scholarly journals Impact of ApoE Polymorphism and Physical Activity on Plasma Antioxidant Capability and Erythrocyte Membranes

Antioxidants ◽  
2019 ◽  
Vol 8 (11) ◽  
pp. 538 ◽  
Author(s):  
Rebecca Piccarducci ◽  
Simona Daniele ◽  
Jonathan Fusi ◽  
Lucia Chico ◽  
Filippo Baldacci ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Membrane Fluidity ◽  
Positive Impact ◽  
Apoe Genotype ◽  
Well Being ◽  
Erythrocyte Membranes ◽  
Apoe Polymorphism ◽  
Plasma Antioxidant ◽  
The Impact ◽  
Regular Physical Exercise

The allele epsilon 4 (ε4) of apolipoprotein E (ApoE) is the strongest genetic risk factor for Alzheimer’s disease (AD). ApoE protein plays a pivotal role in the synthesis and metabolism of amyloid beta (Aβ), the major component of the extracellular plaques that constitute AD pathological hallmarks. Regular exercise is an important preventive/therapeutic tool in aging and AD. Nevertheless, the impact of physical exercise on the well-being of erythrocytes, a good model of oxidative stress and neurodegenerative processes, remains to be investigated, particularly depending on ApoE polymorphism. Herein, we evaluate the oxidative status, Aβ levels, and the membrane’s composition of erythrocytes in a cohort of human subjects. In our hands, the plasma antioxidant capability (AOC), erythrocytes membrane fluidity, and the amount of phosphatidylcholine (PC) were demonstrated to be significantly decreased in the ApoE ε4 genotype and non-active subjects. In contrast, erythrocyte Aβ content and lipid peroxidation increased in ε4 carriers. Regular physical exercise was associated with an increased plasma AOC and membrane fluidity, as well as to a reduced amount of erythrocytes Aβ. Altogether, these data highlight the influence of the ApoE genotype on erythrocytes’ well-being and confirm the positive impact of regular physical exercise.

Yoga as an Innovative Solution for Financial Growth of Companies

2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Ipseeta Satpathy ◽  
B. Chandra Mohan Patnaik ◽  
Chandrabhanu Das
Keyword(s):  
Inventory Management ◽  
Internal Control ◽  
Positive Impact ◽  
Cost Savings ◽  
Well Being ◽  
Primary Data ◽  
Financial Health ◽  
Antibiotic Drugs ◽  
Lifestyle Diseases ◽  
The Impact

The existence of Yoga dates back to more than ten thousand years around India and all nations. The Hindu Mythology considers the genesis of Yoga by incorporating Lord Shiva as Guru and Goddess Parvati as Shishya. Gradually with the development of civilization mankind assessed the benefits of this spiritual discipline and different leaders propagated the Yoga in different ways.In this era of 21st century Baba Ramdev propagated the yoga sutras with simple and effective techniques. The Pranayam and Suryanamaskar are the popular routines practiced by many followers of Baba Ramdev. Today Yoga is practiced as a way of Living to prevent Lifestyle diseases, combat stress and rejuvenate self. Yoga has gained immense popularity over the years with July 21st being celebrated as International Yoga Day. Corporate are also now introducing Yoga for employees as a means to relieve their stress and improve productivity. Long Hours of sitting, standing and excessive use of electronic gadgets puts pressure on bones, joints and responsible for Lifestyle diseases. Yoga is now increasingly used as a wellness solution replacing high cost antibiotic drugs. Employee well-being leads to Cost Savings in terms of personnel by reduced payment of Insurance and Medical Bills. The paper studies the Impact of Yoga to Financial benefits in MSME Organizations in Odisha in light of three different perspectives of Internal Control, Inventory management and Cash Flow. The primary data was collected from a sample of 155 high profile finance executives working in the MSME sector. Ranking Table and Regression Analysis Methodology was used to derive meaningful conclusions. The research takes initiative to transform the effectiveness of Yoga into improved financial health for the Organization. The observation from the study interprets a positive impact of Yoga on good financial health of Organization.

scholarly journals Social Evaluation of Public Open Space Services and Their Impact on Well-Being: A Micro-Scale Assessment from a Coastal University

2021 ◽  
Vol 13 (8) ◽  
pp. 4372
Author(s):  
Abdullah Addas ◽  
Ahmad Maghrabi
Keyword(s):  
Open Space ◽  
Environmental Changes ◽  
Positive Impact ◽  
Well Being ◽  
Social Evaluation ◽  
Open Spaces ◽  
Rapid Urbanization ◽  
Public Open Space ◽  
The Impact ◽  
Public Open Spaces

