scholarly journals Retraction: Calvo-Guirado, J.L., et al. Experimental Study on the Influence of Apigenin K and Melatonin in Socket Preservation as Bone Stimulators: An Experimental Study in Beagle Dogs. Appl. Sci. 2020, 10, 3006

2020 ◽  
Vol 10 (17) ◽  
pp. 5865
Author(s):  
Keyword(s):  
Experimental Study ◽  
Beagle Dogs ◽  
Socket Preservation ◽  
Published Paper

In the published paper [...]

scholarly journals Experimental Study on the Influence of Apigenin K and Melatonin in Socket Preservation as Bone Stimulators: An Experimental Study in Beagle Dogs

2020 ◽  
Vol 10 (9) ◽  
pp. 3006 ◽  
Author(s):  
José Luis Calvo-Guirado ◽  
Manuel Fernández-Domínguez ◽  
Juan Manuel Aragoneses ◽  
Enrique Fernández-Bodereau ◽  
Miguel Angel Garcés-Villalá ◽  
...  
Keyword(s):  
Experimental Study ◽  
Topical Application ◽  
Bone Matrix ◽  
Control Group ◽  
Beagle Dogs ◽  
Socket Preservation ◽  
Size Dependent ◽  
The Third ◽  
The Creation ◽  
And Control

The aim is to evaluate whether apigenin K and melatonin M5250 were able to stimulate bone formation after tooth extraction at one, two, and three months follow-up. Six male beagle dogs were used. Apigenin K and melatonin M5250 immersed in hemostatic collagen sponges were placed in the third and fourth premolar and the first molar extracted sockets; the second premolar was used as control. At one, two, and three months, bone core biopsies were performed, and picrosirius–hematoxylin was used for the staining process. In the first month, a higher amount of calcified bone tissue was observed in the melatonin (77.87% ± 1.2%) and apigenin K (69.81% ± 1.8%) groups than the control group (57.27% ± 0.54%), with apparent discrepancies in values between the three groups (p < 0.04). In the second month, there was a considerable improvement in the results in the areas with melatonin (79.81% ± 0.11%) than in those of apigenin K (71.65% ± 0.52%) and control (64.77% ± 0.44%) (p < 0.04). In the third month, the number of mature bone was similar to all the groups. The creation of new bone was significant in the melatonin group (82.78% ± 0.87%), followed by the apigenin K group (78.76% ± 0.43%) and the control group (57.27% ± 0.11%). From this experimental study in dogs, it can be concluded that melatonin and apigenin K can accelerate the process of mineralization of the bone matrix, and thus the creation of laminae in the early stages of healing (1 month). Less reabsorption of the post-extraction sockets can be expected with the topical application of melatonin and apigenin K. It seems that the stimulatory effects of bone healing induced by the topical application of melatonin and apigenin K are defect-size-dependent, being more evident in small defects compared to larger defects.

scholarly journals Soft tissue healing of immediate and delayed implants. An experimental study in beagle dogs.

2018 ◽  
Vol 29 ◽  
pp. 47-47
Author(s):  
David Palombo ◽  
Fabio Vignoletti ◽  
Javier Sanz-Esporrín ◽  
Javier Nuñez ◽  
Mariano Sanz
Keyword(s):  
Experimental Study ◽  
Soft Tissue ◽  
Beagle Dogs ◽  
Soft Tissue Healing ◽  
Tissue Healing

scholarly journals Section Plane Effects on Morphometric Values of Microcomputed Tomography

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Young-Seok Park
Keyword(s):  
Microcomputed Tomography ◽  
Section Plane ◽  
Two Dimensional ◽  
Trial And Error ◽  
Beagle Dogs ◽  
Concordance Correlation ◽  
Socket Preservation ◽  
3 Dimensional ◽  
Parallel Movement ◽  
Preservation Technique

Objectives. Histomorphometry is the established gold standard for inspection of trabecular microstructures in biomaterial research. However, microcomputed tomography can provide images from the perspective of various section planes. The aim of the present study was to evaluate the effects of different section planes, which may cause bias in two-dimensional morphometry, on the morphometric values of microcomputed tomography. Methods. A socket preservation technique was performed on the extracted premolar area of 4 beagle dogs. After an 8-week healing period, a total of 16 specimens were obtained and analyzed with conventional histomorphometry and microtomographic morphometry. Using the original images of the histologic specimens for comparison, the most similar tomographic image was selected by trial and error. Then, the section plane was then moved with ±79 μm parallel offsets and rotated ±10° around the center from the occlusal view. The images were compared in terms of bone, graft, and noncalcified area, and the concordance correlation coefficient (CCC) was calculated. Results. There was a high CCC in the comparison between histomorphometric images and the most similar microtomographic images. However, the CCC value was low in the comparisons with both parallel movement and rotation. Our results demonstrate that the sectioning plane has a significant effect on measurements. Conclusion. Two-dimensional morphometric values for biomaterial research should be interpreted with caution, and the simultaneous use of complementary 3-dimensional tools is recommended.

