scholarly journals Maternal Exposure to T-2 Toxin Affects Puberty Genes and Delays Estrus Cycle in Mice Offspring

Animals ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 471
Author(s):  
Aneela Perveen ◽  
Jiakun Shen ◽  
Niaz Ali Kaka ◽  
Chunmei Li
Keyword(s):  
Maternal Diet ◽  
Delayed Puberty ◽  
Control Group ◽  
Estrus Cycle ◽  
Postnatal Exposure ◽  
Female Mice ◽  
Weaning Age ◽  
Ovarian Damage ◽  
And Control ◽  
Level Analysis

Among foodborne toxicities, the T-2 toxin is the most toxic member of trichothecenes mycotoxins, which has been shown to impair the development and reproductive efficiency of animals. Pups are particularly more quickly prone to programming the effects of the maternal diet during the gestational and lactation periods. Few studies have reported the maternal toxic effect on the next generation. Dams were served the T-2 toxin at a dose of 0.005 and 0.05 mg/kg body weight/day and control group 0 mg/kg from gestation day 14 to lactation day 21. Female mice offspring were selected at the weaning age. Our observations indicate that age during the vaginal opening and di-estrus stage increased and the length of the estrus cycle, first di-estrus, and regular estrus cycling were delayed with prolonged di-estrus in the 0.05 mg/kg group compared to the 0.005 mg/kg and control group. Transcription level analysis showed that mice at a dose of 0.05 mg/kg exhibited a decrease in hypothalamic mRNA expression of Gnrh and Gnrhr, Lhb, and Fshb in the pituitary gland, with a significant decrease of Fshr and Lhr in the ovaries. Present findings report that postnatal exposure to the T-2 toxin delayed puberty age in female mice and induced oxidative stress, ovarian damage, and reduced vaginal epithelium wall majorly in the 0.05 mg/kg group, and showed fewer effects in the 0.005 mg/kg group.

Adventure Camp Programs, Self-Concept, and Their Effects on Behavioral Problem Adolescents

2007 ◽  
Vol 29 (3) ◽  
pp. 313-330 ◽  
Author(s):  
Bruce A. Larson
Keyword(s):  
Behavioral Problems ◽  
Behavioral Problem ◽  
Self Concept ◽  
Female Adolescents ◽  
Group Differences ◽  
Control Group ◽  
Control Groups ◽  
Significant Difference ◽  
And Control ◽  
Level Analysis

The purpose of this study was to examine the effects of an adventure camp program on the self-concept of adolescents with behavioral problems. Subjects in the study included 61 randomly selected male and female adolescents ranging in age from 9 to 17 years with behavioral problems. The treatment group of 31 adolescents was randomly selected from a population (N = 85) of behavioral problem adolescents who voluntarily attended an adventure camp. The control group of 30 adolescents was randomly selected from a population (N = 80) that underwent treatment for behavioral problems. Analysis of variance was utilized to determine if significant differences existed between the treatment and control groups. The paired t test was utilized to determine within group differences between pretest and posttest scores on both groups. Alpha for both tests was set at the .05 level. Analysis demonstrated a significant difference between the experimental and control 9- to 11-year-old age group's self-concept.

scholarly journals The effect of albumen removal before incubation (embryonic protein under-nutrition) on the post-hatch performance, regulators of protein translation activation and proteolysis in neonatal broilers

2012 ◽  
Vol 110 (2) ◽  
pp. 265-274 ◽  
Author(s):  
Nadia Everaert ◽  
Sonia Métayer-Coustard ◽  
Hilke Willemsen ◽  
Haitang Han ◽  
Zhigang Song ◽  
...  
Keyword(s):  
Maternal Diet ◽  
Ring Finger ◽  
Weight Ratio ◽  
Protein Translation ◽  
Control Group ◽  
Translational Efficiency ◽  
Under Nutrition ◽  
Altered Protein ◽  
Regulated Expression ◽  
And Control

