scholarly journals The Importance of Sensory Processing in Mental Health: A Proposed Addition to the Research Domain Criteria (RDoC) and Suggestions for RDoC 2.0

2019 ◽  
Vol 10 ◽  
Author(s):  
Laura A. Harrison ◽  
Anastasiya Kats ◽  
Marian E. Williams ◽  
Lisa Aziz-Zadeh
Keyword(s):  
Mental Health ◽  
Sensory Processing ◽  
Research Domain Criteria ◽  
Research Domain

The Psychophysiology of Anxiety and Mood Disorders

2017 ◽  
Vol 225 (3) ◽  
pp. 175-188 ◽  
Author(s):  
Peter J. Lang ◽  
Lisa M. McTeague ◽  
Margaret M. Bradley
Keyword(s):  
Mental Health ◽  
Heart Rate ◽  
Brain Function ◽  
Physiological Reactivity ◽  
Research Domain Criteria ◽  
Diagnostic Systems ◽  
Psychophysiological Reactivity ◽  
Diagnostic Categories ◽  
New Research ◽  
Research Domain

Abstract. Several decades of research are reviewed, assessing patterns of psychophysiological reactivity in anxiety patients responding to a fear/threat imagery challenge. Findings show substantive differences in these measures within principal diagnostic categories, questioning the reliability and categorical specificity of current diagnostic systems. Following a new research framework (US National Institute of Mental Health [NIMH], Research Domain Criteria [RDoC]; Cuthbert & Insel, 2013 ), dimensional patterns of physiological reactivity are explored in a large sample of anxiety and mood disorder patients. Patients’ responses (e.g., startle reflex, heart rate) during fear/threat imagery varied significantly with higher questionnaire measured “negative affect,” stress history, and overall life dysfunction – bio-marking disorder groups, independent of Diagnostic and Statistical Manuals (DSM). The review concludes with a description of new research, currently underway, exploring brain function indices (structure activation, circuit connectivity) as potential biological classifiers (collectively with the reflex physiology) of anxiety and mood pathology.

Vergleich von kategorialer und dimensionaler Analyse bei Angststörungen

2020 ◽  
Vol 88 (05) ◽  
pp. 291-292
Keyword(s):  
Mental Health ◽  
Research Domain Criteria ◽  
Dsm Iv ◽  
Dimensionale Analyse ◽  
Research Domain

Zur Diagnose von Patienten mit Angststörungen existieren zwei unterschiedliche analytische Ansätze: ein kategorialer, der auf dem DSM-IV beruht und eine dimensionale Analyse, die auf den Research Domain Criteria (einer Initiative des National Institute of Mental Health) basiert. Es ist bisher nicht bekannt, ob die beiden Ansätze unterschiedliche oder ähnliche Informationen bezüglich der Diagnose von Personen mit Angststörungen liefern.

scholarly journals The role of RDoC in future classification of mental disorders

2020 ◽  
Vol 22 (1) ◽  
pp. 81-85 ◽  
Keyword(s):  
Mental Health ◽  
Affective Behavior ◽  
Research Domain Criteria ◽  
Computational Approaches ◽  
Diagnostic Categories ◽  
Key Features ◽  
Study Designs ◽  
Research Domain

The Research Domain Criteria (RDoC) project constitutes a translational framework for psychopathology research, initiated by the National Institute of Mental Health in an attempt to provide new avenues for research to circumvent problems emerging from the use of symptom-based diagnostic categories in diagnosing disorders. The RDoC alternative is a focus on psychopathology based on dimensions simultaneously defined by observable behavior (including quantitative measures of cognitive or affective behavior) and neurobiological measures. Key features of the RDoC framework include an emphasis on functional dimensions that range from normal to abnormal, integration of multiple measures in study designs (which can foster computational approaches), and high priority on studies of neurodevelopment and environmental influences (and their interaction) that can contribute to advances in understanding the etiology of disorders throughout the lifespan. The paper highlights key implications for ways in which RDoC can contribute to future ideas about classification, as well as some of the considerations involved in translating basic behavioral and neuroscience data to psychopathology.

