scholarly journals Exercise-Induced Muscle Damage and Oxidative Stress

Antioxidants ◽  
2018 ◽  
Vol 7 (4) ◽  
pp. 50 ◽  
Author(s):  
Athanasios Jamurtas
2014 ◽  
Vol 84 (3-4) ◽  
pp. 0163-0172 ◽  
Author(s):  
Ismail Boz ◽  
Muaz Belviranli ◽  
Nilsel Okudan

Aim: The purpose of this study was to investigate the effects of curcumin on eccentric exercise-induced muscle damage and oxidative stress in rats. Methods: Thirty male Wistar rats were divided into four groups: Control (C; no curcumin, no exercise; n = 6), Curcumin (Cur; n = 8), Exercise (E; n = 8) and Exercise Plus Curcumin (ECur; n = 8). Curcumin was given for 20 days via oral gavage at doses of 200 mg/kg-1 of body weight per day, dissolved in corn oil. On the 21st day eccentric exercise was provided via a treadmill run and the rats were sacrificed immediately after. Results: Eccentric exercise resulted in significant (p < 0.05) increases in all injury markers such as creatine kinase (CK) and myoglobin, but curcumin supplementation tended to decrease CK activity (p > 0.05) and significantly decreased myoglobin levels (p < 0.05). In blood and muscle samples, malondialdehyde (MDA) levels were not affected by either curcumin or exercise (p > 0.05). MDA levels in liver tissue decreased in the ECur group, compared to the control (p < 0.05). Superoxide dismutase (SOD) activities and glutathione (GSH) levels were affected by neither curcumin nor exercise (p > 0.05), in blood, muscle and liver tissues. Conclusion: The results of this study suggest that curcumin has a protective effect on eccentric exercise induced muscle damage, and that this effect might be independent of oxidative stress and antioxidant systems.


2021 ◽  
pp. 194173812110364
Author(s):  
Daniel Rojano-Ortega ◽  
José Peña Amaro ◽  
Antonio J. Berral-Aguilar ◽  
Francisco J. Berral-de la Rosa

Context: Beetroots have antioxidant and anti-inflammatory properties, which may help attenuate inflammation and oxidative stress, enhancing recovery from exercise-induced muscle damage (EIMD). Objective: To evaluate the effects of beetroot supplementation on oxidative stress, inflammation, and recovery after EIMD. Data Sources: SPORTDiscus, PubMed, Web of Science, and Scopus databases were searched, and hand-searching was performed by looking to relevant studies that were cited in other studies. Study Selection: For a study to be included in this review, the following inclusion criteria had to be met: (1) research conducted with human participants, (2) original articles in peer-reviewed publications, (3) original studies that had investigated beetroot supplementation intervention on muscle damage and recovery, (4) research conducted with 1 control/placebo group, and (5) articles published from inception to October 2020. Study Design: Systematic review using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. Level of Evidence: Level 3. Data Extraction: Two of the 4 authors independently extracted data and assessed the methodological quality of the articles with the PEDro scale. All discrepancies were resolved through a consensus meeting. Results: A total of 9 studies were included in this review. The methodological quality of the included studies ranged from moderate to high. Most of the studies found a better recovery of functional variables and muscle soreness, but improvements in markers of muscle damage, inflammation, and oxidative stress were not reported. Conclusion: The existing evidence suggests that a short-term beetroot supplementation has the potential to accelerate recovery of functional measures and muscle soreness, but further research is needed to clarify if a longer supplementation period (with some days before exercise and some days after) could also promote recovery of markers of muscle damage, inflammation, and oxidative stress.


2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Marco Malaguti ◽  
Cristina Angeloni ◽  
Silvana Hrelia

Although moderate physical exercise is considered an essential component of a healthy lifestyle that leads the organism to adapt itself to different stresses, exercise, especially when exhaustive, is also known to induce oxidative stress, inflammation, and muscle damage. Many efforts have been carried out to identify dietary strategies or micronutrients able to prevent or at least attenuate the exercise-induced muscle damage and stress. Unfortunately most studies have failed to show protection, and at the present time data supporting the protective effect of micronutrients, as antioxidant vitamins, are weak and trivial. This review focuses on those polyphenols, present in the plant kingdom, that have been recently suggested to exert some positive effects on exercise-induced muscle damage and oxidative stress. In the last decade flavonoids as quercetin, catechins, and other polyphenols as resveratrol have caught the scientists attention. However, at the present time drawing a clear and definitive conclusion seems to be untimely.


2021 ◽  
Vol 12 (7) ◽  
pp. 3132-3141
Author(s):  
Hongkang Zhu ◽  
Wenqian Xu ◽  
Ning Wang ◽  
Wenhao Jiang ◽  
Yuliang Cheng ◽  
...  

We investigated the role of Maca aqueous extract on muscle during exercise-induced fatigue both in vivo and in vitro..


2015 ◽  
Vol 47 ◽  
pp. 646
Author(s):  
Kevin Schill ◽  
Alex Altenburger ◽  
Alex Fultz ◽  
Jeovanna Lowe ◽  
Muthu Periasamy ◽  
...  

2010 ◽  
Vol 9 (1) ◽  
Author(s):  
Richard J Bloomer ◽  
Robert E Canale ◽  
Megan M Blankenship ◽  
Kelsey H Fisher-Wellman

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