scholarly journals Administering an Appeasing Substance to Gir × Holstein Female Dairy Calves on Pre-Weaning Performance and Disease Incidence

Animals ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 1961
Author(s):  
Beatriz Angeli ◽  
Bruno Cappellozza ◽  
José Luiz Moraes Vasconcelos ◽  
Reinaldo Fernandes Cooke
Keyword(s):  
Disease Incidence ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Physical Contact ◽  
Dairy Calves ◽  
Pharmacological Intervention ◽  
Experimental Unit ◽  
Skin Area ◽  
Pharmacological Interventions ◽  
Improved Performance

(1) Background: Ruminants often face stressful situations throughout their productive lives. More specifically, pre-weaning dairy calves are exposed to novel environments, feedstuffs, and pathogens that affect their health and performance. Hence, alternatives that reduce stress and promote growth of pre-weaning dairy calves are warranted. Therefore, this study evaluated the effects of biweekly bovine appeasing substance (BAS) administration on performance and disease incidence in dairy Gir × Holstein female calves prior to weaning. (2) Methods: At birth, 140 female Gir × Holstein calves were randomly assigned to receive BAS (SecureCattle; (IRSEA Group, Quartier Salignan, France; n = 70) or placebo (BAS carrier, diethylene glycol monoethyl ether; CON; n = 70) biweekly until weaning (70 days of age). Calves were allocated into individual housing at random, with no physical contact between treatments to avoid cross-contamination. Experimental treatments (5 mL) were applied topically to the nuchal skin area of each calf. Throughout the experimental period, all animals were observed daily for medical conditions (diarrhea, pneumonia, and others), medical/pharmacological interventions were recorded, and the costs related to these procedures were analyzed. Concurrently with treatment application, calves were individually weighed, and data were analyzed using animal as the experimental unit. (3) Results: Treatment × day and treatment × period (14-day interval) interactions were observed for body weight (BW) and average daily gain (ADG; p ≤ 0.05), respectively. Calves receiving BAS had greater BW at weaning (p = 0.02) and tended to have a greater BW on day 56 (p = 0.06). Similarly, ADG was greater for BAS from days 42 to 56 (p = 0.04) and tended to be greater from days 56 to weaning (p = 0.10). No differences were observed on the overall occurrence of diseases (p = 0.92), whereas the most common observed diseases were diarrhea and pneumonia. The incidence and mean age at which animals were detected with these diseases did not differ (p ≥ 0.46). Nonetheless, CON calves detected with disease had a reduced ADG vs. BAS-administered counterparts (p < 0.01). No differences were observed between disease-diagnosed BAS vs. healthy CON, but healthy BAS had a greater ADG vs. healthy CON (p = 0.03). A treatment effect was observed for the cost per head of each pharmacological intervention (p = 0.05). (4) Conclusions: In summary, BAS administration at a 14-day interval improved performance and reduced the costs of pharmacological interventions of pre-weaning Gir × Holstein dairy calves.

scholarly journals 5 Evaluating Finishing Performance of Cattle Fed HMC:SFC Blends with Modified Distillers Grains

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 127-128
Author(s):  
Braden Troyer ◽  
Zac Carlson ◽  
Levi J McPhillips ◽  
Andrea K Watson ◽  
James C MacDonald ◽  
...  
Keyword(s):  
Average Daily Gain ◽  
Distillers Grains ◽  
Experimental Unit ◽  
Marbling Score ◽  
Finishing Cattle ◽  
Finishing Diets ◽  
Randomized Design ◽  
Gate System ◽  
Improved Performance ◽  
Extension Center

