Pregnancy swimming causes short- and long-term neuroprotection against hypoxia–ischemia in very immature rats

2017 ◽  
Vol 82 (3) ◽  
pp. 544-553 ◽  
Author(s):  
Eduardo Farias Sanches ◽  
Luz Elena Durán-Carabali ◽  
Andrea Tosta ◽  
Fabrício Nicola ◽  
Felipe Schmitz ◽  
...  
1998 ◽  
Vol 43 (6) ◽  
pp. 738-745 ◽  
Author(s):  
Elsa Bona ◽  
Henrik Hagberg ◽  
Else Marit Løberg ◽  
Ralph Bågenholm ◽  
Marianne Thoresen

1990 ◽  
Vol 124 (2) ◽  
pp. 247-253 ◽  
Author(s):  
H. M. A. Meijs-Roelofs ◽  
W. A. van Cappellen ◽  
E. C. M. van Leeuwen ◽  
P. Kramer

ABSTRACT The effects of the suppression of the high gonadotrophin concentrations normally present by the end of the second week of life on ovarian follicle dynamics were studied in immature rats. Gonadotrophins were suppressed by treatment with an LHRH antagonist (LHRH-A; Org. 30276) on days 6, 9, 12 and 15, and the total population of ovarian follicles was studied at 15 and 28 days, on the day of first oestrus and on the day of oestrus at or following 90 and 300 days of age. Primordial follicles were counted and growing follicles were counted and measured. In rats treated with LHRH-A, follicle recruitment into the growing pool was clearly diminished; the number of growing follicles was significantly (P<0·01) lower up to the day of first oestrus and the pool of primordial follicles was significantly (P<0·05) larger at 15 and 28 days. Ovarian weights were significantly lower in rats treated with LHRH-A until at least 90 days of age. However, on the day of oestrus at or after 90 and 300 days of age, there were no differences in either the pool of primordial follicles or the pool of growing follicles between rats treated with LHRH-A and control rats. There was also no difference between groups in the number of fresh corpora lutea at these ages. It was concluded that the early peak in gonadotrophin concentrations in immature rats causes substantial recruitment of follicles into the growing pool. Thus, the number of follicles entering the growing pool is not solely dependent upon the size of the pool of primordial follicles but is clearly influenced by the level of circulating gonadotrophins. In contrast, the large gonadotrophic stimulation that normally takes place during the second and third week of life is neither a prerequisite for functional sexual maturation nor for later cyclic function. Shortly before the time of first ovulation a tight control of follicle dynamics is established which is largely independent of previous gonadotrophin concentrations and follicle dynamics. Journal of Endocrinology (1990) 124, 247–253


2019 ◽  
Vol 10 ◽  
Author(s):  
Eduardo Farias Sanches ◽  
Yohan van de Looij ◽  
Audrey Toulotte ◽  
Stéphane Vladimir Sizonenko ◽  
Hongxia Lei

1995 ◽  
Vol 38 (1) ◽  
pp. 113-118 ◽  
Author(s):  
Helmut Rumpel ◽  
Reto Buchli ◽  
Jochen Gehrmann ◽  
Adriano Aguzzi ◽  
Oscar Illi ◽  
...  

2009 ◽  
Vol 31 (5) ◽  
pp. 483-489 ◽  
Author(s):  
Jin Zhong ◽  
Limin Zhao ◽  
Yansheng Du ◽  
Gang Wei ◽  
Wei-Guo Yao ◽  
...  

Swiss Surgery ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Robert ◽  
Mariéthoz ◽  
Pache ◽  
Bertin ◽  
Caulfield ◽  
...  

Objective: Approximately one out of five patients with Graves' disease (GD) undergoes a thyroidectomy after a mean period of 18 months of medical treatment. This retrospective and non-randomized study from a teaching hospital compares short- and long-term results of total (TT) and subtotal thyroidectomies (ST) for this disease. Methods: From 1987 to 1997, 94 patients were operated for GD. Thirty-three patients underwent a TT (mostly since 1993) and 61 a ST (keeping 4 to 8 grams of thyroid tissue - mean 6 g). All patients had received propylthiouracil and/or neo-mercazole and were in a euthyroid state at the time of surgery; they also took potassium iodide (lugol) for ten days before surgery. Results: There were no deaths. Transient hypocalcemia (< 3 months) occurred in 32 patients (15 TT and 17 ST) and persistent hypocalcemia in 8 having had TT. Two patients developed transient recurrent laryngeal nerve palsy after ST (< 3 months). After a median follow-up period of seven years (1-15) with five patients lost to follow-up, 41 patients having had a ST are in a hypothyroid state (73%), thirteen are euthyroid (23%), and two suffered recurrent hyperthyroidism, requiring completion of thyroidectomy. All 33 patients having had TT - with follow-ups averaging two years (0.5-8) - are receiving thyroxin substitution. Conclusions: There were no instances of persistent recurrent laryngeal nerve palsy in either group, but persistent hypoparathyroidism occurred more frequently after TT. Long after ST, hypothyroidism developed in nearly three of four cases, whereas euthyroidy was maintained in only one-fourth; recurrent hyperthyroidy was rare.


Author(s):  
Ian Neath ◽  
Jean Saint-Aubin ◽  
Tamra J. Bireta ◽  
Andrew J. Gabel ◽  
Chelsea G. Hudson ◽  
...  

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