Enamel matrix derivative in liquid form as adjunct to natural bovine bone grafting at buccal bone dehiscence defects at implant sites: An experimental study in beagle dogs

2019 ◽  
Vol 30 (10) ◽  
pp. 989-996 ◽  
Author(s):  
Takahiro Ikawa ◽  
Tatsuya Akizuki ◽  
Ammar Shujaa Addin ◽  
Shunsuke Fukuba ◽  
Andreas Stavropoulos ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Grafting ◽  
Enamel Matrix Derivative ◽  
Bovine Bone ◽  
Enamel Matrix ◽  
Beagle Dogs ◽  
Liquid Form ◽  
Matrix Derivative

scholarly journals A Novel HA/β-TCP-Collagen Composite Enhanced New Bone Formation for Dental Extraction Socket Preservation in Beagle Dogs

Materials ◽  
2016 ◽  
Vol 9 (3) ◽  
pp. 191 ◽  
Author(s):  
Ko-Ning Ho ◽  
Eisner Salamanca ◽  
Kuo-Chi Chang ◽  
Tsai-Chin Shih ◽  
Yu-Chi Chang ◽  
...  
Keyword(s):  
Bone Formation ◽  
Dental Extraction ◽  
New Bone Formation ◽  
Beagle Dogs ◽  
Extraction Socket ◽  
Socket Preservation

Narrow- versus mini-implants at crestal and subcrestal bone levels. Experimental study in beagle dogs at three months

2014 ◽  
Vol 19 (6) ◽  
pp. 1363-1369 ◽  
Author(s):  
José Luis Calvo-Guirado ◽  
Carlos Pérez-Albacete ◽  
Antonio Aguilar-Salvatierra ◽  
José E. de Val Maté-Sánchez ◽  
Rafael A. Delgado-Ruiz ◽  
...  
Keyword(s):  
Experimental Study ◽  
Beagle Dogs ◽  
Mini Implants

scholarly journals Experimental study on anaphylaxis of Qingkailing injection and its components on Beagle dogs

2012 ◽  
Vol 32 (4) ◽  
pp. 641-645 ◽  
Author(s):  
Zhiguo Wang ◽  
Danqiao Wang ◽  
Yu Sui ◽  
Haifeng Cui ◽  
Youhua Yu
Keyword(s):  
Experimental Study ◽  
Beagle Dogs ◽  
Qingkailing Injection

Heparin Catabolism Under Extracorporeal Circulation in Cardiac Surgery: Experimental Study

1979 ◽  
Author(s):  
M. Simonuff ◽  
Ch. Doutremepuich ◽  
A. Chauve ◽  
J. Nicod ◽  
F. Fontan
Keyword(s):  
Experimental Study ◽  
Cardiac Surgery ◽  
Extracorporeal Circulation ◽  
Gastric Fluid ◽  
Beagle Dogs ◽  
C 30

Extracorporeal circulation E. C. C. was performed on 13 Beagle dogs to deter mine heparin catabolism. Three types of heparin were used: a cold heparin and two radio-active(R. A.) heparins (S-35 and H-3) The E.C.C. was performed for 70 minutes (mn.) in all dogs, at a temperature of 37°C. in 4 dogs, 28°C in 4 and 20°C. in 5, (duration of hypothermia: 30 mn.).1) Plasmatic heparin elimination was related to the E. C. C. temperature: 42.6% at 37°C., 30 7% at 28 ° C. and 14.6% at 20°C. The biological half-lives were respectively 60 + 10 mn, 80 + 10 mn, and 200 + 20 mn.2) Urinary heparin elimination was delayed with respect to the E. C. C. temperature and independant of the type of heparin used. At the same time, the relation of heparin in plasmatic R.A, to urinary R.A. was constant(≈ 10) during the entire E. C. C.3) The study of the gastric fluid in 8 dogs showed an heparin elimination increased to a maximum at the end of the E.C.C.; at that time, the plasmatic R. A. to gastric R.A.heparin relation, in 5 dogs, was equal to 1.The study indicates that a)there is a correlation between the dosage made, try classical and radta-active melhods, b) the lowering of E. C. C. temperature diminfshes the catabolism of heparin, and c) a gastric heparin elimination during E. C. C.

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