scholarly journals Graphene–Chitosan Hybrid Dental Implants with Enhanced Antibacterial and Cell-Proliferation Properties

2020 ◽  
Vol 10 (14) ◽  
pp. 4888 ◽  
Author(s):  
Sunho Park ◽  
Hyeran Kim ◽  
Kyoung Soon Choi ◽  
Min-Kyung Ji ◽  
Sujin Kim ◽  
...  
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Cell Activity ◽  
Functional Abilities ◽  
Tooth Replacement ◽  
Oral Rehabilitation ◽  
Natural Teeth ◽  
New Type ◽  
Implant Treatment ◽  
Effective Design

Dental implants are widely used tooth replacement tools owing to their good oral rehabilitation and reconstruction capacities. Since dental implants are designed as a replacement for natural teeth, multi-functional abilities are desired to achieve successful implant treatment with improved osseointegration through promotion of mammalian cell activity and prevention of bacterial cell activity. In this study, we developed a graphene–chitosan hybrid dental implant (GC hybrid implant) using various concentrations of graphene, which demonstrated the different surface properties including increased wettability and roughness. Importantly, the GC hybrid implant under the optimal condition (i.e., 1% GC hybrid implant) could significantly promote osteoblast proliferation while reducing biofilm formation and bacterial activity. Our study demonstrates the potential of using this GC hybrid implant as a new type of dental implant, which can offer an effective design for the fabrication of advanced dental implants.

scholarly journals Statistic study regarding mandibular canal in dentate human specimens

2015 ◽  
Vol 61 (4) ◽  
pp. 300-303
Author(s):  
Victor Nimigean ◽  
◽  
Valentin Daniel Sîrbu ◽  
Vanda Roxana Nimigean ◽  
Lavinia Buţincu ◽  
...  
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Mandibular Canal ◽  
Precise Location ◽  
Oral Rehabilitation ◽  
Statistic Study ◽  
Long Term Performance ◽  
Term Performance ◽  
Implant Treatment

The major risk of dental implant treatment in the mandible is represented by the mandibular canal. Precise location of the mandibular canal is essential for oral rehabilitation with dental implants. The aim of this study was to analyze the topography of the mandibular canal in order to increase the long-term performance of oral rehabilitation with dental implants in „poor areas“. The topography of the mandibular canal was statistically studied on 11 human mandibles. The results obtained show similarities but also differences with data reported in other specialized references.

Development of Antiresorptive Agent-Related Osteonecrosis of the Jaw After Dental Implant Removal: A Case Report

2018 ◽  
Vol 44 (5) ◽  
pp. 359-364
Author(s):  
Shinsuke Yamamoto ◽  
Keigo Maeda ◽  
Izumi Kouchi ◽  
Yuzo Hirai ◽  
Naoki Taniike ◽  
...  
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Osteonecrosis Of The Jaw ◽  
Japanese Woman ◽  
Implant Removal ◽  
Antiresorptive Agent ◽  
Oral Bisphosphonate ◽  
Antiresorptive Agents ◽  
The Right ◽  
Implant Treatment

Dental implant treatment is a highly predictable therapy, but when potentially lethal symptoms or complications occur, dentists must remove the implant fixture. Recently, reports on antiresorptive agent-related osteonecrosis of the jaw have increased in the field of dental implants, although the relationship between dental implant treatment and antiresorptive agents remains unclear. Here, we report a case of antiresorptive agent-related osteonecrosis of the jaw that developed after dental implant removal. A 67-year-old Japanese woman with a medical history of osteoporosis and 7 years of oral bisphosphonate treatment was referred to our hospital with a chief complaint of painful right mandibular bone exposure. A family dentist removed the dental implants from the right mandible using a trephine drill without flap elevation in August 2016. However, the healing was impaired; she was referred to our hospital 3 months after the procedure. We performed a sequestrectomy of the mandible under general anesthesia. In conclusion, this patient's course has two important implications: First, the removal of dental implants from patients who are prescribed oral bisphosphonates for long durations can cause antiresorptive agent-related osteonecrosis of the jaw. Second, meticulous procedures are required to prevent and treat the development of antiresorptive agent-related osteonecrosis of the jaw after dental implant removal.