Abstract Steam-flaked corn (SFC) has been widely used in feedlots in the southern United States to improve feed efficiency (G:F) by increasing starch digestibility. Similarly, feedlots in the Midwest have commonly fed high moisture corn (HMC), both to ensure corn supply for the year and to improve G:F. However, popularity of SFC in the Midwest is on the rise, but producers still recognize the benefits of HMC utilization. A study was conducted at the Eastern Nebraska Research and Extension Center (ENREC) to compare finishing cattle performance when fed HMC, SFC, or a blend. The objective was to determine the optimum inclusion of the grains when modified distillers grains (MDGS) was included at 20% of the diet. This study utilized 90 yearling steers (353 kg; SD=5.8 kg) individually fed using the Calan gate system in a completely randomized design with cattle stratified by body weight (BW). Treatments included: 100% HMC, 75% HMC blended with 25% SFC, a 50% blend of the grains, 25% HMC blended with 75% SFC, or 100% SFC (DM basis; % of the 70% grain in the diet). Cattle were on feed 168 days with 3-day initial BW and 1 day final BW. Animal was the experimental unit with 18 replications per treatment. No differences in initial BW, ribeye area, or marbling score between treatments were detected (P &gt; 0.12). Ending BW, hot carcass weight, average daily gain, and G:F all linearly increased with increasing inclusion of SFC in the diet (P &lt; 0.05). Carcass adjusted G:F improved from 0.158 to 0.170 for 100% HMC compared to 100% SFC diets, respectively. In conclusion, feeding higher inclusions of SFC in finishing diets resulted in improved performance compared to HMC in diets containing 20% MDGS.

Evaluation of ketogenic vs. glucogenic substrates as energy sources in starter diets for Holstein dairy calves

2014 ◽  
Vol 94 (4) ◽  
pp. 717-723 ◽  
Author(s):  
H. Beiranvand ◽  
M. Khorvash ◽  
G. R. Ghorbani ◽  
A. Homayouni ◽  
L. Bachmann ◽  
...  
Keyword(s):  
Volatile Fatty Acids ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Dairy Calves ◽  
Energy Sources ◽  
Sodium Propionate ◽  
Waste Milk ◽  
Weaning Age ◽  
Calf Performance ◽  
Holstein Calves

Beiranvand, H., Khorvash, M., Ghorbani, G. R., Homayouni, A., Bachmann, L. and Kargar, S. 2014. Evaluation of ketogenic vs. glucogenic substrates as energy sources in starter diets for Holstein dairy calves. Can. J. Anim. Sci. 94: 717–723. The objective of this study was to investigate the influence of the inclusion of granular sugar and sodium propionate as ketogenic and glucogenic substrates, respectively, in calf starter diets on the performance, weaning age, rumen fermentation characteristics and plasma β-hydroxybutyrate (βHBA). Twenty-one newborn male Holstein calves were housed in individual pens until 10 wk of age, receiving starter ad libitum, fresh water free choice, and fed four liters of pasteurized waste milk daily until weaning. Calves were randomly assigned to one of the following treatments: (1) no supplemental additive (Control); (2) granular sugar (5% of dietary DM; Sugar); and (3) sodium propionate (5% of dietary DM; Propionate). Overall, no differences were observed among treatments for starter intake, average daily gain, feed efficiency, day of weaning, body weight at weaning and at the end of the study. Body measurements including body length, hip height, hip width, and heart girth were remained unchanged among treatments. Ruminal fluid pH (5.36 to 5.58) and concentrations of total volatile fatty acids (93.1 to 101.6 mM), acetate (43.6 to 53.1 mM), propionate (30.5 to 35.1 mM), and ratio of acetate to propionate (1.42 to 1.89) were not affected by treatments over the experimental period. However, the concentration of butyrate was greater at 35 and 70 d of age in calves receiving Sugar compared with calves receiving Propionate, but not compared with the Control. Greater blood βHBA at 45, 60 and 70 d of age was noticed in calves fed Sugar compared with those fed Control and Propionate. In conclusion, according to the concentrations of supplemental ketogenic and glucogenic substrates used in the current experiment, sugar and sodium propionate in starter diets did not improve calf performance.

scholarly journals Administering an appeasing substance to beef calves at weaning to optimize productive and health responses during a 42-d preconditioning program

2020 ◽  
Vol 98 (9) ◽  
Author(s):  
Kelsey M Schubach ◽  
Reinaldo F Cooke ◽  
Courtney L Daigle ◽  
Alice P Brandão ◽  
Bruna Rett ◽  
...  
Keyword(s):  
Average Daily Gain ◽  
Plasma Concentrations ◽  
Experimental Unit ◽  
Skin Area ◽  
Beef Calves ◽  
Exit Velocity ◽  
Diarrhea Virus ◽  
Management Scheme ◽  
Hair Samples ◽  
And Performance

