scholarly journals Abnormal Ventral and Dorsal Attention Network Activity during Single and Dual Target Detection in Schizophrenia

2016 ◽  
Vol 7 ◽  
Author(s):  
Amy M. Jimenez ◽  
Junghee Lee ◽  
Jonathan K. Wynn ◽  
Mark S. Cohen ◽  
Stephen A. Engel ◽  
...  
Keyword(s):  
Target Detection ◽  
Network Activity ◽  
Attention Network ◽  
Dorsal Attention Network ◽  
Dual Target

scholarly journals Predicting an individual’s dorsal attention network activity from functional connectivity fingerprints

2019 ◽  
Vol 122 (1) ◽  
pp. 232-240 ◽  
Author(s):  
David E. Osher ◽  
James A. Brissenden ◽  
David C. Somers
Keyword(s):  
Functional Connectivity ◽  
Computational Models ◽  
Large Degree ◽  
Network Activity ◽  
Connectivity Pattern ◽  
Standard Group ◽  
Activation Pattern ◽  
Functional Responses ◽  
Attention Network ◽  
Dorsal Attention Network

The cortical dorsal attention network (DAN) is a set of parietal and frontal regions that support a wide variety of attentionally demanding tasks. Whereas attentional deployment reliably drives DAN activity across subjects, there is a large degree of variation in the activation pattern in individual subjects. We hypothesize that a subject’s own idiosyncratic pattern of cortical DAN activity can be predicted from that subject’s own unique pattern of functional connectivity. By modeling task activation as a function of whole brain connectivity patterns, we are able to define the connectivity fingerprints for the frontal and parietal DAN, and use it to predict a subject’s characteristic DAN activation pattern with high accuracy. These predictions outperform the standard group-average benchmark and predict a subject’s own activation pattern above and beyond predictions from another subject’s connectivity pattern. Thus an individual’s distinctive connectivity pattern accounts for substantial variance in DAN functional responses. Last, we show that the set of connections that predict cortical DAN responses, the frontal and parietal DAN connectivity fingerprints, is predominantly composed of other coactive regions, including regions outside of the DAN including occipital and temporal visual cortices. These connectivity fingerprints represent defining computational characteristics of the DAN, delineating which voxels are or are not capable of exerting top-down attentional bias to other regions of the brain. NEW & NOTEWORTHY The dorsal attention network (DAN) is a set of regions in frontoparietal cortex that reliably activate during attentional tasks. We designed computational models that predict the degree of an individual’s DAN activation using their resting-state connectivity pattern alone. This uncovered the connectivity fingerprints of the DAN, which define it so well that we can predict how a voxel will respond to an attentional task given only its pattern of connectivity, with outstanding accuracy.

scholarly journals The lateral intraparietal sulcus takes viewpoint changes into account during memory-guided attention in natural scenes

2021 ◽  
Vol 226 (4) ◽  
pp. 989-1006
Author(s):  
Ilenia Salsano ◽  
Valerio Santangelo ◽  
Emiliano Macaluso
Keyword(s):  
Spatial Information ◽  
Temporal Cortex ◽  
Independent Effect ◽  
Long Term Memory ◽  
Natural Scenes ◽  
Behavioral Measures ◽  
Attention Network ◽  
Low Contrast ◽  
Dorsal Attention Network

AbstractPrevious studies demonstrated that long-term memory related to object-position in natural scenes guides visuo-spatial attention during subsequent search. Memory-guided attention has been associated with the activation of memory regions (the medial-temporal cortex) and with the fronto-parietal attention network. Notably, these circuits represent external locations with different frames of reference: egocentric (i.e., eyes/head-centered) in the dorsal attention network vs. allocentric (i.e., world/scene-centered) in the medial temporal cortex. Here we used behavioral measures and fMRI to assess the contribution of egocentric and allocentric spatial information during memory-guided attention. At encoding, participants were presented with real-world scenes and asked to search for and memorize the location of a high-contrast target superimposed in half of the scenes. At retrieval, participants viewed again the same scenes, now all including a low-contrast target. In scenes that included the target at encoding, the target was presented at the same scene-location. Critically, scenes were now shown either from the same or different viewpoint compared with encoding. This resulted in a memory-by-view design (target seen/unseen x same/different view), which allowed us teasing apart the role of allocentric vs. egocentric signals during memory-guided attention. Retrieval-related results showed greater search-accuracy for seen than unseen targets, both in the same and different views, indicating that memory contributes to visual search notwithstanding perspective changes. This view-change independent effect was associated with the activation of the left lateral intra-parietal sulcus. Our results demonstrate that this parietal region mediates memory-guided attention by taking into account allocentric/scene-centered information about the objects' position in the external world.

