scholarly journals Effects of Resveratrol on Growth Performance, Intestinal Development, and Antioxidant Status of Broilers under Heat Stress

Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1427
Author(s):  
Chi Wang ◽  
Fei Zhao ◽  
Zhen Li ◽  
Xu Jin ◽  
Xingyong Chen ◽  
...  
Keyword(s):  
Heat Stress ◽  
Antioxidant Capacity ◽  
Growth Performance ◽  
Related Factor ◽  
Mrna Levels ◽  
Intestinal Development ◽  
Villus Height ◽  
Final Body Weight ◽  
Treatment Groups ◽  
Nrf2 Signaling Pathway

The study investigated resveratrol’s effect on growth performance, intestinal development, and antioxidant capacity of broilers subjected to heat stress (HS). A total of 162 21-day-old male AA broilers were randomly divided into 3 treatment groups with 6 replicates of 9 birds each. The 3 treatment groups were as follows: the control (CON), in which broilers were housed at 22 ± 1 °C for 24 h day−1, and the HS and HS + resveratrol (400 mg/kg) groups, in which broilers were housed at 33 ± 1 °C for 10 h a day from 8:00 to 18:00 and 22 ± 1 °C for rest of the time. Results indicated that birds in the HS group exhibited lower (p < 0.05) final body weight (BW) and average daily gain (ADG) compared with birds in the CON group. HS birds also had lower (p < 0.05) relative jejunum weight, relative ileum and jejunum length, jejunal villus height, and villus height to crypt depth ratios than the CON group. The activities of glutathione peroxidase (GPX), glutathione S-transferase (GST), superoxide dismutase (SOD), and the mRNA levels of NF-E2-related factor 2 (Nrf2), SOD1, and GPX were also lower (p < 0.05) in the HS than CON group. The HS group had higher (p < 0.05) protein carbonyl (PC) contents and Kelch-like ECH-associated protein 1 (Keap1) mRNA levels. Compared with HS group, the HS + resveratrol group exhibited higher (p < 0.05) BW and ADG, relative jejunum weight, relative length of ileum, jejunal villus height, activities of GPX and GST, and mRNA levels of Nrf2 and SOD1, but they had lower (p < 0.05) PC content and Keap1 mRNA levels. In conclusion, resveratrol can improve the intestinal development and antioxidant function of broilers under HS, and therefore improve growth performance. The mechanism by which resveratrol enhances the intestinal antioxidant capacity is mediated by Nrf2 signaling pathway.

scholarly journals Algae-Derived Polysaccharides Promote Growth Performance by Improving Antioxidant Capacity and Intestinal Barrier Function in Broiler Chickens

2020 ◽  
Vol 7 ◽  
Author(s):  
Wen-Chao Liu ◽  
Yan Guo ◽  
Zhi-Hui Zhao ◽  
Rajesh Jha ◽  
Balamuralikrishnan Balasubramanian
Keyword(s):  
Antioxidant Capacity ◽  
Growth Performance ◽  
Average Daily Gain ◽  
Intestinal Morphology ◽  
Intestinal Barrier Function ◽  
Control Group ◽  
Gut Health ◽  
Feed Conversion ◽  
Villus Height ◽  
Final Body Weight

