scholarly journals Ground-Borne Vibration Due to Construction Works with Respect to Brownfield Areas

2019 ◽  
Vol 9 (18) ◽  
pp. 3766 ◽  
Author(s):  
Martin Stolarik ◽  
Miroslav Pinka ◽  
Jan Nedoma
Keyword(s):  
Adverse Effects ◽  
Central Europe ◽  
Theoretical Study ◽  
Original Data ◽  
Seismic Load ◽  
Industrial Cities ◽  
Wide Range ◽  
Post Industrial ◽  
Seismic Measurements ◽  
Construction Works

Ground-borne vibration caused by mechanized construction works is the most common problem in built-up areas in general. In post-industrial cities, there are many building facilities in the category of brownfields. Parts of these buildings are often technically and culturally valuable buildings with varying degrees of decay. These are very susceptible to vibrations. The revitalization of brownfield areas employs a wide range of works and practices, among which are those that have adverse effects in the form of vibrations and shocks. This paper presents a theoretical study and original results concerning the seismic load on historical and dilapidated buildings in brownfield areas due to the ground-borne vibration caused by mechanized construction works. Original data from seismic measurements are related to the post-industrial Ostrava agglomeration, in the area of one of the biggest successfully revitalized brownfields in Central Europe. All measurements were evaluated in terms of both amplitude and frequency. The results of all measurements were processed in the form of attenuation curves.

scholarly journals The Romano–Wolf multiple-hypothesis correction in Stata

2020 ◽  
Vol 20 (4) ◽  
pp. 812-843
Author(s):  
Damian Clarke ◽  
Joseph P. Romano ◽  
Michael Wolf
Keyword(s):  
Error Rate ◽  
Multiple Testing ◽  
Original Data ◽  
Dependence Structure ◽  
Familywise Error Rate ◽  
Testing Procedures ◽  
Multiple Testing Procedures ◽  
Multiple Hypothesis ◽  
Wide Range ◽  
Performance Gains

When considering multiple-hypothesis tests simultaneously, standard statistical techniques will lead to overrejection of null hypotheses unless the multiplicity of the testing framework is explicitly considered. In this article, we discuss the Romano–Wolf multiple-hypothesis correction and document its implementation in Stata. The Romano–Wolf correction (asymptotically) controls the familywise error rate, that is, the probability of rejecting at least one true null hypothesis among a family of hypotheses under test. This correction is considerably more powerful than earlier multiple-testing procedures, such as the Bonferroni and Holm corrections, given that it takes into account the dependence structure of the test statistics by resampling from the original data. We describe a command, rwolf, that implements this correction and provide several examples based on a wide range of models. We document and discuss the performance gains from using rwolf over other multiple-testing procedures that control the familywise error rate.

scholarly journals Adriamycin - efficacy and possible adverse effects

2016 ◽  
Vol 17 (1) ◽  
pp. 38-46 ◽  
Author(s):  
Agnieszka Pedrycz ◽  
Agnieszka Kramkowska
Keyword(s):  
Adverse Effects ◽  
Topoisomerase I ◽  
Myocardial Injury ◽  
Initial Level ◽  
Chemical Substance ◽  
Bilayer Membrane ◽  
Anticancer Effects ◽  
Wide Range ◽  
Knowledge Of Cancer ◽  
Pegylated Form

AbstractAdriamycin (doxorubicin) is a chemical substance in the anthracycline class with a wide range of applications in oncology and hematology. The mechanism of action of Adriamycin is related to formation of irregular bonds between nucleobases of DNA and inhibition of key enzymes of DNA synthesis - topoisomerase I and II as well as to formation of free radicals damaging DNA.A major limitation in the drug use is associated with its adverse effects such as cardiotoxicity and hepatotoxicity.The mechanism of myocardial injury by Adriamycin is linked to an increase in oxidative stress associated with impaired mitochondrial function and structure.Cardiotoxicity of anthracyclines is classified as: acute, chronic or late (delayed).Hepatotoxicity of Adriamycin as a damage of the liver is associated with a dysfunction of this organ. Adriamycin studies have shown increased level of transaminase present in 40% of patients treated with Adriamycin. The state was transient and asymptomatic, returning to the initial level even when treatment continued.Knowledge of cancer diseases contributed to a successive creation of two improved forms of Adriamycin (doxorubicin) – nonpegylated and pegylated formulas of the drug.The mechanism of anticancer effects of liposomal Adriamycin is similar to the mechanism of conventional Adriamycin, but placement of the molecules of active substance in liposomes has significant influence on the distribution of the drug.In order to increase the distribution of the drug, a special form of liposomal Adriamycin has been created by covering the surface of the liposomes with a hydrophilic polymer - (MPEG). This process, known as pegylation, decreases the interactions between the lipid bilayer membrane and the plasma components. Pegylated form of the drug is associated with a higher incidence of acute complications.