scholarly journals Brain Functional Magnetic Resonance Imaging Highlights Altered Connections and Functional Networks in Patients With Hypertension

Hypertension ◽  
2020 ◽  
Vol 76 (5) ◽  
pp. 1480-1490 ◽  
Author(s):  
Lorenzo Carnevale ◽  
Angelo Maffei ◽  
Alessandro Landolfi ◽  
Giovanni Grillea ◽  
Daniela Carnevale ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Resting State ◽  
Diffusion Tensor ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Attention Network ◽  
Dorsal Attention Network ◽  
The Brain

Hypertension is one of the main risk factors for vascular dementia and Alzheimer disease. To predict the onset of these diseases, it is necessary to develop tools to detect the early effects of vascular risk factors on the brain. Resting-state functional magnetic resonance imaging can investigate how the brain modulates its resting activity and analyze how hypertension impacts cerebral function. Here, we used resting-state functional magnetic resonance imaging to explore brain functional-hemodynamic coupling across different regions and their connectivity in patients with hypertension, as compared to subjects with normotension. In addition, we leveraged multimodal imaging to identify the signature of hypertension injury on the brain. Our study included 37 subjects (18 normotensives and 19 hypertensives), characterized by microstructural integrity by diffusion tensor imaging and cognitive profile, who were subjected to resting-state functional magnetic resonance imaging analysis. We mapped brain functional connectivity networks and evaluated the connectivity differences among regions, identifying the altered connections in patients with hypertension compared with subjects with normotension in the (1) dorsal attention network and sensorimotor network; (2) dorsal attention network and visual network; (3) dorsal attention network and frontoparietal network. Then we tested how diffusion tensor imaging fractional anisotropy of superior longitudinal fasciculus correlates with the connections between dorsal attention network and default mode network and Montreal Cognitive Assessment scores with a widespread network of functional connections. Finally, based on our correlation analysis, we applied a feature selection to highlight those most relevant to describing brain injury in patients with hypertension. Our multimodal imaging data showed that hypertensive brains present a network of functional connectivity alterations that correlate with cognitive dysfunction and microstructural integrity. Registration— URL: https://www.clinicaltrials.gov ; Unique identifier: NCT02310217.

Aberrant dorsal attention network homogeneity in patients with right temporal lobe epilepsy

2020 ◽  
Vol 111 ◽  
pp. 107278
Author(s):  
Sangyu Zhou ◽  
Pingan Xiong ◽  
Hongwei Ren ◽  
Wei Tan ◽  
Yanguo Yan ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Attention Network ◽  
Dorsal Attention Network ◽  
Right Temporal Lobe Epilepsy

scholarly journals Temporal circuit of macroscale dynamic brain activity supports human consciousness

2020 ◽  
Vol 6 (11) ◽  
pp. eaaz0087 ◽  
Author(s):  
Zirui Huang ◽  
Jun Zhang ◽  
Jinsong Wu ◽  
George A. Mashour ◽  
Anthony G. Hudetz
Keyword(s):  
Default Mode Network ◽  
Functional Role ◽  
Brain Activity ◽  
Human Consciousness ◽  
Attention Network ◽  
Attention Networks ◽  
Default Mode ◽  
Dorsal Attention Network ◽  
Brain States

The ongoing stream of human consciousness relies on two distinct cortical systems, the default mode network and the dorsal attention network, which alternate their activity in an anticorrelated manner. We examined how the two systems are regulated in the conscious brain and how they are disrupted when consciousness is diminished. We provide evidence for a “temporal circuit” characterized by a set of trajectories along which dynamic brain activity occurs. We demonstrate that the transitions between default mode and dorsal attention networks are embedded in this temporal circuit, in which a balanced reciprocal accessibility of brain states is characteristic of consciousness. Conversely, isolation of the default mode and dorsal attention networks from the temporal circuit is associated with unresponsiveness of diverse etiologies. These findings advance the foundational understanding of the functional role of anticorrelated systems in consciousness.

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