This study aimed to determine the efficacy of dietary algae-derived polysaccharides (ADPs) from Enteromorpha on growth performance, intestinal morphology, intestinal permeability, and antioxidant capacity in serum, liver, and intestinal mucosa of broilers. Three hundred and ninety six day-old male chicks were randomly assigned to six dietary treatments containing 0 (Control), 1,000, 2,500, 4,000, 5,500, and 7,000 mg ADP/kg basal diet in a 35 day feeding trial. During day 1–21, compared with the control group, dietary 1,000–7,000 mg/kg ADP supplementation improved the average daily gain (ADG) and feed conversion ratio (p &lt; 0.05). Overall (day 1–35), dietary inclusion of 1,000 mg/kg ADP increased the final body weight and ADG (p &lt; 0.05). Besides, on day 21, dietary 2,500 mg/kg ADP supplementation increased the serum catalase (CAT) and liver total superoxide dismutase (T-SOD) activities (p &lt; 0.05), whereas dietary 1,000–5,500 mg/kg ADP supplementation decreased malondialdehyde (MDA) contents in serum and liver (p &lt; 0.05). On day 35, supplementation of 1,000 mg/kg ADP increased the serum glutathione peroxidase and CAT activities and liver T-SOD activities (p &lt; 0.05). It decreased the MDA level of serum and liver (p &lt; 0.05). Also, dietary 2,500 mg/kg ADP increased the villus height of jejunum and ileum on day 21 (p &lt; 0.05), and dietary 4,000 mg/kg ADP increased the villus height of duodenum and ileum on day 35 (p &lt; 0.05). On day 21, dietary 4,000 mg/kg ADP increased the CAT activities of the duodenum and T-SOD activities of jejunum and ileum and decreased the MDA contents in the duodenum, jejunum, and ileum (p &lt; 0.05). On day 35, dietary inclusion of 1,000–7,000 mg/kg ADP reduced MDA contents of duodenum and jejunum (p &lt; 0.05). Furthermore, dietary inclusion of ADP at 1,000–7,000 mg/kg decreased serum DAO activities at day 21 and day 35 (p &lt; 0.05), and the serum D-lactic acid concentration was reduced by dietary supplementation of 1,000, 2,500, and 7,000 mg/kg ADP on day 21. In conclusion, dietary ADP exerted beneficial effects on growth performance, antioxidant capacity, and gut health in broilers; based on the studied parameters, the appropriate recommended dose is 1,000–4,000 mg/kg. These findings provided new insights into the potential application of ADP as natural growth promoters in broilers.

Effects of dietary rosemary extract supplementation on growth performance, nutrient digestibility, antioxidant capacity, intestinal morphology and microbiota of weaning pigs

2021 ◽  
Author(s):  
Mei Yang ◽  
Yexin Yin ◽  
Fang Wang ◽  
Xuetai Bao ◽  
Lina Long ◽  
...  
Keyword(s):  
Body Weight ◽  
Antioxidant Capacity ◽  
Growth Performance ◽  
Biological Activities ◽  
Nutrient Digestibility ◽  
Intestinal Morphology ◽  
Weaned Piglets ◽  
Villus Height ◽  
Final Body Weight ◽  
Crypt Depth

Abstract Rosemary (Rosmarinus officinalis L.) extract (RE) has multiple pharmacological and biological activities, including use as a food additive and medicine. This study was conducted to investigate the effects of dietary RE supplementation on the growth performance, nutrient digestibility, antioxidant capacity, intestinal morphology and microbiota of weaning piglets. A total of 192 crossbred weaned piglets [Duroc × (Large White × Landrace)] (initial body weight = 6.65 ± 0.33 kg, weaned days = 23 ± 1 d) were group housed (six pigs per pen; n = 8 pens/treatment). Pigs were fed a corn-soybean meal-based control diet or the basal diet supplemented with 100, 200 or 400 mg/kg RE. Pigs were allowed ad libitum access to fed for 21-d. The growth performance and apparent total tract digestibility of nutrients, and intestinal morphology and antioxidant status were evaluated. The components of the microbial microflora were also determined in the cecal samples. Compared with the control, dietary supplementation with RE increased the final body weight, average daily gain and average daily feed intake (linear, P = 0.038, 0.016, and 0.009, respectively), and decreased the diarrhea ratio in piglets (linear, P &lt; 0.05). The digestibility of crude protein (linear, P = 0.034) and gross energy (linear, P = 0.046) increased with treatment with RE. Piglets fed RE showed longer villus height (linear, P = 0.037 and 0.028, respectively) and villus height/crypt depth (linear, P = 0.004 and 0.012; quadratic, P = 0.023 and 0.036, respectively) in the jejunum and ileum, in addition to a lesser crypt depth in the jejunum (linear, P = 0.019) and ileum (quadratic, P = 0.042). The addition of RE increased the activity of superoxide dismutase (linear, P = 0.035 and 0.008 respectively) and glutathione peroxidase activity (linear, P = 0.027 and 0.039 respectively), and decreased the content of malondialdehyde (linear, P = 0.041 and 0.013; quadratic, P = 0.023 and 0.005 respectively) in the serum and liver. Dietary RE supplementation, compared with the control, increased the number of Bifidobacterium (linear, P = 0.034) and Bacteroidetes (linear, P = 0.029), while decreased Escherichia coli (linear, P = 0.008; quadratic, P = 0.014) in the cecal contents. Thus, dietary RE supplementation can improve growth performance, nutrient digestibility, antioxidant capacity, intestinal morphology and the microbiota in weaned piglets, and 200 mg/kg may be considered the optimum dosage.

