scholarly journals Inhibitory Effect of Cinnamaldehyde on Main Destructive Microorganisms of Nanhai No. 1 Shipwreck

2021 ◽  
Vol 11 (11) ◽  
pp. 5262
Author(s):  
Xinduo Huang ◽  
Yeqing Han ◽  
Jing Du ◽  
Peifeng Guo ◽  
Yu Wang ◽  
...  
Keyword(s):  
Antimicrobial Agent ◽  
Song Dynasty ◽  
Antimicrobial Agents ◽  
Negative Impact ◽  
Antimicrobial Properties ◽  
Gas Diffusion ◽  
Laboratory Simulation ◽  
Diffusion Method ◽  
Bacillus Sp ◽  
Inhibitory Effects

Nanhai No. 1, a shipwreck in the Southern Song Dynasty, China, has a history of more than 800 years. It was salvaged in 2007 and is now on display in the Guangdong Maritime Silk Road Museum. Due to the fact that the hull is a wooden cultural relic and exposed to the air, the biological corrosion and biodegradation caused by microorganisms are key problems of hull protection. At present, the antimicrobial agent Euxyl® K100 (isothiazolinone) has a significant antimicrobial effect in the field, but it has a certain negative impact on the environment and archeologists. In order to reduce the use of chemical antimicrobial agents, we evaluated the inhibitory effects of cinnamaldehyde on the main destructive microorganisms of Nanhai No. 1. Cinnamaldehyde is the main active component of cinnamon, and has broad-spectrum antimicrobial properties. The paper diffusion method, gas diffusion method and minimum inhibitory concentration experiment were used to detect the inhibitory effects of cinnamaldehyde on the main microorganisms of Nanhai No. 1. We found that cinnamaldehyde had significant inhibitory effects on Bacillus tequilensis NK-NH5, Bacillus megaterium NK-NH10, Bacillus velezensis NK-NH11, Bacillus sp. NK-NH15, Bacillus sp. NK-NH16, Bacillus sp. NK-NH17, Fusariumsolani NK-NH1 and Scedosporiumapiospermum NK.W1-3. At the same time, cinnamaldehyde had more inhibitory effects on fungi than bacteria. Finally, we verified that cinnamaldehyde can effectively inhibit the growth of microorganisms in water, for storing the scattered wood blocks of the Nanhai No. 1 hull through laboratory simulation experiments. Cinnamaldehyde, as an environment-friendly antimicrobial agent, is of great significance to protecting water-saturated wooden relics from microbial corrosion and degradation in the future.

scholarly journals Antimicrobial Hexaaquacopper(II) Complexes with Novel Polyiodide Chains

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1005
Author(s):  
Zehra Edis ◽  
Radhika Raheja ◽  
Samir Haj Bloukh ◽  
Richie R. Bhandareh ◽  
Hamid Abu Sara ◽  
...  
Keyword(s):  
Antimicrobial Agent ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Antibacterial Activities ◽  
Diffusion Method ◽  
Stable Complex ◽  
In Vitro Synthesis ◽  
Iodine Release ◽  
Chain Type

The non-toxic inorganic antimicrobial agents iodine (I2) and copper (Cu) are interesting alternatives for biocidal applications. Iodine is broad-spectrum antimicrobial agent but its use is overshadowed by compound instability, uncontrolled iodine release and short-term effectiveness. These disadvantages can be reduced by forming complex-stabilized, polymeric polyiodides. In a facile, in-vitro synthesis we prepared the copper-pentaiodide complex [Cu(H2O)6(12-crown-4)5]I6 ´ 2I2, investigated its structure and antimicrobial properties. The chemical structure of the compound has been verified. We used agar well and disc-diffusion method assays against nine microbial reference strains in comparison to common antibiotics. The stable complex revealed excellent inhibition zones against C. albicans WDCM 00054, and strong antibacterial activities against several pathogens. [Cu(H2O)6(12-crown-4)5]I6 ´ 2I2 is a strong antimicrobial agent with an interesting crystal structure consisting of complexes located on an inversion center and surrounded by six 12-crown-4 molecules forming a cationic substructure. The six 12-crown-4 molecules form hydrogen bonds with the central Cu(H2O)6 . The anionic substructure is a halogen bonded polymer which is formed by formal I5− repetition units. The topology of this chain-type polyiodide is unique. The I5− repetition units can be understood as a triodide anion connected to two iodine molecules.