Abstract This experiment evaluated the impacts of administering a bovine appeasing substance (BAS) to beef calves at weaning on their performance, physiological responses, and behavior during a 42-d preconditioning program. Eighty calves (40 heifers and 40 steers; 90% British × 10% Nellore) were weaned at 233 ± 2 d of age (day 0); ranked by sex, weaning age, and body weight (BW); and assigned to receive BAS (IRSEA Group, Quartier Salignan, France; n = 40) or placebo (diethylene glycol monoethyl ether; CON; n = 40). Treatments (5 mL) were topically applied to the nuchal skin area of each animal following dam separation. Within treatment, calves were allocated to one of eight drylot pens (four pens per treatment; pen being the experimental unit) and received a free-choice total mixed ration (TMR) from day 0 to 42, intake of which was assessed daily. Live behavior observations were conducted on days 1, 2, 4, 8, 16, and 32. Temperament was assessed and blood samples were collected via jugular venipuncture on days −21, 0, 3, 7, 14, 28, and 42. Hair samples were collected from the tail switch on days 0, 14, 28, and 42. Calves were vaccinated against bovine respiratory disease viruses on days −21 and 0. Average daily gain from day 0 to 42 did not differ between treatments (P = 0.57) but was greater (P = 0.05) in BAS vs. CON calves from day 0 to 28. Intake of TMR was greater (P = 0.05) during the first week for BAS vs. CON calves (treatment × week; P = 0.08). The mean proportion of calves feeding simultaneously and performance of social and play behaviors were greater (P ≤ 0.05) for BAS vs. CON calves. Escape attempts were greater (P &lt; 0.01) for BAS vs. CON calves on day 1 (treatment × day; P = 0.03). Exit velocity was greater (P = 0.04) for CON vs. BAS calves on day 14 and tended (P = 0.10) to be greater for CON vs. BAS calves on day 7 (treatment × day; P = 0.03). Mean plasma concentrations of haptoglobin were greater (P = 0.02) in CON vs. BAS calves. Hair cortisol concentrations were greater (P = 0.05) in CON vs. BAS calves on day 14 (treatment × day; P = 0.03). Mean serum concentrations of antibodies against bovine viral diarrhea virus were greater (P = 0.02) in BAS vs. CON calves. Collectively, BAS administration to beef calves at weaning alleviated stress-induced physiological reactions, improved temperament evaluated via chute exit velocity, enhanced humoral immunity acquired from vaccination, and appeared to have accelerated adaptation to novel management scheme and environment.

216 Effect of Dietary L-valine Supplementation on Growth Performance, Immune Response, and Microbial Metabolites in Weaned Pigs Raised in Varying Sanitary Conditions

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 113-114
Author(s):  
Bonjin Koo ◽  
Martin Nyachoti
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Average Daily Gain ◽  
Basal Diet ◽  
Experimental Period ◽  
Experimental Unit ◽  
Microbial Metabolites ◽  
Weaned Pigs ◽  
Sanitary Condition ◽  
Sanitary Conditions

Abstract This study investigated the effects of dietary L-valine supplementation and sanitary conditions on growth performance, immune response, and microbial metabolites in weaned pigs. Thirty-two weaned pigs (6.98 ± 0.47 kg) were randomly assigned to treatments in a 2 × 2 factorial arrangement based on dietary Val level and sanitary condition (clean or unclean). The pigs were fed either a basal diet containing the standard levels of Val suggested by NRC (2012) or the basal diet with an additional 0.1% of L-Val. A room designated as the clean room was washed weekly, whereas the designated unclean room was not washed throughout the experiment and 5 kg of manure from the nursery pig barn was spread on the pen floors on day 1. All data were analyzed using a mixed procedure of SAS, with the individual pen as the experimental unit. The pigs raised in unsanitary conditions exhibited a lower average daily gain and average daily feed intake and a higher incidence of diarrhea than those raised in sanitary conditions during the 14-day experimental period (P &lt; 0.05). The pigs in the unclean group also had a lower concentration of butyrate in the jejunum and a higher concentration of ammonia-N in the colon than those in the clean group (P &lt; 0.05). Dietary valine supplementation reduced plasma interleukin (IL)-1α and IL-1 receptor antagonist concentrations as well as isovalerate and ammonia-N concentrations in the colon (P &lt; 0.05). Interactions between dietary Val supplementation and sanitary conditions were observed in the abundance of mRNA-encoding β-defensins 113, 125, and 129 (P &lt; 0.05). In conclusion, dietary Val supplementation beneficially modulates inflammatory response and microbial metabolites regardless of sanitary condition, while transcriptional levels of β-defensins are regulated by dietary Val supplementation in a manner dependent on housing hygiene conditions.