Public open spaces services have been shown to be profoundly affected by rapid urbanization and environmental changes, and in turn, they have influenced socio-cultural relationships and human well-being. However, the impact of these changes on public open space services (POSS) remains unexplored, particularly in the Saudi Arabian context. This study examines the socio-cultural influence of POSS on the King Abdulaziz University campus, Jeddah, Saudi Arabia and the impact of these services on well-being. A field survey and questionnaire were used to collect data. Non-parametric tests (Kruskal–Wallis and Mann–Whitney tests) were used to find significant differences in the importance of POSS as perceived by stakeholders based on socio-demographic attributes. Factor analysis was performed for 14 POSS to identify those that are most important. The study showed that (i) university stakeholders are closely linked to services provided by public open spaces (POS) and dependent on POSS, (ii) there were significant differences in the perceived importance of POSS according to gender, age, and social groups, and (iii) 70 to 90% of stakeholders reported POSS as having a positive impact on well-being. Thus, the findings will help design and plan POSS to meet the needs of society and promote well-being.

scholarly journals Modelling the comparative costs of Namaste Care: results from the namaste care intervention UK study

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Jennifer Bray ◽  
Dawn Brooker ◽  
Isabelle Latham ◽  
Darrin Baines
Keyword(s):  
Usual Care ◽  
Positive Impact ◽  
Cost Model ◽  
Well Being ◽  
Care Homes ◽  
Advanced Dementia ◽  
Content Type ◽  
Care Intervention ◽  
The Impact ◽  
Care Costs

Purpose The purpose of this paper is to populate a theoretical cost model with real-world data, calculating staffing, resource and consumable costs of delivering Namaste Care Intervention UK (NCI-UK) sessions versus “usual care” for care home residents with advanced dementia. Design/methodology/approach Data from five care homes delivering NCI-UK sessions populated the cost model to generate session- and resident-level costs. Comparator usual care costs were calculated based on expert opinion and observational data. Outcome data for residents assessed the impact of NCI-UK sessions and aligned with the resident-level costs of NCI-UK. Findings NCI-UK had a positive impact on residents’ physical, social and emotional well-being. An average NCI-UK group session cost £220.53, 22% more than usual care, and ran for 1.5–2 h per day for 4–9 residents. No additional staff were employed to deliver NCI-UK, but staff-resident ratios were higher during Namaste Care. Usual care costs were calculated for the same time period when no group activity was organised. The average cost per resident, per NCI-UK session was £38.01, £7.24 more than usual care. In reality, costs were offset by consumables and resources being available from stock within a home. Originality/value Activity costs are rarely calculated as the focus tends to be on impact and outcomes. This paper shows that, although not cost neutral as previously thought, NCI-UK is a low-cost way of improving the lives of people living with advanced dementia in care homes.

scholarly journals Legal Gender Recognition in Portugal: A Path to Self-Determination

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Carla Moleiro ◽  
Nuno Pinto
Keyword(s):  
Social Life ◽  
Positive Impact ◽  
Well Being ◽  
Clinical Report ◽  
Gender Recognition ◽  
Online Questionnaire ◽  
Psychological Well Being ◽  
Trans People ◽  
The Law ◽  
The Impact

<p><br />This paper presents research on the enforcement and impact of the first legal gender recognition legislation in Portugal (Law no.7/2011). The study describes how the administrative process created by the law functioned during its initial 5-year period, and identifies challenges and processes of resistance to this legal innovation. Simultaneously, it seeks to assess the impact of the law on the social and psychological well-being of trans people, including in their access to vital spheres of social life such as education and employment. The research employs a mixed-methods approach and a multi-informant methodology: an online questionnaire was completed by 68 trans and non-binary people, and semi-structured in-depth interviews were carried out with various selected stakeholders: representatives of trans and LGBTIQ+ organisations (n=5), health professionals identified as experts in the topic and as gatekeepers in legal gender recognition processes (n=12), and trans people (n=6). Results show, on the one hand, the significant positive impact that legal gender recognition has on the psychological well-being and social welfare of the participants. On the other hand, results also show several challenges and forms of resistance to the implementation of the law, in particular those challenges resulting from the fact that legal gender recognition depended on a clinical diagnosis and the provision of a clinical report.</p>

scholarly journals Perspectives of Entrepreneurial Orientation with the Quality of Life

2011 ◽  
Vol 3 (6) ◽  
pp. 388-394
Author(s):  
Salima Hafeez ◽  
Rashid Mehmood Chaudhry . ◽  
Muhammad Aslam Khan . ◽  
H.Mushtaq Ahmad . ◽  
Kashif Ur Rehman .
Keyword(s):  
Quality Of Life ◽  
Entrepreneurial Orientation ◽  
Third World ◽  
Dynamic Capabilities ◽  
Positive Impact ◽  
Well Being ◽  
Entrepreneurial Firms ◽  
The Third World ◽  
The Impact