scholarly journals Oral Rehabilitation on Implants and Introduction of Pathogenic Mechanisms in Relation to Oral Implants - Sugar Diabetes

2019 ◽  
Vol 70 (10) ◽  
pp. 3750-3752
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Failure Rate ◽  
Primary Stability ◽  
Advanced Technology ◽  
Diabetic Patients ◽  
Oral Rehabilitation ◽  
Complete Replacement ◽  
Oral Implants ◽  
Dental Aesthetics

Dental implants are made of medical titanium and perfectly fit into human bone tissue; the dental implant can last a lifetime. Not beeing living organic structures, there are no nerve endings, neither at the implant level nor at the artificial crown level. The use of quality implants by an experienced implantologist, assisted by advanced technology, transforms the treatment with dental implants into the medical-surgical act with the highest success rate among dental and even medical treatments.Through the complete replacement of the tooth, including the root, can artificially reproduce the function of the natural tooth, with a strong and stable base. The implant crown, made of aesthetic materials (porcelain, zirconium) and anchored to it by means of the prosthetic abutment, will be surrounded by a healthy and aesthetic gum. Especially if the prosthetic abutment (the connecting element between the implant itself and the artificial crown) will be made of zirconium - natural light will cross ceramic layers, similar to enamel and dentine, offering a white of envy and glitter to the smile. Around the porcelain crowns (whole ceramics or zirconia ceramics) the gingiva will conform healthily, without the slightest sign of inflammation. These elements, the white of the teeth and the pink of the gums define the concept of dental aesthetics. The main problems that diabetic patients may encounter, are gingival inflammation and periodontal disease, dental mobility and tooth loss. When a dental implant is influenced by the type of diabetes, its failure rate is higher in patients with type 1 diabetes than in patients with type 2 diabetes. The study included a number of 56 patients, who presented themselves for performing an implant. Of these, 7 patients did not perform an implant. Diabetes mellitus defines a chronic metabolic disorder, which may have multiple etiopathogenesis, characterized by changes in carbohydrate, lipid and protein metabolism. Stability of the implant in the bone, immediately after implantation is crucial for the success of the treatment; this immediate stability is called primary stability and is purely mechanical in nature. Keywords: Dental implants, dental treatments, diabetes, failure rate

scholarly journals Awareness among Patients regarding Dental Implants as a Treatment Option for replacing Missing Teeth in Melmaruvathur Population

2016 ◽  
Vol 6 (1) ◽  
pp. 6-9 ◽  
Author(s):  
Venkatesan Narayanan ◽  
Prabhu Karuppiah ◽  
Arunkumar Rajasekar ◽  
Lakshmi D Mayavan
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Treatment Option ◽  
Tamil Nadu ◽  
Dental Education ◽  
Education Programs ◽  
Missing Teeth ◽  
Oral Rehabilitation ◽  
Implant Therapy ◽  
Knowledge And Attitude