scholarly journals An In Vitro Study on the Antimicrobial Properties of Essential Oil Modified Resin Composite against Oral Pathogens

Materials ◽  
2020 ◽  
Vol 13 (19) ◽  
pp. 4383
Author(s):  
Barbara Lapinska ◽  
Aleksandra Szram ◽  
Beata Zarzycka ◽  
Janina Grzegorczyk ◽  
Louis Hardan ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Antifungal Activity ◽  
Antimicrobial Agents ◽  
Resin Composite ◽  
Antimicrobial Properties ◽  
In Vitro Study ◽  
Diffusion Method ◽  
Oral Pathogens

Modifying the composition of dental restorative materials with antimicrobial agents might induce their antibacterial potential against cariogenic bacteria, e.g., S.mutans and L.acidophilus, as well as antifungal effect on C.albicans that are major oral pathogens. Essential oils (EOs) are widely known for antimicrobial activity and are successfully used in dental industry. The study aimed at evaluating antibacterial and antifungal activity of EOs and composite resin material (CR) modified with EO against oral pathogens. Ten EOs (i.e., anise, cinnamon, citronella, clove, geranium, lavender, limette, mint, rosemary thyme) were tested using agar diffusion method. Cinnamon and thyme EOs showed significantly highest antibacterial activity against S.mutans and L.acidophilus among all tested EOs. Anise and limette EOs showed no antibacterial activity against S.mutans. All tested EOs exhibited antifungal activity against C.albicans, whereas cinnamon EO showed significantly highest and limette EO significantly lowest activity. Next, 1, 2 or 5 µL of cinnamon EO was introduced into 2 g of CR and microbiologically tested. The modified CR showed higher antimicrobial activity in comparison to unmodified one. CR containing 2 µL of EO showed the best antimicrobial properties against S.mutans and C.albicans, while CR modified with 1 µL of EO showed the best antimicrobial properties against L.acidophilus.

ANTIOXIDANT AND ANTIMICROBIAL PROPERTIES OF Tinospora crispa (putarwali) STEMS METHANOLIC EXTRACT

2016 ◽  
Vol 78 (11-2) ◽  
Author(s):  
Fatimatul Akmal Sulaiman ◽  
Nurfarahin Fuad ◽  
Farawahida Rahman ◽  
Anwar Iqbal ◽  
Deny Susanti Darnis
Keyword(s):  
Antimicrobial Agents ◽  
Methanolic Extract ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Antimicrobial Properties ◽  
Diffusion Method ◽  
Disc Diffusion ◽  
Disc Diffusion Method ◽  
Average Percentage ◽  
Dried Extract

Apart from being the primary source of food to other living things, plants also have medicinal value to treat various kinds of diseases. In recent years, it has been proposed that the extract from plants may be used as natural antioxidants which can help to prevent the generation of carcinogens in human body. In addition, plants also have antimicrobial agents to inhibit the growth of pathogenic microbes. This study was intended to investigate the antioxidant properties and antimicrobial activity of methanolic extract of Tinospora crispa stems extracted using soxhlet extraction method. The antimicrobial properties of T. crispa stems extract were tested using disc diffusion method against Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 11778, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Candida albicans IMR C S23/11 A and Saccharomyces cerevisiae IMR S 617/068. The antioxidant properties of the extract were investigated by using Total Phenolics Content (TPC), Total Flavonoids Content (TFC), DPPH free radical scavenging and b–carotene bleaching assays.  The TPC value was 6.12 g GAE/100 g of dried extract while the TFC value was 55.58 g QE/100 g of dried extract. The IC50 of DPPH scavenging assay for the extract and ascorbic acid were 0.21 and 0.04 mg/mL, respectively. The average percentage of b–carotene bleaching assay was 38.3 % as compared to BHT, which was 45.1%.  The disc diffusion method showed no inhibition zone against all the strains of microorganisms at all concentrations of the extracts (0.5, 1.0, 2.5 and 5.0 mg/disc). 