The characteristics of entrepreneurial orientation is played important role in business. How do an entrepreneurial firms and individuals have taken the advantage in industry? This study explores the dynamic capabilities of the organization according to international performance. Our findings indicates the positive impact on dynamic capabilities of the business with perfectly use of this research framework. The main aspect of this paper is to analyse the impact of entrepreneurial orientation with the quality of life. Distinctive features of entrepreneurs and their contribution to the economy can make it possible for third world countries to grow their economies faster and provide financial means to enhance social, health, and environmental well-being (basic dimensions of quality of life), along with products and services that the poor need in these countries. Entrepreneurial orientation combined with organization learning and Quality of life (QOL) are enhanced the dynamic capability of the organization. Present conceptual research will provide the source of competitive advantage and mainstream line for further development of the business .We suggest that existing literature reconfiguring the different approaches for the entrepreneurial to capture the opportunities in world business. First, quality of life cannot possibly improve in inactive or weakening economic conditions; second, economic development in the third world countries cannot advance in a balanced and desirable manner without a major domestic entrepreneurship movement (Samli 2004, 2008a).

Psychosocial Consequences Among Nurses in the Affected Area of the Great East Japan Earthquake of 2011 and the Fukushima Complex Disaster: A Qualitative Study

2018 ◽  
Vol 13 (03) ◽  
pp. 519-526 ◽  
Author(s):  
Hideko Sato ◽  
Teeranee Techasrivichien ◽  
Atsuko Omori ◽  
Masako Ono-Kihara ◽  
Masahiro Kihara
Keyword(s):  
Qualitative Study ◽  
Interpersonal Relationships ◽  
Acute Stress ◽  
Positive Impact ◽  
Well Being ◽  
Great East Japan Earthquake ◽  
Family Responsibilities ◽  
Psychosocial Consequences ◽  
Mutual Care ◽  
The Impact

AbstractObjectiveThe goal of this study was to assess the psychosocial consequences among nurses affected by the Great East Japan Earthquake in order to identify their coping strategies and explore possible countermeasures against complex disasters.MethodsIn 2012, we conducted a qualitative study and screened participants for posttraumatic stress disorder (PTSD).ResultsThirty-eight nurses participated in this study. The result showed a relatively high proportion of probable PTSD (39%). Thirty-two conceptual codes emerged from the data and were grouped into 8 categories: “initial acute stress,” “acute stress turning chronic,” “chronic physical and mental fatigue,” “occupational stress,” “fear of the impact of radiation on children’s health,” “occupational satisfaction,” “positive influences of the disaster experiences,” and “impact of mutual care through interpersonal cognition.”ConclusionsThe study reveals that mutual care may have a positive impact in assisting recovery and enhancing the psychological well-being of nurses. We suggest that disaster management should take into consideration the conflict between professional and family responsibilities. In the light of the chronic impact of the nuclear crisis, enhanced support for interpersonal relationships and human resources, as well as appropriate safety precautions, is urgently needed to help affected nurses. (Disaster Med Public Health Preparedness. 2019;13:519-526)

‘Physical appearance and well-being in adults with incurable cancer: a thematic analysis’

2020 ◽  
pp. bmjspcare-2020-002632
Author(s):  
Philippa Tollow ◽  
Jane Ogden ◽  
Candida S McCabe ◽  
Diana Harcourt
Keyword(s):  
Thematic Analysis ◽  
Psychosocial Support ◽  
Positive Impact ◽  
Well Being ◽  
Emotional Impact ◽  
Structured Interviews ◽  
Incurable Cancer ◽  
The Impact ◽  
Appearance Changes

ObjectivesExisting research has established the importance of appearance concerns for individuals with cancer and identified appearance as an important factor in dying with dignity. No research, however, has explored in depth the role of appearance in the experiences of individuals who have incurable cancer. This research aims to explore patients’ experiences and perspectives in relation to the role of appearance issues in adults with incurable cancer.MethodsSemi-structured interviews were conducted with 24 adults with incurable cancer (20 women, 4 men; mean age 54.5, SD 11.32).ResultsThematic analysis generated three themes: ‘Identity: Embodying Cancer’, ‘Communication: Wearing your illness’ and ‘Support: Holistic Care’. Appearance was felt to be an important element of identity, which was often dominated by cancer, leading to feelings of separation from the participant’s previous self. Appearance changes also influenced the way in which individuals communicated with their external world, forcing discussion of their diagnosis, and increasing focus on their cancer, with participants having to manage the emotional impact of this on loved ones, as well as the impact on their legacy. Finally, participants highlighted the positive impact of appearance-related support in their well-being and identified peer connections and refocusing on the self as key elements of such support.ConclusionsAppearance changes play an important role in the experiences of individuals with incurable cancer with regards to both identity and communication and challenged participants’ ability to maintain normalcy. Further psychosocial support relating to appearance concerns was considered necessary to promote dignity and provide truly holistic patient care.