Albumen was removed from broiler eggs before the start of incubation to induce prenatal protein under-nutrition in chicken embryos. With this method, the direct effect of protein deficiency was investigated, differing from mammalian models manipulating the maternal diet where indirect, hormonal effects can interfere. Based on the estimated albumen/egg weight ratio, 10 % of albumen was removed with an 18G needle, after making a hole at the sharp end of the egg with another 18G needle. Eggs were taped thereafter. The sham group underwent the same procedure, except that no albumen was removed. Control eggs did not receive any treatment. The removal of albumen decreased both embryonic and post-hatch body weight up to day 7 compared with the control group. On embryonic day 18, embryos from the albumen-deprived group had higher plasma uric acid levels compared with the sham (P= 0·016) and control (P= 0·009) groups. Moreover, a lower plasma amino acid concentration was observed at hatch compared with the sham (P= 0·038) and control (P= 0·152) groups. These findings indicate an altered protein metabolism. At hatch, a higher mRNA expression of muscle ring finger-1 (MuRF1), a gene related to proteolysis, was observed in albumen-deprived chicks compared with the control and sham chicks, together with an up-regulated expression of atrogin-1 (another atrogene) at this time point in the male protein-deficient chicks. These findings suggest that muscle proteolysis is transiently increased by the removal of albumen before the start of incubation. No evidence was found for altered protein synthesis capacity and translational efficiency in albumen-deprived chicks.

A Taenia crassiceps metacestode factor enhances ovarian follicle atresia and oocyte degeneration in female mice

2013 ◽  
Vol 89 (1) ◽  
pp. 49-57 ◽  
Author(s):  
S. Solano ◽  
N. Zepeda ◽  
N. Copitin ◽  
A.M. Fernandez ◽  
P. Tato ◽  
...  
Keyword(s):  
Ovarian Follicle ◽  
Light And Electron Microscopy ◽  
Terminal Deoxynucleotidyl Transferase ◽  
Control Group ◽  
Mouse Ovary ◽  
Taenia Crassiceps ◽  
Female Mice ◽  
Follicle Atresia ◽  
And Control ◽  
Histopathological Effects

AbstractThe histopathological effects of Taenia crassiceps infection or T. crassiceps metacestode factor inoculation on the mouse ovary were determined using six female mice in three groups: infected mice, mice inoculated with the metacestode factor and control mice. The control group was subcutaneously inoculated with healthy peritoneal fluid. The infected group was intraperitoneally inoculated with 40 T. crassiceps metacestodes, and the metacestode factor group was subcutaneously inoculated with T. crassiceps metacestode factor (MF). Light and electron microscopy and TUNEL (terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end labelling) assays revealed a significant increase in ovarian follicular atresia (predominantly in antral/preovulatory stages of development), oocyte degeneration (P< 0.05), and a decrease in the amount of corpus luteum in follicles of mice infected and inoculated with MF compared with the control group. Significant abnormalities of the granulosa cells and oocytes of the primordial, primary and secondary ovarian follicles occurred in both treated mouse groups (P< 0.05) compared with no degeneration in the control group. These pathological changes in female mice either infected with T. crassiceps metacestodes or inoculated with T. crassiceps MF may have consequences for ovulation and fertility.

The impact of pendular model on decision-making and tactical-technical performance of U18 male volleyball players

2021 ◽  
pp. 174795412110485
Author(s):  
Henrique de Oliveira Castro ◽  
Gibson M Praça ◽  
Isabel MR Mesquita ◽  
José Afonso ◽  
Gustavo De Conti Teixeira Costa ◽  
...  
Keyword(s):  
Decision Making ◽  
Control Group ◽  
Technical Performance ◽  
Significant Difference ◽  
Tactical Knowledge ◽  
And Control ◽  
The Impact ◽  
Experimental Group ◽  
Regular Training ◽  
Level Analysis

This study aimed to verify the influence of applying the Pendular Model of Tactical-Technical Training (Pendular Model) on decision-making and tactical-technical performance of U18 male volleyball athletes. A total of 44 U18 volleyball athletes participated in the study, divided into two groups: experimental group ( n = 23) and control group ( n = 21). The Declarative Tactical Knowledge Test in Volleyball was used for the decision-making analysis, while the Instrument for Technical-Tactical Performance Assessment in Volleyball was used for the specific tactical-technical performance components level analysis in the game. Experimental group athletes performed 24 training sessions using the Pendular Model, and control group athletes maintained 24 sessions of regular training. There was a significant difference in decision-making in the extremity attack and setting situations, being better in the experimental group than the control group in the pre and postintervention moments. There were significant differences in the adjustment, decision-making, and effectiveness components in athletes’ tactical-technical performance in game situations, being greater in the experimental group compared to the control group in the moments after 12 sessions and postintervention. It is concluded that the Pendular Model proved to be effective for improving decision-making in extremity attack and setting video situations and in the tactical-technical performance in the game in the adjustment, decision-making, and effectiveness components for male U18 volleyball athletes.