scholarly journals Chemically modified polystyrene co-loaded with antimicrobial agents

2021 ◽  
Vol 2120 (1) ◽  
pp. 012012
Author(s):  
Y X Koh ◽  
H L Choo ◽  
Y H Wong ◽  
C H Yeong
Keyword(s):  
Antimicrobial Agent ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Silver Ions ◽  
Exchange Capacity ◽  
Secondary Process ◽  
Ionic Exchange ◽  
Bacterial Strains ◽  
Surgical Guides ◽  
Antimicrobial Material

Abstract A recent study showed that at least 50% of nosocomial infections are due to medical indwelling devices like surgical guides and prosthetics. This amounts to about 2 million patients affected a year. The reason for such statistics is the growth of microorganisms on the surfaces of the medical devices. There have been many attempts to create antimicrobial materials but most materials are unable to hold more than one antimicrobial agent without a secondary process. The study related to antimicrobial material with more than one type of agent is rarely found in literature. Hence, the objective of this project is to produce an antimicrobial material that can hold more than one antimicrobial agent without the need for a secondary process. The material is produced by sulfonating high impact polystyrene (HIPS) and attaching copper and silver ions. The optimum time of sulfonation of the HIPS was determined by the degree of sulfonation and ion exchange capacity. Then, the sulfonated HIPS were loaded with both copper and silver ions at different ratios. The 6-hour sample yielded the highest degree of sulfonation and ionic exchange capacity of 33.7% and 2.57 meq/g, respectively. In future work, the characterization of the 6-hour sulfonated HIPS sample loaded with copper and silver ions at different concentration ratios will be performed using TGA, DSC and FTIR spectroscopy. Lastly, the efficacy of the antimicrobial properties of the sulfonated HIPS will be tested using different bacterial strains.

scholarly journals Rheological and Antimicrobial Properties of Chitosan and Quinoa Protein Filmogenic Suspensions with Thyme and Rosemary Essential Oils

Foods ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 1616
Author(s):  
Monserrat Escamilla-García ◽  
Raquel A. Ríos-Romo ◽  
Armando Melgarejo-Mancilla ◽  
Mayra Díaz-Ramírez ◽  
Hilda M. Hernández-Hernández ◽  
...  
Keyword(s):  
Essential Oils ◽  
Food Packaging ◽  
Antimicrobial Agents ◽  
Negative Impact ◽  
Micrococcus Luteus ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
Rheological Parameters ◽  
Force Microscopy ◽  
Synthetic Materials

Food packaging faces the negative impact of synthetic materials on the environment, and edible coatings offer one alternative from filmogenic suspensions (FS). In this work, an active edible FS based on chitosan (C) and quinoa protein (QP) cross-linked with transglutaminase was produced. Thyme (T) and rosemary (R) essential oils (EOs) were incorporated as antimicrobial agents. Particle size, Z potential, and rheological parameters were evaluated. The antimicrobial activity against Micrococcus luteus (NCIB 8166) and Salmonella sp. (Lignieres 1900) was monitored using atomic force microscopy and image analysis. Results indicate that EOs incorporation into C:QP suspensions did not affect the Z potential, ranging from −46.69 ± 3.19 mV to −46.21 ± 3.83 mV. However, the polydispersity index increased from 0.51 ± 0.07 to 0.80 ± 0.04 in suspensions with EO. The minimum inhibitory concentration of active suspensions against Salmonella sp. was 0.5% (v/v) for thyme and 1% (v/v) for rosemary. Entropy and fractal dimension of the images were used to confirm the antimicrobial effect of EOs, which modified the surface roughness.

scholarly journals Preliminary phytochemical analysis and antibacterial study of crude extract from Hamelia patens stems

