scholarly journals Experimental Study on the Influence of Apigenin K and Melatonin in Socket Preservation as Bone Stimulators: An Experimental Study in Beagle Dogs

2020 ◽  
Vol 10 (9) ◽  
pp. 3006 ◽  
Author(s):  
José Luis Calvo-Guirado ◽  
Manuel Fernández-Domínguez ◽  
Juan Manuel Aragoneses ◽  
Enrique Fernández-Bodereau ◽  
Miguel Angel Garcés-Villalá ◽  
...  
Keyword(s):  
Experimental Study ◽  
Topical Application ◽  
Bone Matrix ◽  
Control Group ◽  
Beagle Dogs ◽  
Socket Preservation ◽  
Size Dependent ◽  
The Third ◽  
The Creation ◽  
And Control

The aim is to evaluate whether apigenin K and melatonin M5250 were able to stimulate bone formation after tooth extraction at one, two, and three months follow-up. Six male beagle dogs were used. Apigenin K and melatonin M5250 immersed in hemostatic collagen sponges were placed in the third and fourth premolar and the first molar extracted sockets; the second premolar was used as control. At one, two, and three months, bone core biopsies were performed, and picrosirius–hematoxylin was used for the staining process. In the first month, a higher amount of calcified bone tissue was observed in the melatonin (77.87% ± 1.2%) and apigenin K (69.81% ± 1.8%) groups than the control group (57.27% ± 0.54%), with apparent discrepancies in values between the three groups (p < 0.04). In the second month, there was a considerable improvement in the results in the areas with melatonin (79.81% ± 0.11%) than in those of apigenin K (71.65% ± 0.52%) and control (64.77% ± 0.44%) (p < 0.04). In the third month, the number of mature bone was similar to all the groups. The creation of new bone was significant in the melatonin group (82.78% ± 0.87%), followed by the apigenin K group (78.76% ± 0.43%) and the control group (57.27% ± 0.11%). From this experimental study in dogs, it can be concluded that melatonin and apigenin K can accelerate the process of mineralization of the bone matrix, and thus the creation of laminae in the early stages of healing (1 month). Less reabsorption of the post-extraction sockets can be expected with the topical application of melatonin and apigenin K. It seems that the stimulatory effects of bone healing induced by the topical application of melatonin and apigenin K are defect-size-dependent, being more evident in small defects compared to larger defects.

THE EFFECT OF APPLYING DEMONSTRATION METHOD ON STUDENTS’ ACHIEVEMENT IN SPEAKING SKILL AT THE THIRD GRADE OF SMK PAB 3 MEDAN ESTATE

2015 ◽  
Vol 4 (2) ◽  
Author(s):  
Meryanti Napitupulu And Anni Holila Pulungan
Keyword(s):  
High School ◽  
Control Group ◽  
Vocational High School ◽  
Control Groups ◽  
Speaking Test ◽  
The Third ◽  
Speaking Skill ◽  
The Subject ◽  
And Control ◽  
Experimental Group

This study was conducted as an attempt to discover the effect of applying Demonstration Method on students’ achievement in speaking skill. It was an experimental research. The subject was students of Grade XII, Vocational High School (Sekolah Menengah Kejuruan: SMK), which consisted of 79 students. The research was divided into two groups: experimental and control groups. The instrument used to collect the data was speaking test. To obtain the reliability of the test, the writer applied Kuder Richardson 21 formula. The result of the reliability was 0.7, and it was found that the test was reliable. The data were analyzed by using t-test formula. The analysis showed that the scores of the students in the experimental group were significantly higher than the scores of the students in the control group at the level of significant m = 0.05 with the degree of freedom (df) 77, t-observed value 8.9 > t-table value 1.99. The findings indicate that using Demonstration Method significantly affected the students’ achievement in speaking skill. So, English teachers are suggested to use Demonstration Method in order to improve students’ achievement in speaking skill.

scholarly journals THE EFFECT OF DEFINITIONS TOWARD STUDENTS’ VOCABULARY

2018 ◽  
Vol 6 (1) ◽  
pp. 34
Author(s):  
Tawali Tawali
Keyword(s):  
Experimental Study ◽  
Alternative Hypothesis ◽  
T Test ◽  
Second Grade ◽  
Control Group ◽  
Second Grade Students ◽  
Post Test ◽  
The Subject ◽  
And Control ◽  
Experimental Group