scholarly journals Effects of switching from corn distillers dried grains with solubles- to corn- and soybean meal-based diets on finishing pig performance, carcass characteristics, and carcass fatty acid composition

2020 ◽  
Vol 4 (2) ◽  
pp. 715-723
Author(s):  
Annie B Lerner ◽  
Mike D Tokach ◽  
Joel M DeRouchey ◽  
Steve S Dritz ◽  
Robert D Goodband ◽  
...  
Keyword(s):  
Soybean Meal ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Experimental Unit ◽  
Net Energy ◽  
Finishing Pigs ◽  
Withdrawal Period ◽  
Carcass Yield ◽  
Distillers Dried Grains ◽  
Corn Distillers

Abstract Corn distillers dried grains with solubles (DDGS) are known to negatively impact carcass yield and fat quality, thus finishing pigs may need to be switched from diets containing DDGS to corn–soybean meal (CSBM) diets before marketing (DDGS withdrawal). A total of 860 finishing pigs (PIC C48 or L42 × 327; initially 66.2 kg body weight, BW) were used in a 76-day experiment to evaluate the effects of DDGS withdrawal periods at increasing intervals before harvest. Pen served as the experimental unit, and there were seven replicate pens per treatment with 23 to 25 pigs per pen. Pens were blocked by BW and allotted to one of five dietary treatments differentiated by the DDGS withdrawal period: 76, 42, 27, 15, or 0 day before harvest. Diets contained 40% DDGS from 22 to 66 kg prior to the experiment, 0% or 35% DDGS during the experiment from ~66 to 82 kg, and 0% or 30% DDGS until the completion of the trial. Diets were not balanced for net energy. Linear and quadratic response to time following dietary switch was evaluated using PROC GLIMMIX. For the overall period (day 76 prior to market to day 0), as withdrawal period increased, average daily gain (ADG) and final BW increased (linear, P &lt; 0.002) and feed efficiency (G:F) improved (quadratic, P = 0.019). Average daily feed intake increased (quadratic, P = 0.030) as withdrawal period increased. There was an increase (linear P = 0.010) in hot carcass weight (HCW), with a marginally significant increase in carcass yield (linear, P = 0.094) with increasing withdrawal period. Loin depth and lean percentage did not demonstrate any evidence for treatment differences (P &gt; 0.132). Backfat increased (linear, P = 0.030) with increasing withdrawal period. Finally, iodine value (IV) of belly fat was decreased (linear, P = 0.001) with increased withdrawal period. In conclusion, switching from a DDGS-based diet to a CSBM-based diet for longer periods before slaughter increased ADG and improved G:F, resulting in increased HCW. After diets were switched from DDGS to CSBM, pigs demonstrated an increase in intake, likely due to the ability to consume high volumes of feed after consuming high fiber (DDGS) diets. Belly fat IV was decreased as the length of time after dietary change was increased, with the lowest IV resulting from pigs that consumed CSBM for the entire experimental period.

scholarly journals Effects of Bulk Tank Milk, Waste Milk, and Pasteurized Waste Milk on the Intake, Ruminal Parameters, Blood Parameters, Health, and Performance of Dairy Calves

Animals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3552
Author(s):  
Sabrina de Freitas Vieira ◽  
Sandra Gesteira Coelho ◽  
Hilton do Carmo Diniz Neto ◽  
Hemily Cristina Menezes de Sá ◽  
Barbara Pironi Pereira ◽  
...  
Keyword(s):  
Rumen Fluid ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Blood Parameters ◽  
Dairy Calves ◽  
Bulk Tank Milk ◽  
Significant Difference ◽  
Waste Milk ◽  
Bulk Tank ◽  
And Performance

