scholarly journals An Innovative Bioceramic Bone Graft with Platelet-Rich Plasma for Rapid Bone Healing and Regeneration in a Rabbit Model

2021 ◽  
Vol 11 (11) ◽  
pp. 5271
Author(s):  
Syamsiah Syam ◽  
Chun-Wei Chang ◽  
Wen-Chien Lan ◽  
Keng-Liang Ou ◽  
Bai-Hung Huang ◽  
...  
Keyword(s):  
Bone Graft ◽  
Maxillary Sinus ◽  
Bone Healing ◽  
Platelet Rich Plasma ◽  
Rabbit Model ◽  
Graft Material ◽  
Computed Tomographic ◽  
Hematoxylin And Eosin ◽  
The Right

This study aimed to investigate the effect of combining an innovative bioceramic α-calcium sulfate hemihydrate (α-CSH, CaSO4⋅0.5H2O) bone graft and platelet-rich plasma (PRP) to accelerate bone healing and regeneration in a rabbit model. The bone graft material was implanted bilaterally on rabbit’s artificially maxillary sinus defects: the right maxillary sinus received α-CSH, while α-CSH combine with PRP (α-CSH/PRP) was grafted in left site. The quantity and quality of bone formation after implantation were analyzed radiographically and histologically at 1, 2, and 3 weeks. The micro-computed tomographic results indicated that the bone density of sinus implanted with α-CSH increased and defect volume decreased most after 2 weeks. In histological analysis, both hematoxylin and eosin and Masson trichrome staining of α-CSH/PRP displays better bone healing and regeneration progress than α-CSH after 2 weeks implantation. Therefore, the innovative α-CSH combined with PRP was revealed to be useful in accelerating bone healing and regeneration for the successful defect treatment.

scholarly journals Comprehensive Review of Knee Osteoarthritis Pharmacological Treatment and the Latest Professional Societies’ Guidelines

2021 ◽  
Vol 14 (3) ◽  
pp. 205
Author(s):  
Dragan Primorac ◽  
Vilim Molnar ◽  
Vid Matišić ◽  
Damir Hudetz ◽  
Željko Jeleč ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Platelet Rich Plasma ◽  
Symptom Relief ◽  
Topical Administration ◽  
Symptomatic Therapy ◽  
Therapy Options ◽  
Professional Societies ◽  
Inflammatory Drugs ◽  
The Right

Osteoarthritis is the most common musculoskeletal progressive disease, with the knee as the most commonly affected joint in the human body. While several new medications are still under research, many symptomatic therapy options, such as analgesics (opioid and non-opioid), nonsteroid anti-inflammatory drugs, symptomatic slow-acting drugs in osteoarthritis, and preparations for topical administration, are being used, with a diverse clinical response and inconsistent conclusions across various professional societies guidelines. The concept of pharmacogenomic-guided therapy, which lies on principles of the right medication for the right patient in the right dose at the right time, can significantly increase the patient’s response to symptom relief therapy in knee osteoarthritis. Corticosteroid intra-articular injections and hyaluronic acid injections provoke numerous discussions and disagreements among different guidelines, even though they are currently used in daily clinical practice. Biological options, such as platelet-rich plasma and mesenchymal stem cell injections, have shown good results in the treatment of osteoarthritis symptoms, greatly increasing the patient’s quality of life, especially when combined with other therapeutic options. Non-inclusion of the latter therapies in the guidelines, and their inconsistent stance on numerous therapy options, requires larger and well-designed studies to examine the true effects of these therapies and update the existing guidelines.

Influence of the proportion of particulate autogenous bone graft/platelet-rich plasma on bone healing in critical-size defects

Bone ◽  
2009 ◽  
Vol 45 (2) ◽  
pp. 339-345 ◽  
Author(s):  
Maria Nagata ◽  
Michel Messora ◽  
Roberta Okamoto ◽  
Natália Campos ◽  
Natália Pola ◽  
...  
Keyword(s):  
Bone Graft ◽  
Bone Healing ◽  
Critical Size ◽  
Platelet Rich Plasma ◽  
Autogenous Bone Graft ◽  
Autogenous Bone ◽  
Critical Size Defects

scholarly journals Computed Tomographic Evaluation of Bone Quality of the Mandible Reconstructed by Particular Cellular Bone and Marrow Combined with Platelet Rich Plasma