This research is aimed to find out the effect of definitions toward students’ vocabulary mastery: it was an experimental study at the second grade student of MTs NW Haqqul Yaqin Sayang- sayang. The subject of this research was the second grade of MTs NW Haqqul Yaqin Sayang- sayang.The research was used experimental method with quantitative approach. The population of this research consist of 55 students, and the sample is 29 for experimental group while 26 for control group. The technique of collecting data was used definition for experimental group and matching word with antonym for control group. The data was collected by using post-test only and the data was analyzed by t-test formula. Based on data analysis the mean score of experimental group was 76,4 and control group was 69,23, beside of that standard deviation for experimental group was 114,28 and for control group was 113,09 and the value of t-test was 2,44 and t-table was 2,000. Degree of freedom is 53 with significant level 0,05. It means that the value of t-test was higher than t-table (t-test ˃ t-table). The alternative hypothesis (Ha) was accepted and null hypothesis (Ho) was rejected. Thus, the conclusion of this research was there was an effect of definition toward students’ vocabulary mastery: an experimental study at the second grade students of MTs NW Haqqul Yaqin Sayang-sayang.

scholarly journals A STUDY OF THE EFFECT OF THE PHYTOCHEMICAL CONTENT OF P. AMERICANALEAF ON HEMATOLOGICAL SYSTEM OF ALBINO RATS

2021 ◽  
Vol 9 (04) ◽  
pp. 464-467
Author(s):  
Ngozi a ◽  
◽  
N. Omeke ◽  
Haruna M. Ndahi ◽  
◽  
...  
Keyword(s):  
Adverse Effect ◽  
Experimental Study ◽  
Aqueous Extract ◽  
Leaf Extract ◽  
Control Group ◽  
Albino Rats ◽  
Phytochemical Content ◽  
Other Substances ◽  
And Control ◽  
Experimental Group

Given the medicinal importance of the avocado plant in alternative medicine,the present study aimed to study the effect of the phytochemical content of P. americana leaf extract on the hematological system of albino rats. Albino rats were obtained andclustered into sixgroups,with five rats per groupsimultaneously were assigned experimental and control. The rats in the experimental group were administered with varying doses of the prepared aqueous extract of P. americanawithin the period of the study. The rats in the control group were administered with other substances such as water and feed for the study period.The hematological system of the experimental animal was assessed after the administration of the extract, and it was observed that the aqueous extract of P. americana leaf recorded no significant adverse effect on the hematology system of the experimental study animal.

scholarly journals EFFECT OF PREGNANCY EXERCISE ON DURATION OF THE FIRST AND SECOND STAGE OF LABOR IN PRIMIGRAVIDA MOTHERS DURING THE THIRD TRIMESTER OF PREGNANCY

2017 ◽  
Vol 3 (6) ◽  
pp. 765-770
Author(s):  
Iin Wahyuni ◽  
Noor Pramono ◽  
Titi Suherni ◽  
Melyana Nurul Widyawati
Keyword(s):  
Community Health ◽  
Health Center ◽  
Average Duration ◽  
Community Health Center ◽  
Control Group ◽  
Third Trimester ◽  
Second Stage Of Labor ◽  
Second Stage ◽  
The Third ◽  
And Control

Objective: This study aimed to examine the pregnancy exercise during the third trimester of pregnancy on duration of the first and second stage of labor in primigravida at the Community Health Center of Sukamaju, Bandar lampung, Indonesia.Methods: This study employed a quasy experimental design with posttest-only non-equivalent control group. This study was conducted from 8 January 2017 to 12 February 2017 at the Community Health Center of Sukamaju. Forty-eight primigravida mothers were selected using consecutive sampling, with 24 assigned in the experiment and control group. Data were analyzed using Mann whitney and Chi square test.Results: The average duration of the first stage of labor in the experiment group was 495 minutes and in the control group was 685 minutes (p= 0.000); while the average duration of the second stage of labor in the experiment group was 42.5 minutes and in the control group was 68.75 minutes (p=0.000).Conclusion: There was a statistically significant difference in the duration of the first and second stage of labor between experiment and control group. It is expected for midwives in the community health centers to implement pregnancy exercise program to help mothers in accelerating the delivery process.