2020 ◽  
Vol 4 (02) ◽  
pp. 1-5
Author(s):  
V. Kanchana ◽  
G. Venkat Kumar ◽  
R. V. Shalini
Keyword(s):  
Antimicrobial Activity ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Positive Control ◽  
Diffusion Method ◽  
Phytochemical Analysis ◽  
Antibacterial Study ◽  
Tropical Plant ◽  
Zones Of Inhibition ◽  
Agar Well Diffusion Method

The present study aimed to analyse the phytochemical and antibacterial activity of different extracts of the tropical plant Hamelia patens Jacq. (Rubiaceae). The antimicrobial activity was carried out using agar well diffusion method. Hexane, petroleum ether, ethanol and chloroform stem extracts (100 μL of 50 mg/mL each) were introduced into the wells separately and allowed it to undergo incubation. After the incubation time was over, the plates were observed for zones of inhibition and compared with positive control ciprofloxacin at a concentration of 30 μM. These results provided evidence that the tested plant extracts possess antimicrobial properties which can be tested further in the development of novel antimicrobial agents.

scholarly journals ANTIMICROBIAL ACTIVITIES OF SUCCESSIVE SOLVENT EXTRACTS OF ALBIZIA LEBBECK AND SOLANUM SEAFORTHIANUM AGAINST SOME HUMAN PATHOGENIC MICROORGANISMS

2019 ◽  
pp. 294-296
Author(s):  
HOSUR NARAYANAPPA VENKATESH ◽  
DEVIHALLI CHIKKAIAH MOHANA
Keyword(s):  
Antimicrobial Activity ◽  
Pathogenic Bacteria ◽  
Antimicrobial Agents ◽  
Negative Impact ◽  
Antimicrobial Activities ◽  
Diffusion Method ◽  
Albizia Lebbeck ◽  
Minimal Inhibitory Concentrations ◽  
Broth Dilution

Objective: The continuous emergence of multidrug resistance bacteria and yeast, and the negative impact of synthetic preservatives have led to an increased interest in the use of plant extracts as alternative antimicrobial agents. In the present investigation, the antimicrobial activity of successive solvent extracts of Albizia lebbeck and Solanum seaforthianum has been evaluated against human pathogenic bacteria and yeast. Methods: The disc diffusion method was employed for determination of the zone of inhibitions (ZOIs) and twofold broth dilution technique was employed for determination of minimal inhibitory concentrations, and minimal bactericidal/fungicidal concentrations. Results: Among the successive solvent extracts tested, methanol extracts of both A. lebbeck and S. seaforthianum showed highest antibacterial activity with ZOIs ranged between 10.0 and 20.4 mm at 1 mg/disc followed by ethanol (ZOIs 8.1–17.6 mm). The petroleum ether, toluene, and chloroform extracts showed the least activity. The highest activity was observed against Streptococcus faecalis, whereas the least activity was observed against Pseudomonas aeruginosa. Conclusion: The broad-spectrum antimicrobial activity of methanol extract of A. lebbeck and S. seaforthianum could be explored as antimicrobial agents for the management of pathogenic bacteria and yeast.

scholarly journals UNPRECEDENTED ANTIMICROBIAL PROPERTIES OF PROSOPIS CINERARIA LEAVES

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Dr. Vibha Bhardwaj
Keyword(s):  
Antibacterial Activity ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Multidrug Resistant ◽  
Diffusion Method ◽  
Prosopis Cineraria ◽  
E Coli ◽  
Potential Source ◽  
Wide Range ◽  
Bacillus Subtilis Atcc

The antibacterial effect of Prosopis cineraria leaves was evaluated on multidrug resistant (MDR) strains of Bacillus subtilis (ATCC 6633), E. coli (ATCC 8739), Salmonella enterica (ATCC 14028), Staphylococcus aureus (ATCC 6538), Pseudomonas aeruginosa (ATCC 27853). Powdered leaves of the tree were treated with methanol for the extraction. Crude methanol extracts of the leaves of P. cineraria was investigated for their antibacterial activity against a wide range of bacteria (both gram-positive and gram-negative) by agar well diffusion method. Ciprofloxacin was used as standard. The methanolic leaves extracts of P. cineraria showed a remarkable inhibition of the microorganisms. The potency shown by these extracts recommends their use against multidrug resistant microorganisms. The present study suggests that the methanol extract of the leaves of P. cineraria exhibited a potential antibacterial activity against the tested microorganisms and could be a potential source of new antimicrobial agents.