scholarly journals Poland and New Trends in Central European Regional Configuration

2021 ◽  
Vol 101 (1) ◽  
pp. 52-61
Author(s):  
Maria Rusakova ◽  
Keyword(s):  
Baltic Sea ◽  
Central Europe ◽  
Regional Integration ◽  
The Baltic Sea ◽  
Central European ◽  
Eastern Partnership ◽  
Carpathian Region ◽  
Wide Range ◽  
The Baltic ◽  
European Regional

The article examines Warsaw's attempts to expand its influence in Central Europe by initiating various regional integration projects: cooperation with the Baltic sea countries participation in the development of the Carpathian region the newest format – the Lublin Triangle. The content of the Lublin Declaration signed on July 28, 2020 by Lithuania, Poland and Ukraine is analyzed in detail. Having been convinced by the example of Ukraine that the Eastern Partnership policy does not allow for quick results, as well as in connection with the events in Belarus, Poland decided to create a regional initiative that can be considered as a continuation of the Eastern Partnership policy. The Lublin Declaration opens up a wide range of potential areas of cooperation, however it is still too early to say how successful this project will be. Initially it was planned that Belarus would also join the Lublin Initiative, but later Minsk refused to participate. This seriously limited the project, but does not exclude the possibility of future innovations in its format. The author concludes that the Lublin Triangle is one of the Warsaw's instruments to realize the idea of Intermarium

scholarly journals Clinical benefits and adverse effects of siwak (S. persica) use on periodontal health: a scoping review of literature

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Haslinda Ramli ◽  
Tuti Ningseh Mohd-Dom ◽  
Shahida Mohd-Said
Keyword(s):  
Adverse Effects ◽  
Scoping Review ◽  
Oral Hygiene ◽  
English Language ◽  
Final Analysis ◽  
Clinical Effectiveness ◽  
Periodontal Health ◽  
Clinical Attachment Loss ◽  
Tooth Cleaning ◽  
Wide Range

Abstract Background Siwak is a chewing stick used as an oral hygiene aid associated with Muslim communities across the globe since more than 1500 years ago. Used either exclusively or in conjunction with a regular toothbrush, there is evidence supporting its clinical effectiveness in plaque control, but adverse effects on periodontal health remains inconclusive. Objective This study aims to systematically review the wide range of data and literatures related to siwak practice and its effect on periodontal health. Method The review was conducted based on scoping review techniques, searching literature in EBSCOHOST, PubMed, SCOPUS and Google scholar databases using the following search terms: “siwak’ or ‘miswak’ or ‘chewing stick” for intervention, and “periodontium or ‘periodontal’ or ‘periodontal health’ or ‘periodontal disease” for outcome. Articles published between January 1990 to March 2021 and written in English language were included. Results A total of 721 articles collected from the search and 21 of them were eligible for the final analysis. Results of this study was described based on clinical and antibacterial reporting of siwak, method of siwak practice and its adverse effect on oral health. Siwak was found effective at removing dental plaque and improving periodontal health over time although its effect on subgingival microbiota was inconclusive. Presence of gingival recession and clinical attachment loss were much more commonly reported in siwak users, attributable to variations in the methods employed for tooth cleaning using the siwak. Conclusion There is substantial evidence that the lack of standardised reporting for effective siwak use may have resulted in contradictory findings about its oral hygiene benefits and adverse effects. As such, future work on safe and effective siwak practice is to be advocated among its users.