ABSTRACT Background Treatment with dental implants has become increasingly important in the range of prosthodontic treatment. Significant improvements in oral rehabilitation particularly in edentulous individuals have been seen. In Adhiparasakthi Dental College, Melmaruvathur, a survey was made to evaluate awareness among patients for dental implants, their level of knowledge, and attitude toward replacement of missing teeth by dental implants. Materials and methods A survey of 480 people was conducted through a printed questionnaire and completed by willing respondents. The questionnaires were prepared in English and Tamil language to enable better understanding and completion. Results Of the 510 people surveyed, 480 responses were retrieved, of which 331 were aware of dental implant treatment in Melmaruvathur, Tamil Nadu. Among them, 304 respondents were aware that implants could be used for replacement of missing teeth. Most of the respondents stated that dental implants were placed in the jawbone, followed by gums. Only 41% respondents assumed that implants last for a lifetime and only 35% of respondents believe that poor oral hygiene was the most common cause of implant failure. Conclusion More dental education programs are needed to improve understanding of the importance of restoration of missing teeth. General implant awareness levels are satisfactory. However, increased awareness of patients for restoration of missing tooth with dental implants is necessary. Dental education programs with special emphasis on advantages, treatment, maintenance, and postoperative care of dental implant therapy are needed. More than two-thirds of the surveyed population is interested in knowing about and being treated with dental implants. How to cite this article Narayanan V, Karuppiah P, Rajasekar A, Mayavan LD. Awareness among Patients regarding Dental Implants as a Treatment Option for replacing Missing Teeth in Melmaruvathur Population. Int J Prosthodont Restor Dent 2016;6(1):6-9.

Dental Implants for Patients with Periodontitis

2019 ◽  
Vol 8 (4) ◽  
pp. 54-61
Author(s):  
Rajiv M. Patel
Keyword(s):  
Treatment Planning ◽  
Dental Implants ◽  
Dental Implant ◽  
Narrative Review ◽  
Professional Support ◽  
Implant Therapy ◽  
Plaque Control ◽  
Partially Dentate ◽  
Implant Treatment

This article provides a narrative review of the use of dental implants in patients with periodontitis. Using clinical examples where possible, consideration is given to the survival and success of implants, peri-implantitis, comparison of periodontally compromised teeth to implants and to treatment planning to help achieve favourable outcomes. The challenges associated with restoring an edentulous arch or partially dentate dentition with implants where significant alveolar atrophy has occurred can be considerable. Compromised outcomes may be commonplace. Dental implant treatment is more likely to be successful for those patients who attain and maintain excellent plaque control. Professional support should focus on managing underlying periodontitis prior to commencing implant therapy and providing long term, regular supportive periodontal care upon completion of treatment.

scholarly journals Comparative Evaluation of Dental Implant Failure among Healthy and Well-Controlled Diabetic Patients—A 3-Year Retrospective Study

2020 ◽  
Vol 17 (14) ◽  
pp. 5253 ◽  
Author(s):  
Mohammed Ghazi Sghaireen ◽  
Abdulrahman A. Alduraywish ◽  
Kumar Chandan Srivastava ◽  
Deepti Shrivastava ◽  
Santosh R Patil ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Retrospective Study ◽  
Dental Implants ◽  
Dental Implant ◽  
Failure Rate ◽  
Control Group ◽  
Case Group ◽  
Diabetic Patients ◽  
Oral Rehabilitation ◽  
Operative Evaluation

Diabetes mellitus is known to compromise the various aspects of homeostasis, including the immune response and the composition of oral microflora. One of the oral manifestations of diabetes mellitus is tooth loss and the survival rate of dental implants chosen as a treatment modality for its rehabilitation is controversial. The current study aims to evaluate and compare the failure rate of dental implants between well-controlled diabetic and healthy patients. A retrospective study of case-control design was conceptualized with 121 well-controlled diabetic and 136 healthy individuals. Records of subjects who had undergone oral rehabilitation with dental implants between the periods of January 2013 to January 2016 were retrieved. Post-operative evaluation was carried out for all patients for about three years to assess the immediate and long-term success of the procedure. From a total of 742 dental implants, 377 were placed in well-controlled diabetic patients (case group) and 365 in healthy subjects (control group). A comparable (9.81%), but non-significant (p = 0.422) failure rate was found in the case group in comparison to the control group (9.04%). A non-significant (p = 0.392) raised number (4.98%) of failure cases were reported among females in comparison to males (4.44%). In respect to arch, the mandibular posterior region was reported as the highest failure cases (3.09%; p = 0.411), with 2.29% of cases reported in the mandibular anterior (p = 0.430) and maxillary posterior (p = 0.983) each. The maxillary anterior region was found to have the least number (1.75%; p = 0.999) of failure cases. More (4.98%; p = 0.361) cases were reported to fail during the functional loading stage in contrast to osseointegration (4.44%; p = 0.365). A well-controlled diabetic status does not impose any additional risk for individuals undergoing dental implant therapy.