Conjugated Linoleic Acid Causes a Marked Increase in Liver α-Tocopherol and Liver α-Tocopherol Transfer Protein in C57BL/6 J Mice

2010 ◽  
Vol 80 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Pei-Min Chao ◽  
Wan-Hsuan Chen ◽  
Chun-Huei Liao ◽  
Huey-Mei Shaw
Keyword(s):  
Antioxidant Enzymes ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Thiobarbituric Acid ◽  
Control Group ◽  
Thiobarbituric Acid Reactive Substances ◽  
Control Groups ◽  
Protein Levels ◽  
Transfer Protein ◽  
And Control

Conjugated linoleic acid (CLA) is a collective term for the positional and geometric isomers of a conjugated diene of linoleic acid (C18:2, n-6). The aims of the present study were to evaluate whether levels of hepatic α-tocopherol, α-tocopherol transfer protein (α-TTP), and antioxidant enzymes in mice were affected by a CLA-supplemented diet. C57BL/6 J mice were divided into the CLA and control groups, which were fed, respectively, a 5 % fat diet with or without 1 g/100 g of CLA (1:1 mixture of cis-9, trans-11 and trans-10, cis-12) for four weeks. α-Tocopherol levels in plasma and liver were significantly higher in the CLA group than in the control group. Liver α-TTP levels were also significantly increased in the CLA group, the α-TTP/β-actin ratio being 2.5-fold higher than that in control mice (p<0.01). Thiobarbituric acid-reactive substances were significantly decreased in the CLA group (p<0.01). There were no significant differences between the two groups in levels of three antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase). The accumulation of liver α-tocopherol seen with the CLA diet can be attributed to the antioxidant potential of CLA and the ability of α-TTP induction. The lack of changes in antioxidant enzyme protein levels and the reduced lipid peroxidation in the liver of CLA mice are due to α-tocopherol accumulation.

TEACHING READING BY UTILIZING HOT POTATOES SOFTWARE TOWARD STUDENTS’ READING COMPREHENSION OF DESCRIPTIVE TEXT

2018 ◽  
Vol 5 (1) ◽  
pp. 26
Author(s):  
Abdullah Farih
Keyword(s):  
Reading Comprehension ◽  
Alternative Hypothesis ◽  
T Test ◽  
Control Group ◽  
Teaching Reading ◽  
Post Test ◽  
Quasi Experimental ◽  
Independent Variable ◽  
Level Of Significance ◽  
And Control

The objective of this study is to measure whether there is or not significant effect of teaching reading by utilizing Hot Potatoes software toward students’ reading comprehension of descriptive text. The variables used were the teaching treatment of Hot Potatoes Software as the independent variable and the students’ reading comprehension of Descriptive Text as dependent variable. Then, the research designed was Quasi-experimental design and the presentation of data used was quantitative. The data were obtained from the eleventh grade, of which 28 students were taken as sample. The students are divided into two groups; experiment group consisted of 12 students and control group consists of 16 students. To get the data, the pre-test and post-test were applied and then analyzed using t-test formula. The researcher had concluded that there is Significant effect of Hot Potatoes Software toward the students’ reading comprehension achievement. The result showed that mean of students’ post-test was increased. It is proved by the t-test (8.54) which is higher than t-table (2.05) at level of significance 5%. It means that the alternative hypothesis was accepted and it proved that Hot Potatoes Software had significant effect toward students’ reading comprehension of Descriptive Text

Perbandingan Efek Suplementasi Tablet Tambah Darah Dengan Dan Tanpa Vitamin C Terhadap Kadar Hemoglobin Pada Ibu Hamil Dengan Usiakehamilan 16-32 Minggu Di Desa Keniten Kecamatan Mojo Kabupaten Kediri

2017 ◽  
Vol 3 (1) ◽  
pp. 76
Author(s):  
Siti Asiyah ◽  
Dwi Estuning Rahayu ◽  
Wiranti Dwi Novita Isnaeni
Keyword(s):  
Treatment Group ◽  
Vitamin C ◽  
Gestational Age ◽  
Group Treatment ◽  
Sampling Technique ◽  
Hemoglobin Level ◽  
The Body ◽  
Control Group ◽  
Fetal Organ ◽  
And Control