Latin American Connections: Recent Work on German Interactions with Latin America

2013 ◽  
Vol 46 (2) ◽  
pp. 362-394 ◽  
Author(s):  
H. Glenn Penny
Keyword(s):  
Latin America ◽  
Sixteenth Century ◽  
South America ◽  
Early Modern ◽  
Central Europe ◽  
Latin American ◽  
Mining Operations ◽  
Almost Everywhere ◽  
Wide Range ◽  
German Speaking

German interactions with Latin America have a long history. Indeed, early modern historians have demonstrated that people from German-speaking central Europe took part in all aspects of the European conquest of Central and South America. They have shown that these people were critical to mining operations and publishing in sixteenth-century Mexico; they have found them among Portuguese and Spanish sailors and soldiers almost everywhere; and they have located them playing important roles in a wide range of professions from Mexico to the south of Chile.

A brief review on the erosion-corrosion behavior of engineering materials

2018 ◽  
Vol 36 (5) ◽  
pp. 435-447 ◽  
Author(s):  
Roshan Kuruvila ◽  
S. Thirumalai Kumaran ◽  
M. Adam Khan ◽  
M. Uthayakumar
Keyword(s):  
Adverse Effects ◽  
Industrial Process ◽  
Industrial Applications ◽  
Appropriate Technology ◽  
Material Loss ◽  
Adverse Conditions ◽  
Wide Range ◽  
Erosion Corrosion ◽  
The Cost ◽  
Selection Of

AbstractThe efficiency of industry depends upon the working conditions of the equipment and components used in the industrial process. The biggest problems faced by the industries are the problems of erosion and corrosion. The harmful effects of corrosion will lead to material loss, which results from the degradation of the equipment. The degradation of the equipment will cause the breakdown of the plant; moreover, it is a threat to the safety of people, and also from the point of conservation, it can cause the exploitation of available resources. The cost of replacing equipment increases the expense, and it can also result in the temporary shutdown of the plant. The protection of surfaces from the adverse effects of corrosion and erosion-corrosion is a matter of great concern in most industrial applications. Advancements in technology provides a wide range of techniques to overcome adverse conditions. The selection of appropriate technology must be from the viewpoint of their interaction with the environment. This review paper addresses the adverse effects of erosion-corrosion in the present scenario.

Perspectives on phytoremediation landscaping principles for post-industrial cities

2021 ◽  
Author(s):  
Tania Mihaiescu ◽  
Roxana Vidican ◽  
Dorin Miclaus ◽  
Anca Plesa ◽  
Ioana Crisan
Keyword(s):  
Industrial Cities ◽  
Post Industrial

Nonglycemic Adverse Effects of Insulin

2021 ◽  
Vol 17 ◽  
Author(s):  
Alissa M. Guarneri ◽  
Robert P. Hoffman
Keyword(s):  
Glycemic Control ◽  
Adverse Effects ◽  
Allergic Reactions ◽  
Sodium Retention ◽  
Delivery Method ◽  
Rapid Improvement ◽  
Antibody Treatment ◽  
Wide Range ◽  
Patients With Diabetes ◽  
Patient Health

: Insulin is primarily thought of for its glycemic effects in patients with diabetes. There are, however, non-glycemic adverse effects of insulin that may significantly impact patient health and can interfere with glycemic control. Insulinogenic edema primarily occurs with rapid improvement in glycemic control either in patients with newly discovered diabetes or in patients with poorly-controlled diabetes. Insulin-induced sympathetic activation, vasodilation, changes in vascular permeability and most importantly sodium retention play significant etiologic roles in the development of edema. Clinically, it is usually self-limited but significant complications can develop. Allergic reactions to all insulin preparations and various compounds used in insulin formulations with a wide range of severity have been reported. Frequently, changing type of insulin or delivery method is sufficient, but more advanced treatments such as insulin desensitization and anti-IgE antibody treatment may be needed. Lipohypertrophy and lipoatrophy frequently develop with overuse of injection sites. Lipohypertrophy can affect tissue insulin absorption and glycemic control.

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