scholarly journals Effect of pesticide Glyphosate Aqua in liver enzymes activity of Barbus sharpeyi

2016 ◽  
Vol 13 (2) ◽  
pp. 240-246
Author(s):  
Baghdad Science Journal
Keyword(s):  
Liver Enzymes ◽  
Fish Nutrition ◽  
Control Group ◽  
Average Weight ◽  
Biochemical Tests ◽  
The Third ◽  
Nutrition Research ◽  
Barbus Sharpeyi ◽  
Activity Of Enzymes ◽  
And Control

The present study was designed in the aquaculture and fish nutrition research aquarium in the College of Veterinary Medicine/Baghdad University from a period 1/3 to 1/6/2013 to investigate the toxicity of the herbicide glyphosate aqua on Barbus sharpeyi fish. Fish fingerlings were used with average weight between 10 – 15 gm to measure the (LC50), and 200 fingerlings were used to know the acute and chronic toxic effect for the herbicide. The fingerlings were randomly distributed as 10 fish for each aquarium. Fish were divided into four treatments and control group (without addition of herbicide). The first processing with a concentration of 0.415 mg/L for a duration of exposure 90 days, the second processing group with a concentration 0.415 mg/L for 15 days, while the third group was treated with 0.207 mg/L of the herbicide for a duration of exposure, the forth group was exposed to 0.207 mg/L for 15 days only. The study aimed to determine the extent of the effect of the pesticide in the activity of liver enzymes, which included Alkaline phosphatase (ALP), Aspartate amino transfers (AST) and Alanine amino transfers (ALT). The results of biochemical tests for liver enzymes to fish experience has shown a rise in activity of enzymes which increased with duration of exposure. The first and the third treatments has a significant differences (P ?0.05) compared with control group. Results of the experiment to improvement in the health status of fish in second and forth treatments compared to control group.

Mammary Tumors in a Colony of Beagle Dogs

1986 ◽  
Vol 23 (6) ◽  
pp. 741-749 ◽  
Author(s):  
J. E. Moulton ◽  
L. S. Rosenblatt ◽  
M. Goldman
Keyword(s):  
Morphological Type ◽  
Control Group ◽  
Beagle Dogs ◽  
Control Groups ◽  
First Occurrence ◽  
Closed Colony ◽  
Benign Mixed Tumor ◽  
Age Range ◽  
And Control ◽  
Mixed Tumors

In a lifetime study, female beagle dogs in a closed colony were administered 226radium and 90strontium. An unirradiated control group was included in the study. A total of 223 of 356 dogs at risk developed 1,112 mammary proliferative growths (hyperplastic nodules and neoplasms). There was no correlation between occurrence and types of lesions in radiation and control groups. The age range for first occurrence of lesions was 10.4 to 13.9 years; hyperplastic nodule and benign mixed tumor occurred 1 to 2 years earlier than other lesions. A multiplicity of growths of similar or different morphological type were common throughout the lifetime of the dog. The female beagles, collectively, developed 244 hyperplastic nodules, 78 adenomas, 694 benign mixed tumors, 78 carcinomas, 14 malignant mixed tumors, and four myoepitheliomas. Proliferations occurred with increasing frequency from the cranial to caudal mammary glands. Metastasis was found in 77% of the dogs with carcinoma. The median time from diagnosis to metastasis was 10 months, but was shorter in dogs with infiltrative carcinoma.