The needed of Iron Tablet in pregnancy was increase than mother who not pregnant.  That  cause of  high metabolism at the pregnancy for formed of  fetal organ and energy. One of effort for prevent anemia in mother pregnant with giving the Iron tablet and vitamin c. The reason of  this research in 4 June – 11 July 2014 is for compare the effect of  iron tablet suplementation with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks In Desa Keniten Kecamatan Mojo Kabupaten Kediri. This research method using comparative analytical.  Research design type of Quasy Eksperiment that have treatment group and control group. Treatment group will giving by Iron tablet and 100 mg vitamin C, and control group just giving by iron tablet during 21 days. Population in this research are all of mother pregnant with Gestational Age Of 16-32 Weeks with Sampling technique is  cluster random sampling is 29 mother pregnant. Comparison analysis of  iron tablet suplementation effect with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks, data analysis using Mann Whitney U-test and the calculated U value (44,5) less than U-table (51). So there was difference of iron tablet suplementation effect with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks Therefore, the addition of vitamin C on iron intake is needed to increase the uptake of iron tablets. When the amount of iron uptake increases, the reserves of iron in the body will also increase, so as to prevent anemia in pregnant women; Keywords : Iron Tablet (Fe), Vitamin C, Hemoglobin level, Mother Pregnant

PENGARUH PENDEKATAN APTITUDE TREATMENT INTERACTION (ATI) TERHADAP PEMAHAMAN KONSEP MATEMATIKA SISWA KELAS VIII SMP NEGERI 25 PEKANBARU

2015 ◽  
Vol 4 (1) ◽  
pp. 79
Author(s):  
Herlina '
Keyword(s):  
Control Group ◽  
Treatment Interaction ◽  
Aptitude Treatment Interaction ◽  
Research Experiment ◽  
And Control

This research intent to see how big influence of approaching aptitude treatment interaction (ATI) to mathematics concept grasp student brazes VIII SMP Country 25 Pekanbaru. This research constitute my research experiment attention. Subjec in observational it is student braze VIII4 as agglomerate as experiment by totals student 40 person and VIII3'S classes as agglomerate as controls by totals students 40. Base analisis data to pretes's score to know student startup ability on agglomerate experiment and control group. On student experiment group that will study by ATI'S approaching has average early learned result mathematics (pretes) as big as 17,15. Meanwhile on group controls student who will study by ordinary learning (conventional) have average early learned result mathematics (pretes) as big as 13,85. Analisis is data to postes's score on agglomerate learned student experiment with ATI'S approaching has average final learned result mathematics (postes) as big as 74,63. Meanwhile on group controls learned student with ordinary learning (conventional) have average final learned result mathematics (postes) as big as 62,93. Of quiz result distinctive both of average usufruct to study mathematics finals (postes) that points out that there is difference which signifikan among both of experiment class with control class.Keywords: aptitude treatment interaction (ATI), mathematics concept

Non Emergency Calls-Depression Coupling in Call Handlers of Rescue 1122 Punjab, Pakistan

2019 ◽  
Vol 34 (Spring 2019) ◽  
pp. 43-55
Author(s):  
Syed Kamal Abid ◽  
Mujahid Hussain ◽  
Muhammad Raza ◽  
Rizwan-ul Haq ◽  
Rizwan Naseer ◽  
...  
Keyword(s):  
Occupational Stress ◽  
Independent Predictor ◽  
Depression Score ◽  
Demographic Variables ◽  
Workplace Stress ◽  
Control Group ◽  
Control Room ◽  
Emergency Calls ◽  
And Control ◽  
Evening Shift

The study was conducted to know whether bulk inflow of Non Emergency Calls (NECs) acts as an independent predictor for depression in call handlers of Rescue 1122, Punjab, Pakistan. Forty five (45) call handlers were recruited from evening shift of 9 districts. Similarly, same-sized control group was made out of field rescuers. The groups were compared for rate and severity level of depression using Beck’s Depression Inventory-II (BDI-II; Beck, Steer, & Brown, 1996). Probable predictors (except workplace stress) for depression in call handlers were evaluated through risk estimates. For workplace stress, a purposefully developed close- ended Workplace Stress Questionnaire including two subscales i.e. Non Emergency call and Control Room Environment of 30 items each was administrated. Twenty nine (64.4%) subjects of study group reported depression on BDI. Consequently, the same group had significantly higher mean depression score than control (18.2 vs. 12.6; p = .00). The scores also showed insignificant association with any of the probable predictors (demographic variables) of the call attendees. The respondents perceived more occupational stress against NECs. The findings attract the attention of authorities towards the severity of the concern.

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