The aim of this study was to evaluate the effects of bulk tank milk (BTM), WM, and PWM on the intake, ruminal parameters, blood parameters, health, and performance of dairy calves. Forty-five male crossbred dairy calves (Gyr × Holstein) were used. On their fourth day of age, animals were grouped according to body weight, serum protein levels, and genetic composition. Three treatments were assessed: BTM (n = 15), WM from cows in antibiotic treatment (n = 15), and PWM via high-temperature, short-time pasteurization (72–74 °C for 16 s) (n = 15). During the experimental period (from 4 to 60 d of age), animals were fed 6 L of milk/d, divided into two equal meals. Water and concentrate were provided ad libitum. Daily measurements were made for milk, concentrate, and water intakes, as well as for fecal and respiratory scores. Rumen fluid and blood were sampled weekly. The following parameters were evaluated: volatile fatty acids (VFAs), pH and ammonia-N in rumen fluid, and β-hydroxybutyrate (BHB) and glucose in blood. Animals were weighed at birth, 4 d of age, and weekly up to 60 d of age. At the end of the experimental period (60 ± 1 d), all animals were euthanized for pulmonary evaluation. The randomized complete design with an interaction between treatment and week was the experimental method of choice for testing the hypothesis of the treatment’s effect on all evaluated outcomes. Animals in the BTM treatment had higher milk dry matter intake (DMI), followed by WM and PWM calves. Concentrate DMI was lower for BTM in comparison to WM and PWM calves. However, total DMI showed no significant differences between treatments. The rumen fluid from calves receiving PWM had higher concentrations of acetate and propionate than that of BTM and WM animals. No differences were observed between treatments for blood glucose and BHB concentrations. Health parameters (fecal and respiratory scores) and pneumonia occurrence showed no significant difference between treatments. No differences were observed for average daily gain (ADG) or body growth. Feeding WM and PWM did not show significant negative effects on the intake, ruminal parameters, blood parameters, health, or performance of dairy calves.

scholarly journals Effects of a dietary added formaldehyde-propionic acid blend on feed enterobacteria counts and on growing pig performance and fecal formaldehyde excretion

2014 ◽  
Vol 45 (3) ◽  
pp. 474-479 ◽  
Author(s):  
Maicon Sbardella ◽  
Danilo do Prado Perina ◽  
Carla de Andrade ◽  
Flavio Alves Longo ◽  
Valdomiro Shigueru Miyada
Keyword(s):  
Propionic Acid ◽  
Block Design ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Experimental Unit ◽  
Design Experiment ◽  
Growing Pig ◽  
Randomized Complete Block Design ◽  
Pig Performance ◽  
Daily Gain

The purpose of this study was to evaluate the effects of a dietary added formaldehyde-propionic acid blend on feed enterobacteria counts and on growing pig performance and fecal formaldehyde excretion. Forty pigs (34.2±1.8kg BW) were used in a randomized complete block design experiment with four treatments, five replications per treatment and two animals per experimental unit (pen). The treatments were: 0.0, 1.0, 2.0, and 3.0g of blend kg-1 of feed. No effects (P>0.05) of dietary added blend levels were observed on average daily gain, average daily feed intake and feed:gain ratio during 1 to 14 and 1 to 28 days of experiment. Increasing dietary levels of blend reduced quadratically (P<0.01) total Enterobacteriaceae counts on 1st and 14th day after feed mixing, allowing to estimate, respectively, 2.63 and 3.35g kg-1 (average 2.99g kg-1) as the formaldehyde-propionic acid blend levels with lowest feed Enterobacteriaceae counts. Therefore, formaldehyde-propionic acid blend can reduce and/or control feed Enterobacteriaceae growth. There was no effect (P>0.05) of blend on fecal formaldehyde excretion on the 28th day of the experimental period. Therefore, the addition of dietary formaldehyde-propionic acid blend up to 3.0g kg-1 of feed reduces the Enterobacteriaceae counts until the 14th day after feed mixing, without any effects on growing pig performance and fecal formaldehyde excretion

scholarly journals Evaluating dietary acidifiers as alternatives for conventional feed-based antibiotics in nursery pig diets