scholarly journals Effect of extruded full-fat soybeans on performance, amino acids digestibility, trypsin activity, and intestinal morphology in broilers

2013 ◽  
Vol 58 (No. 10) ◽  
pp. 470-478 ◽  
Author(s):  
M. Foltyn ◽  
V. Rada ◽  
M. Lichovníková ◽  
I. Šafařík ◽  
A. Lohniský ◽  
...  
Keyword(s):  
Amino Acids ◽  
Body Weight ◽  
Growth Performance ◽  
Intestinal Morphology ◽  
Trypsin Activity ◽  
Villus Height ◽  
Isoleucine Leucine ◽  
Final Body Weight ◽  
Dietary Treatments ◽  
Different Levels

The influence of different levels of extruded full-fat soybean (EFFSB) in the diet on growth performance, apparent ileal amino acids digestibility (AIAAD), intestinal morphology, and trypsin activity in digesta of broilers was determined. In the first experiment, two-hundred sixty ROSS 308 male chickens were used to investigate the effect of EFFSB on growth performance, intestinal morphology, and trypsin activity in the digesta and AIAAD. Five dietary treatments were used, containing 0, 40, 80, 120, and 160 g/kg of EFFSB. The experiment lasted from day 10 till day 38 of age. The inclusion of EFFSB at the level of 160 g/kg in the diet significantly (P &lt; 0.05) decreased final body weight (2443 g in 0 group vs. 2093 in 160 group) and worsened feed efficiency. AIAAD was lower when diet contained more than 40 g/kg EFFSB. But at the level of 160 g/kg AIAAD increased in several amino acids (threonine, isoleucine, leucine, histidine). Trypsin activity increased with increasing EFFSB in the diets. There were no significant (P &gt; 0.05) differences in AIAAD between groups 80, 120, and 160. Villus height (groups 0: 966.2; 4: 852.1; 8: 792.6; 12: 836.3; 16: 926.7 &micro;m) and crypt depth (groups&nbsp;0: 160.1; 4: 134.8; 8: 122.9; 12: 129.5; 16: 134.6 &micro;m) of ileum decreased with inclusion of EFFSB in the diet, but villi/crypt ratio increased. In the second experiment, male chickens ROSS 308 were divided into 4&nbsp;groups with 2 replicates per 100 chicks each. The groups were fed 0, 40, 80, and 120 g/kg of EFFSB. The experiment lasted from day 10 till day 38 of age. Final body weight (2594 g in 0 group vs. 2624 g in 120 group) was not significantly (P &gt; 0.05) affected by the diet. The study showed that EFFSB at the level of 120 g/kg in grower broiler diet had no adverse effect on performance. &nbsp;

scholarly journals Effects of dietary fumaric acid on the growth performance, immune response, relative weight and antioxidant status of immune organs in broilers exposed to chronic heat stress

2020 ◽  
Vol 65 (No. 3) ◽  
pp. 104-113 ◽  
Author(s):  
Shaojun He ◽  
Qirun Yin ◽  
Yongjie Xiong ◽  
Deyi Liu ◽  
Hong Hu
Keyword(s):  
Heat Stress ◽  
Immune Function ◽  
Growth Performance ◽  
Fumaric Acid ◽  
Antioxidant Status ◽  
Immune Organ ◽  
Final Body Weight ◽  
Immune Organs ◽  
Organ Index ◽  
Antibody Titres

This study aimed to investigate the effects of dietary fumaric acid (FA) on growth performance, immune responses, immune organ index and antioxidant status in broilers under chronic heat stress (HS). A total of 200 21-day-old Ross 308 chicks were randomly assigned in a 2 × 2 factorial arrangement with two diets (basal diet or 10 g/kg FA diet) and two temperatures (thermoneutral or HS) for 21 days. On day 42, growth performance, immune organ index, immune function and antioxidative ability were determined. HS resulted in a significant reduction in final body weight (FBW), average daily feed intake (ADFI), average daily gain (ADG), antibody titres against sheep red blood cells (SRBC) and Newcastle disease virus, IgM, IgG, relative weights of spleen, thymus and bursa of Fabricius, but a significant increase in the feed conversion ratio (FCR), activities of total superoxide dismutase (T-SOD) and glutathione peroxidase (GPx) in the bursa, contents of malondialdehyde and total carbonyl (TC) in thymus and bursa (P &lt; 0.05). Dietary supplementation of FA increased FBW, ADFI, ADG, antibody titres against SRBC, IgG, relative weights of spleen and bursa, activity of GPx in thymus and bursa, whereas it decreased the FCR and TC of thymus and bursa. These results suggest that dietary 10 g/kg FA had positive effects on growth performance and immune function through improving the antioxidative capacity of immune organs.