2009 ◽  
Vol 6 (2) ◽  
pp. 63-72 ◽  
Author(s):  
Muneharu Iwamoto ◽  
Akira Matsuo ◽  
Noriko Kato ◽  
Sawako Takeuchi ◽  
Hidetoshi Takahashi ◽  
...  
Keyword(s):  
Bone Quality ◽  
Platelet Rich Plasma ◽  
Computed Tomographic ◽  
Cellular Bone

scholarly journals A study on maxillary sinus dimensions by computed tomography in population of Tamil Nadu

2016 ◽  
Vol 05 (02) ◽  
pp. 091-096
Author(s):  
N Muthukumaravel ◽  
K.Y Manjunath
Keyword(s):  
Computed Tomography ◽  
Maxillary Sinus ◽  
Tamil Nadu ◽  
Maximum Width ◽  
Average Width ◽  
Computed Tomographic ◽  
Significant Difference ◽  
The Difference ◽  
The Right ◽  
Maxillary Sinuses

Abstract Background and aims: Maxillary sinuses are the largest of the paranasal sinuses known for variability in their dimensions. The maxillary sinus dimensions can be better ascertained in living by using computed tomography instead of plain radiography. This study was planned for highlighting the variations in the dimensions of the maxillary sinuses of population of Tamil Nadu region. The aims of the present study were to estimate dimensions of the maxillary sinuses on computed tomographic (CT) scan of the head of patients from Tamil Nadu and to compare the data gender wise and sidewise. Material and methods: Maximum width, height and depth of maxillary sinus of both sides were measured in CT - head images of 100 males and 100 females of 20-50 years of age in Tamil Nadu. Comparison of data between genders and sides by applying unpaired student "t" test was done. Results : The mean depth, height and width of both right and left maxillary sinuses were comparatively less in females than the males and the difference was found to be statistically significant ( P <.0001). On comparison between the sides of maxillary sinuses, the depth and the height of maxillary sinus did not show any significant difference in the measurements (p >.05), whereas the width of the left side (23.96 mm) was higher than that of the right side (23.69) and the difference was found to be statistically significant (P<.05). The combined average maxillary sinus dimensions (in mm) for both genders in the study population of Tamil Nadu are as follows: Right side depth: 33.71 ± 1.00; Left side depth : 33.65 ± 1.22; Right side height: 34.66 ± 2.71; Left side height: 34.74± 2.48; Right side width: 23.69 ± 0.78 and Left side width: 23.96 ± 0.86. Conclusion: The dimensions of maxillary sinuses in males were found to be larger than those of females and this difference was statistically significant. The average width of the maxillary sinuses on the left side is significantly more than that of right sided sinuses. Computed tomography measurements of maxillary sinuses may be useful in gender determination.

Effect of Autologous Platelet-Rich Plasma in Combination With a Biphasic Synthetic Graft Material on Bone Healing in Critical-Size Cranial Defects

2012 ◽  
Vol 23 (5) ◽  
pp. 1318-1323 ◽  
Author(s):  
Gregory Faratzis ◽  
Minas Leventis ◽  
Evanthia Chrysomali ◽  
Lubna Khaldi ◽  
Areti Eleftheriadis ◽  
...  
Keyword(s):  
Bone Healing ◽  
Critical Size ◽  
Platelet Rich Plasma ◽  
Graft Material ◽  
Synthetic Graft ◽  
Autologous Platelet Rich Plasma ◽  
Autologous Platelet

scholarly journals Clinical evaluation of platelet rich plasma when combined with an alloplastic bone graft material in the treatment of intrabony periodontal defects

2017 ◽  
Vol 4 (1) ◽  
pp. 33 ◽  
Author(s):  
Kapil Garg ◽  
Ruchi Srivastava ◽  
PushpendraKumar Verma ◽  
Anju Gautam ◽  
Vivek Tripathi ◽  
...  
Keyword(s):  
Bone Graft ◽  
Clinical Evaluation ◽  
Platelet Rich Plasma ◽  
Graft Material ◽  
Bone Graft Material
Sign in / Sign up

Export Citation Format

Share Document