scholarly journals New insights into the role of chitosan oligosaccharide in enhancing growth performance, antioxidant capacity, immunity and intestinal development of weaned pigs

RSC Advances ◽  
2017 ◽  
Vol 7 (16) ◽  
pp. 9669-9679 ◽  
Author(s):  
Jin Wan ◽  
Fei Jiang ◽  
Qingsong Xu ◽  
Daiwen Chen ◽  
Bing Yu ◽  
...  

Chitosan oligosaccharide (COS), an oligomer ofd-glucosamine, is a vital growth stimulant in the pig industry.

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 55-55
Author(s):  
Jessica Jasper ◽  
Omarh Mendoza ◽  
Katie Brown ◽  
Caleb M Shull ◽  
Nicholas Gabler

Abstract Nutritional strategies to enhance intestinal development, caloric intake, and hydration are advantageous to newborn and weaned pigs by aiding in growth performance and survivability. However, the lifetime benefit of such strategies in commercial pigs has been poorly elucidated. Therefore, the objective of this study was to evaluate the effect of an isotonic electrolyte supplementation on lifetime pig performance. Three hundred ninety-three piglets (Duroc sires by Yorkshire-Landrace F1 females; 1.63 ± 0.38 kg birthweight) born from 40 sows were allotted to one of two treatments: 1) supplementation of TonistyPx (TON+) or 2) no supplementation of TonisityPx (CON). TON+ pigs were given a liquid solution from d 2 to 8 (500 mL/litter/d). All pigs were weaned and shipped to a wean-to-finish site, and randomly allotted by litter/supplemental treatment across two barns with identical configuration (12 pens/treatment; 15-17 pigs/pen). Once allocated, TON+ pens were given a liquid solution (5.68 L/pen/d) on the day of placement and a gruel solution on day 2 and 3 post placement. Individual pig BW was recorded at birth, weaning, end of nursery and end of finishing period. From birth to weaning CON pigs tended to have increased weaning BW compared to TON+ pigs (5.63 vs. 5.38, P < 0.10). At the end of the 42d nursery in which all pigs were fed the same common diets with supplementation from d 0 to 3 post-weaning, no differences in BW were reported between CON and TON+ pigs (25.62 vs. 25.43 kg, P >0.05). However, at the end of the grow-finish period the TON+ pigs were 4.63% heavier compared to CON pigs (P < 0.01). No numerical differences in mortality were reported in nursery or grow-finish periods. In summary, isotonic electrolyte supplementation to newborn and weaned pigs resulted in a 5.87 kg heavier BW at the end of the finisher period.


Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1427
Author(s):  
Chi Wang ◽  
Fei Zhao ◽  
Zhen Li ◽  
Xu Jin ◽  
Xingyong Chen ◽  
...  

The study investigated resveratrol’s effect on growth performance, intestinal development, and antioxidant capacity of broilers subjected to heat stress (HS). A total of 162 21-day-old male AA broilers were randomly divided into 3 treatment groups with 6 replicates of 9 birds each. The 3 treatment groups were as follows: the control (CON), in which broilers were housed at 22 ± 1 °C for 24 h day−1, and the HS and HS + resveratrol (400 mg/kg) groups, in which broilers were housed at 33 ± 1 °C for 10 h a day from 8:00 to 18:00 and 22 ± 1 °C for rest of the time. Results indicated that birds in the HS group exhibited lower (p < 0.05) final body weight (BW) and average daily gain (ADG) compared with birds in the CON group. HS birds also had lower (p < 0.05) relative jejunum weight, relative ileum and jejunum length, jejunal villus height, and villus height to crypt depth ratios than the CON group. The activities of glutathione peroxidase (GPX), glutathione S-transferase (GST), superoxide dismutase (SOD), and the mRNA levels of NF-E2-related factor 2 (Nrf2), SOD1, and GPX were also lower (p < 0.05) in the HS than CON group. The HS group had higher (p < 0.05) protein carbonyl (PC) contents and Kelch-like ECH-associated protein 1 (Keap1) mRNA levels. Compared with HS group, the HS + resveratrol group exhibited higher (p < 0.05) BW and ADG, relative jejunum weight, relative length of ileum, jejunal villus height, activities of GPX and GST, and mRNA levels of Nrf2 and SOD1, but they had lower (p < 0.05) PC content and Keap1 mRNA levels. In conclusion, resveratrol can improve the intestinal development and antioxidant function of broilers under HS, and therefore improve growth performance. The mechanism by which resveratrol enhances the intestinal antioxidant capacity is mediated by Nrf2 signaling pathway.


2021 ◽  
Vol 75 (2) ◽  
pp. 121-136
Author(s):  
Gang Zhang ◽  
Jinbiao Zhao ◽  
Wenxuan Dong ◽  
Xiaoming Song ◽  
Jianjun Zang ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Lixue Wang ◽  
Ying Zhang ◽  
Ling Liu ◽  
Fei Huang ◽  
Bing Dong

Tea tree oil (TTO) exerts key roles in improving growth performance of pigs. However, knowledge is limited regarding comparative effects of Encp TTO and Un-encp TTO supplementation on growth performance of pigs. A study determined the effects of TTO or its capsulation on growth performance, antioxidant capacity, and intestinal microbiome of weaned pigs. A total of 144 healthy pigs (8.5 ± 0.24 kg) were subjected to four treatments for a 28-d trial with six replicates per treatment and six pigs per pen: negative control, NC; positive control, PC (antibiotic supplemented); Un-encp TTO (supplemented with unencapsulated TTO); Encp TTO (supplemented with encapsulated TTO). NC, TTO, and PC treatments were compared with regard to improved average daily gain (ADG), average daily feed intake (ADFI), feed conversion rate, nutrient digestibility, and intestinal morphology (p &lt; 0.05) and decreased diarrhea rate. TTO- and PC-treated pigs had higher levels of serum superoxide dismutase, glutathione peroxidase, and immunoglobulin G; lower levels of liver aspartate aminotransferase and alanine aminotransferase; and improved concentrations of interleukin 10 (IL-10), tumor necrosis factor α, and IL-1β (p &lt; 0.05). TTO- and PC-treated pigs had higher abundance of beneficial bacterial species Subdoligranulum and lower abundance of diarrhea associated species Escherichia–Shigella in cecal and colonic digesta (p &lt; 0.05). Encapsulation of TTO preserved more activities of TTO than its unencapsulated counterpart by showing higher ADG, ADFI, and feed conversion rate during day 1 (d1) to d14 (p &lt; 0.05) and tended to lower diarrhea rate (p = 0.083) and improve villous height/crypt depth (VH/CD) ratio (p = 0.089) in jejunum. Encapsulation of TTO also improved antioxidant indexes and decreased liver injury and inflammation accordingly (p &lt; 0.05). Encapsulated TTO-treated pigs had higher abundance of beneficial Clostridium_sensu_stricto_1 and lower the abundance of harmful Escherichia–Shigella in cecal and colonic digesta (p &lt; 0.05). Our results demonstrated TTO benefits on improving growth performance of weaned pigs and further proved that encapsulation of TTO was superior to its unencapsulated counterpart at multiples. Encapsulated TTO was similar to the PC group and could be potentially an alternative of feed antibiotics for weaned pigs.


Author(s):  
Jiali Chen ◽  
Fuchang Li ◽  
Weiren Yang ◽  
Shuzhen Jiang ◽  
Yang Li

Exogenous CAT derived from microorganisms has been widely used in food, medicine, and other industries. Recent study also found that exogenous CAT supplementation could improve growth performance and antioxidant capacity of weaned pigs.


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