Maternal Neural Responses to Infant Cries and Faces: Relationships with Substance Use

Correction to “Maternal neural responses to infant cries and faces: relationships with substance use”

Frontiers in Psychiatry ◽

10.3389/fpsyt.2012.00115 ◽

2013 ◽

Vol 3 ◽

Author(s):

Nicole Landi ◽

Jessica Montoya ◽

Hedy Kober ◽

Helena J. V. Rutherford ◽

W. Einar Mencl ◽

...

Keyword(s):

Substance Use ◽

Neural Responses ◽

Infant Cries

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Neural responses to negative outcomes predict success in community-based substance use treatment

Addiction ◽

10.1111/add.13734 ◽

2017 ◽

Vol 112 (5) ◽

pp. 884-896 ◽

Cited By ~ 6

Author(s):

Sarah E. Forster ◽

Peter R. Finn ◽

Joshua W. Brown

Keyword(s):

Substance Use ◽

Substance Use Treatment ◽

Negative Outcomes ◽

Neural Responses ◽

Community Based

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The Role of Social Reward and Corticostriatal Connectivity in Substance Use

10.31234/osf.io/su7vg ◽

2020 ◽

Author(s):

Daniel Sazhin ◽

Angelique Frazier ◽

Caleb River Haynes ◽

Camille Johnston ◽

Iris Ka-Yi Chat ◽

...

Keyword(s):

Substance Use ◽

Social Context ◽

Orbitofrontal Cortex ◽

Strategic Behavior ◽

Reward Processing ◽

Reward Sensitivity ◽

Social Reward ◽

Neural Responses ◽

Social Stimuli ◽

Neuroimaging Study

This report describes an ongoing R03 grant that explores the links between trait reward sensitivity, substance use, and neural responses to social and nonsocial reward. Although previous research has shown that trait reward sensitivity and neural responses to reward are linked to substance use, whether this relationship is impacted by how people process social stimuli remains unclear. We are investigating these questions via a neuroimaging study with college-aged participants, using individual difference measures that examine the relation between substance use, social context, and trait reward sensitivity with tasks that measure reward anticipation, strategic behavior, social reward consumption, and the influence of social context on reward processing. We predict that substance use will be tied to distinct patterns of striatal dysfunction. Specifically, reward hyposensitive individuals will exhibit blunted striatal responses to social and non-social reward and enhanced connectivity with the orbitofrontal cortex; in contrast, reward hypersensitive individuals will exhibit enhanced striatal responses to social and non-social reward and blunted connectivity with the orbitofrontal cortex. We also will examine the relation between self-reported reward sensitivity, substance use, and striatal responses to social reward and social context. We predict that individuals reporting the highest levels of substance use will show exaggerated striatal responses to social reward and social context, independent of self-reported reward sensitivity. Examining corticostriatal responses to reward processing will help characterize the relation between reward sensitivity, social context and substance use while providing a foundation for understanding risk factors and isolating neurocognitive mechanisms that may be targeted to increase the efficacy of interventions.

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neural responses to infant vocalizations in adult listeners

The Oxford Handbook of Voice Perception ◽

10.1093/oxfordhb/9780198743187.013.12 ◽

2018 ◽

pp. 250-276

Author(s):

Katherine S. Young ◽

Christine E. Parsons ◽

Alan Stein ◽

Peter Vuust ◽

Michelle G. Craske ◽

...

Keyword(s):

Brain Plasticity ◽

Neural Responses ◽

Parental Experience ◽

Infant Vocalizations ◽

The Social ◽

Health And Disease ◽

Biological Substrates ◽

Subcortical Regions ◽

Infant Cries ◽

Future Work

Infant vocalizations are uniquely salient sounds in our auditory environment. They attract attention and compel the listener to respond quickly and carefully. These sounds prompt a range of effortful and complex behaviours in parents, with the goal of providing life-sustaining care for their infant. The neurobiological underpinnings of this motivational state are of much interest to auditory and parenting researchers alike. Neuroimaging has afforded the opportunity to examine the biological substrates of these complex states. Functional MRI (fMRI) studies have identified a network of cortical and subcortical regions that are reactive to infant cries. This ‘parental brain’ is a combination of regions of the ‘social brain’ (temporal and frontal lobe areas) and subcortical ‘survival’ regions. Temporally sensitive neuroimaging techniques (magnetoencephalography, MEG and local field potentials, LFPs) are beginning to illuminate the dynamic nature of activity among these regions, with findings demonstrating early (50–200 ms) identification of infant cries in the periaqueductal grey and orbitofrontal cortex that may support rapid orientating responses. Emerging work investigating parental experience-dependent brain plasticity suggests associations between various aspects of parenting behaviour and adaptations in fronto-amygdala circuitry. Future work combining levels of analyses in longitudinal designs may lead to a better understanding of caregiving behaviour in health and disease.

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