scholarly journals The role of serum cystatin C as an early predictor for the diagnosis of chronic kidney disease in Mosul City

2019 ◽  
Vol 14 (1) ◽  
pp. 76-78
Author(s):  
Mohammed Khalid J. Al-Nori ◽  
Akram J. Ahmed
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Cystatin C ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
Early Predictor

scholarly journals Expressing the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) Cystatin C Equations for Estimating GFR With Standardized Serum Cystatin C Values

2011 ◽  
Vol 58 (4) ◽  
pp. 682-684 ◽  
Author(s):  
Lesley A. Inker ◽  
John Eckfeldt ◽  
Andrew S. Levey ◽  
Catherine Leiendecker-Foster ◽  
Gregory Rynders ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Cystatin C ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
Disease Epidemiology

scholarly journals Serum Cystatin C - Marker of Inflammation and Cardiovascular Morbidity in Chronic Kidney Disease Stages 1-4

2015 ◽  
Vol 27 (2) ◽  
pp. 75 ◽  
Author(s):  
Alma Muslimovic ◽  
Denijal Tulumovic ◽  
Senad Hasanspahic ◽  
Aida HamzicMehmedbasic ◽  
Ramajana Temimovic
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Cystatin C ◽  
Cardiovascular Morbidity ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
Disease Stages

scholarly journals Serum cystatin C levels are associated with coronary artery calcification in women without chronic kidney disease

2017 ◽  
Vol 70 (6) ◽  
pp. 559-564 ◽  
Author(s):  
Hiroyasu Sugiyama ◽  
Toru Miyoshi ◽  
Kazuhiro Osawa ◽  
Takashi Miki ◽  
Yuji Koide ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Coronary Artery ◽  
Kidney Disease ◽  
Cystatin C ◽  
Coronary Artery Calcification ◽  
Serum Cystatin C ◽  
Serum Cystatin

scholarly journals Comparison of Chronic Kidney Disease Epidemiology Collaboration Equations with Other Accepted Equations for Estimation of Glomerular Filtration Rate in Indian Chronic Kidney Disease Patients

2017 ◽  
Vol 16 (2) ◽  
pp. 238-244
Author(s):  
Kumaresan Ramanathan ◽  
Giri Padmanabhan
Keyword(s):  
Chronic Kidney Disease ◽  
Glomerular Filtration Rate ◽  
Kidney Disease ◽  
Serum Creatinine ◽  
Cystatin C ◽  
Filtration Rate ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
Disease Epidemiology ◽  
Measured Gfr

Background and Aim: In routine clinical practice, the estimation of glomerular filtration rate (GFR) based on serum creatinine has been followed. However, the reliability of creatinine in estimation of GFR is biased and imprecise, leading to the misdiagnosis of chronic kidney disease (CKD). The serum cystatin C is an alternative marker for estimating GFR. Hence, we aimed to compare the newly proposed Chronic Kidney Disease Epidemiology Collaboration Equations (CKD-EPI) with four approved equations based on both creatinine and cystatin C with reference to Tc-99m-diethylenetriamine pentaacetate (Tc-99m-DTPA) considered as a standard.Materials and Methods:Two hundred and one patients were enrolled in the study from a private nephrology outpatient clinic(OPD), Tiruchirappalli, India. The serum creatinine and cystatin C were measured along with routine biochemistry tests. The measurement of GFR was done by Tc-99m-DTPA gates method. The estimated GFR (eGFR) were calculated using serum cystatin C and creatinine based formulae along with the new CKD-EPI formulae. All eGFR estimations were compared with the measured GFR by gates method.Results: The average measured GFR of end stage, severe, moderate, mild renal disease and normal patient groups were 10.17±2.47, 22.58±4.40, 39.05±7.06, 69.62±24.64 and 118.06±29.23 respectively. When comparing the diagnostic accuracy for predicting GFR using well established formulae, the cystatin C based formulae have shown to be highly accurate in all stages of CKD than creatinine based formulae. Among cystatin C based formulae, CKD-EPI Cystatin C had relatively better diagnostic accuracy for predicting GFR in all stages of CKD.Conclusion: CKD-EPI Cystatin C formula has unbiased and more accurate to predict GFR in all stages of CKD.Bangladesh Journal of Medical Science Vol.16(2) 2017 p.238-244

scholarly journals Serum cystatin C is an independent biomarker associated with the renal resistive index in patients with chronic kidney disease

PLoS ONE ◽  
2018 ◽  
Vol 13 (3) ◽  
pp. e0193695 ◽  
Author(s):  
Ayu Ogawa-Akiyama ◽  
Hitoshi Sugiyama ◽  
Masashi Kitagawa ◽  
Keiko Tanaka ◽  
Akifumi Onishi ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Cystatin C ◽  
Resistive Index ◽  
Renal Resistive Index ◽  
Serum Cystatin C ◽  
Serum Cystatin

The clinical research on serum cystatin-C alteration on stage II chronic kidney disease with gubenquduyishen decoction treatment

2010 ◽  
Vol 131 (3) ◽  
pp. 581-584 ◽  
Author(s):  
Feixia Dong ◽  
Jinguo Cheng ◽  
Songcang Lin ◽  
Zhen Hu ◽  
Gang Chen ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Clinical Research ◽  
Cystatin C ◽  
Stage Ii ◽  
Serum Cystatin C ◽  
Serum Cystatin

scholarly journals Comparison of CKD-EPI Cystatin C and Creatinine Glomerular Filtration Rate Estimation Equations in Asian Indians

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Boon Wee Teo ◽  
Charumathi Sabanayagam ◽  
Jiemin Liao ◽  
Qi Chun Toh ◽  
Sharon Saw ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Serum Creatinine ◽  
Glomerular Filtration ◽  
Cystatin C ◽  
Asian Indians ◽  
Serum Cystatin C ◽  
Hypertension Status ◽  
Serum Cystatin ◽  
Disease Epidemiology

Background. Chronic kidney disease (CKD) is identified in the general population using estimated glomerular filtration rates (eGFR) calculated from a serum creatinine-based equation, the chronic kidney disease-epidemiology collaboration (CKD-EPI) equation. Using serum cystatin C in combination may improve eGFR accuracy. We evaluated the new CKD-EPI equations incorporating cystatin C in a population of Asian Indians in classifying CKD across body mass index, diabetes, and hypertension status.Methods. We retrieved standardized serum creatinine and serum cystatin C data from a cohort of 2877 Asian Indians aged 40–80 years from the Singapore Indian Eye Study and calculated eGFR (in mL/min/1.73 m2) with the new CKD-EPI equations and serum creatinine only equation.Results. The creatinine only equation mean eGFR (88 ± 17) was similar to using spline Log cystatin C (88 ± 22). The lowest mean eGFR (81 ± 21) was obtained with the spline Log cystatin C—age, sex, and weight equation. The creatinine only equation had the fewest participants (7.1%) with eGFR <60 and spline Log cystatin C—age, sex, and weight equation had the most (16.1%).Conclusions. Using serum cystatin C resulted in widely varying eGFR which significantly affected the classification of chronic kidney disease.

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