scholarly journals ANTIMICROBIAL PROPERTIES OF LEPTADENIA HASTATA (PERS) DECNE LEAVES EXTRACT

2018 ◽  
Vol 10 (2) ◽  
pp. 149 ◽  
Author(s):  
Isaac John Umaru ◽  
Fasihuddin A. Badruddin ◽  
Zaini B. Assim ◽  
Hauwa A. Umaru
Keyword(s):  
Ethyl Acetate ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Salmonella Typhi ◽  
New Drugs ◽  
Diffusion Method ◽  
Zone Of Inhibition ◽  
Medical Practitioners ◽  
Antibacterial Potential ◽  
Agar Well Diffusion Method

Objective: This study was carried out with an objective to investigate the antibacterial potential of five leaf extract of Leptadenia hastata plant on some bacteria.Methods: Leptadenia hastata extracts were evaluated for potential antimicrobial properties. The leaves of the plant were extracted with n-hexane, dichloromethane, ethyl acetate, chloroform and methanol and then vaporized to give respective extracts. Antimicrobial activity against Escherichia coli, salmonella typhi, staphylococcus aureus and Klebsielia pneumonia, was determined by an agar well diffusion method. The optical density of the broth using UV mini spectrophotometer and zone of inhibition by the crude extract were determined.Results: The results showed that of n-hexane, ethyl acetate, dichloromethane and methanol extracts of Leptadenia hastata, methanolic and chloroform extracts displayed more activity with 1.10±0.10 mmab and 0.97±0.06 mmab where aSignificantly (p<0.05) higher compared to different extract at the same concentration bSignificantly (p<0.05) lower compared to the control, than others at 25-1000 ppm per well of the extracts tested.Conclusion: The present results showed the potential of the medicinal plant used by traditional herbal medical practitioners as natural antimicrobial agents, thus can be further used to determine the bioactive products that may provide as leads in the development of new drugs.

Dicentra scandens (D.Don) Walp. - A Potential Source of Antimicrobial Agent

2017 ◽  
Vol 9 (01) ◽  
Author(s):  
Koirala Pramila ◽  
Singh Bimala
Keyword(s):  
Antimicrobial Activity ◽  
Antimicrobial Agent ◽  
Methanol Extract ◽  
Shigella Flexneri ◽  
Antimicrobial Properties ◽  
Salmonella Typhi ◽  
Gas Chromatography Mass Spectrometry ◽  
Diffusion Method ◽  
Methanol Extracts ◽  
Ms Analysis

Dicentra scandens (D.Don) Walp. locally called as ‘Jogi Lahara’ belongs to the Family Fumariaceae and is used in traditional medicine in Sikkim, a North Eastern state of India. The present study investigated the antimicrobial properties of aqueous and methanol extracts of Dicentra scandens (D.Don) Walp. against some test Gram negative and Gram positive bacteria. Using agar well diffusion method, aqueous and methanol extracts of roots of Dicentra scandens were tested against Escherichia coli (MTCC 1089), Klebsiella pneumoniae (MTCC 3384), Pseudomonas aeruginosa (MTCC 1034), Proteus vulgaris (MTCC 742), Salmonella typhi (MTCC 733), Shigella flexneri (MTCC 1457), Vibrio cholerae O139(MTCC 3906), Bacillus cereus (MTCC 6840) and Staphylococcus aureus (MTCC 7443). Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were also evaluated. Promising antimicrobial activity was exhibited by methanol extract of Dicentra scandens. The methanol extract was further characterized by Gas Chromatography-Mass Spectrometry (GC-MS) analysis. The GC-MS analysis revealed 29 compounds and the major compounds detected were Protopine (53.78%) and Corydine (18.20%). Thus, the alkaloids are predominant phytoconstituents of the extract and could be attributed to its antimicrobial activity. The results of the present study indicate that, Dicentra scandens can be a source of potential antimicrobial agent and can be explored further for its therapeutic use.

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