scholarly journals Maintenance of Cotton Leaf Curl Multan Betasatellite by Tomato Leaf Curl New Delhi Virus—Analysis by Mutation

2017 ◽  
Vol 8 ◽  
Author(s):  
Zafar Iqbal ◽  
Muhammad Shafiq ◽  
Irfan Ali ◽  
Shahid Mansoor ◽  
Rob W. Briddon
Keyword(s):  
Tomato Leaf ◽  
Cotton Leaf ◽  
New Delhi ◽  
Tomato Leaf Curl ◽  
Leaf Curl

scholarly journals In silico evaluation of molecular virus–virus interactions taking place between Cotton leaf curl Kokhran virus- Burewala strain and Tomato leaf curl New Delhi virus

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e12018
Author(s):  
Nida Fatima Ali ◽  
Rehan Zafar Paracha ◽  
Muhammad Tahir
Keyword(s):  
Protein Structures ◽  
Protein Docking ◽  
Tomato Leaf ◽  
Replication Initiation ◽  
Electrostatic Energy ◽  
Cotton Leaf ◽  
New Delhi ◽  
Virus Interactions ◽  
Tomato Leaf Curl ◽  
Leaf Curl

Background Cotton leaf curl disease (CLCuD) is a disease of cotton caused by begomoviruses, leading to a drastic loss in the annual yield of the crop. Pakistan has suffered two epidemics of this disease leading to the loss of billions in annual exports. The speculation that a third epidemic of CLCuD may result as consequence of the frequent occurrence of Tomato leaf curl New Delhi virus (ToLCNDV) and Cotton leaf curl Kokhran Virus-Burewala Strain (CLCuKoV-Bu) in CLCuD infected samples, demand that the interactions taking between the two viruses be properly evaluated. This study is designed to assess virus-virus interactions at the molecular level and determine the type of co-infection taking place. Methods Based on the amino acid sequences of the gene products of both CLCuKoV-Bu and ToLCNDV, protein structures were generated using different software, i.e., MODELLER, I-TASSER, QUARKS, LOMETS and RAPTORX. A consensus model for each protein was selected after model quality assessment using ERRAT, QMEANDisCo, PROCHECK Z-Score and Ramachandran plot analysis. The active and passive residues in the protein structures were identified using the CPORT server. Protein–Protein Docking was done using the HADDOCK webserver, and 169 Protein–Protein Interaction (PPIs) were performed between the proteins of the two viruses. The docked complexes were submitted to the PRODIGY server to identify the interacting residues between the complexes. The strongest interactions were determined based on the HADDOCK Score, Desolvation energy, Van der Waals Energy, Restraint Violation Energy, Electrostatic Energy, Buried Surface Area and Restraint Violation Energy, Binding Affinity and Dissociation constant (Kd). A total of 50 ns Molecular Dynamic simulations were performed on complexes that exhibited the strongest affinity in order to validate the stability of the complexes, and to remove any steric hindrances that may exist within the structures. Results Our results indicate significant interactions taking place between the proteins of the two viruses. Out of all the interactions, the strongest were observed between the Replication Initiation protein (Rep) of CLCuKoV-Bu with the Movement protein (MP), Nuclear Shuttle Protein (NSP) of ToLCNDV (DNA-B), while the weakest were seen between the Replication Enhancer protein (REn) of CLCuKoV-Bu with the REn protein of ToLCNDV. The residues identified to be taking a part in interaction belonged to domains having a pivotal role in the viral life cycle and pathogenicity. It maybe deduced that the two viruses exhibit antagonistic behavior towards each other, and the type of infection may be categorised as a type of Super Infection Exclusion (SIE) or homologous interference. However, further experimentation, in the form of transient expression analysis, is needed to confirm the nature of these interactions and increase our understanding of the direct interactions taking place between two viruses.

scholarly journals Frequent Occurrence of Tomato Leaf Curl New Delhi Virus in Cotton Leaf Curl Disease Affected Cotton in Pakistan

PLoS ONE ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. e0155520 ◽  
Author(s):  
Syed Shan-e-Ali Zaidi ◽  
Muhammad Shafiq ◽  
Imran Amin ◽  
Brian E. Scheffler ◽  
Jodi A. Scheffler ◽  
...  
Keyword(s):  
Tomato Leaf ◽  
Frequent Occurrence ◽  
Cotton Leaf ◽  
New Delhi ◽  
Cotton Leaf Curl Disease ◽  
Tomato Leaf Curl ◽  
Leaf Curl Disease ◽  
Leaf Curl

Potato apical leaf curl disease: current status and perspectives on a disease caused by tomato leaf curl New Delhi virus

2021 ◽  
Author(s):  
Ravinder Kumar ◽  
Rahul Kumar Tiwari ◽  
Arjunan Jeevalatha ◽  
Sundaresha Siddappa ◽  
Mohd. Abas Shah ◽  
...  
Keyword(s):  
Tomato Leaf ◽  
Current Status ◽  
New Delhi ◽  
Apical Leaf ◽  
Tomato Leaf Curl ◽  
Leaf Curl Disease ◽  
Leaf Curl

Tomato leaf curl New Delhi virus. [Distribution map].

2016 ◽  
Author(s):  
Keyword(s):  
Tamil Nadu ◽  
Uttar Pradesh ◽  
Tomato Leaf ◽  
New Delhi ◽  
Distribution Map ◽  
Tomato Leaf Curl ◽  
Virus Distribution ◽  
New Distribution ◽  
Distribution In Europe ◽  
Leaf Curl

Abstract A new distribution map is provided for Tomato leaf curl New Delhi virus. Geminiviridae: Begomovirus. Hosts: tomato (Solanum lycopersicum) and other Solanaceae such as aubergine (S. melongena), potato (S. tuberosum), Capsicum spp. and Cucurbitaceae. Information is given on the geographical distribution in Europe (Italy, Sicily, Spain, Mainland Spain), Asia (Bangladesh, India, Andhra Pradesh, Delhi, Gujarat, Haryana, Karnataka, Maharashtra, Punjab, Tamil Nadu, Uttar Pradesh, West Bengal, Indonesia, Java, Iran, Pakistan, Philippines, Sri Lanka, Taiwan and Thailand) and Africa (Tunisia).

Diagnostic methods of tomato leaf curl New Delhi virus in Russian Federation

2021 ◽  
Author(s):  
E. Lozovaya ◽  
Y. Prikhodko ◽  
T. Zhivaeva ◽  
E. Karimova ◽  
Y. Shneyder
Keyword(s):  
Russian Federation ◽  
Tomato Leaf ◽  
Diagnostic Methods ◽  
New Delhi ◽  
Tomato Leaf Curl ◽  
Leaf Curl

Emergence of tomato leaf curl New Delhi virus in Italy: estimation of incidence and genetic diversity

2019 ◽  
Vol 68 (3) ◽  
pp. 601-608 ◽  
Author(s):  
S. Panno ◽  
A. G. Caruso ◽  
E. Troiano ◽  
M. Luigi ◽  
A. Manglli ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Tomato Leaf ◽  
New Delhi ◽  
Tomato Leaf Curl ◽  
Leaf Curl
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