scholarly journals New insights into the role of chitosan oligosaccharide in enhancing growth performance, antioxidant capacity, immunity and intestinal development of weaned pigs

RSC Advances ◽  
2017 ◽  
Vol 7 (16) ◽  
pp. 9669-9679 ◽  
Author(s):  
Jin Wan ◽  
Fei Jiang ◽  
Qingsong Xu ◽  
Daiwen Chen ◽  
Bing Yu ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Growth Performance ◽  
Chitosan Oligosaccharide ◽  
Intestinal Development ◽  
Weaned Pigs ◽  
Growth Stimulant

Chitosan oligosaccharide (COS), an oligomer ofd-glucosamine, is a vital growth stimulant in the pig industry.

scholarly journals Natural astaxanthin enhanced antioxidant capacity and improved semen quality through the MAPK/Nrf2 pathway in aging layer breeder roosters

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Shan Gao ◽  
Nuo Heng ◽  
Fang Liu ◽  
Yong Guo ◽  
Yu Chen ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Hydroxyl Radicals ◽  
Semen Quality ◽  
Antioxidant Properties ◽  
Mitogen Activated Protein Kinase ◽  
Control Group ◽  
Antioxidant Enzyme Activities ◽  
Related Factor ◽  
Mrna Levels ◽  
Nrf2 Pathway

Abstract Background Natural astaxanthin (ASTA) has strong antioxidant properties and has been widely used as a health product to improve human health. However, the effects of ASTA on the reproductive performance of aging roosters have been poorly studied. We aimed to investigate the effects of dietary ASTA on semen quality and antioxidant capacity in aging roosters and to explore the potential mechanism of semen quality change via anti-oxidation defense system. Methods In the present study, 96 53-week-old Jinghong No. 1 layer breeder roosters were fed a corn-soybean meal basal diet containing 0, 25, 50, or 100 mg/kg ASTA for 6 weeks. Results Semen quality in the ASTA groups remarkably improved than that in the control group, and antioxidant activities, the abilities to scavenge hydroxyl radicals and superoxide anions, increased gradually with ASTA addition (P < 0.05). In addition, the mRNA levels of antioxidant enzymes as well as the mRNA and protein levels of the mitogen-activated protein kinase (MAPK) and nuclear factor-erythroid 2-related factor 2 (Nrf2) were markedly increased in the 50–100 mg/kg ASTA group (P < 0.05). Conclusions Collectively, these results demonstrate that dietary ASTA may improve semen quality by increasing antioxidant enzyme activities and the ability to scavenge hydroxyl radicals, which may be related to upregulation of the MAPK/Nrf2 pathway.

scholarly journals Effect of Supplementation Yeast Fermentation Products on Growth Performance and Intestinal Health of Weaned Piglets Challenged With Salmonella Typhimurium

2021 ◽  
Author(s):  
Yongsen Zhao ◽  
Danping Wang ◽  
Meng Jiang ◽  
Jinglong Chen ◽  
Xiaojing Yang
Keyword(s):  
Growth Performance ◽  
Intestinal Inflammation ◽  
Yeast Fermentation ◽  
Mrna Levels ◽  
Weaned Piglets ◽  
Villus Height ◽  
Fermentation Products ◽  
Positive Effects ◽  
Fermentation Product ◽  
Challenge Control

