove of the hydrodynamic suspension bearing was uniform, but the alternating high shear stress (0~157 Pa) was caused by the impeller speed modulation, causing blood damage. Therefore, the rational modulation of the impeller speed and the structural optimization of a blood pump are important for improving hydrodynamic characteristics and hemolysis.


2012 ◽  
Vol 43 (2) ◽  
pp. 383-388 ◽  
Author(s):  
Tohid Pirbodaghi ◽  
Alberto Weber ◽  
Shannon Axiak ◽  
Thierry Carrel ◽  
Stijn Vandenberghe

Author(s):  
M. V. Denisov ◽  
M. Walter ◽  
S. Leonhard ◽  
D. V. Telyshev
Keyword(s):  

2000 ◽  
Vol 24 (6) ◽  
pp. 412-420 ◽  
Author(s):  
Yukihiko Nosé ◽  
M. Yoshikawa ◽  
S. Murabayashi ◽  
T. Takano
Keyword(s):  

2018 ◽  
Vol 8 (8) ◽  
pp. 1275 ◽  
Author(s):  
Kai von Petersdorff-Campen ◽  
Yannick Hauswirth ◽  
Julia Carpenter ◽  
Andreas Hagmann ◽  
Stefan Boës ◽  
...  

Conventional magnet manufacturing is a significant bottleneck in the development processes of products that use magnets, because every design adaption requires production steps with long lead times. Additive manufacturing of magnetic components delivers the opportunity to shift to agile and test-driven development in early prototyping stages, as well as new possibilities for complex designs. In an effort to simplify integration of magnetic components, the current work presents a method to directly print polymer-bonded hard magnets of arbitrary shape into thermoplastic parts by fused deposition modeling. This method was applied to an early prototype design of a rotary blood pump with magnetic bearing and magnetic drive coupling. Thermoplastics were compounded with 56 vol.% isotropic NdFeB powder to manufacture printable filament. With a powder loading of 56 vol.%, remanences of 350 mT and adequate mechanical flexibility for robust processability were achieved. This compound allowed us to print a prototype of a turbodynamic pump with integrated magnets in the impeller and housing in one piece on a low-cost, end-user 3D printer. Then, the magnetic components in the printed pump were fully magnetized in a pulsed Bitter coil. The pump impeller is driven by magnetic coupling to non-printed permanent magnets rotated by a brushless DC motor, resulting in a flow rate of 3 L/min at 1000 rpm. For the first time, an application of combined multi-material and magnet printing by fused deposition modeling was shown. The presented process significantly simplifies the prototyping of products that use magnets, such as rotary blood pumps, and opens the door for more complex and innovative designs. It will also help postpone the shift to conventional manufacturing methods to later phases of the development process.


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