Dexamethasone attenuates reversal of hypertension in one-kidney, one-clip rats

1988 ◽  
Vol 255 (4) ◽  
pp. H717-H721
Author(s):  
H. M. McGowan ◽  
R. Vandongen ◽  
B. Smith
Keyword(s):  
Phospholipase A2 ◽  
Treated Group ◽  
Control Group ◽  
Sprague Dawley ◽  
Hypertensive Rats ◽  
The Third ◽  
Serum Thromboxane ◽  
And Control ◽  
Oral Doses ◽  
Prostanoid Synthesis

This study examines the effect of dexamethasone (Dex), a phospholipase A2 inhibitor, on the reversal of 1-kidney, 1-clip (1K,1C) hypertension and the synthesis of phospholipase A2-dependent products. Male Sprague-Dawley 1K,1C hypertensive rats [blood pressure (BP) greater than 190 mmHg] were allocated to three groups: two groups were given daily oral doses of Dex (0.142 mg/kg in water) for 72 h, whereas the third group was given water only (controls). One of the Dex-treated groups was then sham unclipped (n = 9), while the other Dex-treated group (n = 8) and the control group (n = 8) were unclipped. Dex attenuated the BP fall in the unclipped (223 +/- 8-148 +/- 9 mmHg) compared with the control unclipped (226 +/- 9-114 +/- 5 mmHg) animals (P less than 0.005). Aortic 6-ketoprostaglandin F1 alpha (6-keto-PGF1 alpha) was reduced in unclipped Dex-treated rats (13.4 +/- 1.2 ng/mg) compared with unclipped control rats (16.3 +/- 1.4 ng/mg; P less than 0.05) but was higher than in the sham-unclipped Dex group (11.5 +/- 1.2 ng/mg; P less than 0.05). Serum thromboxane B2 (TxB2) in the unclipped Dex-treated group was lower than in the unclipped control rats (P less than 0.05) but higher than in sham-unclipped rats (P less than 0.05). Dex significantly increased urinary prostaglandin E2 (PGE2) excretion, whereas urinary 6-keto-PGF1 alpha was unaltered. After unclipping, both urinary PGE2 and 6-keto-PGF1 alpha increased significantly, although there was no obvious difference between Dex-treated and control animals. These findings demonstrate opposite effects of Dex on renal compared with extrarenal prostanoid synthesis and support the hypothesis that attenuation of aortic 6-keto-PGF1 alpha synthesis may be responsible for the smaller fall in BP after unclipping in Dex-treated rats.

P054 The impact of intestinal stenosis on the expression of Crohn’s disease in young mice with genetic predisposition

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S161-S161
Author(s):  
I Georgopoulos ◽  
E Mavrigiannaki ◽  
S Stasinopoulou ◽  
G Renieris ◽  
G NIkolakis ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Terminal Ileum ◽  
Suture Technique ◽  
Intraluminal Pressure ◽  
Control Group ◽  
Intestinal Stenosis ◽  
The Creation ◽  
And Control ◽  
The Impact

Abstract Background In the majority of patients, the areas of the intestine affected in Crohn’s disease (CD) are the terminal ileum and less commonly the rectum. The terminal ileum is affected in the majority of genetic animal models of CD as well. Additionally, CD recurs at sites of tight anastomosis or strictures postoperatively. These observations lead to the assumption that increased intraluminal pressure related to the presence of a valve, sphincter or stenosis is associated with CD pathogenesis. We investigated the hypothesis that the creation of a partial intestinal stenosis could have an impact on disease severity, in a genetic animal model of CD (TNFΔare/+). TNFΔare/+ mice overexpress TNFα leading to a Crohn-like colitis in the terminal ileum. Methods Twenty-nine TNFΔare/+ mice, 6 weeks old, were divided into three intervention groups: stenosis, sham and control. In the stenosis group (n = 11), a partial small bowel obstruction was created via a novel triple suture technique, approximately 3 cm from the ileocecal valve. In the control group (n = 9), a loose single suture was placed at the aforementioned site to test the direct effect of the foreign material on the intestinal wall. The sham group (n = 9) received a sham operation. The triple suture stenosis was also performed on wild-type (WT) C57BL/6 mice (group WT, n = 9). 6 weeks post-surgery all animals were sacrificed and samples from the ileum 3 cm proximal and 3 cm distal to the intervention site were collected for histopathological evaluation. The Crohn-like changes were assessed using a modified colitis histological scoring system (based on Katakura et al., JCI 2005; 115: 695–702). Results Proximal to the intervention, the mean colitis score of stenosis group (10.18 ± 0.87) was significantly higher compared with sham (6.33 ± 0.97, p: 0.009) and control group (5.00 ± 0.91, p: 0.001). There was no difference between sham and control group (p: 0.332). No significant differences between the groups were reported distal to the intervention. The triple suture technique led to Crohn-like inflammatory lesions only in the TNFΔare/+ mice, as shown from the significantly increased score compared with WT mice proximal and distal to the stenosis (10.18 ± 0.87 vs. 0.67 ± 0.37, p &lt; 0.001 and 9.20 ± 1.09 vs. 0.33 ± 0.24, p &lt; 0.001). Conclusion The creation of a stenotic segment in the intestine of TNFΔare/+ mice, led to higher colitis score than expected. The probable mechanism is the increased intraluminal pressure proximal to the stenosis. This suggests that mechanical forces contribute as important co-factors in the pathophysiology of CD, in genetically predisposed populations.