Abstract Background: This study investigated the effects of piglets with dietary supplementation yeast fermentation product (YFP) on growth performance, immune status and intestinal inflammation after a Salmonella typhimurium challenge. Twenty-four weaned piglets were assigned to four treatments including: non-challenge control (Con); Salmonella typhimurium-challenged control (ST); ST + 0.2% YFP (0.2% YFP); and ST + 0.4% YFP (0.4% YFP). All piglets were challenged twice with Salmonella typhimurium. All of them were killed at 7th day after the second challenge to obtain plasma and intestine for analysis.Results: 0.4% YFP increased average daily gain (ADG) and duodenal villus height and villus height/ crypt depth (P < 0.05) and decreased feed-gain ratio (P < 0.05) after Salmonella typhimurium challenge compared with ST group. The 0.4% YFP decreased the elevating concentrations IL-1b and IL-6 (P < 0.01) induced by Salmonella typhimurium and increased the concentration of IL-10 (P < 0.05) in plasma compared with ST group. Furthermore, YFP influenced the apoptosis related mRNA levels of Bax, Bcl-2 and caspase 3 (P < 0.05) and increased intestinal occludin protein expression (P < 0.05). 0.4% YFP down-regulated the mRNA expressions of TLR4, MyD88, IRAK1, TRAF6 and NFkB (P < 0.05) and decreased the mRNA expression of IL-6, TNFa (P < 0.05) and increased the IL-10 (P < 0.01) in duodenum compared with ST group. In addition, 0.4% YFP decreased the phosphorylation levels of p38 MAPK and ERK1/2 (P < 0.01).Conclusions: Dietary 0.4% yeast fermentation product supplementation had positive effects on growth performance and intestinal barrier function and reduced intestinal inflammation of weaned piglets challenged with Salmonella typhimurium.

scholarly journals Growth performance, carcass characteristics, digestibility and economics of broiler production fed diets containing different levels of camel rumen content in the Semi- Arid Zone of Nigeria

2020 ◽  
Vol 44 (5) ◽  
pp. 82-92
Author(s):  
G. Mohammed ◽  
L. G. Asheikh ◽  
U. M. Kolo ◽  
F. I. Abbator ◽  
Z. M. Chana ◽  
...  
Keyword(s):  
Weight Gain ◽  
Growth Performance ◽  
Daily Weight Gain ◽  
Rumen Content ◽  
Test Material ◽  
Final Body Weight ◽  
Treatment Groups ◽  
Groundnut Cake ◽  
Carcass Parameters ◽  
Different Levels

The feeding value of different levels of camel rumen content in broiler diet was investigated using 150 Hover marshal broiler chickens from one-day to 63-days of age. The birds were randomly allotted to five /diets with two replicates of 15 birds each. The diets (starter and finisher) were formulated to contain 0, 5, 10, 15 and 20% camel rumen content in T1, T2, T3, T4 and T5 diets respectively. At nine week of the experiment three birds per replicate were selected for carcass measurement. The backs, hearts, kidneys, lungs, liver and spleen were not significantly (P > 0.05) different among the treatment groups while other parameters were significantly (P<0.05) different among the treatment groups. At week eight of the experiment three birds per replicate were selected for digestibility study. At the starter stage, the daily feed intake and daily weight gain were significantly (P<0.05) different among the treatment groups but only the feed conversion ratio was not affected (P>0.05) by the camel rumen content (CRC) in the diets. However, broiler chicks fed CRC T1 (0%), T2 (5%), T3 (10%) and T4 (15%) had better daily weight gain than those fed T5 (20%). During the finisher stage, all the growth parameters were not affected (P>0.05%) by CRC except final body weight which was affected (P<0.05) by the test material. Economic of production showed that CRC diets were not profitable in terms of cost of feed per kg weight gain during the starter stage. At finisher stage the cost of feed per kg weight gain were better in broilers chicken fed CRC based-diets. The result of the experiment showed that camel rumen content can replace maize and groundnut cake up to 15% level without deleterious effect on the roductive performance of broiler chicks.However, at finisher stage up to20%dietarymaize and groundnut cake could be replaced with CRC without adverse effect on the growth performance, carcass parameters, digestibility and economics of production.

scholarly journals Effects of Dietary Betaine on Growth Performance, Digestive Function, Carcass Traits, and Meat Quality in Indigenous Yellow-Feathered Broilers under Long-Term Heat Stress

Animals ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 506 ◽  
Author(s):  
Liu ◽  
Yuan ◽  
Sun ◽  
Balasubramanian ◽  
Zhao ◽  
...  
Keyword(s):  
Heat Stress ◽  
Growth Performance ◽  
Feed Intake ◽  
Nitrogen Retention ◽  
Basal Diet ◽  
Control Group ◽  
Trypsin Activity ◽  
Villus Height ◽  
Betaine Supplementation

