scholarly journals Mild Neonatal Brain Hypoxia-Ischemia in Very Immature Rats Causes Long-Term Behavioral and Cerebellar Abnormalities at Adulthood

2019 ◽  
Vol 10 ◽  
Author(s):  
Eduardo Farias Sanches ◽  
Yohan van de Looij ◽  
Audrey Toulotte ◽  
Stéphane Vladimir Sizonenko ◽  
Hongxia Lei
Keyword(s):  
Neonatal Brain ◽  
Brain Hypoxia ◽  
Immature Rats ◽  
Hypoxia Ischemia

scholarly journals Efferocytosis Mediated Modulation of Injury after Neonatal Brain Hypoxia-Ischemia

Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1025
Author(s):  
Jana Krystofova Mike ◽  
Donna Marie Ferriero
Keyword(s):  
Therapeutic Potential ◽  
Significant Progress ◽  
Neonatal Brain ◽  
Brain Hypoxia ◽  
Homeostatic Process ◽  
Promising Target ◽  
Cellular Debris ◽  
Hypoxia Ischemia ◽  
The Brain

Neonatal brain hypoxia-ischemia (HI) is a leading cause of morbidity and long-term disabilities in children. While we have made significant progress in describing HI mechanisms, the limited therapies currently offered for HI treatment in the clinical setting stress the importance of discovering new targetable pathways. Efferocytosis is an immunoregulatory and homeostatic process of clearance of apoptotic cells (AC) and cellular debris, best described in the brain during neurodevelopment. The therapeutic potential of stimulating defective efferocytosis has been recognized in neurodegenerative diseases. In this review, we will explore the involvement of efferocytosis after a stroke and HI as a promising target for new HI therapies.

scholarly journals Sex-dependent consequences of neonatal brain hypoxia-ischemia in the rat

2016 ◽  
Vol 95 (1-2) ◽  
pp. 409-421 ◽  
Author(s):  
Carlos Alexandre Netto ◽  
Eduardo Sanches ◽  
Felipe Kawa Odorcyk ◽  
Luz Elena Duran-Carabali ◽  
Simone Nardin Weis
Keyword(s):  
Neonatal Brain ◽  
Brain Hypoxia ◽  
Hypoxia Ischemia

Pregnancy swimming causes short- and long-term neuroprotection against hypoxia–ischemia in very immature rats

2017 ◽  
Vol 82 (3) ◽  
pp. 544-553 ◽  
Author(s):  
Eduardo Farias Sanches ◽  
Luz Elena Durán-Carabali ◽  
Andrea Tosta ◽  
Fabrício Nicola ◽  
Felipe Schmitz ◽  
...  
Keyword(s):  
Immature Rats ◽  
Hypoxia Ischemia ◽  
Short And Long Term

scholarly journals Deferoxamine Therapy in a Mouse Model of Neonatal Brain Hypoxia-Ischemia• 1853

1998 ◽  
Vol 43 ◽  
pp. 316-316
Author(s):  
Joseph Becker ◽  
Dean Sarco ◽  
Heather Fullerton Chetkovich ◽  
R Ann Sheldon ◽  
Donna M Ferriero
Keyword(s):  
Mouse Model ◽  
Neonatal Brain ◽  
Brain Hypoxia ◽  
Hypoxia Ischemia

scholarly journals Changes in arginase isoforms in a murine model of neonatal brain hypoxia–ischemia

2020 ◽  
Author(s):  
Jana K. Mike ◽  
Praneeti Pathipati ◽  
R. Ann Sheldon ◽  
Donna M. Ferriero
Keyword(s):  
Murine Model ◽  
Neonatal Brain ◽  
Brain Hypoxia ◽  
Hypoxia Ischemia

Delayed IGF-1 treatment reduced long-term hypoxia–ischemia-induced brain damage and improved behavior recovery of immature rats

2009 ◽  
Vol 31 (5) ◽  
pp. 483-489 ◽  
Author(s):  
Jin Zhong ◽  
Limin Zhao ◽  
Yansheng Du ◽  
Gang Wei ◽  
Wei-Guo Yao ◽  
...  
Keyword(s):  
Brain Damage ◽  
Immature Rats ◽  
Hypoxia Ischemia

Oxygen treatment after perinatal hypoxia-ischemia reduces neuronal damage at short survival times, but worsens injury with long-term survival

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S444-S444 ◽  
Author(s):  
Kristin M Noppens ◽  
J Regino Perez-Polo ◽  
David K Rassin ◽  
Karin N Westlund ◽  
Roderic Fabian ◽  
...  
Keyword(s):  
Neuronal Damage ◽  
Perinatal Hypoxia ◽  
Survival Times ◽  
Term Survival ◽  
Long Term Survival ◽  
Short Survival ◽  
Oxygen Treatment ◽  
Hypoxia Ischemia
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