scholarly journals Failure of dental implants in cemento-osseous dysplasia: a critical analysis of a case

2014 ◽  
Vol 43 (3) ◽  
pp. 223-227 ◽  
Author(s):  
Maiolino Thomaz Fonseca OLIVEIRA ◽  
Sérgio Vitorino CARDOSO ◽  
Cláudia Jordão SILVA ◽  
Darceny ZANETTA-BARBOSA ◽  
Adriano Mota LOYOLA
Keyword(s):  
Case Report ◽  
Dental Implants ◽  
Dental Implant ◽  
Critical Analysis ◽  
Bone Diseases ◽  
Limiting Factor ◽  
Oral Rehabilitation ◽  
Present Case Report ◽  
Osseous Dysplasia ◽  
And Behavior

Introduction: Osseointegrated dental implants have been routinely used in oral rehabilitation. Patients with dysplastic bone diseases represent a particular challenge for oral rehabilitation with dental implants. Nevertheless, the installation of implants in patients with cemento-osseous dysplasia (COD) has been reported with apparent success. Objective: In this paper, we present a case of a patient with COD in which a dental implant had been installed and lost six months later. In this regard, we analyzed pertinent aspects of the indications for dental implants in patients with COD considering the pathogenesis, dysplastic nature, and behavior of the disease. Conclusion: The present case report illustrates that COD can be considered a limiting factor in the recommendation for a dental implant. Because of this, it is imperative to inform the patient about the risks of surgically manipulating the diseased bone.

Assessment of Myeloperoxidase and Nitric Levels around Dental Implants and Natural Teeth as a Marker of Inflammation: A Comparative Study

2016 ◽  
Vol 17 (11) ◽  
pp. 934-938 ◽  
Author(s):  
Manish Kumar ◽  
Gayithri H Kulkarni ◽  
Prashant Jadhav ◽  
Kiran Kulkarni ◽  
Sachin V Shinde ◽  
...  
Keyword(s):  
Comparative Study ◽  
Dental Implants ◽  
Dental Implant ◽  
Plaque Index ◽  
Gingival Bleeding ◽  
Significant Difference ◽  
Inflammatory Processes ◽  
Natural Teeth ◽  
The Mean ◽  
Natural Tooth

ABSTRACT Introduction Dental implants form the mainstay of dental treatment involving rehabilitation of missing teeth. One of the major concerns for the clinicians doing dental implants is the postsurgical failure of dental implants. Success of dental implants is dependent upon the skills of the surgeon and the amount and quality of the bone remaining at the edentulous area where dental implant has to be placed. Myeloperoxidase (MPO) and nitrites are few of the enzymes and molecules which are said to be altered in inflammation. However, their exact role in the inflammatory processes around natural tooth and dental implant is still unclear. Hence we comparatively evaluated the levels of MPO and nitrites in the areas around the dental implants and natural teeth. Materials and methods The present study comprises 42 patients who underwent prosthetic rehabilitation by dental implants from 2011 to 2014. Depth of probing value (DP), score of plaque index (SPI), gingival index (GI), and index of gingival bleeding time (GBT) were evaluated for the assessment of the periimplant soft tissue changes. Assessment of inflammation around the dental implant surface and around natural tooth was done based on the readings of these parameters. For the measurement of the MPO levels, spectrophotometric MPO assay was used. All the results were analyzed by Statistical Package for the Social Sciences (SPSS) software. Results The mean plaque index values were 1.56 and 0.97 in periodontitis cases of natural teeth and inflamed cases of dental implants respectively. While comparing mean plaque index, mean probing depth, and mean gingival bleeding index in between the two groups, significant difference was obtained. Mean MPO concentration in periodontitis and gingivitis cases in natural teeth were 0.683 and 0.875 U/μL, while in inflamed dental implant cases, the mean value was 0.622 U/μL. While comparing the total MPO levels, total nitrite levels, and total nitrite concentration in between two study groups, significant difference was obtained. On comparing the healthy and periodontitis cases in natural teeth, significant difference was obtained. Conclusion In the inflammatory processes occurring around dental implant and natural teeth, MPO and NO make some amount of significant contribution. Clinical significance The present study enforces on the role of MPO and nitrite as diagnostic and prognostic marker. How to cite this article Kulkarni GH, Jadhav P, Kulkarni K, Shinde SV, Patil YB, Kumar M. Assessment of Myeloperoxidase and Nitric Levels around Dental Implants and Natural Teeth as a Marker of Inflammation: A Comparative Study. J Contemp Dent Pract 2016;17(11):934-938.