scholarly journals Training interventions on Helping Babies Breathe among health workers in tertiary hospital of the Republic of South Sudan: A non-randomized quasi-experimental study

2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Christopher Vunni Draiko ◽  
Khemika Yamarat ◽  
Alessio Panza ◽  
Judith Draleru ◽  
Martin Taban ◽  
...  
Keyword(s):  
Experimental Study ◽  
Health Workers ◽  
South Sudan ◽  
Intervention Group ◽  
Control Group ◽  
Training Interventions ◽  
Helping Babies Breathe ◽  
Newborn Mortality ◽  
Quasi Experimental ◽  
And Control

This study aimed to examine the effects of the Helping Babies Breathe (HBB) training interventions program on the knowledge, psychomotor skills, and competency of health workers in managing birth asphyxia and reducing mortality of newborns experiencing asphyxia within 24 hours. This study used pre- and post-test design (quasi experimental study). Purposive sampling was employed, and a computer-generated number was used to select the participants. Health workers from Juba Teaching Hospital comprised the intervention group. They were evaluated before and after the training from February to June 2017. A post training skill and competency evaluation was performed using a NeoNatalie newborn simulator and was repeated after three months of implementation for intervention and control group. Seventy health workers were enrolled; 40 were in the intervention group and 30 in the control group. Early newborn mortality due to asphyxia within 24 hours in intervention and control measure at pre and post implementation showed a significant reduction within the intervention than the control. Knowledge, psychomotor and competency of health care workers improved immediately after training and early newborn mortality reduced by half at the end of three months. It is recommended that training of health workers on HBB should be scaled up in most of the health facilities in South Sudan.

scholarly journals Effect of paiteling on the alteration of persistent HR-HPV infection after panhysterectomy

2018 ◽  
Vol 16 ◽  
pp. 205873921881917
Author(s):  
Ye Zhao ◽  
Qiu-Man Wang ◽  
Li-Ting Yao ◽  
Xiao Han
Keyword(s):  
Human Papillomavirus ◽  
Adverse Reactions ◽  
Intraepithelial Neoplasia ◽  
Hpv Infection ◽  
Control Group ◽  
The Third ◽  
Conversion Rates ◽  
The Difference ◽  
And Control ◽  
Negative Conversion

This study aims to determine the effect of paiteling by placing a vaginal stump on the outcome of persistent high-risk human papillomavirus (HR-HPV) infection after hysterectomy for cervical intraepithelial neoplasia (CIN). From January 2013 to December 2015, 125 patients were enrolled in the study. These patients were divided into groups, according to patient’s preference. There were 55 patients in the paiteling group, while there were 70 patients in the control group. At the end of the third and ninth month, Thinprep cytology test (TCT) and human papillomavirus (HPV) typing were reviewed to determine the changes in HR-HPV and its complications. The negative conversion rates of these two groups were observed. Patients in the control group were observed and followed up without treatment. At the third month after treatment, HPV negative rates were 83.64% and 34.29% in the paiteling group and control group, respectively (χ2 = 30.444, P < 0.01). In the ninth month, the rate of HPV negative conversion was 90.91% in the paiteling group and 48.57% in the control group (χ2 = 25.047, P < 0.01). The difference between the two groups was statistically significant, and patients in both groups had no obvious adverse reactions. Paiteling irrigation at the vaginal stump can accelerate the positive-to-negative conversion of HR-HPV infection after panhysterectomy.

Sign in / Sign up

Export Citation Format

Share Document