Mediating Role of Interpersonal Interactions Between Chinese Farmers' Social Networks and their Subjective Well-Being

2018 ◽  
Vol 46 (5) ◽  
pp. 721-732 ◽  
Author(s):  
Jianjun Zhang ◽  
Yang Xu ◽  
Yu Hou
Keyword(s):  
Social Networks ◽  
Rural Areas ◽  
Positive Impact ◽  
General Social Survey ◽  
Well Being ◽  
Psychological Needs ◽  
Mediating Effect ◽  
Subjective Well Being ◽  
Interpersonal Interactions ◽  
The Impact

As more than half the population of China lives in rural areas, farmers' subjective well-being is important to the maintenance of socialism in the countryside and the Chinese people's target of comprehensively building a prosperous society. Using data collected in the 2012 Chinese General Social Survey, we built a regression model to examine the impact of farmers' social networks on their subjective well-being, and the mediating effect of their interpersonal interactions on this relationship. Results showed that farmers' social networks had a positive impact on their overall subjective well-being, which was, in turn, mediated by their interpersonal interactions. Farmers with well-developed social networks tended to have effective interpersonal interactions that satisfied their social psychological needs and enhanced their subjective well-being. Our findings provide a valuable reference for enhancing the subjective well-being of farmers in China.

scholarly journals Economic Expectations of Young Adults

2018 ◽  
Vol 4 ◽  
pp. 237802311879595 ◽  
Author(s):  
Nina Bandelj ◽  
Yader R. Lanuza
Keyword(s):  
Young Adults ◽  
Social Relations ◽  
Positive Impact ◽  
Panel Study ◽  
Well Being ◽  
Moral Worth ◽  
Socioeconomic Background ◽  
Economic Expectations ◽  
Economic Future ◽  
The Impact

In uncertain economic times, who are those young adults that show positive expectations about their economic future? And who are those who worry? Based on previous stratification research and extending economic sociology insights into the realm of young people’s economic expectations, we focus on the impact of family class background and a sense of current meaningful community relations on young adults’ general and job-specific economic expectations. Analysis of Panel Study of Income Dynamics (PSID) data reveals that a sense of community belonging has a robust and positive impact on economic optimism of young adults, but the role of family socioeconomic background is weaker. We conclude that imagining one’s economic future is less about realistic calculation determined by early structural conditions but more about identity work of young people who assert their moral worth in how they imagine their economic lives and manage uncertainty and well-being in ongoing social relations.

scholarly journals The Impact of Routine Skin Care on the Quality of Life

Cosmetics ◽  
2020 ◽  
Vol 7 (3) ◽  
pp. 59 ◽  
Author(s):  
Lixia Zhang ◽  
Aldhel Adique ◽  
Pradipta Sarkar ◽  
Vinay Shenai ◽  
Murali Sampath ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Positive Impact ◽  
Test Group ◽  
Well Being ◽  
Consumer Products ◽  
Skin Care ◽  
Main Study ◽  
New Mothers ◽  
The Impact

Importance: Consumers purchase a wide variety of consumer products and come into contact with these products on a daily basis. Manufacturers invest deeply in developing new products or improving existing products, in order to produce a positive impact on the lives of consumers. Objective: The goal of this study was to determine the impact of over-the-counter skin care products on the quality of life (QoL) of female consumers. Design and Measures: A QoL instrument developed for consumer products (the Farage QoL with an added Skin Care Module) was used to assess the impact of a 28-day facial skin care regimen using commercially available products formulated to improve elasticity, firmness and hydration, and to correct age- and sun-related skin color. Responses were collected prior to study commencement, at completion of the product usage stage, and after a period of withdrawal of the product with reversion to a basic skin care regimen. Participants: Two main study groups from Australia included 89 new mothers, i.e., women with children 2 years and under (mean age ± SD was 34 ± 4.8), and a national representative sample of 91 women (45 ± 12). An additional test group from China consisted of 40 younger cosmetic users (25 ± 4.3). The Skin Care Module was not included in the instrument for the third group. Results: After 28-days of usage, both test groups in the main study showed significant improvement in three of five items in the Skin Care Module (improved feelings of empowerment, happiness and self-esteem). Improvements persisted after 2 weeks of product withdrawal. In the main QoL instrument, the New Mothers group showed significant improvement in the Well-Being domain, driven by improvements in the Self-Image and Self Competence subdomains. The National Representative group showed improvements in the Energy and Vitality domain, driven by improvements in the Personal Pleasure, Physical State and Routine Activity subdomains. The additional group in the China study showed results similar to the New Mothers group. Conclusions and Relevance: A quality and efficacious skin care regimen can have a positive impact on the QoL of consumers. Differences in responses of the test groups were likely related to differences in the mean age and differences in time available to look after themselves.

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