Heat stress has a profound effect on poultry health and productivity. The present study evaluated whether feeding betaine could ameliorate long-term heat stress-induced impairment of productive performance in indigenous yellow-feathered broilers. A total of 240 five-week-old male broilers were randomly allocated to five treatments with six replicates of eight broilers each. The five treatments included a thermoneutral zone control group (TN, fed basal diet), a heat stress control group (HS, fed basal diet), and an HS control group supplemented 500, 1000, 2000 mg/kg betaine, respectively. The TN group was raised at 26 ± 1 °C during the whole study, HS groups exposed to 32 ± 1 °C for 8 h/day from 9:00 am to 17:00 pm. The results showed that heat stress decreased the body weight gain (BWG) and feed intake of broilers during 1–5, 6–10, and 1–10 weeks (p < 0.05). Dietary betaine tended to improve the BWG and feed intake of broilers under 5 weeks of heat stress (linear, p < 0.10), and betaine supplementation linearly increased the BWG and feed intake during 6–10 and 1–10 weeks (p < 0.05). Additionally, nitrogen retention was reduced by 5 weeks and 10 weeks of heat stress (p < 0.05), whereas dietary betaine could improve nitrogen retention in heat stressed broilers after both 5 and 10 weeks of heat stress (linear, p < 0.05). Moreover, this study observed that the trypsin activity of jejunum was decreased by 5 weeks of heat stress (p < 0.05), whereas betaine supplementation had quadratic effects on trypsin activity of jejunum in heat stressed broilers (p < 0.05). Furthermore, 10 weeks of heat stress induced a reduction of villus height of the duodenum and jejunum (p < 0.05), and decreased the villus height to crypt depth ratio of the jejunum (p < 0.05). Supplementation with betaine ameliorated the adverse effects of heat stress on these parameters (p < 0.05). Compared with the TN group, 10 weeks of heat stress reduced carcass and breast yield (p < 0.05) and betaine supplementation improved carcass and breast yield of heat stressed broilers (linear, p < 0.05). In conclusion, dietary supplementation of betaine could reduce the detrimental effects of long-term heat stress on growth performance, digestive function, and carcass traits in indigenous yellow-feathered broilers.

scholarly journals Effects of Dietary Resveratrol Supplementation on Growth Performance and Anti-Inflammatory Ability in Ducks (Anas platyrhynchos) through the Nrf2/HO-1 and TLR4/NF-κB Signaling Pathways

Animals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3588
Author(s):  
Hao Yang ◽  
Yingjie Wang ◽  
Mengru Liu ◽  
Xiao Liu ◽  
Yihan Jiao ◽  
...  
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Signaling Pathways ◽  
Anas Platyrhynchos ◽  
Average Daily Gain ◽  
Dietary Treatment ◽  
Mrna Levels ◽  
Final Body Weight ◽  
Specific Pathogen ◽  
Anti Inflammatory

The aim of this study was to explore the effect of dietary resveratrol on the growth performance and anti-inflammatory mechanism in ducks. A total of 280 one-day-old specific pathogen-free male ducklings (Anas platyrhynchos) with an average body weight of 35 ± 1 g were randomly divided into two dietary treatment groups with different supplementation levels of resveratrol for growth performance experiments: R0 and R400 (0 and, 400 mg kg−1 resveratrol, respectively). At the age of 28 days, 16 ducks were selected from each treatment group and divided into four subgroups for a 2 × 2 factorial pathological experiment: R0; R400; R0 + LPS; R400 + LPS, (0 mg kg−1 resveratrol, 400 mg kg−1 resveratrol, 0 mg kg−1 resveratrol, 400 mg kg−1 resveratrol + 5 mg lipopolysaccharide/kg body weight). The results showed that resveratrol significantly improved final body weight and average daily gain (p < 0.01) and alleviated the lipopolysaccharide-induced inflammatory response with a reduction in IL-1β and IL-6 in the plasma and the liver (p < 0.05). Resveratrol improved mRNA levels of Nrf2 and HO-1 and decreased the mRNA levels of TLR4 and NF-κB in duck liver (p < 0.05). Dietary resveratrol can improve growth performance and reduce inflammation through the Nrf2/HO-1 and TLR4/NF-κB signaling pathways in duck.

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