scholarly journals Vagal modulation of resting heart rate in rats: the role of stress, psychosocial factors, and physical exercise

2014 ◽  
Vol 5 ◽  
Author(s):  
Luca Carnevali ◽  
Andrea Sgoifo
Keyword(s):  
Heart Rate ◽  
Physical Exercise ◽  
Psychosocial Factors ◽  
Resting Heart Rate ◽  
Vagal Modulation

scholarly journals The role of heart rate and ivabradine in acute heart failure

2019 ◽  
Vol 89 (3) ◽  
Author(s):  
Edoardo Sciatti ◽  
Enrico Vizzardi ◽  
Ivano Bonadei ◽  
Lucia Dallapellegrina ◽  
Valentina Carubelli
Keyword(s):  
Heart Failure ◽  
Heart Rate ◽  
Healthy Subjects ◽  
Beta Blockers ◽  
Resting Heart Rate ◽  
Powerful Predictor ◽  
Treatment Target ◽  
Reduced Ejection Fraction ◽  
Lowering Drug

Resting heart rate (HR) is considered a powerful predictor of mortality both in healthy subjects and in cardiovascular (CV) patients, including those affected by heart failure (HF). Its reduction below 70 bpm is the treatment target in chronic HF with reduced ejection fraction (HFrEF) when sinus rhythm is present. In acute HF (AHF) HR is usually elevated but its role as risk marker is still unknown. Notably, in unstable patients, beta-blockers can be reduced or stopped, thus enhancing this phenomenon. Moreover, some data in literature suggest that HR reduction during hospitalization or HR at discharge or in the vulnerable phase after it are more predictive of early-term events and may be therapeutic targets. On the other hand, ivabradine is a pure HR-lowering drug with no effects on inotropism. Its role in the AHF setting has been recently investigated and is the object of this review.

scholarly journals Protective Role of Resting Heart Rate on All-Cause and Cardiovascular Disease Mortality

2013 ◽  
Vol 88 (12) ◽  
pp. 1420-1426 ◽  
Author(s):  
Arpit Saxena ◽  
Dawn Minton ◽  
Duck-chul Lee ◽  
Xuemei Sui ◽  
Raja Fayad ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Heart Rate ◽  
Protective Role ◽  
Resting Heart Rate ◽  
Cardiovascular Disease Mortality ◽  
Disease Mortality

scholarly journals BRADYCARDIA IN ATHLETES: DOES THE TYPE OF SPORT MAKE ANY DIFFERENCE? – A SYSTEMATIC REVIEW

2020 ◽  
Vol 26 (5) ◽  
pp. 449-453
Author(s):  
Michelle Teles Morlin ◽  
Carlos Janssen Gomes da Cruz ◽  
Paula Beatriz Silvestre Melo ◽  
Guilherme Henrique Ramos Lopes ◽  
Edgar de Melo Keene Von Koening Soares ◽  
...  
Keyword(s):  
Heart Rate ◽  
English Language ◽  
Female Athletes ◽  
Cardiac Structure ◽  
Resting Heart Rate ◽  
Level Of Evidence ◽  
Cardiac Responses ◽  
Vagal Modulation ◽  
Slow Heart Rate ◽  
Pharmacological Blockade

ABSTRACT Bradycardia in athletes can range from moderate to severe, and the factors that contribute to slow heart rate are complex. Studies investigating the mechanisms associated with this condition are controversial, and may be linked to the form of exercise practiced. A systematic literature review was conducted to discuss bradycardia mechanisms in athletes who practice different forms of sport. The databases consulted were Pubmed (MEDLINE), Clinical Trials, Cochrane, Scopus, Web of Science, SciELO, Sport Discus and PEDro. The search included English language articles published up to January 2019, that evaluated athletes who practiced different forms of sport. One hundred and ninety-three articles were found, ten of which met the inclusion criteria, with 1549 male and female athletes who practiced diverse forms of sport. Resting heart rate and cardiac structure were studied in association with the form of sport practiced, through heart rate variability, electrocardiogram, echocardiogram and pharmacological blockade. The studies suggest that a slow resting heart rate cannot be explained by increased vagal modulation alone, but also includes changes in cardiac structure. According to the studies, different sports seem to produce different cardiac responses, and the bradycardia found in athletes can be explained by non-autonomic and autonomic mechanisms, depending on the type of effort or the form of sport practiced. However, the mechanism underlying the slow heart rate in each form of sport is still unclear. Level of evidence II; Prognostic studies - Investigating the effect of a patient characteristic on the outcome of disease.

scholarly journals Association of Psychosocial Factors With Short‐Term Resting Heart Rate Variability: The Atherosclerosis Risk in Communities Study

2021 ◽  
Vol 10 (5) ◽  
Author(s):  
Anish S. Shah ◽  
Alvaro Alonso ◽  
Eric A. Whitsel ◽  
Elsayed Z. Soliman ◽  
Viola Vaccarino ◽  
...  
Keyword(s):  
Social Support ◽  
Heart Rate ◽  
Psychosocial Factors ◽  
Perceived Social Support ◽  
Low Frequency ◽  
Resting Heart Rate ◽  
Short Term ◽  
Atherosclerosis Risk In Communities ◽  
Atherosclerosis Risk ◽  
Over Time

Background Psychosocial factors predict heart disease risk, but our understanding of underlying mechanisms is limited. We sought to evaluate the physiologic correlates of psychosocial factors by measuring their relationships with heart rate variability (HRV), a measure of autonomic health, in the ARIC (Atherosclerosis Risk in Communities) study. We hypothesize that increased psychosocial stress associates with lower HRV. Methods and Results We studied 9331 participants in ARIC with short‐term HRV data at visits 2 and 4. The mean (SD) age was 54.4 (5.7) years, 55% were women, and 25% were Black. Psychosocial factors included: (1) vital exhaustion (VE), (2) anger proneness, a personality trait, and (3) perceived social support. Linear models adjusted for sociodemographic and cardiovascular risk factors. Low frequency HRV (ln ms 2 ) was significantly lower in the highest versus lowest quartiles of VE (B=−0.14, 95% CI, −0.24 to −0.05). When comparing this effect to age (B=−0.04, 95% CI, −0.05 to −0.04), the difference was equivalent to 3.8 years of accelerated aging. Perceived social support associated with lower time‐domain HRV. High VE (versus low VE) also associated with greater decreases in low frequency over time, and both anger and VE associated with greater increases in resting heart rate over time. Survival analyses were performed with Cox models, and no evidence was found that HRV explains the excess risk found with high VE and low perceived social support. Conclusions Vital exhaustion, and to a lesser extent anger and social support, were associated with worse autonomic function and greater adverse changes over time.

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