scholarly journals Subgingival Microbiome Colonization and Cytokine Production during Early Dental Implant Healing

mSphere ◽  
2017 ◽  
Vol 2 (6) ◽  
Author(s):  
Jeffrey B. Payne ◽  
Paul G. Johnson ◽  
Car Reen Kok ◽  
João C. Gomes-Neto ◽  
Amanda E. Ramer-Tait ◽  
...  
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Cytokine Production ◽  
Gingival Crevicular Fluid ◽  
Oral Microbiome ◽  
Anatomical Location ◽  
Implant Placement ◽  
Natural Teeth ◽  
Crevicular Fluid ◽  
Early Healing

ABSTRACT Little is known about longitudinal development of the peri-implant subgingival microbiome and cytokine production as a new sulcus forms after dental implant placement. Therefore, the purpose of this observational study was to evaluate simultaneous longitudinal changes in the oral microbiome and cytokine production in the developing peri-implant sulcus compared to control natural teeth. Four and 12 weeks after implant placement and abutment connection, a dental implant and a natural tooth were sampled in 25 patients for subgingival plaque and gingival crevicular fluid (GCF [around teeth] and peri-implant crevicular fluid [PICF] around implants). DNA from plaque samples was extracted and sequenced using Illumina-based 16S rRNA sequencing. GCF and PICF samples were analyzed using a customized Milliplex human cytokine and chemokine magnetic bead panel. Beta diversity analysis revealed that natural teeth and implants had similar subgingival microbiomes, while teeth had greater alpha diversity than implants. At the genus level, however, few differences were noted between teeth and dental implants over 12 weeks. Specifically, Actinomyces and Selenomonas were significantly elevated around teeth versus dental implants at both 4 weeks and 12 weeks, while Corynebacterium and Campylobacter were significantly elevated only at 4 weeks around teeth. The only difference between PICF and GCF biomarkers was significantly elevated granulocyte-macrophage colony-stimulating factor levels around teeth versus dental implants at the 4-week visit. The subgingival microbiome and cytokine production were similar between teeth and implants during early healing, suggesting that these profiles are driven by the patient following dental implant placement and are not determined by anatomical niche. IMPORTANCE Dental implants are a common treatment option offered to patients for tooth replacement. However, little is known regarding initial colonization of the subgingival microbiome and simultaneous longitudinal cytokine production in humans during the early healing phase following implant placement. We report findings from an in vivo study that assessed initial colonization of the subgingival microbiome and concomitant early cytokine production in a newly formed anatomical space, namely, an implant sulcus. This approach may be useful in future interventional studies to influence dental implant success. Our data showed that the subgingival microbiome and cytokine profile were similar for control natural teeth and dental implants at both 4 and 12 weeks after implant placement. These data suggest that these profiles are driven by the patient and not by anatomical location (i.e., tooth versus dental implant).

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