Research Domain Criteria and OCD

2017 ◽  
Author(s):  
Eyal Kalanthroff ◽  
Gideon E. Anholt ◽  
Helen Blair Simpson
Keyword(s):  
Mental Health ◽  
United States ◽  
Mental Disorders ◽  
The United States ◽  
Self Report ◽  
Research Domain Criteria ◽  
Diagnostic Systems ◽  
Behavioral Measures ◽  
Research Domain

This chapter discusses the Research Domain Criteria (RDoC) project, an initiative of the National Institutes of Mental Health (NIMH) of the United States to develop for research purposes new ways of classifying mental disorders based on dimensions of observable behavior and neurobiological measures, and explores how the hallmark symptoms of OCD (obsessions, compulsions, and anxiety) can be mapped onto RDoC domains. Unlike current categorical diagnostic systems (e.g., DSM), RDoC seeks to integrate many levels of information (from genomics to self-report) to validate dimensions defined by neurobiology and behavioral measures that cut across current disorder categories. The chapter explores, for heuristic reasons, how the RDoC matrix might be used to elucidate the neurobehavioral domains of dysfunction that lead to the characteristic symptoms of OCD. It then selectively reviews the OCD literature from the perspective of the RDoC domains, aiming to guide future transdiagnostic studies to examine specific neurobehavioral domains across disorders.

The National Institute of Mental Health Research Domain Criteria

2020 ◽  
pp. 62-72
Author(s):  
Charles A. Sanislow ◽  
Sarah E. Morris ◽  
Jennifer Pacheco ◽  
Bruce N. Cuthbert
Keyword(s):  
Mental Health ◽  
Clinical Symptoms ◽  
Scientific Progress ◽  
The United States ◽  
Mental Health Research ◽  
Research Domain Criteria ◽  
Behavioural Science ◽  
Integrative Research ◽  
Clinically Significant ◽  
Research Domain

The United States National Institute of Mental Health (NIMH) Research Domain Criteria (RDoC) initiative offers a framework to facilitate integrative research to clarify core mechanisms of human mental distress and dysfunction. The RDoC was developed to provide an alternative to research, designed around clinical syndromes based on descriptive diagnosis. Rather than beginning with a syndrome and then working ‘down’ to clarify mechanisms, the aim of the RDoC is to guide research that begins with disruptions in neurobiological and behavioural mechanisms, and then works across systems to clarify connections among such disruptions and clinical symptoms. The RDoC also departs from widely accepted categorical diagnoses, instead advocating a dimensional account of clinically significant variance in disrupted mechanisms and symptoms. The need for the RDoC stemmed from the realization that psychopathology research was not keeping pace with advances in clinical neuroscience and behavioural science, and the recognition that the cycle of scientific progress has been hampered by the instantiation of DSM diagnoses as the starting point of psychiatric research design. This chapter details the rationale and development of the RDoC and describes their structure. Some practical considerations and theoretical matters for implementing the RDoC alternative are considered.

Searching for the Big Pictures

2020 ◽  
Vol 15 (3) ◽  
pp. 817-830
Author(s):  
Stephen K. Reed
Keyword(s):  
Mental Health ◽  
Artificial Intelligence ◽  
Cognitive Psychology ◽  
Mental Health Research ◽  
Practical Significance ◽  
Research Domain Criteria ◽  
General Audience ◽  
Formal Ontologies ◽  
Psychological Knowledge ◽  
Research Domain

My goal in searching for the big pictures is to discover novel ways of organizing information in psychology that will have both theoretical and practical significance. The first section lists my reasons for writing each of five articles. The second section discusses an additional five articles that integrate advancements in artificial intelligence and cognitive psychology. The following two sections elaborate on my collaboration with ontologists to use formal ontologies to organize psychological knowledge, including the National Institute of Mental Health Research Domain Criteria, for formulating a biological basis for mental illness. I next discuss strategies for writing integrative articles. The following section describes the helpfulness of the integrations for making psychology relevant to a general audience. I conclude with recommendations for creating breadth in doctoral training.

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