2021 ◽  
Author(s):  
Payton L Dahmer ◽  
Cassandra K Jones
Keyword(s):  
Block Design ◽  
Average Daily Gain ◽  
Random Effect ◽  
Dietary Treatment ◽  
Experimental Period ◽  
Blood Parameters ◽  
Negative Control ◽  
Experimental Unit ◽  
Randomized Block Design ◽  
Nursery Pig

Abstract A total of 360 weanling pigs (DNA 200 × 400; initially 9.7 ± 0.23 kg BW) were used in a 21-d experiment with 6 pigs/pen, 10 replicate pens/treatment, and 2 separate nursery rooms, each with 30 pens. Pigs were weighed and allotted to pens based on BW in a completely randomized block design to one of 6 treatment diets: 1) Negative control (no organic acids or antibiotics) and the control with 2) 0.25% Acidifier A; 3) 0.3% Acidifier B; 4) 0.5% Acidifier C); 5) 50 g/t Carbadox; 6) 400 g/t Chlortetracycline. Upon weaning, a common diet with no antibiotics or additives was fed for 21 d (phases 1 and 2; d -21 to d 0), followed by a 21 d experimental period (phase 3; d 0 to d 21) where treatment diets were fed. Pigs and feeders were individually weighed on a weekly basis to calculate average daily gain (ADG), average daily feed intake (ADFI) and feed efficiency (G:F). Data were analyzed using the PROC GLIMMIX procedure of SAS (v 9.4, SAS Inst., Cary, NC) with pen as the experimental unit, treatment as a fixed effect and room as a random effect. Dietary treatment had a significant impact (P &lt; 0.05) on ADG, ADFI and G:F each week and for the overall experimental period (d 0 to 21). Specifically, from d 0 to 7, pigs fed CTC had increased (P = 0.001) ADG compared to those fed Acidifier B, Acidifier C and Carbadox, while pigs fed the negative control and Acidifier A diets were intermediate. Additionally, pigs fed the CTC diet had improved (P = 0.0002) ADFI when compared to all other treatments. From d 7 to 14 and d 14 to 21, pigs fed the Carbadox diet had decreased (P &lt; 0.0001) ADG compared to all other treatments. During the overall period (d 0 to 21), pigs fed diets containing Carbadox had reduced ADG and ADFI (P &lt; 0.0001), while pigs fed CTC had improved (P &lt; 0.0001) ADG compared to all other treatments. Additionally, blood parameters, fecal consistency and fecal microbial populations were analyzed on a subset of pigs (n = 5 pigs/treatment). Dietary treatment significantly impacted (P &lt; 0.05) concentrations of protein, globulin, phosphorus, alkaline phosphatase, and sorbitol dehydrogenase in the blood. Treatment also significantly impacted (P = 0.0005) fecal score but did not affect (P = 0.59) fecal microbial growth from d 0 to 21. In summary, CTC continues to be a valuable additive to improve performance in the nursery. Further investigation surrounding the efficacy of dietary acidifiers as antibiotic alternatives is warranted given inconclusive evidence in this study.

scholarly journals Effects of increasing dietary zinc on growth performance and carcass characteristics of pigs raised under commercial conditions1,2

2019 ◽  
Vol 3 (2) ◽  
pp. 731-736 ◽  
Author(s):  
Henrique S Cemin ◽  
Jason C Woodworth ◽  
Mike D Tokach ◽  
Steve S Dritz ◽  
Joel M DeRouchey ◽  
...  
Keyword(s):  
Growth Performance ◽  
Removal Rate ◽  
Block Design ◽  
Average Daily Gain ◽  
Random Effect ◽  
Carcass Characteristics ◽  
Experimental Period ◽  
Feed Ratio ◽  
Experimental Unit ◽  
Final Body Weight

Abstract A total of 2,430 pigs (PIC 337 × 1050; Hendersonville, TN; initially 30.1 kg) were used in a 113-d growth trial to determine the effects of increasing dietary Zn on growth performance and carcass characteristics of finishing pigs raised under commercial conditions. Pens of pigs were assigned to be fed one of five dietary treatments in a randomized complete block design. Treatments consisted of 50, 87.5, 125, 162.5, or 200 mg/kg added Zn from Zn hydroxychloride (IntelliBond Z, Micronutrients, Indianapolis, IN). Two identical barns were used for a total of 18 pens per treatment with 27 pigs per pen. Experimental diets were fed in five phases and contained a vitamin-trace mineral premix without added Zn. Pens of pigs were weighed approximately every 2 wk to calculate average daily gain (ADG), average daily feed intake (ADFI), and gain-to-feed ratio (G:F). At the end of the experimental period, pigs were tattooed with a pen identification number and transported to a packing plant to measure hot carcass weight (HCW), backfat, loin depth, and calculated lean percentage. Data were analyzed block nested within barn as a random effect and pen as the experimental unit. From days 0 to 42, pigs fed diets with increasing added Zn had lower (linear, P = 0.043) ADFI and a tendency (P = 0.092) for lower ADG. From days 42 to 113, increasing added Zn resulted in a quadratic response (P = 0.042) for ADFI and a tendency (linear, P = 0.056) for improved G:F. Overall (days 0 to 113), there were tendencies for quadratic responses for ADFI (P = 0.073) and G:F (P = 0.059), with the greatest G:F observed when 125 mg/kg of Zn was fed. Increasing added Zn resulted in a linear increase (P &lt; 0.001) in daily Zn intake. There were no differences (P &gt; 0.10) in overall ADG, final body weight, HCW, backfat, loin depth, lean percentage, mortality, and removal rate. In conclusion, there were no improvements in ADG when feeding beyond 50 mg/kg added Zn; however, providing 125 mg/kg added Zn resulted in the greatest G:F.

scholarly journals Supplementation with sodium butyrate improves growth and antioxidant function in dairy calves before weaning

2020 ◽  
Author(s):  
Wenhui Liu ◽  
A La Teng Zhu La ◽  
Alexander Evans ◽  
Shengtao Gao ◽  
Zhongtang Yu ◽  
...  
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Sodium Butyrate ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Immunoglobulin M ◽  
Dairy Calves ◽  
Milk Replacer ◽  
Control Group ◽  
Antioxidant Function

Abstract Background: There is increasing research interest in using short-chain fatty acids (SCFAs) including butyrate as potential alternatives to antibiotic growth promoters in animal production. This study was conducted to evaluate the effects of supplementation of sodium butyrate (SB) in liquid feeds (milk, milk replacer, and the mixture of both) on the growth performance, rumen fermentation, and serum antioxidant capacity and immunoglobins in dairy calves before weaning. Forty healthy female Holstein calves (4-day-old, 40 ± 5 kg of body weight) were housed in individual hutches and randomly allocated to 1 of 4 treatment groups (n = 10 per group) using the RAND function in Excel. The control group was fed no SB (SB0), while the other three groups were supplemented with 15 (SB15), 30 (SB30), or 45 (SB45) g per day of SB mixed into liquid feeds offered. The calves were initially fed milk only (days 2 to 20), then a mixture of milk and milk replacer (days 21 to 23), and finally milk replacer only (days 24 to 60).Results: The SB supplementation enhanced growth and improved feed conversion into body weight gain compared with the SB0 group，and the average daily gain increased quadratically with increasing SB supplementation. No significant effect on rumen pH; concentrations of NH3-N, individual and total VFAs; or acetate: propionate (A:P) ratio was found during the whole experimental period. Serum glutathione peroxidase activity increased linearly with the increased SB supplementation, while the serum concentration of maleic dialdehyde linearly decreased. Serum concentrations of immunoglobulin A, immunoglobulin G, or immunoglobulin M were not affected by the SB supplementation during the whole experimental period. Conclusions: Under the conditions of this study, SB supplementation improved growth performance and antioxidant function in pre-weaned dairy calves. We recommended 45 g per day as the optimal level of SB supplementation mixed into liquid feeds (milk or milk replacer) to improve the growth and antioxidant function of dairy calves before weaning.

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